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Number of items: 61.

Article

Adib, TR; Henderson, S; Hewitt, D; Bourmpoulia, D; Boshoff, C; Perrett, C; Ledermann, J; (2004) Predicting biomarkers for ovarian cancer using gene-expression microarrays. British Journal of Cancer , 90 (3) 686 - 692. 10.1038/sj.bjc.6601603.

Adib, TR; Henderson, S; Perrett, C; Hewitt, D; Bourmpoulia, D; Ledermann, J; Boshoff, C; (2004) Predicting biomarkers for ovarian cancer using gene-expression microarrays. BRIT J CANCER , 90 (3) 686 - 692. 10.1038/sj.bjc.6601603.

Ahmed, F; Ings, SJ; Pizzey, AR; Blundell, MP; Thrasher, AJ; T Ye, H; ... Yong, KL; + view all (2004) Impaired bone marrow homing of cytokine-activated CD34(+) cells in the NOD/SCID model. BLOOD , 103 (6) 2079 - 2087. 10.1182/blood-2003-06-1770.

Ali, K; Bilancio, A; Pearce, W; Peskett, E; Sawyer, C; Okkenhaug, K; ... Gray, A; + view all (2004) Essential role for the p110δ phosphoinositide 3-kinase in the allergic response. Nature , 431 (7011) 1007 - 1011. 10.1038/nature02991.

Avivi, I; Chakrabarti, S; Milligan, DW; Waldmann, H; Hale, G; Osman, H; ... MacKinnon, S; + view all (2004) Incidence and outcome of Adenovirus disease in transplant recipients after reduced-intensity conditioning with alemtuzumab. BIOL BLOOD MARROW TR , 10 (3) 186 - 194. 10.1016/j.bbmt.2003.11.001.

Baraldi, PG; Beria, I; Cozzi, P; Geroni, C; Espinosa, A; Gallo, MA; ... Romagnoli, R; + view all (2004) Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies. BIOORGAN MED CHEM , 12 (14) 3911 - 3921. 10.1016/j.bmc.2004.04.045.

Belorgey, D; Sharp, LK; Crowther, DC; Onda, M; Johansson, J; Lomas, DA; (2004) Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers: implications for the epilepsy seen in the dementia FENIB. Eur J Biochem , 271 (16) 3360 - 3367. 10.1111/j.1432-1033.2004.04270.x.

Byrne, E; (2004) The physician scientist: an endangered breed? Internal Medicine Journal , 34 (3) 75 - 75.

Calabrese, CR; Almassy, R; Barton, S; Batey, MA; Calvert, AH; Canan-Koch, S; ... Curtin, NJ; + view all (2004) Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361. J NATL CANCER I , 96 (1) 56 - 67. 10.1093/jnci/djh005.

Camilleri, RS; Peebles, D; Portmann, C; Everington, T; Cohen, H; (2004) -455G/A beta-fibrinogen gene polymorphism, factor V Leiden, prothrombin G20210A mutation and MTHFR C677T, and placental vascular complications. BLOOD COAGUL FIBRIN , 15 (2) 139 - 147. 10.1097/01.mbc.0000114378.15192.1a.

Chen, JH; Stoeber, K; Kingsbury, S; Ozanne, SE; Williams, GH; Hales, CN; (2004) Loss of proliferative capacity and induction of senescence in oxidatively stressed human fibroblasts. J BIOL CHEM , 279 (47) 49439 - 49446. 10.1074/jbc.M409153200. Gold open access

Chester, K; Pedley, B; Tolner, B; Violet, J; Mayer, A; Sharma, S; ... Begent, R; + view all (2004) Engineering antibodies for clinical applications in cancer. TUMOR BIOL , 25 (1-2) 91 - 98. 10.1159/000077727.

Chow, MK; Lomas, DA; Bottomley, SP; (2004) Promiscuous beta-strand interactions and the conformational diseases. Curr Med Chem , 11 (4) 491 - 499.

Clark, FJ; Gregg, R; Piper, K; Dunnion, D; Freeman, L; Griffiths, M; ... Chakraverty, R; + view all (2004) Chronic graft-versus-host disease is associated with increased numbers of peripheral blood CD4(+)CD25(high) regulatory T cells. BLOOD , 103 (6) 2410 - 2416. 10.1182/blood-2003-06-2073.

Crowther, DC; Belorgey, D; Miranda, E; Kinghorn, KJ; Sharp, LK; Lomas, DA; (2004) Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies. Eur J Hum Genet , 12 (3) 167 - 172. 10.1038/sj.ejhg.5201127.

