UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Browse by UCL Departments and Centres

Up a level
Export as [feed] RSS 2.0 [feed] RSS 1.0 [feed] Atom
Group by: Author | Type
Jump to: A | B | C | D | E | H | I | J | K | L | M | N | O | P | R | S | T | U | W | Z
Number of items: 93.

A

Ahmed, F and Lye, GJ and Woodley, JM (2003) Tool for the rapid evaluation of process limitation using microscale experimention. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. (pp. U218 - U219). AMER CHEMICAL SOC

Ahmed, F and Lye, GJ and Woodley, JM (2003) Tools for the rapid evaluation of process limitations using microscale experimentation. In: (Proceedings) 225th ACS National Meeting. : New Orleans, LA, USA.

Alphand, V and Carrea, G and Wohlgemouth, R and Furstoss, R and Woodley, JM (2003) Towards large-scale synthetic applications of Baeyer-Villiger monooxygenases. Trends in Biotechnology , 21 318 - 323.

Amanullah, A and Hewitt, CJ and Nienow, AW and Lee, C and Chartrain, M and Buckland, BC and Drew, SW and Woodley, JM (2003) Measurement of strain-dependent toxicity in the indene bioconversion using multiparameter flow cytometry. Biotechnology and Bioengineering , 81 (4) 405 - 420.

B

Baldascini, H and Bracewell, DG and Hoare, M (2003) Use of an ultra scale down device to predict degradation of biopharmaceuticals in recovery, purification and formulation operations. In: (Proceedings) 11th European Congress on Biotechnology, ECB 11. : Basel, Switzerland.

Baldwin, CF and Woodley, JM (2003) Oxygen limitations in the biocatalytic BVMO catalysed synthesis of lactones. In: (Proceedings) 225th ACS National Meeting. : New Orleans, LA, USA.

Baldwin, CF and Woodley, JM (2003) The role of oxygen limitation in the scale - up of biocatalytic BVMO catalysed synthesis of lactones. In: (Proceedings) 11th European Congress on Biotechnology. : Basel, Switzerland.

Baldwin, CF and Woodley, JM (2003) Whole cell biocatalytic processes for selective oxidations by Baeyer-Villiger monooxygenases. In: (Proceedings) Interdisciplinary approaches to Industrial Biocatalysis: BioCat. : Barcelona, Spain.

Booth, AJ and Sutherland, IA and Lye, GJ (2003) Modeling the performance of pilot-scale countercurrent chromatography: Scale-up predictions and experimental verification of erythromycin separation. BIOTECHNOL BIOENG , 81 (6) 640 - 649. 10.1002/bit.10508.

Bracewell, DG and Baldascini, H and Hoare, M (2003) Innovation in scale-down methodology: integrating ultra scale-down devices, modelling and visualisation. In: (Proceedings) Bio CHC-03. : Boulder Colorado, USA.

Burton, SG and Cowan, DA and Woodley, JM (2003) The ideal biocatalyst: The new approach and its application in biocatalysis process development. In: (Proceedings) 6th International Symposium on Biocatalysis and Biotransformations. : Olomouc, CZ.

C

Chan, S and S rensen, E and Titchener-Hooker, N (2003) Optimal operation of simulated moving bed chromatographic processes. In: (Proceedings) Proceedings of ECCE'4, Granada, Spain.

Chan, S and Sorensen, E and Titchener-Hooker, N (2003) Optimal operation of simulated moving bed chromatographic processes. In: (Proceedings) Proceedings of ECCE'4, Granada, Spain.

Cooke, GD and Cranenburgh, RM and Hanak, JAJ and Ward, JM (2003) A modified Escherichia coli protein production strain expressing staphylococcal nuclease, capable of autohydrolysing host nucleic acid. J BIOTECHNOL , 101 (3) 229 - 239. 10.1016/S0168-1656(02)00339-5.

