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Number of items: 100.

A

Abdollahpour, H and Appaswamy, G and Kotlarz, D and Diestelhorst, J and Beier, R and Schäffer, AA and Gertz, EM and Schambach, A and Kreipe, HH and Pfeifer, D and Engelhardt, KR and Rezaei, N and Grimbacher, B and Lohrmann, S and Sherkat, R and Klein, C (2012) The phenotype of human STK4 deficiency. Blood , 119 (15) 3450 - 3457. 10.1182/blood-2011-09-378158.

Al-Herz, W and Ragupathy, R and Massaad, MJ and Al-Attiyah, R and Nanda, A and Engelhardt, KR and Grimbacher, B and Notarangelo, L and Chatila, T and Geha, RS (2012) Clinical, immunologic and genetic profiles of DOCK8-deficient patients in Kuwait. Clin Immunol , 143 (3) 266 - 272. 10.1016/j.clim.2012.03.002.

Albert, M and Aydin, S and Su, H and Chatila, T and Alsum, Z and Heinz, V and Al-Herz, W and Keles, S and Picard, C and Gathmann, B and Hoenig, M and Gennery, A and Al-Mousa, H and Geha, RS and Sawalle-Belohradsky, J and Notheis, G and Schwarze, CP and Metin, A and Gaspar, B and Bienemann, K and Schulz, A and Thiel, J and Dueckers, G and Kuijpers, TW and van Montfrans, JM and Ifversen, M and Barlogis, V and Hawwari, A and Holland, SM and Rezaei, N and Al Zahrani, D and Kilic, SS and Genel, F and Kostyuchenko, L and Kainulainen, L and Porras, O and Kumar, A and Ehl, S and Aytekin, C and Gonzalez-Granado, LI and Abbott, J and Kutukculer, N and Marodi, L and Grimbacher, B and Renner, ED and Ochs, H and Belohradsky, BH and Sanal, O and Freeman, AF and Engelhardt, KR and Grp, DS (2012) CLINICAL PRESENTATION AND LONG-TERM OUTCOME OF DOCK8 DEFICIENCY - A SURVEY OF 134 PATIENTS. In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 3 - 3).

Albert, MH and Aydin, S and Alsum, Z and Chatila, T and Su, H and Heinz, V and Al-Herz, W and Keles, S and Picard, C and Kilic, S and Gathmann, B and Hoenig, M and Almousa, H and Sawalle-Belohradsky, J and Gennery, A and Geha, RS and Renner, E and Grimbacher, B and Freeman, AF and Engelhardt, KR (2012) Clinical Presentation, Long-Term Outcome and Therapeutic Management of DOCK8 Deficiency-an International Survey of 125 Patients. In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 359 - 359).

Albert, MH and Aydin, S and Matthes-Martin, S and Hoenig, M and Schulz, A and Picard, C and Barlogis, V and Gennery, A and Ifversen, M and van Montfrans, J and Kuijpers, T and Bredius, R and Dueckers, G and Al-Herz, W and Metin, A and Pai, S and Geha, R and Bittner, TC and Notheis, G and Sawalle-Belohradsky, J and Heinz, V and Gathmann, B and Engelhardt, K and Grimbacher, B and Renner, ED and Chatila, T and Belohradsky, BH and Ochs, HD and Gaspar, B (2012) Management of DOCK8 deficiency by haematopoietic stem cell transplantation. In: BONE MARROW TRANSPLANTATION. (pp. S59 - S60).

Attridge, K and Wang, CJ and Wardzinski, L and Kenefeck, R and Chamberlain, JL and Manzotti, C and Kopf, M and Walker, LS (2012) IL-21 inhibits T cell IL-2 production and impairs Treg homeostasis. Blood , 119 (20) 4656 - 4664. 10.1182/blood-2011-10-388546.

Aydin, S and Freeman, AF and Sanal, O and Al-Mousa, H and Matthes-Martin, S and Cuellar-Rodriguez, J and Hickstein, DD and Tavil, B and Azik, FM and Bittner, TC and Bredius, RG and Ayvaz, D and Kuskonmaz, B and Hoenig, M and Schulz, A and Picard, C and Barlogis, V and Gennery, A and Ifversen, M and van Montfrans, JM and Kuijpers, TW and Dueckers, G and Al-Herz, W and Pai, SY and Geha, RS and Notheis, G and Schwarze, CP and Schuster, F and Gathmann, B and Grimbacher, B and Gaspar, B and Belohradsky, BH and Ochs, H and Renner, E and Chatila, T and Engelhardt, KR and Albert, MH (2012) MANAGEMENT OF DOCK8 DEFICIENCY BY HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT). In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 127 - 128).

