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Article

Agusti, A; Calverley, PM; Celli, B; Coxson, HO; Edwards, LD; Lomas, DA; ... Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators,; + view all (2010) Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res , 11 122 - ?. 10.1186/1465-9921-11-122.

Alpendurada, F; Carpenter, JP; Deac, M; Kirk, P; Walker, JM; Porter, JB; ... Pennell, DJ; + view all (2010) Relation of myocardial T2*to right ventricular function in thalassaemia major. EUR HEART J , 31 (13) 1648 - 1654. 10.1093/eurheartj/ehq106.

Altshuler, D; Durbin, RM; Abecasis, GR; Bentley, DR; Chakravarti, A; Clark, AG; ... Consortium, 1GP; + view all (2010) A map of human genome variation from population-scale sequencing. NATURE , 467 (7319) 1061 - 1073. 10.1038/nature09534.

Andre, R; Schure, U; Magnusson, A; Lahiri, N; Smith, D; Lowdell, MW; ... Tabrizi, SJ; + view all (2010) MYELOID CELL FUNCTION IN MOUSE MODELS OF HUNTINGTON'S DISEASE. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , 81 A5 - A6. 10.1136/jnnp.2010.222570.17.

Antonow, D; Kaliszczak, M; Kang, GD; Coffils, M; Tiberghien, AC; Cooper, N; ... Thurston, DE; + view all (2010) Structure-Activity Relationships of Monomeric C2-Aryl Pyrrolo[2,1-c][1,4]benzodiazepine (PBD) Antitumor Agents. J MED CHEM , 53 (7) 2927 - 2941. 10.1021/jm901722v.

Austin, S; Cohen, H; (2010) Antiphospholipid syndrome. Medicine , 38 (2) 101 - 104. 10.1016/j.mpmed.2009.10.012.

Azzato, EM; Lee, AJX; Teschendorff, A; Ponder, BAJ; Pharoah, P; Caldas, C; Maia, AT; (2010) Common germ-line polymorphism of C1QA and breast cancer survival. BRIT J CANCER , 102 (8) 1294 - 1299. 10.1038/sj.bjc.6605625.

Bartesaghi, S; Betts-Henderson, J; Cain, K; Dinsdale, D; Zhou, XS; Karlsson, A; ... Nicotera, P; + view all (2010) Loss of thymidine kinase 2 alters neuronal bioenergetics and leads to neurodegeneration. HUM MOL GENET , 19 (9) 1669 - 1677. 10.1093/hmg/ddq043.

Bartlett, JMS; Campbell, FM; Ibrahim, M; Thomas, J; Wencyk, P; Ellis, I; ... Miller, K; + view all (2010) A UK NEQAS ICC and ISH multicentre study using the Kreatech Poseidon HER2 FISH probe: intersite variation can be rigorously controlled using FISH. HISTOPATHOLOGY , 56 (3) 297 - 304. 10.1111/j.1365-2559.2010.03493.x.

Beck, S; (2010) A-Z of methylome analysis Introduction. METHODS , 52 (3) 201 - 202. 10.1016/j.ymeth.2010.10.003.

Beck, S; (2010) Taking the measure of the methylome. NAT BIOTECHNOL , 28 (10) 1026 - 1028. 10.1038/nbt1010-1026.

Bejugam, M; Gunaratnam, M; Müller, S; Sanders, DA; Sewitz, S; Fletcher, JA; ... Balasubramanian, S; + view all (2010) Correction to Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines. ACS Med Chem Lett , 1 (9) 546 - ?. 10.1021/ml100241w.

Bejugam, M; Gunaratnam, M; Müller, S; Sanders, DA; Sewitz, S; Fletcher, JA; ... Balasubramanian, S; + view all (2010) Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines. ACS Med Chem Lett , 1 (7) 306 - 310. 10.1021/ml100062z.

