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Number of items: 64.


Ahlskog, JKJ; Schliemann, C; Marlind, J; Qureshi, U; Ammar, A; Pedley, RB; Neri, D; (2009) Human monoclonal antibodies targeting carbonic anhydrase IX for the molecular imaging of hypoxic regions in solid tumours. BRIT J CANCER , 101 (4) 645 - 657. 10.1038/sj.bjc.6605200.

Arkenau, HT; Barriuso, J; Olmos, D; Ang, JE; de Bono, J; Judson, I; Kaye, S; (2009) Prospective validation of a prognostic score to improve patient selection for oncology phase I trials. J Clin Oncol , 27 (16) 2692 - 2696. 10.1200/JCO.2008.19.5081.


Bellodi, C; Lidonnici, MR; Hamilton, A; Helgason, GV; Soliera, AR; Ronchetti, M; ... Calabretta, B; + view all (2009) Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells. J CLIN INVEST , 119 (5) 1109 - 1123. 10.1172/JCI35660.

Brunelli, M; Manfrin, E; Martignoni, G; Miller, K; Remo, A; Reghellin, D; ... Bonetti, F; + view all (2009) Genotypic Intratumoral Heterogeneity in Breast Carcinoma With HER2/neu Amplification. AM J CLIN PATHOL , 131 (5) 678 - 682. 10.1309/AJCP09VUTZWZXBMJ.


Camp, PG; Coxson, HO; Levy, RD; Pillai, SG; Anderson, W; Vestbo, J; ... Paré, PD; + view all (2009) Sex differences in emphysema and airway disease in smokers. Chest , 136 (6) 1480 - 1488. 10.1378/chest.09-0676.

Chiou, A; Hägglöf, P; Orte, A; Chen, AY; Dunne, PD; Belorgey, D; ... Klenerman, D; + view all (2009) Probing neuroserpin polymerization and interaction with amyloid-beta peptides using single molecule fluorescence. Biophys J , 97 (8) 2306 - 2315. 10.1016/j.bpj.2009.07.057.


Davies, MJ; Miranda, E; Roussel, BD; Kaufman, RJ; Marciniak, SJ; Lomas, DA; (2009) Neuroserpin polymers activate NF-kappaB by a calcium signaling pathway that is independent of the unfolded protein response. J Biol Chem , 284 (27) 18202 - 18209. 10.1074/jbc.M109.010744.

DeMeo, DL; Mariani, T; Bhattacharya, S; Srisuma, S; Lange, C; Litonjua, A; ... Silverman, EK; + view all (2009) Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. Am J Hum Genet , 85 (4) 493 - 502. 10.1016/j.ajhg.2009.09.004.


Ekeowa, UI; Gooptu, B; Belorgey, D; Hägglöf, P; Karlsson-Li, S; Miranda, E; ... Lomas, DA; + view all (2009) alpha1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies. Clin Sci (Lond) , 116 (12) 837 - 850. 10.1042/CS20080484.

Emuss, V; Lagos, D; Pizzey, A; Gratrix, F; Henderson, SR; Boshoff, C; (2009) KSHV Manipulates Notch Signaling by DLL4 and JAG1 to Alter Cell Cycle Genes in Lymphatic Endothelia. PLoS Pathogens , 5 (10) , Article e1000616. 10.1371/journal.ppat.1000616. Green and gold open access


Fielding, AK; Rowe, JM; Richards, SM; Buck, G; Moorman, AV; Durrant, IJ; ... Goldstone, AH; + view all (2009) Prospective outcome data on 267 unselected adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia confirms superiority of allogeneic transplantation over chemotherapy in the pre-imatinib era: results from the International ALL Trial MRC UKALLXII/ECOG2993. BLOOD , 113 (19) 4489 - 4496. 10.1182/blood-2009-01-199380.


Gandhi, S; Wood-Kaczmar, A; Yao, Z; Plun-Favreau, H; Deas, E; Klupsch, K; ... Abramov, AY; + view all (2009) PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-induced Cell Death. MOL CELL , 33 (5) 627 - 638. 10.1016/j.molcel.2009.02.013. Gold open access

Garofalo, M; Di Leva, G; Romano, G; Nuovo, G; Suh, SS; Ngankeu, A; ... Croce, CM; + view all (2009) miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation. CANCER CELL , 16 (6) 498 - 509. 10.1016/j.ccr.2009.10.014.