B

Bartsch, M and Thiel, J and Cunningham-Rundles, C and Grimbacher, B and Witte, T and Goldacker, S and Venhoff, N and Voll, R and Warnatz, K (2012) IMMUNOSUPPRESSIVE TREATMENT FOR AUTOIMMUNITY, LYMPHOPROLIFERATION AND GRANULOMATOUS COMPLICATIONS IN PATIENTS WITH CVID. In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 157 - 157).

C

Campbell, EC and Antoniou, AN and Powis, SJ (2012) The multi-faceted nature of HLA class I dimer molecules. Immunology , 136 (4) 380 - 384. 10.1111/j.1365-2567.2012.03593.x.

Carpenter, B and Ghorashian, S and Nicholson, E and Griffin, J and Ahmadi, M and Zhang, L and Holler, A and Stauss, H and Morris, E and Chakraverty, R (2012) Targeting therapeutic T cells to tumour niches. In: IMMUNOLOGY. (pp. 53 - 54).

Carpenter, B and Ghorashian, S and Nicholson, E and Griffin, JE and Ahmadi, M and Holler, A and Flutter, B and Edwards, N and Stauss, H and Morris, E and Chakraverty, R (2012) Targeting Therapeutic T Cells to Tumour Niches. In: BLOOD.

Chua, I and Ahmadi, M and Xue, S and Holler, A and Zamoyska, R and Stauss, HJ and Morris, EC (2012) Exploiting CD8 co-receptor to improve the function of genetically modified CD4 T cells for cancer immunotherapy. In: IMMUNOLOGY. (pp. 687 - 687).

Chua, I and Xue, SA and Holler, A and Maniusyte, R and Zamoyska, R and Stauss, HJ and Morris, EC (2012) Exploiting CD8 beta mutations which increase TCR avidity to improve the function of genetically modified T cells for immunotherapy. In: BRITISH JOURNAL OF HAEMATOLOGY. (pp. 87 - 87).

Cunnington, AJ and de Souza, JB and Walther, M and Riley, EM (2012) Malaria impairs resistance to Salmonella through heme- and heme oxygenase-dependent dysfunctional granulocyte mobilization. Nat Med , 18 (1) 120 - 127. 10.1038/nm.2601.

D

Das, A and Ellis, G and Pallant, C and Lopes, AR and Khanna, P and Peppa, D and Chen, A and Blair, P and Dusheiko, G and Gill, U and Kennedy, PT and Brunetto, M and Lampertico, P and Mauri, C and Maini, MK (2012) IL-10-producing regulatory B cells in the pathogenesis of chronic hepatitis B virus infection. J Immunol , 189 (8) 3925 - 3935. 10.4049/jimmunol.1103139.
An open access publication

Depner, M and van de Veerdonk, F and Wanders, J and Stauss, H and Raabe, J and Atkinson, TP and Jr, SHW and Niehues, T and Dueckers, G and Puck, J and Stray-Pedersen, A and Baumann, U and Schmidt, R and Franco, JL and Orrego, J and Ben-Shoshan, M and McCusker, C and Jacob, CMA and Carneiro-Sampaio, M and Devlin, LA and Edgar, JD and Gkrania-Klotsas, E and Kumararatne, D and Doffinger, R and Henderson, P and Russell, RK and Dyrso, T and Seneviratne, SL and Matthijs, G and Abinun, M and Gennery, A and Johnson, M and van der Meer, JWM and Netea, MG and Lilic, D and Grimbacher, B (2012) MUTATION SCREENING IN STAT1, CARD9 AND PKC-DELTA IN PATIENTS WITH CHRONIC MUCOCUTANEOUS CANDIDIASIS. In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 334 - 335).

Depner, M and Wanders, J and Stauss, H and Jansson, A and Dueckers, G and Niehues, T and Baumann, U and Pedersen, AS and Kilic, SS and Atkinson, TP and Puck, JM and Franco, JL and Devlin, L and Jensen, TD and Henderson, P and Matthijs, G and Ben Shoshan, M and McCusker, C and Jacob, CM and Grimbacher, B (2012) Gain-of-function mutations in STAT1: A new molecular cause for patients with chronic mucocutaneous candidiasis. MYCOSES , 55 319 - 319.

Dhanoya, A and Chain, BM and Keshavarz-Moore, E (2012) Role of DNA topology in uptake of polyplex molecules by dendritic cells. Vaccine , 30 (9) 1675 - 1681. 10.1016/j.vaccine.2011.12.102.

