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Number of items: 84.
A
| Abe, Y. (2011) The molecular basis for antibody stability in the bioprocess environment. Doctoral thesis, UCL (University College London). |
| Affandy, A and Versteeg, H and Keshavarz-Moore, E (2011) Investigation of causes of transmissions and topological changes of large plasmids in sterile filters. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. |
| Ahmad, S. (2011) Analysis of the precipitation and aggregation of engineered proteins. Doctoral thesis, UCL (University College London). |
| Ahmad, SS and Dalby, PA (2011) Thermodynamic Parameters for Salt-Induced Reversible Protein Precipitation From Automated Microscale Experiments. BIOTECHNOL BIOENG , 108 (2) 322 - 332. 10.1002/bit.22957. |
| Allmendinger, R and Knowles, J (2011) Evolutionary search in lethal environments. In: ECTA 2011 FCTA 2011 - Proceedings of the International Conference on Evolutionary Computation Theory and Applications and International Conference on Fuzzy Computation Theory and Applications. (pp. 63 - 72). |
| Allmendinger, R and Knowles, J (2011) Policy learning in resource-constrained optimization. In: Genetic and Evolutionary Computation Conference, GECCO'11. (pp. 1971 - 1978). |
B
| Balasundaram, B and Sachdeva, S and Bracewell, DG (2011) Dual Salt Precipitation for the Recovery of a Recombinant Protein from Escherichia coli. BIOTECHNOL PROGR , 27 (5) 1306 - 1314. 10.1002/btpr.645. |
| Bracewell, DG (2011) Enabling precipitation as an operation to manage critical contaminants in bioprocessing. In: (Proceedings) 10th Biological Production Forum. : 22 Jun 2011. |
| Bae, D.-K. (2011) Developing an efficient process for the production of retinal progenitor cells (RPCs) from human pluripotent stem cells using lowered oxygen tension. Doctoral thesis, UCL (University College London). |  |
| Beckett, P.J. (2011) Ultra scale-down of elution chromatography. Doctoral thesis, UCL (University College London). | |
| Berrill, A and Ho, SV and Bracewell, DG (2011) Mass Spectrometry to Describe Product and Contaminant Adsorption Properties for Bioprocess Development. BIOTECHNOL BIOENG , 108 (8) 1862 - 1871. 10.1002/bit.23115. |
| Blas, P. (2011) Ultra scale-down analysis and bioprocessing of fusion proteins. Doctoral thesis, UCL (University College London). |
| Boushaba, R and Baldascini, H and Gerontas, S and Titchener-Hooker, NJ and Bracewell, DG (2011) Demonstration of the Use of Windows of Operation to Visualize the Effects of Fouling on the Performance of a Chromatographic Step. BIOTECHNOL PROGR , 27 (4) 1009 - 1017. 10.1002/btpr.617. |
| Bracewell, DG and Berrill, A and Biddlecombe, J (2011) Product Quality During Manufacture and Supply. In: Walle, CVD, (ed.) Peptide and Protein Delivery. (313 - 339). Academic Press |
| Branston, S and Stanley, E and Ward, J and Keshavarz-Moore, E (2011) Study of Robustness of Filamentous Bacteriophages for Industrial Applications. BIOTECHNOL BIOENG , 108 (6) 1468 - 1472. 10.1002/bit.23066. |
| Branston, S and Stanley, E and Ward, J and Keshavarz-Moore, E (2011) Study of robustness of filamentous bacteriophages for industrial applications. Biotechnol Bioeng , 108 (6) 1468 - 1472. 10.1002/bit.23066. |
| Brindley, D and Moorthy, K and Lee, JH and Mason, C and Kim, HW and Wall, I (2011) Bioprocess forces and their impact on cell behavior: implications for bone regeneration therapy. J Tissue Eng , 2011 620247 - ?. 10.4061/2011/620247. |
| Brindley, DA and Reeve, BC and Sahlman, WA and Bonfiglio, GA and Davie, NL and Culme-Seymour, EJ and Mason, C (2011) The Impact of Market Volatility on the Cell Therapy Industry. CELL STEM CELL , 9 (5) 397 - 401. 10.1016/j.stem.2011.10.010. |
| Brown, A.I. (2011) An ultra scale-down approach to the rapid evaluation of pleated membrane cartridge filter performance. Doctoral thesis, UCL (University College London). | |
