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Number of items: 99.

A

Ahmed, F; Lye, GJ; Woodley, JM; (2003) Tool for the rapid evaluation of process limitation using microscale experimention. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. (pp. U218 - U219). AMER CHEMICAL SOC

Ahmed, F; Lye, GJ; Woodley, JM; (2003) Tools for the rapid evaluation of process limitations using microscale experimentation. In: (Proceedings) 225th ACS National Meeting. : New Orleans, LA, USA.

Akhtar, MK; Kaderbhai, NN; Hopper, DJ; Kelly, SL; Kaderbhai, MA; (2003) Export of a Heterologous Cytochrome P450 (CYP105D1) in Escherichia coli Is Associated with Periplasmic Accumulation of Uroporphyrin. Journal of Biological Chemistry , 278 (46) 45555 - 45562. 10.1074/jbc.M212685200.

Alphand, V; Carrea, G; Wohlgemouth, R; Furstoss, R; Woodley, JM; (2003) Towards large-scale synthetic applications of Baeyer-Villiger monooxygenases. Trends in Biotechnology , 21 318 - 323.

Amanullah, A; Hewitt, CJ; Nienow, AW; Lee, C; Chartrain, M; Buckland, BC; ... Woodley, JM; + view all (2003) Measurement of strain-dependent toxicity in the indene bioconversion using multiparameter flow cytometry. Biotechnology and Bioengineering , 81 (4) 405 - 420.

B

Baldascini, H; Bracewell, DG; Hoare, M; (2003) Use of an ultra scale down device to predict degradation of biopharmaceuticals in recovery, purification and formulation operations. In: (Proceedings) 11th European Congress on Biotechnology, ECB 11. : Basel, Switzerland.

Baldwin, CF; Woodley, JM; (2003) Oxygen limitations in the biocatalytic BVMO catalysed synthesis of lactones. In: (Proceedings) 225th ACS National Meeting. : New Orleans, LA, USA.

Baldwin, CF; Woodley, JM; (2003) The role of oxygen limitation in the scale - up of biocatalytic BVMO catalysed synthesis of lactones. In: (Proceedings) 11th European Congress on Biotechnology. : Basel, Switzerland.

Baldwin, CF; Woodley, JM; (2003) Whole cell biocatalytic processes for selective oxidations by Baeyer-Villiger monooxygenases. In: (Proceedings) Interdisciplinary approaches to Industrial Biocatalysis: BioCat. : Barcelona, Spain.

Booth, AJ; Sutherland, IA; Lye, GJ; (2003) Modeling the performance of pilot-scale countercurrent chromatography: Scale-up predictions and experimental verification of erythromycin separation. BIOTECHNOL BIOENG , 81 (6) 640 - 649. 10.1002/bit.10508.

Bracewell, DG; Baldascini, H; Hoare, M; (2003) Innovation in scale-down methodology: integrating ultra scale-down devices, modelling and visualisation. In: (Proceedings) Bio CHC-03. : Boulder Colorado, USA.

Burton, SG; Cowan, DA; Woodley, JM; (2003) The ideal biocatalyst: The new approach and its application in biocatalysis process development. In: (Proceedings) 6th International Symposium on Biocatalysis and Biotransformations. : Olomouc, CZ.

C

Chan, S; S rensen, E; Titchener-Hooker, N; (2003) Optimal operation of simulated moving bed chromatographic processes. In: (Proceedings) Proceedings of ECCE'4, Granada, Spain.

Chan, S; Sorensen, E; Titchener-Hooker, N; (2003) Optimal operation of simulated moving bed chromatographic processes. In: (Proceedings) Proceedings of ECCE'4, Granada, Spain.

Cooke, GD; Cranenburgh, RM; Hanak, JAJ; Ward, JM; (2003) A modified Escherichia coli protein production strain expressing staphylococcal nuclease, capable of autohydrolysing host nucleic acid. J BIOTECHNOL , 101 (3) 229 - 239. 10.1016/S0168-1656(02)00339-5.

D

Dalby, PA; (2003) Optimising enzyme function by directed evolution. CURR OPIN STRUC BIOL , 13 (4) 500 - 505. 10.1016/S0959-440X(03)00101-5.