E

Engelhardt, K and Gertz, E and Keles, S and Schaeffer, A and Ceja, R and Sassi, A and Graham, L and Massaad, M and Mellouli, F and Benmustapha, I and Khemiri, M and Kilic, S and Etzioni, A and Freeman, A and Thiel, J and Schulze, I and Al-Herz, W and Metin, A and Sanal, O and Yeganeh, M and Niehues, T and Siepermann, K and Weinspach, S and Unal, E and Patiroglu, T and Dasouki, M and Yilmaz, M and Genel, F and Aytekin, C and Kutukculer, N and Somer, A and Kilic, M and Reisli, I and Camcioglu, Y and Gennery, A and Cant, A and Jones, A and Gaspar, H and Pietrogrande, M and Baz, Z and Al-Tamemi, S and Lougaris, V and Lefranc, G and Megarbane, A and Boutros, J and Galal, N and Bejaoui, M and Barbouche, M and Geha, R and Chatila, T and Grimbacher, B (2012) DOCK8 deficiency and diagnostic guidelines for hyper-IgE syndromes. In: ALLERGY. (pp. 163 - 164).

Engelhardt, KR and Gertz, EM and Keles, S and Schaeffer, AA and Ceja, R and Sassi, A and Graham, L and Massaad, MJ and Bejaoui, M and Barbouche, M-R and Geha, RS and Chatila, TA and Grimbacher, B and Phys, 3R (2012) DOCK8 Deficiency and Diagnostic Guidelines for Hyper-IgE Syndromes. In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 361 - 361).

Engelhardt, KR and Gertz, EM and Keles, S and Schaeffer, AA and Ceja, R and Sassi, A and Massaad, MJ and Mellouli, F and Benmustapha, I and Khemiri, M and Kilic, SS and Etzioni, A and Freeman, AF and Thiel, J and Schulze, I and Al-Herz, W and Metin, A and Sanal, O and Yeganeh, M and Niehues, T and Siepermann, K and Unal, E and Patiroglu, T and Dasouki, M and Yilmaz, M and Genel, F and Aytekin, C and Kutukculer, N and Somer, A and Kilic, M and Reisli, I and Camcioglu, Y and Gennery, AR and Cant, AJ and Jones, A and Gaspar, HB and Arkwright, PD and Pietrogrande, MC and Baz, Z and Al-Tamemi, S and Lougaris, V and Lefranc, G and Megarbane, A and Boutros, J and Galal, N and Bejaoui, M and Barbouche, R and Geha, RS and Chatila, TA and Grimbacher, B (2012) DOCK8 DEFICIENCY AND A DIAGNOSTIC SCORE TO DIFFERENTIATE IT FROM OTHER HYPER-IGE SYNDROMES. In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 332 - 333).

Engelhardt, KR and Grimbacher, B (2012) Mendelian traits causing susceptibility to mucocutaneous fungal infections in human subjects. J Allergy Clin Immunol , 129 (2) 294 - 305. 10.1016/j.jaci.2011.12.966.

F

Field, A-C and Stauss, HJ and Morris, EC and Qasim, W (2012) Comparison on lentiviral and Sleeping Beauty transposon-mediated gene expression of T cell receptor genes. In: HUMAN GENE THERAPY. (pp. A10 - A11).

G

Gamez-Diaz, L and Ehl, S and Hauch, H and Koscielniak, E and Feuchtinger, T and Speckmann, C and Wanders, J and Seneviratne, S and Orange, J and Enders, A and Stauss, H and Moustchen, M and Eibel, H and Grimbacher, B (2012) NEW DEFICIENCY CAUSING EARLY-ONSET CVID: HOW TO DIAGNOSE LRBA DEFECTS? In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 77 - 77).

Ghorashian, S and Carpenter, B and Holler, A and Nicholson, E and Ahmadi, M and Zech, M and Bennett, C and Xue, S-A and Morris, E and Stauss, H and Chakraverty, R (2012) CD4 Cells Engineered to Express an MHC Class I Restricted TCR Can Rescue CD8 Cells Tolerized to Tumour-Associated Antigens. In: BLOOD.

Ghorashian, S and Holler, A and Carpenter, B and Ahmadi, M and Nicholson, E and Zech, M and Xue, SA and Bennett, C and Stauss, HJ and Chakraverty, R (2012) CD4 cells expressing an MHC class I restricted TCR can rescue CD8 cells tolerized to tumour-associated antigen. In: IMMUNOLOGY. (pp. 707 - 707).

Ghorashian, S and Holler, A and Flutter, B and Xue, S-A and Fallah-Arani, F and Sivakumaran, J and Bennett, C and Morris, E and Stauss, HJ and Chakraverty, R (2012) CD4 help can overcome tolerance developing in adoptively-transferred T cells transduced with a self-specific TCR. In: HUMAN GENE THERAPY. (pp. A6 - A6).

