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Jump to: C | D | E | G | H | K | L | M | N | P | R | T | V | Z
Number of items: 20.

C

Camp, PG and Coxson, HO and Levy, RD and Pillai, SG and Anderson, W and Vestbo, J and Kennedy, SM and Silverman, EK and Lomas, DA and Paré, PD (2009) Sex differences in emphysema and airway disease in smokers. Chest , 136 (6) 1480 - 1488. 10.1378/chest.09-0676.

Chiou, A and Hägglöf, P and Orte, A and Chen, AY and Dunne, PD and Belorgey, D and Karlsson-Li, S and Lomas, DA and Klenerman, D (2009) Probing neuroserpin polymerization and interaction with amyloid-beta peptides using single molecule fluorescence. Biophys J , 97 (8) 2306 - 2315. 10.1016/j.bpj.2009.07.057.

D

Davies, MJ and Miranda, E and Roussel, BD and Kaufman, RJ and Marciniak, SJ and Lomas, DA (2009) Neuroserpin polymers activate NF-kappaB by a calcium signaling pathway that is independent of the unfolded protein response. J Biol Chem , 284 (27) 18202 - 18209. 10.1074/jbc.M109.010744.

DeMeo, DL and Mariani, T and Bhattacharya, S and Srisuma, S and Lange, C and Litonjua, A and Bueno, R and Pillai, SG and Lomas, DA and Sparrow, D and Shapiro, SD and Criner, GJ and Kim, HP and Chen, Z and Choi, AM and Reilly, J and Silverman, EK (2009) Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. Am J Hum Genet , 85 (4) 493 - 502. 10.1016/j.ajhg.2009.09.004.

E

Ekeowa, UI and Gooptu, B and Belorgey, D and Hägglöf, P and Karlsson-Li, S and Miranda, E and Pérez, J and MacLeod, I and Kroger, H and Marciniak, SJ and Crowther, DC and Lomas, DA (2009) alpha1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies. Clin Sci (Lond) , 116 (12) 837 - 850. 10.1042/CS20080484.

G

Gooptu, B and Ekeowa, UI and Lomas, DA (2009) Mechanisms of emphysema in alpha1-antitrypsin deficiency: molecular and cellular insights. Eur Respir J , 34 (2) 475 - 488. 10.1183/09031936.00096508.

Gooptu, B and Lomas, DA (2009) Conformational pathology of the serpins: themes, variations, and therapeutic strategies. Annu Rev Biochem , 78 147 - 176. 10.1146/annurev.biochem.78.082107.133320.

Gooptu, B and Miranda, E and Nobeli, I and Mallya, M and Purkiss, A and Brown, SC and Summers, C and Phillips, RL and Lomas, DA and Barrett, TE (2009) Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. J Mol Biol , 387 (4) 857 - 868. 10.1016/j.jmb.2009.01.069.

H

Hersh, CP and Hansel, NN and Barnes, KC and Lomas, DA and Pillai, SG and Coxson, HO and Mathias, RA and Rafaels, NM and Wise, RA and Connett, JE and Klanderman, BJ and Jacobson, FL and Gill, R and Litonjua, AA and Sparrow, D and Reilly, JJ and Silverman, EK and ICGN Investigators, (2009) Transforming growth factor-beta receptor-3 is associated with pulmonary emphysema. Am J Respir Cell Mol Biol , 41 (3) 324 - 331. 10.1165/rcmb.2008-0427OC.

K

Kroeger, H and Miranda, E and MacLeod, I and Pérez, J and Crowther, DC and Marciniak, SJ and Lomas, DA (2009) Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins. J Biol Chem , 284 (34) 22793 - 22802. 10.1074/jbc.M109.027102.

L

Lomas, DA and Silverman, EK and Edwards, LD and Locantore, NW and Miller, BE and Horstman, DH and Tal-Singer, R and Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints study investigators, (2009) Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD. Eur Respir J , 34 (1) 95 - 102. 10.1183/09031936.00156508.

Lucas, A and Liu, L and Dai, E and Bot, I and Viswanathan, K and Munuswamy-Ramunujam, G and Davids, JA and Bartee, MY and Richardson, J and Christov, A and Wang, H and Macaulay, C and Poznansky, M and Zhong, R and Miller, L and Biessen, E and Richardson, M and Sullivan, C and Moyer, R and Hatton, M and Lomas, DA and McFadden, G (2009) The serpin saga; development of a new class of virus derived anti-inflammatory protein immunotherapeutics. Adv Exp Med Biol , 666 132 - 156.

M

Marciniak, SJ and Lomas, DA (2009) What can naturally occurring mutations tell us about the pathogenesis of COPD? Thorax , 64 (4) 359 - 364. 10.1136/thx.2008.099408.

N

Nerelius, C and Sandegren, A and Sargsyan, H and Raunak, R and Leijonmarck, H and Chatterjee, U and Fisahn, A and Imarisio, S and Lomas, DA and Crowther, DC and Strömberg, R and Johansson, J (2009) Alpha-helix targeting reduces amyloid-beta peptide toxicity. Proc Natl Acad Sci U S A , 106 (23) 9191 - 9196. 10.1073/pnas.0810364106.

P

Pillai, SG and Ge, D and Zhu, G and Kong, X and Shianna, KV and Need, AC and Feng, S and Hersh, CP and Bakke, P and Gulsvik, A and Ruppert, A and Lødrup Carlsen, KC and Roses, A and Anderson, W and Rennard, SI and Lomas, DA and Silverman, EK and Goldstein, DB and ICGN Investigators, (2009) A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci. PLoS Genet , 5 (3) e1000421 - ?. 10.1371/journal.pgen.1000421.

R

Rival, T and Page, RM and Chandraratna, DS and Sendall, TJ and Ryder, E and Liu, B and Lewis, H and Rosahl, T and Hider, R and Camargo, LM and Shearman, MS and Crowther, DC and Lomas, DA (2009) Fenton chemistry and oxidative stress mediate the toxicity of the beta-amyloid peptide in a Drosophila model of Alzheimer's disease. Eur J Neurosci , 29 (7) 1335 - 1347. 10.1111/j.1460-9568.2009.06701.x.

T

Takehara, S and Onda, M and Zhang, J and Nishiyama, M and Yang, X and Mikami, B and Lomas, DA (2009) The 2.1-A crystal structure of native neuroserpin reveals unique structural elements that contribute to conformational instability. J Mol Biol , 388 (1) 11 - 20. 10.1016/j.jmb.2009.03.007.

V

Vontell, R and McGuinness, L and Goldring, K and David, D and John, S (2009) Antigen retrieval improves the immunoreactivity of cells and receptor sites of the basal ganglia on rat and human brains. In: MOVEMENT DISORDERS. (pp. S218 - S218). WILEY-LISS

Z

Zhu, G and Agusti, A and Gulsvik, A and Bakke, P and Coxson, H and Lomas, DA and Silverman, EK and Pillai, SG and ICGN investigators, (2009) CTLA4 gene polymorphisms are associated with chronic bronchitis. Eur Respir J , 34 (3) 598 - 604. 10.1183/09031936.00141808.

Zhu, G and ICGN Investigators, and Gulsvik, A and Bakke, P and Ghatta, S and Anderson, W and Lomas, DA and Silverman, EK and Pillai, SG (2009) Association of TRPV4 gene polymorphisms with chronic obstructive pulmonary disease. Hum Mol Genet , 18 (11) 2053 - 2062. 10.1093/hmg/ddp111.

This list was generated on Sat May 18 06:56:12 2013 BST.