Gooptu, B; Ekeowa, UI; Lomas, DA; (2009) Mechanisms of emphysema in alpha1-antitrypsin deficiency: molecular and cellular insights. Eur Respir J , 34 (2) 475 - 488. 10.1183/09031936.00096508.

Gooptu, B; Lomas, DA; (2009) Conformational pathology of the serpins: themes, variations, and therapeutic strategies. Annu Rev Biochem , 78 147 - 176. 10.1146/annurev.biochem.78.082107.133320.

Gooptu, B; Miranda, E; Nobeli, I; Mallya, M; Purkiss, A; Brown, SC; ... Barrett, TE; + view all (2009) Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. J Mol Biol , 387 (4) 857 - 868. 10.1016/j.jmb.2009.01.069.

Graf, T; Enver, T; (2009) Forcing cells to change lineages. NATURE , 462 (7273) 587 - 594. 10.1038/nature08533.

Grimwade, D; Jovanovic, JV; Hills, RK; Nugent, EA; Patel, Y; Flora, R; ... Burnett, AK; + view all (2009) Prospective Minimal Residual Disease Monitoring to Predict Relapse of Acute Promyelocytic Leukemia and to Direct Pre-Emptive Arsenic Trioxide Therapy. J CLIN ONCOL , 27 (22) 3650 - 3658. 10.1200/JCO.2008.20.1533.


Hadjur, S; Williams, LM; Ryan, NK; Cobb, BS; Sexton, T; Fraser, P; ... Merkenschlager, M; + view all (2009) Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus. NATURE , 460 (7253) 410 - U130. 10.1038/nature08079.

Hersh, CP; Hansel, NN; Barnes, KC; Lomas, DA; Pillai, SG; Coxson, HO; ... ICGN Investigators,; + view all (2009) Transforming growth factor-beta receptor-3 is associated with pulmonary emphysema. Am J Respir Cell Mol Biol , 41 (3) 324 - 331. 10.1165/rcmb.2008-0427OC.

Howie, AJ; Brewer, DB; (2009) Optical properties of amyloid stained by Congo red: history and mechanisms. Micron , 40 (3) 285 - 301. 10.1016/j.micron.2008.10.002.


Kim, BS; Miyagawa, F; Cho, Y-H; Bennett, CL; Clausen, BE; Katz, SI; (2009) Keratinocytes Function as Accessory Cells for Presentation of Endogenous Antigen Expressed in the Epidermis. JOURNAL OF INVESTIGATIVE DERMATOLOGY , 129 (12) 2805 - 2817. 10.1038/jid.2009.176.

Kirk, P; Roughton, M; Porter, JB; Walker, JM; Tanner, MA; Patel, J; ... Pennell, DJ; + view all (2009) Cardiac T2*Magnetic Resonance for Prediction of Cardiac Complications in Thalassemia Major. CIRCULATION , 120 (20) 1961 - U23. 10.1161/CIRCULATIONAHA.109.874487.

Knight, A; Mackinnon, S; Lowdell, MW; (2009) CMV-Reactive Gamma/Delta T Cells Expanded From CMV Seronegative Normal Healthy Individuals Lyse CMV-Infected Targets - Potential Adoptive Immunotherapy for Recipients of Stem Cell Transplants From CMV Seronegative Donors. In: BLOOD. (pp. 880 - 880). AMER SOC HEMATOLOGY

Kong, X; Coxson, H; Lomas, DA; Silverman, EK; Pillai, SG; Investigators, ECLIPSE; (2009) Genome-Wide Association Study (GWA) of High Resolution CT Defined Emphysema Phenotypes in Two Independent COPD Populations. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE , 179

Kroeger, H; Miranda, E; MacLeod, I; Pérez, J; Crowther, DC; Marciniak, SJ; Lomas, DA; (2009) Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins. J Biol Chem , 284 (34) 22793 - 22802. 10.1074/jbc.M109.027102.

Kummar, S; Doroshow, JH; Tomaszewski, JE; Calvert, AH; Lobbezoo, M; Giaccone, G; Task Force MDICT,; (2009) Phase 0 clinical trials: Recommendations from the task force on methodology for the development of innovative cancer therapies. EUR J CANCER , 45 (5) 741 - 746. 10.1016/j.ejca.2008.10.024.