Crowther, DC; Kinghorn, KJ; Page, R; Lomas, DA; (2004) Therapeutic targets from a Drosophila model of Alzheimer's disease. Curr Opin Pharmacol , 4 (5) 513 - 516. 10.1016/j.coph.2004.07.001.

Danovi, D; Meulmeester, E; Pasini, D; Migliorini, D; Capra, M; Frenk, R; ... Marine, JC; + view all (2004) Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity. MOL CELL BIOL , 24 (13) 5835 - 5843. 10.1128/MCB.24.13.5835-5843.2004.

Davies, J; Marden, C; Sviland, L; North, J; Lowdell, MW; (2004) Ex-vivo alloreactive T cell depletion with anti-CD69 - Effects on anti-viral immune-reactivity and donor NK cell function. BLOOD CELLS MOLECULES AND DISEASES , 33 (3) 198 - 198.

Davies, JK; Koh, MBC; Lowdell, MW; (2004) Antiviral immunity and T-regulatory cell function are retained after selective alloreactive T-cell depletion in both the HLA-identical and HLA-mismatched settings. BIOL BLOOD MARROW TR , 10 (4) 259 - 268. 10.1016/j.bbmt.2003.12.001.

Davis, BA; O'Sullivan, C; Jarritt, PH; Porter, JB; (2004) Value of sequential monitoring of left ventricular ejection fraction in the management of thalassemia major. BLOOD , 104 (1) 263 - 269. 10.1182/blood-2003-08-2841.

Direkze, NC; Hodivala-Dilke, K; Jeffery, R; Hunt, T; Poulsom, R; Oukrif, D; ... Wright, NA; + view all (2004) Bone marrow contribution to tumor-associated myofibroblasts and fibroblasts. CANCER RES , 64 (23) 8492 - 8495.

Feber, A; Clark, J; Goodwin, G; Dodson, AR; Smith, PH; Fletcher, A; ... Cooper, CS; + view all (2004) Amplification and overexpression of E2F3 in human bladder cancer. ONCOGENE , 23 (8) 1627 - 1630. 10.1038/sj.onc.1207274.

Feingold, EA; Good, PJ; Guyer, MS; Kamholz, S; Liefer, L; Wetterstrand, K; ... ENCODE Project Consortium,; + view all (2004) The ENCODE (ENCyclopedia of DNA elements) Project. SCIENCE , 306 (5296) 636 - 640. 10.1126/science.1105136.

Foster, CS; Falconer, A; Dodson, AR; Norman, AR; Dennis, N; Fletcher, A; ... Cooper, CS; + view all (2004) Transcription factor E2F3 overexpressed in prostate cancer independently predicts clinical outcome. ONCOGENE , 23 (35) 5871 - 5879. 10.1038/sj.onc.1207800.

Freeman, A; Geddes, N; Munson, P; Joseph, J; Ramani, P; Sandison, A; ... Parkinson, MC; + view all (2004) Anaplastic lymphoma kinase (ALK1) staining and molecular analysis in inflammatory myofibroblastic tumours of the bladder: a preliminary clinicopathological study of nine cases and review of the literature. MODERN PATHOL , 17 (7) 765 - 771. 10.1038/modpathol.3800078.

Gissen, P; Johnson, CA; Morgan, NV; Stapelbroek, JM; Forshew, T; Cooper, WN; ... Maher, ER; + view all (2004) Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome. NAT GENET , 36 (4) 400 - 404. 10.1038/ng1325.

Graff, CP; Chester, K; Begent, R; Wittrup, KD; (2004) Directed evolution of an anti-carcinoembryonic antigen scFv with a 4-day monovalent dissociation half-time at 37 degrees C. PROTEIN ENG DES SEL , 17 (4) 293 - 304. 10.1093/protein/gzh038.

Grimwade, D; Enver, T; (2004) Acute promyelocytic leukemia: where does it stem from? LEUKEMIA , 18 (3) 375 - 384. 10.1038/sj.leu.2403234.

Henry, JA; Le, NM; Nguyen, B; Howard, CM; Bailey, SL; Horick, SM; ... Lee, M; + view all (2004) Targeting the inverted CCAAT box 2 in the topoisomerase II alpha promoter by JH-37, an imidazole-pyrrole polyamide hairpin: Design, synthesis, molecular biology, and biophysical studies. BIOCHEMISTRY-US , 43 (38) 12249 - 12257. 10.1021/bi048785z.

Hewison, M; Zehnder, D; Chakraverty, R; Adams, JS; (2004) Vitamin D and barrier function: a novel role for extra-renal 1 alpha-hydroxylase. MOLECULAR AND CELLULAR ENDOCRINOLOGY , 215 (1-2) 31 - 38. 10.1016/j.mce.2003.11.017.