Bell, CG; Beck, S; (2010) The epigenomic interface between genome and environment in common complex diseases. BRIEF FUNCT GENOMICS , 9 (5-6) 477 - 485. 10.1093/bfgp/elq026.

Bell, CG; Finer, S; Lindgren, CM; Wilson, GA; Rakyan, VK; Teschendorff, AE; ... Int Type 2 Diabet 1q Consortium,; + view all (2010) Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus. PLOS ONE , 5 (11) , Article e14040. 10.1371/journal.pone.0014040. Green and gold open access
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Bell, CG; Teschendorff, AE; Rakyan, VK; Maxwell, AP; Beck, S; Savage, DA; (2010) Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus. BMC Medical Genomics , 3 , Article 33. 10.1186/1755-8794-3-33. Green and gold open access
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Belorgey, D; Hägglöf, P; Onda, M; Lomas, DA; (2010) pH-dependent stability of neuroserpin is mediated by histidines 119 and 138; implications for the control of beta-sheet A and polymerization. Protein Sci , 19 (2) 220 - 228. 10.1002/pro.299.

Benkhelifa-Ziyyat, S; Bucher, S; Zanta-Boussif, MA; Pasquet, J; Danos, O; (2010) Changes in the accessibility of the HIV-1 Integrase C-terminus in the presence of cellular proteins. Retrovirology , 7 27 - ?. 10.1186/1742-4690-7-27.

Berro, M; Mayor, NP; Maldonado-Torres, H; Cooke, L; Kusminsky, G; Marsh, SGE; ... Shaw, BE; + view all (2010) Association of functional polymorphisms of the transforming growth factor B1 gene with survival and graft-versus-host disease after unrelated donor hematopoietic stem cell transplantation. HAEMATOL-HEMATOL J , 95 (2) 276 - 283. 10.3324/haematol.2009.010835. Gold open access

Betts-Henderson, J; Bartesaghi, S; Crosier, M; Lindsay, S; Chen, HL; Salomoni, P; ... Nicotera, P; + view all (2010) The nystagmus-associated FRMD7 gene regulates neuronal outgrowth and development. HUM MOL GENET , 19 (2) 342 - 351. 10.1093/hmg/ddp500.

Bjedov, I; Toivonen, JM; Kerr, F; Slack, C; Jacobson, J; Foley, A; Partridge, L; (2010) Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster. Cell Metabolism , 11 (1) 35 - 46. 10.1016/j.cmet.2009.11.010. Green and gold open access
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Bolli, N; Payne, EM; Grabher, C; Lee, JS; Johnston, AB; Falini, B; ... Look, AT; + view all (2010) Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish. Blood , 115 (16) 3329 - 3340. 10.1182/blood-2009-02-207225.

Bonnet, J; Wang, YH; Spedale, G; Atkinson, RA; Romier, C; Hamiche, A; ... Kieffer, B; + view all (2010) The structural plasticity of SCA7 domains defines their differential nucleosome-binding properties. EMBO Rep , 11 (8) 612 - 618. 10.1038/embor.2010.98.

Boss, DS; Schwartz, GK; Middleton, MR; Amakye, DD; Swaisland, H; Midgley, RS; ... Shapiro, GI; + view all (2010) Safety, tolerability, pharmacokinetics and pharmacodynamics of the oral cyclin-dependent kinase inhibitor AZD5438 when administered at intermittent and continuous dosing schedules in patients with advanced solid tumours. ANN ONCOL , 21 (4) 884 - 894. 10.1093/annonc/mdp377.

Braconi, C; Valeri, N; Gasparini, P; Huang, NY; Taccioli, C; Nuovo, G; ... Patel, T; + view all (2010) Hepatitis C Virus Proteins Modulate MicroRNA Expression and Chemosensitivity in Malignant Hepatocytes. CLIN CANCER RES , 16 (3) 957 - 966. 10.1158/1078-0432.CCR-09-2123.