Dalby, PA; Aucamp, JP; (2003) Dialysis Apparatus.

Doig, SD; Simpson, H; Alphand, V; Furstoss, R; Woodley, JM; (2003) Characterisation of a recombinant Escherichia coli TOP10 (pQR239) whole-cell biocatalyst for stereoselective Baeyer-Villiger oxidations. Enzyme and Microbial Technology , 32 (3-4) 347 - 355.

Dunnill, P; Titchener-Hooker, NJ; Hoare, M; (2003) A method and apparatus for producing a biomaterial product. GB2364.

E

Elmahdi, I; Baganz, F; Dixon, K; Harrop, T; Sugden, D; Lye, GJ; (2003) Fermentation process optimisation via microwell fermentation with automated pH control. In: (Proceedings) Biochemical Engineering XII. : Boulder Colorado, USA.

Elmahdi, I; Baganz, F; Dixon, K; Harrop, T; Sugden, D; Lye, GJ; (2003) pH control in microwell fermentations of S-erythraea CA340: influence on biomass growth kinetics and erythromycin biosynthesis. BIOCHEM ENG J , 16 (3) 299 - 310. 10.1016/S1369-703X(03)00073-1.

H

Henderson, B; Nair, SP; Ward, JM; Wilson, M; (2003) Molecular pathogenicity of the oral opportunistic pathogen Actinobacillus actinomycetemcomitans. ANNU REV MICROBIOL , 57 29 - 55. 10.1146/annurev.micro.57.030502.090908.

Hernandez, D; Addou, S; Lee, D; Orengo, C; Shephard, EA; Phillips, IR; (2003) Trimethylaminuria and a human FMO3 mutation database. HUM MUTAT , 22 (3) 209 - 213. 10.1002/humu.10252.

Hoare, M; (2003) Chair opening remarks - The need for research linking discovery with development for manufacture; Overcoming the Challenges of Development and Manufacture. In: (Proceedings) SMI Linking Businesses with Information. : The Hilton, London, UK.

Hoare, M; (2003) The EPSRC Innovative Manufacturing Research Centre (IMRC) for Bioprocessing - a multidisciplinary - multi-company partnership for research, training and technology transfer collaborations. In: (Proceedings) The Research Funding Paradox. : SCI, London, UK.

Hoare, M; (2003) Using government support to build an industrial network - the EPSRC Innovative Manufacturing Research Centre for Bioprocessing, Evolving government support for university - industry interaction. In: (Proceedings) London Technology Network. : London Business School, UK.

Hoare, M; Willoughby, NA; Bracewell, DG; Baldascini, H; Booth, AB; Ngiam, SH; King, J; (2003) Novel scale-down techniques in bioprocess operations. Applications of miniaturization techniques in development and validation of processes for manufacture of advanced biopharmaceuticals. In: (Proceedings) European Federation of Biotechnology. : London, UK.

Hussain, HA; Ward, JA; (2003) Ferredoxin reductase enhances heterologously expressed cytochrome CYP105D1 in Escherichia coli and Streptomyces lividans. ENZYME MICROB TECH , 32 (7) 790 - 800. 10.1016/S0141-0229(03)00047-4.

Hussain, HA; Ward, JM; (2003) Enhanced heterologous expression of two Streptomyces griseolus cytochrome P450s and Streptomyces coelicolor ferredoxin reductase as potentially efficient hydroxylation catalysts. APPL ENVIRON MICROB , 69 (1) 373 - 382. 10.1128/AEM.69.1.373-382.2003.

Hutchinson, N; Hoare, M; (2003) Shear stress analysis for the prediction of industrial centrifugal clarification. In: (Proceedings) Recovery of Biological Products XI. : Banff, Canada.

I

Ingram, CU; Dalby, PA; Hailes, HC; Lye, GJ; Ward, J; (2003) Engineering and directed evolution of multi-step biocatalytic pathways in bacteria. In: (Proceedings) 11th European Congress on Biotechnology. : Basel, Switzerland.

Ingram, CU; Dalby, PA; Hailes, HC; Lye, GJ; Ward, J; (2003) Engineering and directed evolution of multi-step biocatalytic pathways in bacteria. In: (Proceedings) Enzyme Engineering XVII. : Santa Fe, New Mexico, USA.