| Brown, AI and Titchener-Hooker, NJ and Lye, GJ (2011) Scale-Down Prediction of Industrial Scale Pleated Membrane Cartridge Performance. BIOTECHNOL BIOENG , 108 (4) 830 - 838. 10.1002/bit.23013. |
| Brown, AI and Titchener-Hooker, NJ and Lye, GJ (2011) Scale-down prediction of industrial scale pleated membrane cartridge performance. Biotechnol Bioeng , 108 (4) 830 - 838. 10.1002/bit.23013. |
C
| Chang, M.-W. (2011) Forming of novel drug carriers for stimulated encapsulation, storage and release. Doctoral thesis, UCL (University College London). |
| Chang, Y.-C. (2011) Practical investigation on the hydrodynamic behaviour of chromatographic columns packed with compressible media. Doctoral thesis, UCL (University College London). |
| Chhatre, S and Farid, SS and Coffman, J and Bird, P and Newcombe, AR and Titchener-Hooker, NJ (2011) How implementation of Quality by Design and advances in Biochemical Engineering are enabling efficient bioprocess development and manufacture. J CHEM TECHNOL BIOT , 86 (9) 1125 - 1129. 10.1002/jctb.2628. |
| Chhatre, S and Konstantinidis, S and Ji, Y and Edwards-Parton, S and Zhou, Y and Titchener-Hooker, NJ (2011) The simplex algorithm for the rapid identification of operating conditions during early bioprocess development: Case studies in FAb' precipitation and multimodal chromatography. Biotechnology and Bioengineering , 108 (9) 2162 - 2170. |
| Chhatre, S and Konstantinidis, S and Ji, Y and Edwards-Parton, S and Zhou, YH and Titchener-Hooker, NJ (2011) The Simplex Algorithm for the Rapid Identification of Operating Conditions During Early Bioprocess Development: Case Studies in FAb' Precipitation and Multimodal Chromatography. BIOTECHNOL BIOENG , 108 (9) 2162 - 2170. 10.1002/bit.23151. |
| Chhatre, S and Pampel, L and Titchener-Hooker, NJ (2011) Integrated Use of Ultra Scale-Down and Financial Modeling to Identify Optimal Conditions for the Precipitation and Centrifugal Recovery of Milk Proteins. BIOTECHNOL PROGR , 27 (4) 998 - 1008. 10.1002/btpr.612. |
D
| Dhanoya, A and Chain, BM and Keshavarz-Moore, E (2011) The impact of DNA topology on polyplex uptake and transfection efficiency in mammalian cells. J BIOTECHNOL , 155 (4) 377 - 386. 10.1016/j.jbiotec.2011.07.023. |
| Dalby, PA (2011) Strategy and success for the directed evolution of enzymes. CURR OPIN STRUC BIOL , 21 (4) 473 - 480. 10.1016/j.sbi.2011.05.003. |
| Dartnell, LR and Storrie-Lombardi, MC and Mullineaux, CW and Ruban, AV and Wright, G and Griffiths, AD and Muller, JP and Ward, JM (2011) Degradation of cyanobacterial biosignatures by ionizing radiation. Astrobiology , 11 (10) 997 - 1016. 10.1089/ast.2011.0663. |
| DeGrado, B and Dalby, P (2011) Engineering and Design. CURR OPIN STRUC BIOL , 21 (4) 450 - 451. 10.1016/j.sbi.2011.06.003. |
| Donos, N and Retzepi, M and Wall, I and Hamlet, S and Ivanovski, S (2011) In vivo gene expression profile of guided bone regeneration associated with a microrough titanium surface. CLIN ORAL IMPLAN RES , 22 (4) 390 - 398. 10.1111/j.1600-0501.2010.02105.x. |
| Dosanjh, J.K.S. (2011) Protein damage during purification: understanding the effects of size exclusion chromatography on the structure of biosynthetic human insulin (BHI). Doctoral thesis, UCL (University College London). |
F
| Fernandes, RL and Nierychlo, M and Lundin, L and Pedersen, AE and Puentes Tellez, PE and Dutta, A and Carlquist, M and Bolic, A and Schäpper, D and Brunetti, AC and Helmark, S and Heins, AL and Jensen, AD and Nopens, I and Rottwitt, K and Szita, N and van Elsas, JD and Nielsen, PH and Martinussen, J and Sørensen, SJ and Lantz, AE and Gernaey, KV (2011) Experimental methods and modeling techniques for description of cell population heterogeneity. Biotechnol Adv , 29 (6) 575 - 599. 10.1016/j.biotechadv.2011.03.007. |
G
| Grant, C and Woodley, JM and Baganz, F (2011) Whole-cell bio-oxidation of n-dodecane using the alkane hydroxylase system of P-putida GPo1 expressed in E-coil. ENZYME MICROB TECH , 48 (6-7) 480 - 486. 10.1016/j.enzmictec.2011.01.008. |