Brada, M; Stenning, S; Gabe, R; Thompson, LC; Levy, D; Rampling, R; ... Lee, SM; + view all (2010) Temozolomide Versus Procarbazine, Lomustine, and Vincristine in Recurrent High-Grade Glioma. JOURNAL OF CLINICAL ONCOLOGY , 28 (30) 4601 - 4608. 10.1200/JCO.2009.27.1932.

Branchini, BR; Ablamsky, DM; Davis, AL; Southworth, TL; Butler, B; Fan, F; ... Pule, MA; + view all (2010) Red-emitting luciferases for bioluminescence reporter and imaging applications. ANAL BIOCHEM , 396 (2) 290 - 297. 10.1016/j.ab.2009.09.009.

Bridgewater, J; Wasan, H; Valle, J; (2010) Cisplatin plus Gemcitabine for Biliary Tract Cancer REPLY. NEW ENGLAND JOURNAL OF MEDICINE , 363 (2) 192 - 193.

Brooks, SP; Coccia, M; Tang, HR; Kanuga, N; Machesky, LM; Bailly, M; ... Hardcastle, AJ; + view all (2010) The Nance-Horan syndrome protein encodes a functional WAVE homology domain (WHD) and is important for co-ordinating actin remodelling and maintaining cell morphology. HUM MOL GENET , 19 (12) 2421 - 2432. 10.1093/hmg/ddq125.

Brorsson, A-C; Kumita, JR; MacLeod, I; Bolognesi, B; Speretta, E; Luheshi, LM; ... Crowther, DC; + view all (2010) Methods and models in neurodegenerative and systemic protein aggregation diseases. FRONTIERS IN BIOSCIENCE-LANDMARK , 15 373 - 396.

Brorsson, AC; Bolognesi, B; Tartaglia, GG; Shammas, SL; Favrin, G; Watson, I; ... Luheshi, LM; + view all (2010) Intrinsic determinants of neurotoxic aggregate formation by the amyloid beta peptide. Biophys J , 98 (8) 1677 - 1684. 10.1016/j.bpj.2009.12.4320.

Brunetto, AT; Ang, JE; Olmos, D; Tan, D; Barriuso, J; Arkenau, HT; ... Kaye, S; + view all (2010) A study of the pattern of hospital admissions in a specialist Phase I oncology trials unit: unplanned admissions as an early indicator of patient attrition. Eur J Cancer , 46 (15) 2739 - 2745. 10.1016/j.ejca.2010.06.123.

Brunetto, AT; De Bono, JS; Kristeleit, RS; (2010) Early oncology clinical trial design in the era of molecular-targeted agents. Future Oncology , 6 (8) 1339 - 1352. 10.2217/fon.10.92.

Butcher, LM; Beck, S; (2010) AutoMeDIP-seq: A high-throughput, whole genome, DNA methylation assay. METHODS , 52 (3) 223 - 231. 10.1016/j.ymeth.2010.04.003. Gold open access

Cappellini, MD; Porter, J; El-Beshlawy, A; Li, CK; Seymour, JF; Elalfy, M; ... EPIC Study Investigators,; + view all (2010) Tailoring iron chelation by iron intake and serum ferritin: the prospective EPIC study of deferasirox in 1744 patients with transfusion-dependent anemias. HAEMATOL-HEMATOL J , 95 (4) 557 - 566. 10.3324/haematol.2009.014696. Gold open access

Carpenter, JP; Alpendurada, F; Deac, M; Maceira, A; Garbowski, M; Kirk, P; ... Pennell, DJ; + view all (2010) Right ventricular volumes and function in thalassemia major patients in the absence of myocardial iron overload. Journal of Cardiovascular Magnetic Resonance , 12 , Article 24. 10.1186/1532-429X-12-24. Green and gold open access
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Castleton, AZ; Brazma, D; Howard-Reeves, J; Chanalaris, A; Glanville, J; Nizetic, D; ... Nacheva, EP; + view all (2010) Genome gains at chromosome 21q21/22 segment leads to co-amplification of Down Syndrome Critical Regions and known oncogenes in a case of donor cell-derived acute myeloid leukaemia following allogeneic sex mismatched umbilical cord blood transplantation for chronic myeloid leukaemia. BRIT J HAEMATOL , 151 (3) 285 - 288. 10.1111/j.1365-2141.2010.08350.x.