Giles, J and Shaw, J and Piper, C and Wong-Baeza, I and McHugh, K and Ridley, A and Li, D and Lenart, I and Antoniou, AN and DiGleria, K and Kuroki, K and Maenaka, K and Bowness, P and Kollnberger, S (2012) HLA-B27 homodimers and free H chains are stronger ligands for leukocyte Ig-like receptor B2 than classical HLA class I. J Immunol , 188 (12) 6184 - 6193. 10.4049/jimmunol.1102711.

Glocker, E and Grimbacher, B (2012) Inflammatory bowel disease: is it a primary immunodeficiency? Cell Mol Life Sci , 69 (1) 41 - 48. 10.1007/s00018-011-0837-9.

Guiliano, DB and Fussell, H and Lenart, I and Tsao, E and Nesbeth, D and Fletcher, A and Campbell, EC and Cameron, A and Kellam, P and Hebert, DN and Gould, K and Powis, SJ and Antoniou, AN (2012) HLA-B27 DIMERS ARE TARGETED FOR DEGRADATION BY AN ENDOPLASMIC RETICULUM STRESS INDUCED DEGRADATION PATHWAY - A POTENTIAL NOVEL THERAPEUTIC TARGET? CLINICAL AND EXPERIMENTAL RHEUMATOLOGY , 30 (4) 603 - 603.

Guiliano, DB and Lenart, I and Evans, R and Iwawaki, T and Acord, J and Noursadeghi, M and Nesbeth, D and Campbell, EC and Gould, K and Powis, SJ and Antoniou, AN (2012) HLA-B27 MISFOLDING AND CELLULAR STRESS INFLUENCE THE LIFECYCLE OF INFECTING SALMONELLA? A POTENTIAL MECHANISM FOR SALMONELLA SURVIVAL IN REACTIVE ARTHRITIS PATIENTS? CLINICAL AND EXPERIMENTAL RHEUMATOLOGY , 30 (4) 637 - 637.

H

Hafalla, JC and Claser, C and Couper, KN and Grau, GE and Renia, L and de Souza, JB and Riley, EM (2012) The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology. PLoS Pathog , 8 (2) e1002504 - ?. 10.1371/journal.ppat.1002504.

Havenith, SH and Yong, SL and Henson, SM and Piet, B and Idu, MM and Koch, SD and Jonkers, RE and Kragten, NA and Akbar, AN and van Lier, RA and ten Berge, IJ (2012) Analysis of stem-cell-like properties of human CD161++IL-18Rα+ memory CD8+ T cells. Int Immunol , 24 (10) 625 - 636. 10.1093/intimm/dxs069.

Heaps, AG and Selwood, C and Moody, M and Mari, A and Palazzo, P and Sassi, A and Sawalle-Belohradsky, J and Belohradsky, B and Wollenberg, A and Schimke, L and Renner, E and Woellner, C and Grimbacher, B and El-Shanawany, T and Jolles, S and Williams, P (2012) ANALYSIS OF THE SERUM IGE REPERTOIRE IN HYPER IGE SYNDROME (HIES) PATIENTS USING AN IMMUNO SOLID-PHASE ALLERGEN CHIP (ISAC). In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 31 - 32).

Henson, SM and Macaulay, R and Franzese, O and Akbar, AN (2012) Reversal of functional defects in highly differentiated young and old CD8 T cells by PDL blockade. Immunology , 135 (4) 355 - 363. 10.1111/j.1365-2567.2011.03550.x.

Henson, SM and Riddell, NE and Akbar, AN (2012) Properties of end-stage human T cells defined by CD45RA re-expression. Curr Opin Immunol , 24 (4) 476 - 481. 10.1016/j.coi.2012.04.001.

Hernandez-Trujillo, HS and Chapel, H and Lo Re, V and Notarangelo, LD and Gathmann, B and Grimbacher, B and Boyle, JM and Hernandez-Trujillo, VP and Scalchunes, C and Boyle, ML and Orange, JS (2012) Comparison of American and European practices in the management of patients with primary immunodeficiencies. Clin Exp Immunol , 169 (1) 57 - 69. 10.1111/j.1365-2249.2012.04588.x.

High, KP and Akbar, AN and Nikolich-Zugich, J (2012) Translational research in immune senescence: assessing the relevance of current models. Semin Immunol , 24 (5) 373 - 382. 10.1016/j.smim.2012.04.007.

Hughes, R and Towers, G and Noursadeghi, M (2012) Innate immune interferon responses to human immunodeficiency virus-1 infection. Rev Med Virol , 22 (4) 257 - 266. 10.1002/rmv.1708.

J

Jeffery, LE and Wood, AM and Qureshi, OS and Hou, TZ and Gardner, D and Briggs, Z and Kaur, S and Raza, K and Sansom, DM (2012) Availability of 25-hydroxyvitamin D(3) to APCs controls the balance between regulatory and inflammatory T cell responses. J Immunol , 189 (11) 5155 - 5164. 10.4049/jimmunol.1200786.