Horton, R; Wilming, L; Rand, V; Lovering, RC; Bruford, EA; Khodiyar, VK; ... Beck, S; + view all (2004) Gene map of the extended human MHC. NAT REV GENET , 5 (12) 889 - 899. 10.1038/nrg1489.

Janciauskiene, S; Eriksson, S; Callea, F; Mallya, M; Zhou, A; Seyama, K; ... Lomas, DA; + view all (2004) Differential detection of PAS-positive inclusions formed by the Z, Siiyama, and Mmalton variants of alpha1-antitrypsin. Hepatology , 40 (5) 1203 - 1210. 10.1002/hep.20451.

Jones, C; Mackay, A; Grigoriadis, A; Cossu, A; Reis-Filho, JS; Fulford, L; ... Lakhani, SR; + view all (2004) Expression profiling of purified normal human luminal and myoepithelial breast cells: Identification of novel prognostic markers for breast cancer. CANCER RES , 64 (9) 3037 - 3045.

Jones, DT; Addison, E; North, JM; Lowdell, MW; Hoffbrand, AV; Mehta, AB; ... Wickremasinghe, RG; + view all (2004) Geldanamycin and herbimycin A induce apoptotic killing of B chronic lymphocytic leukemia cells and augment the cells' sensitivity to cytotoxic drugs. BLOOD , 103 (5) 1855 - 1861. 10.1182/blood-2003-05-1603.

Jones, DT; Addison, E; North, JM; Lowdell, MW; Hoffbrand, AV; Mehta, AB; ... Wickremasinghe, RG; + view all (2004) Geldanamycin and herbimycin A induce apoptotic killing of B chronic lymphocytic leukemia cells and augment the cells' sensitivity to cytotoxic drugs. Blood , 103 (5) 1855 - 1861. 10.1182/blood-2003-05-1603. Green open access
file

Lomas, DA; (2004) Lung volume reduction surgery: where are we now? Chron Respir Dis , 1 (1) 2 - 4.

Lomas, DA; Belorgey, D; Mallya, M; Onda, M; Kinghorn, KJ; Sharp, LK; ... Miranda, E; + view all (2004) Polymerisation underlies alpha1-antitrypsin deficiency, dementia and other serpinopathies. Front Biosci , 9 2873 - 2891.

Lomas, DA; Parfrey, H; (2004) Alpha1-antitrypsin deficiency. 4: Molecular pathophysiology. Thorax , 59 (6) 529 - 535.

Lowe, GDO; Rumley, A; Mackie, IJ; (2004) Plasma fibrinogen. ANN CLIN BIOCHEM , 41 430 - 440.

Marotta, R; Chin, J; Quigley, A; Katsabanis, S; Kapsa, R; Byrne, E; Collins, S; (2004) Diagnostic screening of mitochondrial DNA mutations in Australian adults 1990-2001. Internal Medicine Journal , 34 (1-2) 10 - 19.

Martins, LM; Morrison, A; Klupsch, K; Fedele, V; Moisoi, N; Teismann, P; ... Downward, J; + view all (2004) Neuroprotective role of the reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice. MOL CELL BIOL , 24 (22) 9848 - 9862. 10.1128/MCB.24.22.9848-9862.2004.

McCabe, DJH; Harrison, P; Mackie, IJ; Sidhu, PS; Purdy, G; Lawrie, AS; ... Machin, SJ; + view all (2004) Platelet degranulation and monocyte-platelet complex formation are increased in the acute and convalescent phases after ischaemic stroke or transient ischaemic attack. BRIT J HAEMATOL , 125 (6) 777 - 787. 10.1111/j.1365-2141.2004.04983.x.

McTiernan, A; Whelan, JS; (2004) A Phase II Study of Docetaxel for the Treatment of Recurrent Osteosarcoma. Sarcoma , 8 (2-3) 71 - 76. 10.1080/13577140410001711764. Gold open access

Miranda, E; Römisch, K; Lomas, DA; (2004) Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulum. J Biol Chem , 279 (27) 28283 - 28291. 10.1074/jbc.M313166200. Gold open access

Newsom-Davis, T; Bower, M; Wildfire, A; Thirlwell, C; Nelson, M; Gazzard, B; Stebbing, J; (2004) Resolution of AIDS-related Castleman's disease with anti-CD20 monoclonal antibodies is associated with declining IL-6 and TNF-alpha levels. LEUKEMIA LYMPHOMA , 45 (9) 1939 - 1941. 10.1080/10428190410001693533.

Parfrey, H; Dafforn, TR; Belorgey, D; Lomas, DA; Mahadeva, R; (2004) Inhibiting polymerization - New therapeutic strategies for z alpha(1)-antitrypsin-related emphysema. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY , 31 (2) 133 - 139. 10.1165/rdmb.2003-0276OC.