Lawrie, AS; Albanyan, A; Cardigan, RA; Mackie, IJ; Harrison, P; (2009) Microparticle sizing by dynamic light scattering in fresh-frozen plasma. VOX SANG , 96 (3) 206 - 212. 10.1111/j.1423-0410.2008.01151.x.

Lee, SM; Woll, PJ; Rudd, R; Ferry, D; O'Brien, M; Middleton, G; ... Hackshaw, A; + view all (2009) Anti-angiogenic therapy using thalidomide combined with chemotherapy in small cell lung cancer: a randomized, double-blind, placebo-controlled trial. J Natl Cancer Inst , 101 (15) 1049 - 1057. 10.1093/jnci/djp200. Green open access

Li, W; Ferguson, BJ; Khaled, WT; Tevendale, M; Stingl, J; Poli, V; ... Watson, CJ; + view all (2009) PML depletion disrupts normal mammary gland development and skews the composition of the mammary luminal cell progenitor pool. P NATL ACAD SCI USA , 106 (12) 4725 - 4730. 10.1073/pnas.0807640106.

Lomas, DA; Silverman, EK; Edwards, LD; Locantore, NW; Miller, BE; Horstman, DH; ... Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints study investigators,; + view all (2009) Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD. Eur Respir J , 34 (1) 95 - 102. 10.1183/09031936.00156508.

Lomas, DA; Silverman, EK; Edwards, LD; Miller, BE; Tal-Singer, R; Investigators, ECLIPSE; (2009) Serum Surfactant Protein D Is Associated with Exacerbations of COPD. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE , 179

Lopez, MN; Pereda, C; Segal, G; Munoz, L; Aguilera, R; Gonzalez, FE; ... Salazar-Onfray, F; + view all (2009) Prolonged Survival of Dendritic Cell-Vaccinated Melanoma Patients Correlates With Tumor-Specific Delayed Type IV Hypersensitivity Response and Reduction of Tumor Growth Factor beta-Expressing T Cells. J CLIN ONCOL , 27 (6) 945 - 952. 10.1200/JCO.2008.18.0794.

Lucas, A; Liu, L; Dai, E; Bot, I; Viswanathan, K; Munuswamy-Ramunujam, G; ... McFadden, G; + view all (2009) The serpin saga; development of a new class of virus derived anti-inflammatory protein immunotherapeutics. Adv Exp Med Biol , 666 132 - 156.


Mansour, MR; Sulis, ML; Duke, V; Foroni, L; Jenkinson, S; Koo, K; ... Linch, DC; + view all (2009) Prognostic Implications of NOTCH1 and FBXW7 Mutations in Adults With T-Cell Acute Lymphoblastic Leukemia Treated on the MRC UKALLXII/ECOG E2993 Protocol. J CLIN ONCOL , 27 (26) 4352 - 4356. 10.1200/JCO.2009.22.0996.

Marciniak, SJ; Lomas, DA; (2009) What can naturally occurring mutations tell us about the pathogenesis of COPD? Thorax , 64 (4) 359 - 364. 10.1136/thx.2008.099408.


Nerelius, C; Sandegren, A; Sargsyan, H; Raunak, R; Leijonmarck, H; Chatterjee, U; ... Johansson, J; + view all (2009) Alpha-helix targeting reduces amyloid-beta peptide toxicity. Proc Natl Acad Sci U S A , 106 (23) 9191 - 9196. 10.1073/pnas.0810364106.


Peggs, KS; Quezada, SA; Chambers, CA; Korman, AJ; Allison, JP; (2009) Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies. J EXP MED , 206 (8) 1717 - 1725. 10.1084/jem.20082492.

Peggs, KS; Thomson, K; Samuel, E; Dyer, G; Armoogum, J; Pang, K; ... Lowdell, MW; + view all (2009) Adoptive Transfer of CMV-Specific Donor T Cells Following Allogeneic Transplantation Leads to Rapid and Safe Systemic Reconstitution. In: BLOOD. (pp. 24 - 24). AMER SOC HEMATOLOGY

Peggs, KS; Verfuerth, S; Pizzey, A; Chow, SLC; Thomson, K; Mackinnon, S; (2009) Cytomegalovirus-Specific T Cell Immunotherapy Promotes Restoration of Durable Functional Antiviral Immunity following Allogeneic Stem Cell Transplantation. CLIN INFECT DIS , 49 (12) 1851 - 1860. 10.1086/648422.