K

Kanhere, A and Hertweck, A and Bhatia, U and Gökmen, MR and Perucha, E and Jackson, I and Lord, GM and Jenner, RG (2012) T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements. Nat Commun , 3 1268 - ?. 10.1038/ncomms2260.

Kanhere, A and Jenner, RG (2012) Noncoding RNA localisation mechanisms in chromatin regulation. Silence , 3 (1) 2 - ?. 10.1186/1758-907X-3-2.
An open access publication

Kotlarz, D and Beier, R and Murugan, D and Diestelhorst, J and Jensen, O and Boztug, K and Pfeifer, D and Kreipe, H and Pfister, ED and Baumann, U and Puchalka, J and Bohne, J and Egritas, O and Dalgic, B and Kolho, KL and Sauerbrey, A and Buderus, S and Güngör, T and Enninger, A and Koda, YK and Guariso, G and Weiss, B and Corbacioglu, S and Socha, P and Uslu, N and Metin, A and Wahbeh, GT and Husain, K and Ramadan, D and Al-Herz, W and Grimbacher, B and Sauer, M and Sykora, KW and Koletzko, S and Klein, C (2012) Loss of interleukin-10 signaling and infantile inflammatory bowel disease: implications for diagnosis and therapy. Gastroenterology , 143 (2) 347 - 355. 10.1053/j.gastro.2012.04.045.

Kracker, S and Cuenin, C and Schwartzentruber, J and Robyr, D and Forveille, M and Majewski, J and Grimbacher, B and Kutukuler, N and Herceg, Z and Antonorakis, S and Cavazzana-Calvo, M and Jabado, N and Fischer, A and Durandy, A (2012) A ROLE FOR INO80, A CORE PROTEIN OF A CHROMATIN REMODELING COMPLEX, IN CLASS SWITCH RECOMBINATION. In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 382 - 382).

Kreuzaler, M and Rauch, M and Salzer, U and Birmelin, J and Rizzi, M and Grimbacher, B and Plebani, A and Lougaris, V and Quinti, I and Thon, V and Litzman, J and Schlesier, M and Warnatz, K and Thiel, J and Rolink, AG and Eibel, H (2012) Soluble BAFF levels inversely correlate with peripheral B cell numbers and the expression of BAFF receptors. J Immunol , 188 (1) 497 - 503. 10.4049/jimmunol.1102321.

L

Lachmann, R and Bajwa, M and Vita, S and Smith, H and Cheek, E and Akbar, A and Kern, F (2012) Polyfunctional T cells accumulate in large human cytomegalovirus-specific T cell responses. J Virol , 86 (2) 1001 - 1009. 10.1128/JVI.00873-11.

Lanternier, F and Pathan, S and Vincent, Q and Liu, L and Cypowij, S and Prando, C and Migaud, M and Taibi, L and Ammar-Khodja, A and Stambouli, OB and Guellil, B and Jacobs, F and Goffard, J-C and Shepers, K and del Marmol, V and Bachelez, H and Michel, L and Lefranc, G and Fraitag, S and Bougnoux, M-E and Boudia, M and Lortholary, O and Abel, L and Casanova, J-L and Picard, C and Grimbacher, B and Puel, A (2012) HUMAN INVASIVE DERMATOPHYTIC DISEASE IS CAUSED BY INBORN ERRORS OF CARD9. In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 94 - 94).

Lenart, I and Guiliano, DB and Burn, G and Campbell, EC and Morley, KD and Fussell, H and Powis, SJ and Antoniou, AN (2012) The MHC Class I heavy chain structurally conserved cysteines 101 and 164 participate in HLA-B27 dimer formation. Antioxid Redox Signal , 16 (1) 33 - 43. 10.1089/ars.2010.3693.

Liu, M and Miao, T and Zhu, H and Symonds, AL and Li, L and Schurich, A and Maini, MK and Zhang, J and Kennedy, PT and Li, S and Wang, P (2012) IL-2-engineered nano-APC effectively activates viral antigen-mediated T cell responses from chronic hepatitis B virus-infected patients. J Immunol , 188 (3) 1534 - 1543. 10.4049/jimmunol.1102709.

Loosemore, M and Walsh, SB and Morris, E and Stewart, G and Porter, JB and Montgomery, H (2012) Sudden exertional death in sickle cell trait. Br J Sports Med , 46 (5) 312 - 314. 10.1136/bjsports-2011-090521.

