Sabia, S; Gueguen, A; Berr, C; Berkman, L; Ankri, J; Goldberg, M; ... Singh-Manoux, A; + view all Sabia, S; Gueguen, A; Berr, C; Berkman, L; Ankri, J; Goldberg, M; Zins, M; Singh-Manoux, A; - view fewer (2011) High alcohol consumption in middle-aged adults is associated with poorer cognitive performance only in the low socio-economic group. Results from the GAZEL cohort study. ADDICTION , 106 (1) 93 - 101. 10.1111/j.1360-0443.2010.03106.x.
Full text not available from this repository.
AimsTo examine the association of alcohol consumption over 10 years with cognitive performance in different socio-economic groups.DesignProspective cohort study, the French GAZEL study.SettingFrance.ParticipantsEmployees of France's national electricity and gas company.MeasurementsAlcohol intake was assessed annually, beginning in 1992, using questions on frequency and quantity of alcoholic beverages consumed in a week; used to define mean consumption and trajectory of alcohol intake over 10 years. Cognitive performance among participants aged >= 55 years (n = 4073) was assessed in 2002-04 using the Digit Symbol Substitution Test (DSST), a measure of psychomotor speed, attention and reasoning. Occupational position at age 35 and education were used as the markers of socio-economic position.FindingsAll analyses were stratified by socio-economic position. In the low occupational group, participants consuming a mean of more than 21 drinks per week had 2.1 points lower (95% CI: -3.9, -0.3) DSST score compared to those consuming four to 14 drinks per week. In participants with primary school education, the corresponding difference was 3.6 points (95% CI: -7.1, -0.0). No association between alcohol consumption and cognitive performance was observed in the intermediate and high socio-economic groups, defined using either occupation or education. Analysis of trajectories of alcohol consumption showed that in the low socio-economic groups large increase or decrease in alcohol consumption was associated with lower cognitive scores compared to stable consumption.ConclusionsOur results suggest that high alcohol consumption is associated with poorer cognitive performance only in the low socio-economic group, due possibly to greater cognitive reserve in the higher socio-economic groups.
|Title:||High alcohol consumption in middle-aged adults is associated with poorer cognitive performance only in the low socio-economic group. Results from the GAZEL cohort study|
|Keywords:||Alcohol consumption, cognition, cognitive reserve, Digit Symbol Substitution Test, socio-economic position, VASCULAR RISK-FACTORS, WHITEHALL-II, LATE-LIFE, ALZHEIMERS-DISEASE, DEMENTIA, DRINKING, MIDLIFE, IMPAIRMENT, SMOKING, METAANALYSIS|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health Care > Epidemiology and Public Health|
Archive Staff Only: edit this record