Pillai, SG; Ge, D; Zhu, G; Kong, X; Shianna, KV; Need, AC; ... ICGN Investigators,; + view all (2009) A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci. PLoS Genet , 5 (3) e1000421 . 10.1371/journal.pgen.1000421. Green and gold open access

Pillai, SG; Kong, X; Coxson, H; Lomas, DA; Silverman, EK; Investigators, ECLIPSE; (2009) Association Analysis of Two Novel, Replicated COPD Susceptibility Genes in the ECLIPSE Cohort. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE , 179

Pollard, SM; Yoshikawa, K; Clarke, ID; Danovi, D; Stricker, S; Russell, R; ... Dirks, P; + view all (2009) Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens. CELL STEM CELL , 4 (6) 568 - 580. 10.1016/j.stem.2009.03.014.


Regad, T; Bellodi, C; Nicotera, P; Salomoni, P; (2009) The tumor suppressor Pml regulates cell fate in the developing neocortex. NAT NEUROSCI , 12 (2) 132 - 140. 10.1038/nn.2251.

Rival, T; Page, RM; Chandraratna, DS; Sendall, TJ; Ryder, E; Liu, B; ... Lomas, DA; + view all (2009) Fenton chemistry and oxidative stress mediate the toxicity of the beta-amyloid peptide in a Drosophila model of Alzheimer's disease. Eur J Neurosci , 29 (7) 1335 - 1347. 10.1111/j.1460-9568.2009.06701.x.


Seymour, LW; Ferry, DR; Kerr, DJ; Rea, D; Whitlock, M; Poyner, R; ... Cassidy, J; + view all (2009) Phase II studies of polymer-doxorubicin (PK1, FCE28068) in the treatment of breast, lung and colorectal cancer. INT J ONCOL , 34 (6) 1629 - 1636. 10.3892/ijo_00000293.

Shah, SP; Morin, RD; Khattra, J; Prentice, L; Pugh, T; Burleigh, A; ... Aparicio, S; + view all (2009) Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. NATURE , 461 (7265) 809 - U67. 10.1038/nature08489.

Steele, AJ; Prentice, AG; Hoffbrand, AV; Yogashangary, BC; Hart, SM; Lowdell, MW; ... Wickremasinghe, RG; + view all (2009) 2-phenylacetylenesulfonamide (PAS) induces p53-independent apoptotic killing of B-chronic lymphocytic leukemia (CLL) cells. BLOOD , 114 (6) 1217 - 1225. 10.1182/blood-2008-11-190587.

Steele, AJ; Prentice, AG; Hoffbrand, AV; Yogashangary, BC; Hart, SM; Lowdell, MW; ... Wickremasinghe, RG; + view all (2009) 2-Phenylacetylenesulfonamide (PAS) induces p53-independent apoptotic killing of B-chronic lymphocytic leukemia (CLL) cells. Blood , 114 (6) 1217 - 1225. 10.1182/blood-2008-11-190587.

Steele, AJ; Prentice, AG; Hoffbrand, AV; Yogashangary, BC; Hart, SM; Lowdell, MW; ... Wickremasinghe, RG; + view all (2009) 2-Phenylacetylenesulfonamide (PAS) induces p53-independent apoptotic killing of B-chronic lymphocytic leukemia (CLL) cells. Blood , 114 (6) 1217 - 1225. 10.1182/blood-2008-11-190587.


Taher, A; Cappellini, MD; Vichinsky, E; Galanello, R; Piga, A; Lawniczek, T; ... Porter, JB; + view all (2009) Efficacy and safety of deferasirox doses of > 30 mg/kg per d in patients with transfusion-dependent anaemia and iron overload. BRIT J HAEMATOL , 147 (5) 752 - 759. 10.1111/j.1365-2141.2009.07908.x.