Lopez-Herrera, G and Tampella, G and Baronio, M and Vitali, M and Lougaris, V and Plebani, A and Pan-Hammarstroem, Q and Hammarstroem, L and Du, L and Hultenby, K and Trujillo-Vargas, CM and Phadwal, K and Simon, AK and Moutschen, M and Etzioni, A and Srugo, AMI and Melamed, D and Liu, C and Philippet, P and Dideberg, V and Aghamohammadi, A and Rezai, N and Enright, V and Stauss, H and Herholz, P and Salzer, U and Eibel, H and Pfeifer, D and Velkeen, H and Gertz, EM and Schaeffer, AA and Grimbacher, B (2012) Mutations in LRBA are Associated with a Syndrome of Immune Deficiency and Autoimmunity. In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 363 - 364).

Lopez-Herrera, G and Tampella, G and Pan-Hammarström, Q and Herholz, P and Trujillo-Vargas, CM and Phadwal, K and Simon, AK and Moutschen, M and Etzioni, A and Mory, A and Srugo, I and Melamed, D and Hultenby, K and Liu, C and Baronio, M and Vitali, M and Philippet, P and Dideberg, V and Aghamohammadi, A and Rezaei, N and Enright, V and Du, L and Salzer, U and Eibel, H and Pfeifer, D and Veelken, H and Stauss, H and Lougaris, V and Plebani, A and Gertz, EM and Schäffer, AA and Hammarström, L and Grimbacher, B (2012) Deleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity. Am J Hum Genet , 90 (6) 986 - 1001. 10.1016/j.ajhg.2012.04.015.
An open access publication

Lopez-Herrera, G and Tampella, G and Pan-Hammarstrom, Q and Herholz, P and Trujillo-Vargas, CM and Phadwal, K and Simon, AK and Moutschen, M and Etzioni, A and Mory, A and Srugo, I and Melamed, D and Hultenby, K and Liu, C and Baronio, M and Vitali, M and Philippet, P and Dideberg, V and Aghamohammadi, A and Rezai, N and Enright, V and Du, L and Salzer, U and Eibel, H and Pfeifer, D and Veelken, H and Stauss, H and Lougaris, V and Plebani, A and Gertz, EM and Schaeffer, AA and Hammarstrom, L and Grimbacher, B (2012) DELETERIOUS LRBA MUTATIONS IN A NOVEL SYNDROME OF IMMUNE DEFICIENCY AND AUTOIMMUNITY. In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 251 - 251).

M

Maini, MK and Schurich, A (2012) Platelets harness the immune response to drive liver cancer. Proc Natl Acad Sci U S A , 109 (32) 12840 - 12841. 10.1073/pnas.1210296109.
An open access publication

Matjeka, T and Summerfield, V and Noursadeghi, M and Chain, BM (2012) Chemical toxicity to keratinocytes triggers dendritic cell activation via an IL-1α path. J Allergy Clin Immunol , 129 (1) 247-50.e1-3 - ?. 10.1016/j.jaci.2011.08.018.

McClellan, MJ and Khasnis, S and Wood, CD and Palermo, RD and Schlick, SN and Kanhere, AS and Jenner, RG and West, MJ (2012) Downregulation of integrin receptor-signaling genes by Epstein-Barr virus EBNA 3C via promoter-proximal and -distal binding elements. J Virol , 86 (9) 5165 - 5178. 10.1128/JVI.07161-11.

McCoy, LEF and Forsman-Quigley, A and Strokappe, NM and Bulmer-Thomas, B and Seaman, MS, and Mortier, D and Rutten, L and Chander, N and Edwards, CJ and Ketteler, R and Davis, D and Verrips, CT and Weiss, RA (2012) Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization. Journal of Experimental Medicine

Metzger, M-L and Mueller, I and Melkaoui, K and Litzman, J and Warnatz, K and Guzman, D and Grimbacher, B and Salzer, U (2012) LOW FICOLIN-2 LEVELS IN CVID PATIENTS WITH BRONCHIECTASIS. In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 87 - 87).

Mohamedbhai, SG and Edwards, N and Morris, EC and Mackinnon, S and Thomson, KJ and Peggs, KS (2012) Predominant or complete recipient T-cell chimerism following alemtuzumab-based allogeneic transplantation is reversed by donor lymphocytes and not associated with graft failure. Br J Haematol , 156 (4) 516 - 522. 10.1111/j.1365-2141.2011.08944.x.

N

Nebbia, G and Peppa, D and Maini, MK (2012) Hepatitis B infection: current concepts and future challenges. QJM , 105 (2) 109 - 113. 10.1093/qjmed/hcr270.