Parfrey, H; Dafforn, TR; Belorgey, D; Lomas, DA; Mahadeva, R; (2004) Inhibiting polymerization: new therapeutic strategies for Z alpha1-antitrypsin-related emphysema. Am J Respir Cell Mol Biol , 31 (2) 133 - 139. 10.1165/rcmb.2003-0276OC.

Patel, BD; Luben, RN; Welch, AA; Bingham, SA; Khaw, KT; Day, NE; ... Wareham, NJ; + view all (2004) Childhood smoking is an independent risk factor for obstructive airways disease in women. Thorax , 59 (8) 682 - 686. 10.1136/thx.2003.010215.

Ravichandran, D; Kocjan, G; Falzon, M; Ball, RY; Ralphs, DNL; (2004) Imprint cytology of the sentinel lymph node in the assessment of axillary node status in breast carcinoma. EJSO , 30 (3) 238 - 242. 10.1016/j.ejso.2003.11.005.

Rodriguez-Viciana, P; Sabatier, C; McCormick, F; (2004) Signaling specificity by Ras family GTPases is determined by the full spectrum of effectors they regulate. MOL CELL BIOL , 24 (11) 4943 - 4954. 10.1128/MCB.24.11.4943-4954.2004.

Sartor, O; Reid, RH; Hoskin, PJ; Quick, DP; Ell, PJ; Coleman, RE; ... Quadrament 424Sm10-11 Study Grp,; + view all (2004) Samarium-153-lexidronam complex for treatment of painful bone metastases in hormone-refractory prostate cancer. UROLOGY , 63 (5) 940 - 945. 10.1016/j.urology.2004.01.034.

Sharp, TV; Munoz, F; Bourboulia, D; Presneau, N; Darai, E; Wang, HW; ... Boshoff, C; + view all (2004) LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p2l.3, binds pRB and represses E2F-driven transcription. P NATL ACAD SCI USA , 101 (47) 16531 - 16536. 10.1073/pnas.0407123101.

Silverman, GA; Lomas, DA; (2004) Serpin identification, production, and characterization. Methods , 32 (2) 71 - 72.

Stephens, P; Hunter, C; Bignell, G; Edkins, S; Davies, H; Teague, J; ... Canc Genome Project Collaborat Grp,; + view all (2004) Intragenic ERBB2 kinase mutations in tumours. NATURE , 431 (7008) 525 - 526. 10.1038/431525b.

Towatari, M; Ciro, M; Ottolenghi, S; Tsuzuki, S; Enver, T; (2004) Involvement of mitogen-activated protein kinase in the cytokineregulated phosphorylation of transcription factor GATA-1. HEMATOL J , 5 (3) 262 - 272.

Waddington, SN; Nivsarkar, MS; Mistry, AR; Buckley, SMK; Kemball-Cook, G; Mosley, KL; ... Coutelle, C; + view all (2004) Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy. BLOOD , 104 (9) 2714 - 2721. 10.1182/blood-2004-02-0627.

Wang, HW; Trotter, MWB; Lagos, D; Bourboulia, D; Henderson, S; Makinen, T; ... Boshoff, C; + view all (2004) Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma. NAT GENET , 36 (7) 687 - 693. 10.1038/ng1384.

Zhou, A; Stein, PE; Huntington, JA; Sivasothy, P; Lomas, DA; Carrell, RW; (2004) How small peptides block and reverse serpin polymerisation. J Mol Biol , 342 (3) 931 - 941. 10.1016/j.jmb.2004.07.078.

Proceedings paper

Carrell, RW; Zhou, AW; Lomas, DA; (2004) Neuroserpin provides a structural model for the causation and rational therapy of dementia. In: NEUROBIOLOGY OF AGING. (pp. S47 - S48).

Folarin, NI; Baker, RJ; Duke, V; Yogashangary, BC; Vadikolia, C; Wickremasinghe, RG; ... Ganeshaguru, K; + view all (2004) Zap-70 and 19V(H) mutation status in combination with p53 functional analysis identifies the response of poor prognosis B-CLL patients to conventional cytotoxic agents. In: BLOOD. (pp. 527A - 528A). AMER SOC HEMATOLOGY

Patel, BD; Loo, WJ; Tasker, AD; Screaton, NJ; Burrows, NP; Lomas, DA; (2004) Premature facial wrinkling is an external marker of smoking-related chronic obstructive pulmonary disease. In: BRITISH JOURNAL OF DERMATOLOGY. (pp. 9 - 9).

This list was generated on Sun Nov 23 03:29:45 2014 GMT.