Chan, W-C; Liang, P-H; Shih, Y-P; Yang, U-C; Lin, W-C; Hsu, C-N; (2010) Learning to predict expression efficacy of vectors in recombinant protein production. BMC Bioinformatics , 11 (Suppl 1) S21 - S21. 10.1186/1471-2105-11-S1-S21. Gold open access

Chappert, P; Leboeuf, M; Rameau, P; Lalfer, M; Desbois, S; Liblau, RS; ... Gross, DA; + view all (2010) Antigen-specific Treg impair CD8(+) T-cell priming by blocking early T-cell expansion. Eur J Immunol , 40 (2) 339 - 350. 10.1002/eji.200839107.

Chavda, S; Babu, B; Yanow, SK; Jardim, A; Spithill, TW; Kiakos, K; ... Lee, M; + view all (2010) A novel achiral seco-cyclopropylpyrido[e]indolone (CPyI) analog of CC-1065 and the duocarmycins: Synthesis, DNA interactions, in vivo anticancer and anti-parasitic evaluation. BIOORGAN MED CHEM , 18 (14) 5016 - 5024. 10.1016/j.bmc.2010.05.078.

Chilvers, ER; Lomas, DA; (2010) Diagnosing COPD in non-smokers: splitting not lumping. Thorax , 65 (6) 465 - 466. 10.1136/thx.2009.128421.

Cho, MH; Boutaoui, N; Klanderman, BJ; Sylvia, JS; Ziniti, JP; Hersh, CP; ... Silverman, EK; + view all (2010) Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat Genet , 42 (3) 200 - 202. 10.1038/ng.535.

Ciau-Uitz, A; Pinheiro, P; Gupta, R; Enver, T; Patient, R; (2010) Tel1/ETV6 Specifies Blood Stem Cells through the Agency of VEGF Signaling. DEV CELL , 18 (4) 569 - 578. 10.1016/j.devcel.2010.02.009.

Cohen, H; Machin, SJ; (2010) Antithrombotic treatment failures in antiphospholipid syndrome: the new anticoagulants? LUPUS , 19 (4) 486 - 491. 10.1177/0961203310361355.

Cornils, H; Stegert, MR; Hergovich, A; Hynx, D; Schmitz, D; Dirnhofer, S; Hemmings, BA; (2010) Ablation of the Kinase NDR1 Predisposes Mice to the Development of T Cell Lymphoma. SCI SIGNAL , 3 (126) , Article ra47. 10.1126/scisignal.2000681.

Craddock, C; Nagra, S; Peniket, A; Brookes, C; Buckley, L; Nikolousis, E; ... Russell, N; + view all (2010) Factors predicting long-term survival after T-cell depleted reduced intensity allogeneic stem cell transplantation for acute myeloid leukemia. HAEMATOL-HEMATOL J , 95 (6) 989 - 995. 10.3324/haematol.2009.013920. Gold open access

Cross, TJS; Calvaruso, V; Maimone, S; Carey, I; Chang, TP; Pleguezuelo, M; ... Harrison, PM; + view all (2010) Prospective comparison of Fibroscan, King's score and liver biopsy for the assessment of cirrhosis in chronic hepatitis C infection. J VIRAL HEPATITIS , 17 (8) 546 - 554. 10.1111/j.1365-2893.2009.01210.x.