| Grant, Y.G. (2011) Engineering the rational design and optimisation of lyophilization processes for biological materials. Doctoral thesis, UCL (University College London). |
H
| Hardick, O and Stevens, B and Bracewell, DG (2011) Nanofibre fabrication in a temperature and humidity controlled environment for improved fibre consistency. J MATER SCI , 46 (11) 3890 - 3898. 10.1007/s10853-011-5310-5. |
| Hemsley, AL and Hernandez, D and Mason, C and Pelling, AE and Veraitch, FS (2011) Precisely delivered nano-mechanical forces induce blebbing in undifferentiated mouse embryonic stem cells. Cell Health and Cytoskeleton , 3 23 - 34. 10.2147/CHC.S13863. (In press). |
| Hemsley, AL and Hernandez, D and Mason, C and Pelling, AE and Veraitch, FS (2011) Precisely delivered nanomechanical forces induce blebbing in undifferentiated mouse embryonic stem cells. Cell Health and Cytoskeleton , 3 (1) 23 - 34. |
| Hernandez, D and Ruban, L and Mason, C (2011) Feeder-Free Culture of Human Embryonic Stem Cells for Scalable Expansion in a Reproducible Manner. STEM CELLS DEV , 20 (6) 1089 - 1098. 10.1089/scd.2009.0507. |
| Hudman, P.A. (2011) Investigation of recombinant protein production by Escherichia coli : expression of Green fluorescent protein and a co-factor dependent flavinated enzyme. Doctoral thesis, UCL (University College London). | |
| Hunter, SJ and Easton, S and Booth, V and Henderson, B and Wade, WG and Ward, JM (2011) Selective removal of human DNA from metagenomic DNA samples extracted from dental plaque. J BASIC MICROB , 51 (4) 442 - 446. 10.1002/jobm.201000372. |
I
| Ivanovski, S and Hamlet, S and Retzepi, M and Wall, I and Donos, N (2011) Transcriptional profiling of "guided bone regeneration" in a critical-size calvarial defect. CLIN ORAL IMPLAN RES , 22 (4) 382 - 389. 10.1111/j.1600-0501.2010.02104.x. |
J
| Jackson, N.B. (2011) Microscale approaches to the rapid evaluation and specification of microfiltration processes. Doctoral thesis, UCL (University College London). | |
| Jahromi, RRF and Morris, P and Martinez-Torres, RJ and Dalby, PA (2011) Structural stability of E. coli transketolase to temperature and pH denaturation. J BIOTECHNOL , 155 (2) 209 - 216. 10.1016/j.jbiotec.2011.06.023. |
K
| Knevelman, C.A. (2011) An evaluation of bioprocess development approaches for the precipitation-based purification of IgG monoclonal antibodies. Doctoral thesis, UCL (University College London). |
L
| Li, Q and Bai, Z and O'Donnell, A and Harvey, LM and Hoskisson, PA and McNeil, B (2011) Oxidative stress in fungal fermentation processes: the roles of alternative respiration. BIOTECHNOL LETT , 33 (3) 457 - 467. 10.1007/s10529-010-0471-x. |
| Lilley, R.E. (2011) Fundamental studies to design novel enzyme technologies for home and personal care applications. Doctoral thesis, UCL (University College London). |
| Looby, M and Ibarra, N and Pierce, JJ and Buckley, K and O'Donovan, E and Heenan, M and Moran, E and Farid, SS and Baganz, F (2011) Application of quality by design principles to the development and technology transfer of a major process improvement for the manufacture of a recombinant protein. Biotechnol Prog , 27 (6) 1718 - 1729. 10.1002/btpr.672. |
| Lye, G and Paul, D and Frank, B and John, W and Helen, H (2011) Biocatalysis is the future... The future is now! Chemical Engineer (839) 36 - 38. |
M
| Mahendrarajah, K and Dalby, PA and Wilkinson, B and Jackson, SE and Main, ERG (2011) A high-throughput fluorescence chemical denaturation assay as a general screen for protein-ligand binding. ANAL BIOCHEM , 411 (1) 155 - 157. 10.1016/j.ab.2010.12.001. |
| Mason, C (2011) Unnatural: The Heretical Idea of Making People. NATURE , 471 (7338) 297 - 298. |