Irvine, H; Zhou, Y; Baganz, F; Ward, J; (2003) Antisense RNA: A metabolic engineering tool used to study overflow metabolism in Escherichia coli. In: (Proceedings) 1st IECA conference on Systems Biology of Escherichia Coli. : Tsuruoka, Japan.

J

Jaques, C; Baganz, F; Krabben, P; Ward, J; Zhou, Y; (2003) Investigation of the causes of organic acid production during stationary phase in Saccharopolyspora erythraea using an uncoupler of oxidative phosphorylation. In: (Proceedings) BBSRC Streptomyces Dissemination Meeting. : University of Surrey, Guildford, UK.

Jenkins, R.G.; Meng, Q.-H.; Hodges, R.J.; Lee, L.K.; Bottoms, S.E.W.; Laurent, G.J.; ... Hart, S.L.; + view all (2003) Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo. Gene Therapy , 10 (12) pp. 1026-1034. 10.1038/sj.gt.3301963.

Jenkins, R.G.; Meng, Q.-H.; Hodges, R.J.; Lee, L.K.; Bottoms, S.E.W.; Laurent, G.J.; ... Hart, S.L.; + view all (2003) Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo. Gene Therapy , 10 (12) pp. 1026-1034. 10.1038/sj.gt.3301963.

K

Kaderbhai, MA; Hopper, DJ; Akhtar, KM; Abbas, SK; Kaderbhai, NN; (2003) A cytochrome c from a lupanine-transforming Pseudomonas putida strain is expressed in Escherichia coli during aerobic cultivation and efficiently exported and assembled in the periplasm. Applied and Environmental Microbiology , 69 (8) 4727 - 4731. 10.1128/AEM.69.8.4727-4731.2003.

Kay, A; O'Kennedy, R; Ward, J; Keshavarz-Moore, E; (2003) Impact of plasmid size on cellular oxygen demand in Escherichia coli. BIOTECHNOL APPL BIOC , 38 1 - 7.

Keshavarz-Moore, E; Keshavarz, T; (2003) Process comparison between production of antibody fragments in E.Coli and Aspergillus awamori. In: (Proceedings) 6th Italian Conference on Chemical and Process Engineering (ICHEAP - 6). : Pisa, Italy.

L

Lamping, S; Zhang, H; Allan, B; Shamlou, PA; (2003) Design of a prototype miniature bioreactor for high throughput automated bioprocessing. Chemical Engineering Science , 58 747 - 758.

Lim, AC; Farid, S; Washbrook, J; Titchener-Hooker, NJ; (2003) A structured decisional-support tool for rapid bioprocess modelling. In: (Proceedings) 225th American Chemical Society National meeting. : New Orleans, Louisiana, March 23-27.

Lim, AC; Farid, S; Washbrook, J; Titchener-Hooker, NJ; (2003) Structured decisional-support tool for rapid bioprocess modelling. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. (pp. U216 - U216). AMER CHEMICAL SOC

Lim, AC; Farid, S; Washbrook, J; Titchener-Hooker, NJ; (2003) The use of a modelling tool to quantify risks and uncertainty in the biomanufacturing industry. In: (Proceedings) 11th European Congress on Biotechnology. : Basel, Switzerland, August 24-29.

Lim, AC; Farid, S; Washbrook, J; Titchener-Hooker, NJ; (2003) A tool for modelling the impact of regulatory compliance activities on the biomanufacturing industry. In: Kraslawski, A and Turunen, I, (eds.) EUROPEAN SYMPOSIUM ON COMPUTER AIDED PROCESS ENGINEERING - 13. (pp. 1109 - 1114). ELSEVIER SCIENCE BV

Loftian, P; Levy, MS; Coffin, RS; Ward, JM; Shamlou, PA; (2003) Shear- induced release of disabled herpes simplex virus from BHK cells. Biotechnology and Applied Biochemistry , 38 271 - 281.

Lotfian, P; Levy, MS; Coffin, R; Ward, J; Shamlou, PA; (2003) Shear-induced release of disabled herpes simplex virus from baby-hamster kidney cells. BIOTECHNOL APPL BIOC , 38 271 - 281. 10.1042/BA20030074.

