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Number of items: 18.
Article
| Belorgey, D and Sharp, LK and Crowther, DC and Onda, M and Johansson, J and Lomas, DA (2004) Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers: implications for the epilepsy seen in the dementia FENIB. Eur J Biochem , 271 (16) 3360 - 3367. 10.1111/j.1432-1033.2004.04270.x. |
| Byrne, E (2004) The physician scientist: an endangered breed? Internal Medicine Journal , 34 (3) 75 - 75. |
| Chow, MK and Lomas, DA and Bottomley, SP (2004) Promiscuous beta-strand interactions and the conformational diseases. Curr Med Chem , 11 (4) 491 - 499. |
| Crowther, DC and Belorgey, D and Miranda, E and Kinghorn, KJ and Sharp, LK and Lomas, DA (2004) Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies. Eur J Hum Genet , 12 (3) 167 - 172. 10.1038/sj.ejhg.5201127. |
| Crowther, DC and Kinghorn, KJ and Page, R and Lomas, DA (2004) Therapeutic targets from a Drosophila model of Alzheimer's disease. Curr Opin Pharmacol , 4 (5) 513 - 516. 10.1016/j.coph.2004.07.001. |
| Janciauskiene, S and Eriksson, S and Callea, F and Mallya, M and Zhou, A and Seyama, K and Hata, S and Lomas, DA (2004) Differential detection of PAS-positive inclusions formed by the Z, Siiyama, and Mmalton variants of alpha1-antitrypsin. Hepatology , 40 (5) 1203 - 1210. 10.1002/hep.20451. |
| Lomas, DA (2004) Lung volume reduction surgery: where are we now? Chron Respir Dis , 1 (1) 2 - 4. |
| Lomas, DA and Belorgey, D and Mallya, M and Onda, M and Kinghorn, KJ and Sharp, LK and Phillips, RL and Page, R and Crowther, DC and Miranda, E (2004) Polymerisation underlies alpha1-antitrypsin deficiency, dementia and other serpinopathies. Front Biosci , 9 2873 - 2891. |
| Lomas, DA and Parfrey, H (2004) Alpha1-antitrypsin deficiency. 4: Molecular pathophysiology. Thorax , 59 (6) 529 - 535. |
| Marotta, R and Chin, J and Quigley, A and Katsabanis, S and Kapsa, R and Byrne, E and Collins, S (2004) Diagnostic screening of mitochondrial DNA mutations in Australian adults 1990-2001. Internal Medicine Journal , 34 (1-2) 10 - 19. |
| Miranda, E and Römisch, K and Lomas, DA (2004) Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulum. J Biol Chem , 279 (27) 28283 - 28291. 10.1074/jbc.M313166200. |
| Parfrey, H and Dafforn, TR and Belorgey, D and Lomas, DA and Mahadeva, R (2004) Inhibiting polymerization - New therapeutic strategies for z alpha(1)-antitrypsin-related emphysema. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY , 31 (2) 133 - 139. 10.1165/rdmb.2003-0276OC. |
| Parfrey, H and Dafforn, TR and Belorgey, D and Lomas, DA and Mahadeva, R (2004) Inhibiting polymerization: new therapeutic strategies for Z alpha1-antitrypsin-related emphysema. Am J Respir Cell Mol Biol , 31 (2) 133 - 139. 10.1165/rcmb.2003-0276OC. |
| Patel, BD and Luben, RN and Welch, AA and Bingham, SA and Khaw, KT and Day, NE and Lomas, DA and Wareham, NJ (2004) Childhood smoking is an independent risk factor for obstructive airways disease in women. Thorax , 59 (8) 682 - 686. 10.1136/thx.2003.010215. |
| Silverman, GA and Lomas, DA (2004) Serpin identification, production, and characterization. Methods , 32 (2) 71 - 72. |
| Zhou, A and Stein, PE and Huntington, JA and Sivasothy, P and Lomas, DA and Carrell, RW (2004) How small peptides block and reverse serpin polymerisation. J Mol Biol , 342 (3) 931 - 941. 10.1016/j.jmb.2004.07.078. |
Proceedings paper
| Carrell, RW and Zhou, AW and Lomas, DA (2004) Neuroserpin provides a structural model for the causation and rational therapy of dementia. In: NEUROBIOLOGY OF AGING. (pp. S47 - S48). |
| Patel, BD and Loo, WJ and Tasker, AD and Screaton, NJ and Burrows, NP and Lomas, DA (2004) Premature facial wrinkling is an external marker of smoking-related chronic obstructive pulmonary disease. In: BRITISH JOURNAL OF DERMATOLOGY. (pp. 9 - 9). |