| Mason, C and Brindley, DA and Culme-Seymour, EJ and Davie, NL (2011) Cell therapy industry: billion dollar global business with unlimited potential. Regen Med , 6 (3) 265 - 272. 10.2217/rme.11.28. |
| Matosevic, S and Lye, GJ and Baganz, F (2011) Immobilised enzyme microreactor for screening of multi-step bioconversions: Characterisation of a de novo transketolase-omega-transaminase pathway to synthesise chiral amino alcohols. J BIOTECHNOL , 155 (3) 320 - 329. 10.1016/j.jbiotec.2011.07.017. |
| Matosevic, S and Szita, N and Baganz, F (2011) Fundamentals and applications of immobilized microfluidic enzymatic reactors. J CHEM TECHNOL BIOT , 86 (3) 325 - 334. 10.1002/jctb.2564. |
| Melgarejo-Torres, R and Torres-Martinez, D and Gutierrez-Rojas, M and Gomez de Jesus, A and Lye, GJ and Huerta-Ochoa, S (2011) Regime analysis of a Baeyer-Villiger bioconversion in a three-phase (air-water-ionic liquid) stirred tank bioreactor. BIOCHEMICAL ENGINEERING JOURNAL , 58-59 87 - 95. 10.1016/j.bej.2011.08.017. |
| Mondragon-Teran, P and Baboo, JZ and Mason, C and Lye, GJ and Veraitch, FS (2011) The full spectrum of physiological oxygen tensions and step-changes in oxygen tension affects the neural differentiation of mouse embryonic stem cells. Biotechnology Progress , 27 (6) 1700 - 1708. |
| Mondragon-Teran, P and Baboo, JZ and Mason, C and Lye, GJ and Veraitch, FS (2011) The full spectrum of physiological oxygen tensions and step-changes in oxygen tension affects the neural differentiation of mouse embryonic stem cells. Biotechnol Prog , 27 (6) 1700 - 1708. 10.1002/btpr.675. |
| Moore, JD and Perez-Pardo, MA and Popplewell, JF and Spencer, SJ and Ray, S and Swann, MJ and Shard, AG and Jones, W and Hills, A and Bracewell, DG (2011) Chemical and biological characterisation of a sensor surface for bioprocess monitoring. BIOSENS BIOELECTRON , 26 (6) 2940 - 2947. 10.1016/j.bios.2010.11.043. |
| Mukhopadhyay, TK and Allison, N and Charlton, S and Ward, J and Lye, GJ (2011) Use of microwells to investigate the effect of quorum sensing on growth and antigen production in Bacillus anthracis Sterne 34F(2). J APPL MICROBIOL , 111 (5) 1224 - 1234. 10.1111/j.1365-2672.2011.05143.x. |
| Mulhall, H and Patel, M and Alqahtani, K and Mason, C and Lewis, MP and Wall, I (2011) Effect of capillary shear stress on recovery and osteogenic differentiation of muscle-derived precursor cell populations. J TISSUE ENG REGEN M , 5 (8) 629 - 635. 10.1002/term.355. |
O
| O'Callaghan, AR and Daniels, JT and Mason, C (2011) Effect of Sub-Atmospheric Oxygen on the Culture of Rabbit Limbal Epithelial Cells. In: CURR EYE RES. (pp. 691 - 698). INFORMA HEALTHCARE |
P
| Paoli, T.Z. (2011) An investigation into the culturing of lactate re-utilising CHO cells. Doctoral thesis, UCL (University College London). |
| Papantoniou, I and Hoare, M and Veraitch, FS (2011) The release of single cells from embryoid bodies in a capillary flow device. CHEM ENG SCI , 66 (4) 570 - 581. 10.1016/j.ces.2010.10.026. |
| Parker, BM and Taylor, IN and Woodley, JM and Ward, JM and Dalby, PA (2011) Directed evolution of a thermostable L-aminoacylase biocatalyst. J BIOTECHNOL , 155 (4) 396 - 405. 10.1016/j.jbiotec.2011.07.029. |
| Perez-Pardo, MA and Ali, S and Balasundaram, B and Mannall, GJ and Baganz, F and Bracewell, DG (2011) Assessment of the Manufacturability of Escherichia coli High Cell Density Fermentations. BIOTECHNOL PROGR , 27 (5) 1488 - 1496. 10.1002/btpr.644. |
| Perkins, SJ and Nan, RD and Li, KY and Khan, S and Abe, Y (2011) Analytical ultracentrifugation combined with X-ray and neutron scattering: Experiment and modelling. METHODS , 54 (1) 181 - 199. 10.1016/j.ymeth.2011.01.004. |
| Pesnot, T and Gershater, MC and Ward, JM and Hailes, HC (2011) Phosphate mediated biomimetic synthesis of tetrahydroisoquinoline alkaloids. CHEM COMMUN , 47 (11) 3242 - 3244. 10.1039/c0cc05282e. |
| Polykarpou, E. (2011) Optimisation of chromatography for downstream protein processing. Doctoral thesis, UCL (University College London). | |