Lye, GJ; (2003) Automated microscale bioprocessing for the parallel evaluation of biocatalyst and process options. In: (Proceedings) Biochemical Engineering XII. : Boulder, Colorado, USA.

Lye, GJ; (2003) Microscale process evaluation of evolved and metabolically engineered biocatalysts. In: (Proceedings) European Federation of Biotechnology meeting. : London.

Lye, GJ; (2003) Training at the academia - industry and engineering - biology interfaces: A European university perspective. In: (Proceedings) Recovery of Biological Products XI. : Banff, Canada.

Lye, GJ; Ayazi-Shamlou, P; Baganz, F; Dalby, PA; Woodley, JM; (2003) Accelerated design of bioconversion processes using automated microscale processing techniques. TRENDS BIOTECHNOL , 21 (1) 29 - 37.

M

Maguire, LA; Zhang, H; Shamlou, PA; (2003) Preparation of small unilamellar vesicles (SUV) and biophysical characterization of their complexes with poly-l-lysine-condensed plasmid DNA. Biotechnology and Applied Biochemistry , 37 73 - 81.

Mason, C; (2003) Automated tissue engineering: a major paradigm shift in health care. Med Device Technol , 14 (1) 16 - 18.

Mason, C; (2003) Automated tissue engineering: A major paradigm shift in healthcare. Medical Device Technology , 14 (1) 16 - 18.

Mason, C; (2003) How to tissue engineer. Biotechnology Investment Today , 2 (1) 25 - 25.

Mason, C; (2003) The age of regenerative medicine. BioCommerce Data’s Biotechnology Compendium 1 - 3.

Mason, C; (2003) The future lies in automation. Biotechnology Investment Today , 2 (1) 26 - 27.

Mason, C; (2003) Tissue Engineering. Biotechnology Investment Today , 2 (1) 20 - 26.

Mason, C; (2003) Why all the interest in tissue-engineered blood vessel? Biotechnology Investment Today , 2 (1) 22 - 23.

Mason, C; Markusen, JF; Boshoff, CH; (2003) Methods employing cells derived from adult bone marrow.

Mason, C; Town, MA; (2003) Delivery assembly for use in surgery.

Mason, C; Town, MA; (2003) Devices for use in medicine. PCT/GB03/01334.

Micheletti, M; Nikiforaki, L; Kalok, KC; Yianneskis, M; (2003) Particle concentration and mixing characteristics of moderate-to-dense solid-liquid suspensions. Ind. Eng. Chem. Res. , 42 6236 - 6249. 10.1021/ie0303799.

Mustafa, MA; Washbrook, J; Farid, S; Lim, AC; Titchener-Hooker, N; (2003) Novel software tools for evaluating integration within a downstream process - A case study of expanded bed adsorption vs packed bed adsorption. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. (pp. U198 - U198). AMER CHEMICAL SOC

Mustafa, MA; Washbrook, J; Farid, S; Lim, J; Titchener-Hooker, NJ; (2003) Novel software tools for business-process assessment of downstream processing options. In: (Proceedings) 11th European Congress on Biotechnology. : Basel, Switzerland, August 24-29.

Mustafa, MA; Washbrook, J; Lim, J; Farid, S; Titchener-Hooker, NJ; (2003) Novel software tools for evaluating integration within a downstream process: A case study of expanded-bed adsorption vs. packed-bed adsorption. In: (Proceedings) 225th American Chemical Society National meeting. : New Orleans, Louisiana, March 23-27.

N

Neal, G; Christie, J; Keshavarz-Moore, E; Shamlou, PA; (2003) Ultra scale-down approach for the prediction of full-scale recovery of ovine polycolonal immunoglobulins used in the manufacture of snake venom-specific Fab fragment. Biotechnology and Bioengineering , 81 (2) 149 - 157. 10.1002/bit.10454.

Neal, G; Christie, J; Keshavarz-Moore, E; Shamlou, PA; (2003) Ultra scale-down approach for the prediction of full-scale recovery of ovine polycolonal immunoglobulins used in the manufacture of snake venom-specific Fab fragment. BIOTECHNOL BIOENG , 81 (2) 149 - 157. 10.1002/bit.10454.