D

Dalby, PA (2003) Optimising enzyme function by directed evolution. CURR OPIN STRUC BIOL , 13 (4) 500 - 505. 10.1016/S0959-440X(03)00101-5.

Dalby, PA and Aucamp, JP (2003) Dialysis Apparatus.

Doig, SD and Simpson, H and Alphand, V and Furstoss, R and Woodley, JM (2003) Characterisation of a recombinant Escherichia coli TOP10 (pQR239) whole-cell biocatalyst for stereoselective Baeyer-Villiger oxidations. Enzyme and Microbial Technology , 32 (3-4) 347 - 355.

Dunnill, P and Titchener-Hooker, NJ and Hoare, M (2003) A method and apparatus for producing a biomaterial product. GB2364.

E

Elmahdi, I and Baganz, F and Dixon, K and Harrop, T and Sugden, D and Lye, GJ (2003) Fermentation process optimisation via microwell fermentation with automated pH control. In: (Proceedings) Biochemical Engineering XII. : Boulder Colorado, USA.

Elmahdi, I and Baganz, F and Dixon, K and Harrop, T and Sugden, D and Lye, GJ (2003) pH control in microwell fermentations of S-erythraea CA340: influence on biomass growth kinetics and erythromycin biosynthesis. BIOCHEM ENG J , 16 (3) 299 - 310. 10.1016/S1369-703X(03)00073-1.

H

Henderson, B and Nair, SP and Ward, JM and Wilson, M (2003) Molecular pathogenicity of the oral opportunistic pathogen Actinobacillus actinomycetemcomitans. ANNU REV MICROBIOL , 57 29 - 55. 10.1146/annurev.micro.57.030502.090908.

Hernandez, D and Addou, S and Lee, D and Orengo, C and Shephard, EA and Phillips, IR (2003) Trimethylaminuria and a human FMO3 mutation database. HUM MUTAT , 22 (3) 209 - 213. 10.1002/humu.10252.

Hoare, M (2003) Chair opening remarks - The need for research linking discovery with development for manufacture; Overcoming the Challenges of Development and Manufacture. In: (Proceedings) SMI Linking Businesses with Information. : The Hilton, London, UK.

Hoare, M (2003) The EPSRC Innovative Manufacturing Research Centre (IMRC) for Bioprocessing - a multidisciplinary - multi-company partnership for research, training and technology transfer collaborations. In: (Proceedings) The Research Funding Paradox. : SCI, London, UK.

Hoare, M (2003) Using government support to build an industrial network - the EPSRC Innovative Manufacturing Research Centre for Bioprocessing, Evolving government support for university - industry interaction. In: (Proceedings) London Technology Network. : London Business School, UK.

Hoare, M and Willoughby, NA and Bracewell, DG and Baldascini, H and Booth, AB and Ngiam, SH and King, J (2003) Novel scale-down techniques in bioprocess operations. Applications of miniaturization techniques in development and validation of processes for manufacture of advanced biopharmaceuticals. In: (Proceedings) European Federation of Biotechnology. : London, UK.

Hussain, HA and Ward, JA (2003) Ferredoxin reductase enhances heterologously expressed cytochrome CYP105D1 in Escherichia coli and Streptomyces lividans. ENZYME MICROB TECH , 32 (7) 790 - 800. 10.1016/S0141-0229(03)00047-4.

Hussain, HA and Ward, JM (2003) Enhanced heterologous expression of two Streptomyces griseolus cytochrome P450s and Streptomyces coelicolor ferredoxin reductase as potentially efficient hydroxylation catalysts. APPL ENVIRON MICROB , 69 (1) 373 - 382. 10.1128/AEM.69.1.373-382.2003.

Hutchinson, N and Hoare, M (2003) Shear stress analysis for the prediction of industrial centrifugal clarification. In: (Proceedings) Recovery of Biological Products XI. : Banff, Canada.

I

Ingram, CU and Dalby, PA and Hailes, HC and Lye, GJ and Ward, J (2003) Engineering and directed evolution of multi-step biocatalytic pathways in bacteria. In: (Proceedings) 11th European Congress on Biotechnology. : Basel, Switzerland.