Takehara, S; Onda, M; Zhang, J; Nishiyama, M; Yang, X; Mikami, B; Lomas, DA; (2009) The 2.1-A crystal structure of native neuroserpin reveals unique structural elements that contribute to conformational instability. J Mol Biol , 388 (1) 11 - 20. 10.1016/j.jmb.2009.03.007.

Tan, MH; Smith, AJ; Pawlyk, B; Xu, XY; Liu, XQ; Bainbridge, JB; ... Ali, RR; + view all (2009) Gene therapy for retinitis pigmentosa and Leber congenital amaurosis caused by defects in AIPL1: effective rescue of mouse models of partial and complete Aipl1 deficiency using AAV2/2 and AAV2/8 vectors. Human Molecular Genetics , 18 (12) 2099 - 2114. 10.1093/hmg/ddp133. Green and gold open access

Tipping, AJ; Pina, C; Castor, A; Hong, DL; Rodrigues, NP; Lazzari, L; ... Enver, T; + view all (2009) High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle. BLOOD , 113 (12) 2661 - 2672. 10.1182/blood-2008-06-161117.

Tosello, V; Mansour, MR; Barnes, K; Paganin, M; Sulis, ML; Jenkinson, S; ... Ferrando, AA; + view all (2009) WT1 mutations in T-ALL. BLOOD , 114 (5) 1038 - 1045. 10.1182/blood-2008-12-192039.

Tulpule, S; Shaw, BE; Makoni, P; Little, AM; Madrigal, JA; Goldman, JM; (2009) Severe allergic reaction with anaphylaxis to G-CSF (lenograstim) in a healthy donor. BONE MARROW TRANSPL , 44 (2) 129 - 130. 10.1038/bmt.2008.438.


Velica, P; Davies, NJ; Rocha, PP; Schrewe, H; Ride, JP; Bunce, CM; (2009) Lack of functional and expression homology between human and mouse aldo-keto reductase 1C enzymes: implications for modelling human cancers. MOL CANCER , 8 , Article 121. 10.1186/1476-4598-8-121. Gold open access

Vergote, I; Calvert, H; Kania, M; Kaiser, C; Zimmermann, AH; Sehouli, J; (2009) A randomised, double-blind, phase II study of two doses of pemetrexed in the treatment of platinum-resistant, epithelial ovarian or primary peritoneal cancer. EUR J CANCER , 45 (8) 1415 - 1423. 10.1016/j.ejca.2008.12.013.

Vontell, R; McGuinness, L; Goldring, K; David, D; John, S; (2009) Antigen retrieval improves the immunoreactivity of cells and receptor sites of the basal ganglia on rat and human brains. In: MOVEMENT DISORDERS. (pp. S218 - S218). WILEY-LISS


Wiegant, FA; Surinova, S; Ytsma, E; Langelaar-Makkinje, M; Wikman, G; Post, JA; (2009) Plant adaptogens increase lifespan and stress resistance in C. elegans. Biogerontology , 10 (1) 27 - 42. 10.1007/s10522-008-9151-9.

Wu, P; Davies, FE; Boyd, K; Thomas, K; Dines, S; Saso, RM; ... Morgan, GJ; + view all (2009) The impact of extramedullary disease at presentation on the outcome of myeloma. LEUKEMIA LYMPHOMA , 50 (2) 230 - 235. 10.1080/10428190802657751.


Zhang, EZ; Laufer, JG; Pedley, RB; Beard, PC; (2009) In vivo high-resolution 3D photoacoustic imaging of superficial vascular anatomy. PHYS MED BIOL , 54 (4) 1035 - 1046. 10.1088/0031-9155/54/4/014.

Zhu, G; Agusti, A; Gulsvik, A; Bakke, P; Coxson, H; Lomas, DA; ... ICGN investigators,; + view all (2009) CTLA4 gene polymorphisms are associated with chronic bronchitis. Eur Respir J , 34 (3) 598 - 604. 10.1183/09031936.00141808.

Zhu, G; ICGN Investigators,; Gulsvik, A; Bakke, P; Ghatta, S; Anderson, W; ... Pillai, SG; + view all (2009) Association of TRPV4 gene polymorphisms with chronic obstructive pulmonary disease. Hum Mol Genet , 18 (11) 2053 - 2062. 10.1093/hmg/ddp111.

This list was generated on Sun Oct 26 02:33:31 2014 GMT.