Danovi, D; Cremona, CA; Machado-da-Silva, G; Basu, S; Noon, LA; Parrinello, S; Lloyd, AC; (2010) A Genetic Screen for Anchorage-Independent Proliferation in Mammalian Cells Identifies a Membrane-Bound Neuregulin. PLOS ONE , 5 (7) , Article e11774. 10.1371/journal.pone.0011774. Green and gold open access
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Danovi, D; Falk, A; Humphreys, P; Vickers, R; Tinsley, J; Smith, AG; Pollard, SM; (2010) Imaging-based chemical screens using normal and glioma-derived neural stem cells. BIOCHEM SOC T , 38 1067 - 1071. 10.1042/BST0381067.

das Neves, RP; Jones, NS; Andreu, L; Gupta, R; Enver, T; Iborra, FJ; (2010) Connecting Variability in Global Transcription Rate to Mitochondrial Variability. PLOS BIOL , 8 (12) , Article e1000560. 10.1371/journal.pbio.1000560. Green and gold open access
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Davis, OSP; Butcher, LM; Docherty, SJ; Meaburn, EL; Curtis, CJC; Simpson, MA; ... Plomin, R; + view all (2010) A Three-Stage Genome-Wide Association Study of General Cognitive Ability: Hunting the Small Effects. BEHAV GENET , 40 (6) 759 - 767. 10.1007/s10519-010-9350-4.

de Pagter, PJ; Virgili, A; Nacheva, E; van Baarle, D; Schuurman, R; Boelens, JJ; (2010) Chromosomally integrated human herpesvirus 6: transmission via cord blood-derived unrelated hematopoietic stem cell transplantation. Biol Blood Marrow Transplant , 16 (1) 130 - 132. 10.1016/j.bbmt.2009.05.009.

Dedes, KJ; Lopez-Garcia, MA; Geyer, FC; Lambros, MB; Savage, K; Vatcheva, R; ... Reis-Filho, JS; + view all (2010) Cortactin gene amplification and expression in breast cancer: a chromogenic in situ hybridisation and immunohistochemical study. Breast Cancer Res Treat , 124 (3) 653 - 666. 10.1007/s10549-010-0816-0.

Dedes, KJ; Wetterskog, D; Mendes-Pereira, AM; Natrajan, R; Lambros, MB; Geyer, FC; ... Reis-Filho, JS; + view all (2010) PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors. Sci Transl Med , 2 (53) 53ra75 - ?. 10.1126/scitranslmed.3001538.

Dhami, P; Bruce, AW; Jim, JH; Dillon, SC; Hall, A; Cooper, JL; ... Vetrie, D; + view all (2010) Genomic Approaches Uncover Increasing Complexities in the Regulatory Landscape at the Human SCL (TAL1) Locus. PLOS ONE , 5 (2) , Article e9059. 10.1371/journal.pone.0009059. Green and gold open access
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Dhami, P; Saffrey, P; Bruce, AW; Dillon, SC; Chiang, K; Bonhoure, N; ... Vetrie, D; + view all (2010) Complex Exon-Intron Marking by Histone Modifications Is Not Determined Solely by Nucleosome Distribution. PLOS ONE , 5 (8) , Article e12339. 10.1371/journal.pone.0012339. Green and gold open access
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Di Leva, G; Gasparini, P; Piovan, C; Ngankeu, A; Garofalo, M; Taccioli, C; ... Croce, CM; + view all (2010) MicroRNA Cluster 221-222 and Estrogen Receptor alpha Interactions in Breast Cancer. J NATL CANCER I , 102 (10) 706 - 721. 10.1093/jnci/djq102.

Ekeowa, UI; Freeke, J; Miranda, E; Gooptu, B; Bush, MF; Pérez, J; ... Lomas, DA; + view all (2010) Defining the mechanism of polymerization in the serpinopathies. Proc Natl Acad Sci U S A , 107 (40) 17146 - 17151. 10.1073/pnas.1004785107.

Evangeli, M; Mughal, K; Porter, JB; (2010) WHICH PSYCHOSOCIAL FACTORS ARE RELATED TO CHELATION ADHERENCE IN THALASSEMIA? A SYSTEMATIC REVIEW. HEMOGLOBIN , 34 (3) 305 - 321. 10.3109/03630269.2010.485080.