Ingram, CU and Dalby, PA and Hailes, HC and Lye, GJ and Ward, J (2003) Engineering and directed evolution of multi-step biocatalytic pathways in bacteria. In: (Proceedings) Enzyme Engineering XVII. : Santa Fe, New Mexico, USA.

Irvine, H and Zhou, Y and Baganz, F and Ward, J (2003) Antisense RNA: A metabolic engineering tool used to study overflow metabolism in Escherichia coli. In: (Proceedings) 1st IECA conference on Systems Biology of Escherichia Coli. : Tsuruoka, Japan.

J

Jaques, C and Baganz, F and Krabben, P and Ward, J and Zhou, Y (2003) Investigation of the causes of organic acid production during stationary phase in Saccharopolyspora erythraea using an uncoupler of oxidative phosphorylation. In: (Proceedings) BBSRC Streptomyces Dissemination Meeting. : University of Surrey, Guildford, UK.

Jenkins, R.G. and Meng, Q.-H. and Hodges, R.J. and Lee, L.K. and Bottoms, S.E.W. and Laurent, G.J. and Willis, D. and Shamlou, P.A. and McAnulty, R.J. and Hart, S.L. (2003) Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo. Gene Therapy , 10 (12) pp. 1026-1034. 10.1038/sj.gt.3301963.

Jenkins, R.G. and Meng, Q.-H. and Hodges, R.J. and Lee, L.K. and Bottoms, S.E.W. and Laurent, G.J. and Willis, D. and Shamlou, P.A. and McAnulty, R.J. and Hart, S.L. (2003) Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo. Gene Therapy , 10 (12) pp. 1026-1034. 10.1038/sj.gt.3301963.

K

Kay, A and O'Kennedy, R and Ward, J and Keshavarz-Moore, E (2003) Impact of plasmid size on cellular oxygen demand in Escherichia coli. BIOTECHNOL APPL BIOC , 38 1 - 7.

Keshavarz-Moore, E and Keshavarz, T (2003) Process comparison between production of antibody fragments in E.Coli and Aspergillus awamori. In: (Proceedings) 6th Italian Conference on Chemical and Process Engineering (ICHEAP - 6). : Pisa, Italy.

L

Lamping, S and Zhang, H and Allan, B and Shamlou, PA (2003) Design of a prototype miniature bioreactor for high throughput automated bioprocessing. Chemical Engineering Science , 58 747 - 758.

Lim, AC and Farid, S and Washbrook, J and Titchener-Hooker, NJ (2003) A structured decisional-support tool for rapid bioprocess modelling. In: (Proceedings) 225th American Chemical Society National meeting. : New Orleans, Louisiana, March 23-27.

Lim, AC and Farid, S and Washbrook, J and Titchener-Hooker, NJ (2003) Structured decisional-support tool for rapid bioprocess modelling. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. (pp. U216 - U216). AMER CHEMICAL SOC

Lim, AC and Farid, S and Washbrook, J and Titchener-Hooker, NJ (2003) The use of a modelling tool to quantify risks and uncertainty in the biomanufacturing industry. In: (Proceedings) 11th European Congress on Biotechnology. : Basel, Switzerland, August 24-29.

Lim, AC and Farid, S and Washbrook, J and Titchener-Hooker, NJ (2003) A tool for modelling the impact of regulatory compliance activities on the biomanufacturing industry. In: Kraslawski, A and Turunen, I, (eds.) EUROPEAN SYMPOSIUM ON COMPUTER AIDED PROCESS ENGINEERING - 13. (pp. 1109 - 1114). ELSEVIER SCIENCE BV

Loftian, P and Levy, MS and Coffin, RS and Ward, JM and Shamlou, PA (2003) Shear- induced release of disabled herpes simplex virus from BHK cells. Biotechnology and Applied Biochemistry , 38 271 - 281.