Ngiam, SH; Bracewell, DG; Zhou, YH; Titchener-Hooker, NJ; (2003) Quantifying process tradeoffs in the operation of chromatographic sequences. BIOTECHNOL PROGR , 19 (4) 1315 - 1322. 10.1021/bp034039u.

O

O'Kennedy, RD; Ward, JM; Keshavarz-Moore, E; (2003) Effects of fermentation strategy on the characteristics of plasmid DNA production. BIOTECHNOL APPL BIOC , 37 83 - 90.

P

Peacock, L; Ward, J; Ratledge, C; Dickinson, FM; Ison, A; (2003) How Streptomyces lividans uses oils and sugars as mixed substrates. ENZYME MICROB TECH , 32 (1) 157 - 166.

Poslethwaite, J; Leach, G; Hurwitz, M; Lye, GJ; (2003) Design and optimisation of a vibrating membrane filtration process using response surface methodology. In: (Proceedings) Recovery of Biological Products XI. : Banff, Canada.

R

Rathore, A; Velayudhan, A; (2003) Guidelines for optimization and scale-up in preparative chromatography. BioPharm International , 16 (1) 34 - 42.

Rathore, A; Velayudhan, A; (2003) Guidelines for optimization and scale-up in preparative chromatography. BioPharm International , 16 (1) 34 - 42.

Rathore, A; Velayudhan, A; (2003) Scale-Up and Optimization in Preparative Chromatography. Chromatographic Science Series. Marcel Dekker, Inc.: New York, US.

Reynolds, T; Boychyn, M; Sanderson, T; Bulmer, M; More, J; Hoare, M; (2003) Scale-down of continuous filtration for rapid bioprocess design: Recovery and dewatering of protein precipitate suspensions. BIOTECHNOL BIOENG , 83 (4) 454 - 464. 10.1002/bit.10687.

Reynolds, TS; Boychyn, RM; Bulmer, M; More, J; Hoare, M; (2003) Scale-down of continuous filtration for rapid bioprocess design. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. (pp. U230 - U230). AMER CHEMICAL SOC

Rock, C; Kohl, S; Ward, J; Levy, MS; (2003) Plasmid processing for gene therapy and DNA vaccination: effect of centrifugation and resuspension of bacterial cells. Biotechnology Progress (Nucleic Acids Technology edition)

S

Sarkar, S; Zhang, H; Levy, MS; Hart, SL; Hales, HC; Tabor, AB; Shamlou, PA; (2003) Prediction of size distribution of lipid-peptide DNA vector particles using Monte-Carlo simulation techniques. Biotechnology and Applied Biochemistry , 38 95 - 102.

Shaeri, J; Rathbone, EB; Wright, I; Wohlgemouth, R; Woodley, JM; (2003) Multi-enzymatic synthesis of xylulose 5-phosphate. In: (Proceedings) 225th ACS National Meeting. : New Orleans, LA, USA.

Shimzu, M; Lilly, MD; Woodley, JM; (2003) Regiospecific naphthalene monohydroxylation by a recombinant yeast producing a P4501A1-yeast reductase fused enzyme. Enzyme and Microbial Technology , 33 606 - 611.

Stephens, P; Wall, IB; Wilson, MJ; Hill, KE; Davies, CE; Hill, CM; ... Thomas, DW; + view all (2003) Anaerobic cocci populating the deep tissues of chronic wounds impair cellular wound healing responses in vitro. BRIT J DERMATOL , 148 (3) 456 - 466.

T

Tait, AS; Brown, C; Galbraith, DJ; Hines, M; Hoare, M; Birch, J; James, DC; (2003) Transient production of recombinant proteins by chinese hamster ovary cells using polyethyleneimine / DNA complexes in combination with microtubule disrupting anti-mitotic agents. In: (Proceedings) Cell Engineering Conference. : Cancun.

Tait, AS; Hoare, M; Birch, J; Galbraith, DJ; Hines, M; Brown, C; James, D; (2003) Factors influencing scale-up of polyethlyleneimine mediated transient gene expression in CHO cells. In: (Proceedings) Fermentation and Bioprocess Interest Group Conference. : Sydney, Australia.