| Polykarpou, EM and Dalby, PA and Papageorgiou, LG (2011) Optimal synthesis of chromatographic trains for downstream protein processing. Biotechnol Prog , 27 (6) 1653 - 1660. 10.1002/btpr.670. |
R
| Rayat, A.C.M.E. (2011) Microscale bioprocessing platform for the evaluation of membrane filtration processes for primary recovery. Doctoral thesis, UCL (University College London). | |
| Rios-Solis, L and Halim, M and Cazares, A and Morris, P and Ward, JM and Hailes, HC and Dalby, PA and Baganz, F and Lye, GJ (2011) A toolbox approach for the rapid evaluation of multi-step enzymatic syntheses comprising a 'mix and match' E. coli expression system with microscale experimentation. BIOCATAL BIOTRANSFOR , 29 (5) 192 - 203. 10.3109/10242422.2011.609589. |
S
| Scutcher, M. (2011) Modelling and development of process control for a vascular tissue engineering bioreactor. Doctoral thesis, UCL (University College London). | |
| Shapiro, MS and Haswell, SJ and Lye, GJ and Bracewell, DG (2011) Microfluidic Chromatography for Early Stage Evaluation of Biopharmaceutical Binding and Separation Conditions. SEP SCI TECHNOL , 46 (2) 185 - 194. 10.1080/01496395.2010.511641. |
| Simaria, AS and Gao, Y and Turner, R and Farid, SS (2011) Designing multi-product biopharmaceutical facilities using evolutionary algorithms. In: Pistikopoulos, EN and Georgiadis, MC and Kokossis, AC, (eds.) 21ST EUROPEAN SYMPOSIUM ON COMPUTER AIDED PROCESS ENGINEERING. (pp. 286 - 290). ELSEVIER SCIENCE BV |
| Small, BG and McColl, BW and Allmendinger, R and Pahle, J and López-Castejón, G and Rothwell, NJ and Knowles, J and Mendes, P and Brough, D and Kell, DB (2011) Efficient discovery of anti-inflammatory small-molecule combinations using evolutionary computing. Nat Chem Biol , 7 (12) 902 - 908. 10.1038/nchembio.689. |
| Stonier, A and Pain, D and Westlake, A and Hutchinson, N and Thornhill, NF and Farid, SS (2011) Integration of stochastic simulation with advanced multivariate and visualisation analyses for rapid prediction of facility fit issues in biopharmaceutical processes. In: Pistikopoulos, EN and Georgiadis, MC and Kokossis, AC, (eds.) 21ST EUROPEAN SYMPOSIUM ON COMPUTER AIDED PROCESS ENGINEERING. (pp. 1356 - 1360). ELSEVIER SCIENCE BV |
T
| Tait, A and Hogwood, C and Smales, CM and Bracewell, DG (2011) Host cell protein interactions during the recovery of monoclonal antibodies. In: (Proceedings) BioProcessing, Biologics & Biotherapeutics Congress. |
| Tait, A and Hogwood, C and Ahmad, S and Smales, CM and Bracewell, DG (2011) The interaction of host cell protein dynamics with process variables during the recovery of monoclonal antibodies. In: (Proceedings) Recent Advances in Fermentation Technology (RAFT). |
| Titchener-Hooker, NJ (2011) Exploiting insights to facilitate the integration of upstream and downstream. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. (pp. ? - ?). AMER CHEMICAL SOC |
| Tran, R. (2011) Evaluation of challenges to the ubiquitous nature of chromatography. Doctoral thesis, UCL (University College London). | |
V
| Voulgaris, I and Arnold, SA and Speight, R and Harvey, LM and McNeil, B (2011) Effects of dissolved oxygen availability and culture biomass at induction upon the intracellular expression of monoamine oxidase by recombinant E. coli in fed batch bioprocesses. PROCESS BIOCHEM , 46 (3) 721 - 729. 10.1016/j.procbio.2010.11.019. |
W
| Warburton, PJ and Allan, E and Hunter, S and Ward, J and Booth, V and Wade, WG and Mullany, P (2011) Isolation of bacterial extrachromosomal DNA from human dental plaque associated with periodontal disease, using transposon-aided capture (TRACA). FEMS MICROBIOL ECOL , 78 (2) 349 - 354. 10.1111/j.1574-6941.2011.01166.x. |
Z
| Zhang, J and Hunter, A and Zhou, Y (2011) Systematic Data and Knowledge Utilization to Speed up Bioprocess Design. In: Computer Aided Chemical Engineering. (pp. 1351 - 1355). |