Lotfian, P and Levy, MS and Coffin, R and Ward, J and Shamlou, PA (2003) Shear-induced release of disabled herpes simplex virus from baby-hamster kidney cells. BIOTECHNOL APPL BIOC , 38 271 - 281. 10.1042/BA20030074.

Lye, GJ (2003) Automated microscale bioprocessing for the parallel evaluation of biocatalyst and process options. In: (Proceedings) Biochemical Engineering XII. : Boulder, Colorado, USA.

Lye, GJ (2003) Microscale process evaluation of evolved and metabolically engineered biocatalysts. In: (Proceedings) European Federation of Biotechnology meeting. : London.

Lye, GJ (2003) Training at the academia - industry and engineering - biology interfaces: A European university perspective. In: (Proceedings) Recovery of Biological Products XI. : Banff, Canada.

Lye, GJ and Ayazi-Shamlou, P and Baganz, F and Dalby, PA and Woodley, JM (2003) Accelerated design of bioconversion processes using automated microscale processing techniques. TRENDS BIOTECHNOL , 21 (1) 29 - 37.

M

Maguire, LA and Zhang, H and Shamlou, PA (2003) Preparation of small unilamellar vesicles (SUV) and biophysical characterization of their complexes with poly-l-lysine-condensed plasmid DNA. Biotechnology and Applied Biochemistry , 37 73 - 81.

Mason, C (2003) Automated tissue engineering: a major paradigm shift in health care. Med Device Technol , 14 (1) 16 - 18.

Mason, C (2003) Automated tissue engineering: A major paradigm shift in healthcare. Medical Device Technology , 14 (1) 16 - 18.

Mason, C (2003) How to tissue engineer. Biotechnology Investment Today , 2 (1) 25 - 25.

Mason, C (2003) The age of regenerative medicine. BioCommerce Data’s Biotechnology Compendium 1 - 3.

Mason, C (2003) The future lies in automation. Biotechnology Investment Today , 2 (1) 26 - 27.

Mason, C (2003) Tissue Engineering. Biotechnology Investment Today , 2 (1) 20 - 26.

Mason, C (2003) Why all the interest in tissue-engineered blood vessel? Biotechnology Investment Today , 2 (1) 22 - 23.

Mason, C and Markusen, JF and Boshoff, CH (2003) Methods employing cells derived from adult bone marrow.

Mason, C and Town, MA (2003) Delivery assembly for use in surgery.

Mason, C and Town, MA (2003) Devices for use in medicine. PCT/GB03/01334.

Micheletti, M and Nikiforaki, L and Kalok, KC and Yianneskis, M (2003) Particle concentration and mixing characteristics of moderate-to-dense solid-liquid suspensions. Ind. Eng. Chem. Res. , 42 6236 - 6249. 10.1021/ie0303799.

Mustafa, MA and Washbrook, J and Farid, S and Lim, AC and Titchener-Hooker, N (2003) Novel software tools for evaluating integration within a downstream process - A case study of expanded bed adsorption vs packed bed adsorption. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. (pp. U198 - U198). AMER CHEMICAL SOC

Mustafa, MA and Washbrook, J and Farid, S and Lim, J and Titchener-Hooker, NJ (2003) Novel software tools for business-process assessment of downstream processing options. In: (Proceedings) 11th European Congress on Biotechnology. : Basel, Switzerland, August 24-29.

Mustafa, MA and Washbrook, J and Lim, J and Farid, S and Titchener-Hooker, NJ (2003) Novel software tools for evaluating integration within a downstream process: A case study of expanded-bed adsorption vs. packed-bed adsorption. In: (Proceedings) 225th American Chemical Society National meeting. : New Orleans, Louisiana, March 23-27.

N

Neal, G and Christie, J and Keshavarz-Moore, E and Shamlou, PA (2003) Ultra scale-down approach for the prediction of full-scale recovery of ovine polycolonal immunoglobulins used in the manufacture of snake venom-specific Fab fragment. Biotechnology and Bioengineering , 81 (2) 149 - 157. 10.1002/bit.10454.

