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Number of items: 23.

Article

Camp, PG; Coxson, HO; Levy, RD; Pillai, SG; Anderson, W; Vestbo, J; ... Paré, PD; + view all (2009) Sex differences in emphysema and airway disease in smokers. Chest , 136 (6) 1480 - 1488. 10.1378/chest.09-0676.

Chiou, A; Hägglöf, P; Orte, A; Chen, AY; Dunne, PD; Belorgey, D; ... Klenerman, D; + view all (2009) Probing neuroserpin polymerization and interaction with amyloid-beta peptides using single molecule fluorescence. Biophys J , 97 (8) 2306 - 2315. 10.1016/j.bpj.2009.07.057.

Davies, MJ; Miranda, E; Roussel, BD; Kaufman, RJ; Marciniak, SJ; Lomas, DA; (2009) Neuroserpin polymers activate NF-kappaB by a calcium signaling pathway that is independent of the unfolded protein response. J Biol Chem , 284 (27) 18202 - 18209. 10.1074/jbc.M109.010744.

DeMeo, DL; Mariani, T; Bhattacharya, S; Srisuma, S; Lange, C; Litonjua, A; ... Silverman, EK; + view all (2009) Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. Am J Hum Genet , 85 (4) 493 - 502. 10.1016/j.ajhg.2009.09.004.

Ekeowa, UI; Gooptu, B; Belorgey, D; Hägglöf, P; Karlsson-Li, S; Miranda, E; ... Lomas, DA; + view all (2009) alpha1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies. Clin Sci (Lond) , 116 (12) 837 - 850. 10.1042/CS20080484.

Gooptu, B; Ekeowa, UI; Lomas, DA; (2009) Mechanisms of emphysema in alpha1-antitrypsin deficiency: molecular and cellular insights. Eur Respir J , 34 (2) 475 - 488. 10.1183/09031936.00096508.

Gooptu, B; Lomas, DA; (2009) Conformational pathology of the serpins: themes, variations, and therapeutic strategies. Annu Rev Biochem , 78 147 - 176. 10.1146/annurev.biochem.78.082107.133320.

Gooptu, B; Miranda, E; Nobeli, I; Mallya, M; Purkiss, A; Brown, SC; ... Barrett, TE; + view all (2009) Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. J Mol Biol , 387 (4) 857 - 868. 10.1016/j.jmb.2009.01.069.

Hersh, CP; Hansel, NN; Barnes, KC; Lomas, DA; Pillai, SG; Coxson, HO; ... ICGN Investigators,; + view all (2009) Transforming growth factor-beta receptor-3 is associated with pulmonary emphysema. Am J Respir Cell Mol Biol , 41 (3) 324 - 331. 10.1165/rcmb.2008-0427OC.

Kong, X; Coxson, H; Lomas, DA; Silverman, EK; Pillai, SG; Investigators, ECLIPSE; (2009) Genome-Wide Association Study (GWA) of High Resolution CT Defined Emphysema Phenotypes in Two Independent COPD Populations. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE , 179

Kroeger, H; Miranda, E; MacLeod, I; Pérez, J; Crowther, DC; Marciniak, SJ; Lomas, DA; (2009) Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins. J Biol Chem , 284 (34) 22793 - 22802. 10.1074/jbc.M109.027102.

Lomas, DA; Silverman, EK; Edwards, LD; Locantore, NW; Miller, BE; Horstman, DH; ... Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints study investigators,; + view all (2009) Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD. Eur Respir J , 34 (1) 95 - 102. 10.1183/09031936.00156508.

Lomas, DA; Silverman, EK; Edwards, LD; Miller, BE; Tal-Singer, R; Investigators, ECLIPSE; (2009) Serum Surfactant Protein D Is Associated with Exacerbations of COPD. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE , 179

Lucas, A; Liu, L; Dai, E; Bot, I; Viswanathan, K; Munuswamy-Ramunujam, G; ... McFadden, G; + view all (2009) The serpin saga; development of a new class of virus derived anti-inflammatory protein immunotherapeutics. Adv Exp Med Biol , 666 132 - 156.

Marciniak, SJ; Lomas, DA; (2009) What can naturally occurring mutations tell us about the pathogenesis of COPD? Thorax , 64 (4) 359 - 364. 10.1136/thx.2008.099408.

Nerelius, C; Sandegren, A; Sargsyan, H; Raunak, R; Leijonmarck, H; Chatterjee, U; ... Johansson, J; + view all (2009) Alpha-helix targeting reduces amyloid-beta peptide toxicity. Proc Natl Acad Sci U S A , 106 (23) 9191 - 9196. 10.1073/pnas.0810364106.

Pillai, SG; Ge, D; Zhu, G; Kong, X; Shianna, KV; Need, AC; ... ICGN Investigators,; + view all (2009) A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci. PLoS Genet , 5 (3) e1000421 . 10.1371/journal.pgen.1000421. Green and gold open access
file

Pillai, SG; Kong, X; Coxson, H; Lomas, DA; Silverman, EK; Investigators, ECLIPSE; (2009) Association Analysis of Two Novel, Replicated COPD Susceptibility Genes in the ECLIPSE Cohort. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE , 179

Rival, T; Page, RM; Chandraratna, DS; Sendall, TJ; Ryder, E; Liu, B; ... Lomas, DA; + view all (2009) Fenton chemistry and oxidative stress mediate the toxicity of the beta-amyloid peptide in a Drosophila model of Alzheimer's disease. Eur J Neurosci , 29 (7) 1335 - 1347. 10.1111/j.1460-9568.2009.06701.x.

Takehara, S; Onda, M; Zhang, J; Nishiyama, M; Yang, X; Mikami, B; Lomas, DA; (2009) The 2.1-A crystal structure of native neuroserpin reveals unique structural elements that contribute to conformational instability. J Mol Biol , 388 (1) 11 - 20. 10.1016/j.jmb.2009.03.007.

Zhu, G; Agusti, A; Gulsvik, A; Bakke, P; Coxson, H; Lomas, DA; ... ICGN investigators,; + view all (2009) CTLA4 gene polymorphisms are associated with chronic bronchitis. Eur Respir J , 34 (3) 598 - 604. 10.1183/09031936.00141808.

Zhu, G; ICGN Investigators,; Gulsvik, A; Bakke, P; Ghatta, S; Anderson, W; ... Pillai, SG; + view all (2009) Association of TRPV4 gene polymorphisms with chronic obstructive pulmonary disease. Hum Mol Genet , 18 (11) 2053 - 2062. 10.1093/hmg/ddp111.

Proceedings paper

Vontell, R; McGuinness, L; Goldring, K; David, D; John, S; (2009) Antigen retrieval improves the immunoreactivity of cells and receptor sites of the basal ganglia on rat and human brains. In: MOVEMENT DISORDERS. (pp. S218 - S218). WILEY-LISS

This list was generated on Sun Sep 14 03:22:20 2014 BST.