Nebbia, G and Peppa, D and Schurich, A and Khanna, P and Singh, HD and Cheng, Y and Rosenberg, W and Dusheiko, G and Gilson, R and ChinAleong, J and Kennedy, P and Maini, MK (2012) Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection. PLOS One , 7 (10) , Article e47648. 10.1371/journal.pone.0047648.
An open access publication. A version is also available from UCL Discovery.
 file

Nicholson, E and Ahmadi, M and Thomas, S and Holler, A and Carpenter, B and Xue, SA and Stauss, H and Morris, E (2012) Enhancing the efficacy of T cell receptor (TCR) gene therapy by co-transfer of TCR and additional CD3 molecules into CD4+T cells. In: BRITISH JOURNAL OF HAEMATOLOGY. (pp. 87 - 87).

Nicholson, E and Ghorashian, S and Stauss, H (2012) Improving TCR Gene Therapy for Treatment of Haematological Malignancies. Adv Hematol , 2012 404081 - ?. 10.1155/2012/404081.
An open access publication

Nicholson, EK and Ahmadi, M and Holler, A and Pike, R and Carpenter, B and Thomas, S and Ghorashian, S and Xue, S-A and Stauss, H and Morris, E (2012) Enhancing the Efficacy of T Cell Receptor (TCR) Gene Therapy by Co-Transfer of TCR and Additional CD3 Molecules Into CD4+T Cells. In: BLOOD.

Nicholson, EK and Ahmadi, M and Holler, A and Pike, R and Carpenter, B and Thomas, S and Ghorashian, S and Xue, S-A and Stauss, H and Morris, E (2012) Enhancing the Efficacy of T Cell Receptor (TCR) Gene Therapy by Co-Transfer of TCR and Additional CD3 Molecules Into CD4+T Cells. In: BLOOD.

O

Orange, JS and Belohradsky, BH and Berger, M and Borte, M and Hagan, J and Jolles, S and Wasserman, RL and Baggish, JS and Saunders, R and Grimbacher, B (2012) Evaluation of correlation between dose and clinical outcomes in subcutaneous immunoglobulin replacement therapy. Clin Exp Immunol , 169 (2) 172 - 181. 10.1111/j.1365-2249.2012.04594.x.

P

Palendira, U and Low, C and Bell, AI and Ma, CS and Abbott, RJ and Phan, TG and Riminton, DS and Choo, S and Smart, JM and Lougaris, V and Giliani, S and Buckley, RH and Grimbacher, B and Alvaro, F and Klion, AD and Nichols, KE and Adelstein, S and Rickinson, AB and Tangye, SG (2012) Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus. J Exp Med , 209 (5) 913 - 924. 10.1084/jem.20112391.

Penaranda, C and Kuswanto, W and Hofmann, J and Kenefeck, R and Narendran, P and Walker, LS and Bluestone, JA and Abbas, AK and Dooms, H (2012) IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells. Proc Natl Acad Sci U S A , 109 (31) 12668 - 12673. 10.1073/pnas.1203692109.

Peppa, D and Maini, MK (2012) Pathogenesis of hepatitis B virus infection and potential for new therapies. Br J Hosp Med (Lond) , 73 (10) 581 - 584.

Powell, N and Walker, AW and Stolarczyk, E and Canavan, JB and Gökmen, MR and Marks, E and Jackson, I and Hashim, A and Curtis, MA and Jenner, RG and Howard, JK and Parkhill, J and MacDonald, TT and Lord, GM (2012) The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells. Immunity , 37 (4) 674 - 684. 10.1016/j.immuni.2012.09.008.

Prokopowicz, Z and Marcinkiewicz, J and Katz, DR and Chain, BM (2012) Neutrophil myeloperoxidase: soldier and statesman. Arch Immunol Ther Exp (Warsz) , 60 (1) 43 - 54. 10.1007/s00005-011-0156-8.

Protzer, U and Maini, MK and Knolle, PA (2012) Living in the liver: hepatic infections. Nat Rev Immunol , 12 (3) 201 - 213. 10.1038/nri3169.

Q

Qureshi, OS and Kaur, S and Hou, TZ and Jeffery, LE and Poulter, NS and Briggs, Z and Kenefeck, R and Willox, AK and Royle, SJ and Rappoport, JZ and Sansom, DM (2012) Constitutive clathrin-mediated endocytosis of CTLA-4 persists during T cell activation. J Biol Chem , 287 (12) 9429 - 9440. 10.1074/jbc.M111.304329.

R

Ramasubramanyan, S and Kanhere, A and Osborn, K and Flower, K and Jenner, RG and Sinclair, AJ (2012) Genome-wide analyses of Zta binding to the Epstein-Barr virus genome reveals interactions in both early and late lytic cycles and an epigenetic switch leading to an altered binding profile. J Virol , 86 (23) 12494 - 12502. 10.1128/JVI.01705-12.

Romberg, N and Chamberlain, N and Saadoun, D and Kinnunen, T and Ng, YS and Martinez-Gallo, M and Matamoros, N and Rachid, R and Geha, RS and Grimbacher, B and Cunningham-Rundles, C and Meffre, E (2012) The Impact of TACI Mutations on Health and CVID. In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 368 - 368).