Neal, G and Christie, J and Keshavarz-Moore, E and Shamlou, PA (2003) Ultra scale-down approach for the prediction of full-scale recovery of ovine polycolonal immunoglobulins used in the manufacture of snake venom-specific Fab fragment. BIOTECHNOL BIOENG , 81 (2) 149 - 157. 10.1002/bit.10454.

Ngiam, SH and Bracewell, DG and Zhou, YH and Titchener-Hooker, NJ (2003) Quantifying process tradeoffs in the operation of chromatographic sequences. BIOTECHNOL PROGR , 19 (4) 1315 - 1322. 10.1021/bp034039u.

O

O'Kennedy, RD and Ward, JM and Keshavarz-Moore, E (2003) Effects of fermentation strategy on the characteristics of plasmid DNA production. BIOTECHNOL APPL BIOC , 37 83 - 90.

P

Peacock, L and Ward, J and Ratledge, C and Dickinson, FM and Ison, A (2003) How Streptomyces lividans uses oils and sugars as mixed substrates. ENZYME MICROB TECH , 32 (1) 157 - 166.

Poslethwaite, J and Leach, G and Hurwitz, M and Lye, GJ (2003) Design and optimisation of a vibrating membrane filtration process using response surface methodology. In: (Proceedings) Recovery of Biological Products XI. : Banff, Canada.

R

Reynolds, T and Boychyn, M and Sanderson, T and Bulmer, M and More, J and Hoare, M (2003) Scale-down of continuous filtration for rapid bioprocess design: Recovery and dewatering of protein precipitate suspensions. BIOTECHNOL BIOENG , 83 (4) 454 - 464. 10.1002/bit.10687.

Reynolds, TS and Boychyn, RM and Bulmer, M and More, J and Hoare, M (2003) Scale-down of continuous filtration for rapid bioprocess design. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. (pp. U230 - U230). AMER CHEMICAL SOC

Rock, C and Kohl, S and Ward, J and Levy, MS (2003) Plasmid processing for gene therapy and DNA vaccination: effect of centrifugation and resuspension of bacterial cells. Biotechnology Progress (Nucleic Acids Technology edition)

S

Sarkar, S and Zhang, H and Levy, MS and Hart, SL and Hales, HC and Tabor, AB and Shamlou, PA (2003) Prediction of size distribution of lipid-peptide DNA vector particles using Monte-Carlo simulation techniques. Biotechnology and Applied Biochemistry , 38 95 - 102.

Shaeri, J and Rathbone, EB and Wright, I and Wohlgemouth, R and Woodley, JM (2003) Multi-enzymatic synthesis of xylulose 5-phosphate. In: (Proceedings) 225th ACS National Meeting. : New Orleans, LA, USA.

Shimzu, M and Lilly, MD and Woodley, JM (2003) Regiospecific naphthalene monohydroxylation by a recombinant yeast producing a P4501A1-yeast reductase fused enzyme. Enzyme and Microbial Technology , 33 606 - 611.

Stephens, P and Wall, IB and Wilson, MJ and Hill, KE and Davies, CE and Hill, CM and Harding, KG and Thomas, DW (2003) Anaerobic cocci populating the deep tissues of chronic wounds impair cellular wound healing responses in vitro. BRIT J DERMATOL , 148 (3) 456 - 466.

T

Tait, AS and Brown, C and Galbraith, DJ and Hines, M and Hoare, M and Birch, J and James, DC (2003) Transient production of recombinant proteins by chinese hamster ovary cells using polyethyleneimine / DNA complexes in combination with microtubule disrupting anti-mitotic agents. In: (Proceedings) Cell Engineering Conference. : Cancun.

Tait, AS and Hoare, M and Birch, J and Galbraith, DJ and Hines, M and Brown, C and James, D (2003) Factors influencing scale-up of polyethlyleneimine mediated transient gene expression in CHO cells. In: (Proceedings) Fermentation and Bioprocess Interest Group Conference. : Sydney, Australia.

