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Number of items: 27.

Article

Agusti, A and Calverley, PM and Celli, B and Coxson, HO and Edwards, LD and Lomas, DA and MacNee, W and Miller, BE and Rennard, S and Silverman, EK and Tal-Singer, R and Wouters, E and Yates, JC and Vestbo, J and Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators, (2010) Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res , 11 122 - ?. 10.1186/1465-9921-11-122.

Belorgey, D and Hägglöf, P and Onda, M and Lomas, DA (2010) pH-dependent stability of neuroserpin is mediated by histidines 119 and 138; implications for the control of beta-sheet A and polymerization. Protein Sci , 19 (2) 220 - 228. 10.1002/pro.299.

Brorsson, A-C and Kumita, JR and MacLeod, I and Bolognesi, B and Speretta, E and Luheshi, LM and Knowles, TPJ and Lomas, DA and Dobson, CM and Crowther, DC (2010) Methods and models in neurodegenerative and systemic protein aggregation diseases. FRONTIERS IN BIOSCIENCE-LANDMARK , 15 373 - 396.

Brorsson, AC and Bolognesi, B and Tartaglia, GG and Shammas, SL and Favrin, G and Watson, I and Lomas, DA and Chiti, F and Vendruscolo, M and Dobson, CM and Crowther, DC and Luheshi, LM (2010) Intrinsic determinants of neurotoxic aggregate formation by the amyloid beta peptide. Biophys J , 98 (8) 1677 - 1684. 10.1016/j.bpj.2009.12.4320.

Chilvers, ER and Lomas, DA (2010) Diagnosing COPD in non-smokers: splitting not lumping. Thorax , 65 (6) 465 - 466. 10.1136/thx.2009.128421.

Cho, MH and Boutaoui, N and Klanderman, BJ and Sylvia, JS and Ziniti, JP and Hersh, CP and DeMeo, DL and Hunninghake, GM and Litonjua, AA and Sparrow, D and Lange, C and Won, S and Murphy, JR and Beaty, TH and Regan, EA and Make, BJ and Hokanson, JE and Crapo, JD and Kong, X and Anderson, WH and Tal-Singer, R and Lomas, DA and Bakke, P and Gulsvik, A and Pillai, SG and Silverman, EK (2010) Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat Genet , 42 (3) 200 - 202. 10.1038/ng.535.

Ekeowa, UI and Freeke, J and Miranda, E and Gooptu, B and Bush, MF and Pérez, J and Teckman, J and Robinson, CV and Lomas, DA (2010) Defining the mechanism of polymerization in the serpinopathies. Proc Natl Acad Sci U S A , 107 (40) 17146 - 17151. 10.1073/pnas.1004785107.

Hall, IP and Lomas, DA (2010) The genetics of obstructive lung disease: big is beautiful. Thorax , 65 (9) 760 - 761. 10.1136/thx.2010.147173.

Hersh, CP and Pillai, SG and Zhu, G and Lomas, DA and Bakke, P and Gulsvik, A and DeMeo, DL and Klanderman, BJ and Lazarus, R and Litonjua, AA and Sparrow, D and Reilly, JJ and Agusti, A and Calverley, PM and Donner, CF and Levy, RD and Make, BJ and Paré, PD and Rennard, SI and Vestbo, J and Wouters, EF and Scholand, MB and Coon, H and Hoidal, J and Silverman, EK (2010) Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene. Am J Respir Crit Care Med , 182 (5) 605 - 613. 10.1164/rccm.200910-1586OC.

Lomas, DA (2010) 25th anniversary Transatlantic Airway Conference: Protein misfolding and obstructive lung disease. Proc Am Thorac Soc , 7 (6) 343 - 345. 10.1513/pats.201001-018AW.

Luheshi, LM and Hoyer, W and de Barros, TP and van Dijk Härd, I and Brorsson, AC and Macao, B and Persson, C and Crowther, DC and Lomas, DA and Ståhl, S and Dobson, CM and Härd, T (2010) Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo. PLoS Biol , 8 (3) e1000334 - ?. 10.1371/journal.pbio.1000334.

Malzer, E and Daly, ML and Moloney, A and Sendall, TJ and Thomas, SE and Ryder, E and Ryoo, HD and Crowther, DC and Lomas, DA and Marciniak, SJ (2010) Impaired tissue growth is mediated by checkpoint kinase 1 (CHK1) in the integrated stress response. J Cell Sci , 123 (Pt 17) 2892 - 2900. 10.1242/jcs.070078.

Marciniak, SJ and Lomas, DA (2010) Alpha1-antitrypsin deficiency and autophagy. N Engl J Med , 363 (19) 1863 - 1864. 10.1056/NEJMcibr1008007.

Miranda, E and Pérez, J and Ekeowa, UI and Hadzic, N and Kalsheker, N and Gooptu, B and Portmann, B and Belorgey, D and Hill, M and Chambers, S and Teckman, J and Alexander, GJ and Marciniak, SJ and Lomas, DA (2010) A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with alpha1-antitrypsin deficiency. Hepatology , 52 (3) 1078 - 1088. 10.1002/hep.23760.

Moloney, A and Sattelle, DB and Lomas, DA and Crowther, DC (2010) Alzheimer's disease: insights from Drosophila melanogaster models. Trends Biochem Sci , 35 (4) 228 - 235. 10.1016/j.tibs.2009.11.004.