S

Sandhu, D and Vukmanovic-Stejic, M and Agius, E and Rustin, M and Akbar, A (2012) Early events in the recall response to varicella-zoster virus skin antigen in ageing. In: BRITISH JOURNAL OF DERMATOLOGY. (pp. e36 - e36).

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An open access publication

Speckmann, C and Bondzio, I and Lehmberg, K and Rensing-Ehl, A and Vraetz, T and Grimbacher, B and Albert, M and Belohradsky, BH and Hassan, A and Strahm, B and Schibli, S and Lauten, M and Meerpohl, J and Rodeck, B and Cale, C and Elawad, M and Lorenz, M and zur Stadt, U and Schwarz, K and Ehl, S (2012) XIAP DEFICIENCY: PHENOTYPIC DIVERSITY BEYOND HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS. In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 47 - 47).

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Spielberger, BD and Woellner, C and Dueckers, G and Sawalle-Belohradsky, J and Hagl, B and Anslinger, K and Bayer, B and Siepermann, K and Niehues, T and Grimbacher, B and Belohradsky, BH and Renner, ED (2012) Challenges of genetic counseling in patients with autosomal dominant diseases, such as the hyper-IgE syndrome (STAT3-HIES). J Allergy Clin Immunol , 130 (6) 1426 - 1428. 10.1016/j.jaci.2012.07.030.

T

Thaventhiran, JE and McGovern, N and Dickinson, R and Bigley, V and Doffinger, R and Kumararatne, D and Chee, R and Seneviratne, S and Grimbacher, B and Collin, M and Morris, E (2012) IDENTIFICATION OF GATA-2 MUTATIONS USING A SIMPLE SCREENING PROCEDURE IN PATIENTS WITH PAPILLOMA VIRUS INFECTIONS. In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 83 - 83).

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Thomson, KJ and Kottaridis, P and Cassoni, A and Morris, EC and Khwaja, A and Linch, DC and Chakraverty, R and Peggs, KS and Mackinnon, S (2012) ALLOGENEIC STEM CELL TRANSPLANTATION FOR HIGH-RISK ACUTE MYELOID LEUKEMIA: NO INCREASE IN RELAPSE WITH ALEMTUZUMAB-DEPLETED GRAFTS. In: BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. (pp. S339 - S340).

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An open access publication. A version is also available from UCL Discovery.
 file

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U

Uttenthal, BJ and Carpenter, B and Ghorashian, S and Wright, GP and Flutter, B and Xue, SA and Chakraverty, R and Morris, EC (2012) Adoptive therapy with redirected MHC class I-restricted antigen-specific regulatory T cells is a potential novel cellular therapy for graft-versus-host disease. In: BRITISH JOURNAL OF HAEMATOLOGY. (pp. 8 - 8).

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V

Villegas-Mendez, A and Greig, R and Shaw, TN and de Souza, JB and Gwyer Findlay, E and Stumhofer, JS and Hafalla, JC and Blount, DG and Hunter, CA and Riley, EM and Couper, KN (2012) IFN-γ-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain. J Immunol , 189 (2) 968 - 979. 10.4049/jimmunol.1200688.

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W

Wang, CJ and Kenefeck, R and Wardzinski, L and Attridge, K and Manzotti, C and Schmidt, EM and Qureshi, OS and Sansom, DM and Walker, LS (2012) Cutting edge: cell-extrinsic immune regulation by CTLA-4 expressed on conventional T cells. J Immunol , 189 (3) 1118 - 1122. 10.4049/jimmunol.1200972.

Workman, S and Webster, D and Grimbacher, B and Chee, R and Wanders, J and Symes, A and Neal, M and Sewell, R (2012) COMPARING QOL SCORES FOR PATIENTS WITH IMMUNODEFICIENCIES RECEIVING IV OR SC IMMUNOGLOBULIN THERAPY, AT A SPECIALIST CENTRE OR LOCAL HOSPITAL OR AT HOME. In: JOURNAL OF CLINICAL IMMUNOLOGY. (pp. 350 - 351).

Y

Yong, PF and Freeman, AF and Engelhardt, KR and Holland, S and Puck, JM and Grimbacher, B (2012) An update on the hyper-IgE syndromes. Arthritis Res Ther , 14 (6) 228 - ?. 10.1186/ar4069.

Z

Zech, M and Velica, P and Holler, A and Chakraverty, R and Stauss, H (2012) Manipulating mTOR to enhance T cell mediated tumour immunity in vivo. In: HUMAN GENE THERAPY. (pp. A16 - A16).

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This list was generated on Sat May 25 03:08:58 2013 BST.