Teoh, HK and S rensen, E and Titchener-Hooker, N (2003) Optimal operating policies for closed loop recycling HPLC processes. Chemical Engineering Science , 58 (18) 4145 - 4158.

Teoh, HK and Sorensen, E and Titchener-Hooker, N (2003) Optimal operating policies for closed-loop recycling HPLC processes. CHEM ENG SCI , 58 (18) 4145 - 4158. 10.1016/S0009-2509(03)00287-2.

Teoh, HK and Sorensen, E and Titchener-Hooker, NJ (2003) Optimal operating policies for closed-loop recycling HPLC processes. Chemical Engineering Science , 58 4145 - 4158.

Titchener-Hooker, NJ and Hoare, M (2003) Engineering approaches to fast process development. In: (Proceedings) Biotech Manufacturing. : Amsterdam, Holland.

U

Uzir, MH and Woodley, JM (2003) Kinetic studies and parameter estimation of a modelled enzyme catalysed Baeyer - Villiger reaction. In: (Proceedings) 11th European Congress on Biotechnology. : Basel, Switzerland.

W

Ward, J and Baganz, F and Krabben, P and Fell, D and Poolman, M and Leadley, P (2003) Connecting Genome to Process: the linkage of Saccharopolyspora erythraea metaolic engineering to product flux. In: (Proceedings) BBSRC Grantholders Workshop: Exploiting genomics and Investigating Fene Function. : Carden Park.

Whitcher, CS and Littlechild, JA and Wohlgemouth, R and Woodley, JM (2003) Application of a Baeyer-Villiger monooxygenase from Cunninghamella echinulata NRRL 3655. In: (Proceedings) 225th ACS National Meeting. : New Orleans, LA, USA.

Willoughby, N and Martin, PL and Titchener-Hooker, NJ (2003) Ultra scale-down of expanded bed adsorption - purification of an antibody fragment directly from recombinant E.coli culture. In: (Proceedings) Recovery of Biological Products XI. : Banff, Canada.

Wilson, JA and Poslethwaite, J and Pearce, JD and Leach, G and Lye, GJ and Shamlou, PA (2003) Vibrating membrane filtration for the recovery of insect killing nematodes. Biotechnology and Bioengineering , 83 235 - 240.

Wilson, JA and Postlethwaite, J and Pearce, JD and Leach, G and Lye, GJ and Shamlou, PA (2003) Vibrating membrane filtration for recovery and concentration of insect killing nematodes. BIOTECHNOL BIOENG , 83 (2) 235 - 240. 10.1002/bit.10665.

Z

Zhang, H and Lamping, S and Allan, B and Shamlou, PA (2003) UNSPECIFIED In: (Proceedings) CFD simulation of the engineering flow environment in shaken micro-well plates. : Italy.

Zhou, Y and Griffiths, P and Titchener-Hooker, NJ (2003) Bioprocess robustness study for improving bioprocess validation. In: (Proceedings) 11th European Congress on Biotechnology. : Basel, Switzerland.

Zhou, Y and Titchener-Hooker, NJ (2003) The application of a Pareto optimisation method in the design of an integrated bioprocess. Bioprocess and Biosystems Engineering , 25 (6) 349 - 355. 10.1007/s00449-003-0318-0.

Zhou, YH and Titchener-Hooker, NJ (2003) The application of a Pareto optimisation method in the design of an integrated bioprocess. BIOPROC BIOSYST ENG , 25 (6) 349 - 355. 10.1007/s00449-003-0318-0.

Zoro, BJH and Drake, R and Hoare, M (2003) The design of automated process equipment for autologous blood vessel production. In: (Proceedings) BBSRC / EPSRC Tissue and Biochemical Engineering and Stem Cell Workshop. : Manchester Business School, Manchester, UK.

This list was generated on Tue Jun 18 08:47:10 2013 BST.