Teoh, HK; S rensen, E; Titchener-Hooker, N; (2003) Optimal operating policies for closed loop recycling HPLC processes. Chemical Engineering Science , 58 (18) 4145 - 4158.

Teoh, HK; Sorensen, E; Titchener-Hooker, N; (2003) Optimal operating policies for closed-loop recycling HPLC processes. CHEM ENG SCI , 58 (18) 4145 - 4158. 10.1016/S0009-2509(03)00287-2.

Teoh, HK; Sorensen, E; Titchener-Hooker, NJ; (2003) Optimal operating policies for closed-loop recycling HPLC processes. Chemical Engineering Science , 58 4145 - 4158.

Titchener-Hooker, NJ; Hoare, M; (2003) Engineering approaches to fast process development. In: (Proceedings) Biotech Manufacturing. : Amsterdam, Holland.

U

Uzir, MH; Woodley, JM; (2003) Kinetic studies and parameter estimation of a modelled enzyme catalysed Baeyer - Villiger reaction. In: (Proceedings) 11th European Congress on Biotechnology. : Basel, Switzerland.

W

Wall, I; Rennison, T; Thomas, DW; Stephens, P; (2003) Modulation of bacterially inhibited cellular wound healing responses by Actisorb Silver 220. In: Wound Repair Regen. (pp. A45 - A45).

Ward, J; Baganz, F; Krabben, P; Fell, D; Poolman, M; Leadley, P; (2003) Connecting Genome to Process: the linkage of Saccharopolyspora erythraea metaolic engineering to product flux. In: (Proceedings) BBSRC Grantholders Workshop: Exploiting genomics and Investigating Fene Function. : Carden Park.

Whitcher, CS; Littlechild, JA; Wohlgemouth, R; Woodley, JM; (2003) Application of a Baeyer-Villiger monooxygenase from Cunninghamella echinulata NRRL 3655. In: (Proceedings) 225th ACS National Meeting. : New Orleans, LA, USA.

Willoughby, N; Martin, PL; Titchener-Hooker, NJ; (2003) Ultra scale-down of expanded bed adsorption - purification of an antibody fragment directly from recombinant E.coli culture. In: (Proceedings) Recovery of Biological Products XI. : Banff, Canada.

Wilson, JA; Poslethwaite, J; Pearce, JD; Leach, G; Lye, GJ; Shamlou, PA; (2003) Vibrating membrane filtration for the recovery of insect killing nematodes. Biotechnology and Bioengineering , 83 235 - 240.

Wilson, JA; Postlethwaite, J; Pearce, JD; Leach, G; Lye, GJ; Shamlou, PA; (2003) Vibrating membrane filtration for recovery and concentration of insect killing nematodes. BIOTECHNOL BIOENG , 83 (2) 235 - 240. 10.1002/bit.10665.

Z

Zhang, H; Lamping, S; Allan, B; Shamlou, PA; (2003) UNSPECIFIED In: (Proceedings) CFD simulation of the engineering flow environment in shaken micro-well plates. : Italy.

Zhou, Y; Griffiths, P; Titchener-Hooker, NJ; (2003) Bioprocess robustness study for improving bioprocess validation. In: (Proceedings) 11th European Congress on Biotechnology. : Basel, Switzerland.

Zhou, Y; Titchener-Hooker, NJ; (2003) The application of a Pareto optimisation method in the design of an integrated bioprocess. Bioprocess and Biosystems Engineering , 25 (6) 349 - 355. 10.1007/s00449-003-0318-0.

Zhou, YH; Titchener-Hooker, NJ; (2003) The application of a Pareto optimisation method in the design of an integrated bioprocess. BIOPROC BIOSYST ENG , 25 (6) 349 - 355. 10.1007/s00449-003-0318-0.

Zoro, BJH; Drake, R; Hoare, M; (2003) The design of automated process equipment for autologous blood vessel production. In: (Proceedings) BBSRC / EPSRC Tissue and Biochemical Engineering and Stem Cell Workshop. : Manchester Business School, Manchester, UK.

This list was generated on Sun Jul 27 12:14:26 2014 BST.