Munuswamy-Ramanujam, G and Dai, E and Liu, L and Shnabel, M and Sun, YM and Bartee, M and Lomas, DA and Lucas, AR (2010) Neuroserpin, a thrombolytic serine protease inhibitor (serpin), blocks transplant vasculopathy with associated modification of T-helper cell subsets. Thromb Haemost , 103 (3) 545 - 555. 10.1160/TH09-07-0441.

Pillai, SG and Kong, X and Edwards, LD and Cho, MH and Anderson, WH and Coxson, HO and Lomas, DA and Silverman, EK and ECLIPSE and ICGN Investigators, (2010) Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease. Am J Respir Crit Care Med , 182 (12) 1498 - 1505. 10.1164/rccm.201002-0151OC.

Rashid, ST and Corbineau, S and Hannan, N and Marciniak, SJ and Miranda, E and Alexander, G and Huang-Doran, I and Griffin, J and Ahrlund-Richter, L and Skepper, J and Semple, R and Weber, A and Lomas, DA and Vallier, L (2010) Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. J Clin Invest , 120 (9) 3127 - 3136. 10.1172/JCI43122.

Sørheim, IC and Bakke, P and Gulsvik, A and Pillai, SG and Johannessen, A and Gaarder, PI and Campbell, EJ and Agustí, A and Calverley, PM and Donner, CF and Make, BJ and Rennard, SI and Vestbo, J and Wouters, EF and Paré, PD and Levy, RD and Coxson, HO and Lomas, DA and Hersh, CP and Silverman, EK (2010) α₁-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts. Chest , 138 (5) 1125 - 1132. 10.1378/chest.10-0746.

Sørheim, IC and DeMeo, DL and Washko, G and Litonjua, A and Sparrow, D and Bowler, R and Bakke, P and Pillai, SG and Coxson, HO and Lomas, DA and Silverman, EK and Hersh, CP and International COPD Genetics Network Investigators, (2010) Polymorphisms in the superoxide dismutase-3 gene are associated with emphysema in COPD. COPD , 7 (4) 262 - 268. 10.3109/15412555.2010.496821.

Vontell, R and Segovia, KN and Betzl, AJ and Mingote, S and Goldring, K and Cartun, RW and Salamone, JD (2010) Immunocytochemistry Studies of Basal Ganglia Adenosine A(2A) Receptors in Rat and Human Tissue. J HISTOTECHNOL , 33 (1) 41 - 47.

Proceedings paper

Bafadhel, M and McKenna, S and Terry, S and Mistry, V and Reid, C and Haldar, P and McCormick, M and Haldar, K and Kebadze, T and Duvoix, A and Lindbald, K and Rugman, P and Dodson, P and Jenkins, M and Newbold, P and Venge, P and Green, RH and Lomas, DA and Barer, MR and Johnston, SL and Pavord, ID and Brightling, CE (2010) ACUTE EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE: IDENTIFICATION OF PHENOTYPE-SPECIFIC BIOMARKERS AND BIOLOGICAL CLUSTERS. In: THORAX. (pp. A3 - A3).

Nyon, M-P and Levy, G and Kirkpatrick, J and Ekeowa, U and Lomas, DA and Cabrita, LD and Christodoulou, J and Mckay, A and Gooptu, B (2010) USE OF NMR SPECTROSCOPY AND NANOSPRAY MASS SPECTROMETRY TO CHARACTERISE BINDING OF LEAD COMPOUNDS FOR DRUG DESIGN IN alpha 1-ANTITRYPSIN DEFICIENCY. In: THORAX. (pp. A30 - A30).

Nyon, MP and Segu, L and Roussel, B and Kalsheker, N and Lomas, DA and Thalassinos, K and Gooptu, B (2010) CHARACTERISATION OF A NOVEL "PSEUDO-Z" VARIANT OF alpha 1-ANTITRYPSIN. In: THORAX. (pp. A30 - A30). B M J PUBLISHING GROUP

Patel, BD and Coxson, HO and Camp, PG and Pillai, SG and Agusti, AG and Calverley, PM and Donner, CF and Make, BJ and Mueller, NL and Rennard, SI and Vestbo, J and Wouters, EF and Anderson, WH and Pare, PD and Levy, RD and Silverman, EK and Lomas, DA (2010) THE EFFECT OF SMALL AIRWAYS DISEASE AND EMPHYSEMA ON THE ASSOCIATION BETWEEN SMOKING AND LUNG FUNCTION, AND BRONCHODILATOR RESPONSE. In: THORAX. (pp. A52 - A52).

Rashid, ST and Marciniak, SJ and Miranda, E and Alexander, GJ and Lomas, DA and Vallier, L (2010) USE OF HUMAN INDUCED PLURIPOTENT STEM CELLS (HIPSCS) FOR IN VITRO MODELLING OF LIVER DISEASE. In: HEPATOLOGY. (pp. 424A - 425A).

Thesis

Chaudhry, S.I. (2010) Analysis of squamous cell carcinoma invasion identifies a role for TRAF6. Doctoral thesis, UCL (University College London).
An open access version is available from UCL Discovery
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This list was generated on Thu May 23 09:13:42 2013 BST.