Evans, P; Kayyali, R; Hider, RC; Eccleston, J; Porter, JB; (2010) Mechanisms for the shuttling of plasma non-transferrin-bound iron (NTBI) onto deferoxamine by deferiprone. TRANSL RES , 156 (2) 55 - 67. 10.1016/j.trsl.2010.05.002.

Fenton, TR; Gwalter, J; Cramer, R; Gout, IT; (2010) S6K1 is acetylated at lysine 516 in response to growth factor stimulation. BIOCHEM BIOPH RES CO , 398 (3) 400 - 405. 10.1016/j.bbrc.2010.06.081.

Fenton, TR; Gwalter, J; Ericsson, J; Gout, IT; (2010) Histone acetyltransferases interact with and acetylate p70 ribosomal S6 kinases in vitro and in vivo. INT J BIOCHEM CELL B , 42 (2) 359 - 366. 10.1016/j.biocel.2009.11.022.

Fern, LA; Whelan, JS; (2010) Recruitment of adolescents and young adults to cancer clinical trials--international comparisons, barriers, and implications. Semin Oncol , 37 (2) e1 - e8. 10.1053/j.seminoncol.2010.04.002.

Fielding, AK; (2010) How I treat Philadelphia chromosome-positive acute lymphoblastic leukemia. BLOOD , 116 (18) 3409 - 3417. 10.1182/blood-2010-01-242750.

Fischer, U; Leidinger, P; Keller, A; Folarin, A; Keller, R; Graf, N; ... Meese, E; + view all (2010) Amplicons on chromosome 12q13-21 in glioblastoma recurrences. INT J CANCER , 126 (11) 2594 - 2602. 10.1002/ijc.24971.

Fish, R; Pinney, J; Jain, P; Addison, C; Jones, C; Jayawardene, S; ... Hutchison, CA; + view all (2010) The Incidence of Major Hemorrhagic Complications After Renal Biopsies in Patients with Monoclonal Gammopathies. CLIN J AM SOC NEPHRO , 5 (11) 1977 - 1980.

Flanagan, JM; Cocciardi, S; Waddell, N; Johnstone, CN; Marsh, A; Henderson, S; ... kConFab Investigators,; + view all (2010) DNA Methylome of Familial Breast Cancer Identifies Distinct Profiles Defined by Mutation Status. AM J HUM GENET , 86 (3) 420 - 433. 10.1016/j.ajhg.2010.02.008.

Flanagan, JM; Kugler, S; Waddell, N; Johnstone, CN; Marsh, A; Henderson, S; ... Chenevix-Trench, G; + view all (2010) DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status. BREAST CANCER RESEARCH , 12 , Article O4. 10.1186/bcr2495.

Fogo, AB; Bostad, L; Svarstad, E; Cook, WJ; Moll, S; Barbey, F; ... ISGFN,; + view all (2010) Scoring system for renal pathology in Fabry disease: report of the International Study Group of Fabry Nephropathy (ISGFN). NEPHROLOGY DIALYSIS TRANSPLANTATION , 25 (7) 2168 - 2177. 10.1093/ndt/gfp528.

Folarin, AA; Konerding, MA; Timonen, J; Nagl, S; Pedley, RB; (2010) Three-dimensional analysis of tumour vascular corrosion casts using stereoimaging and micro-computed tomography. MICROVASC RES , 80 (1) 89 - 98. 10.1016/j.mvr.2010.03.007.

Forster, MD; Saijo, N; Seymour, L; Calvert, H; (2010) Performing Phase I Clinical Trials of Anticancer Agents: Perspectives from within the European Union and Japan. CLIN CANCER RES , 16 (6) 1737 - 1744. 10.1158/1078-0432.CCR-09-2228.

Foukas, LC; Berenjeno, IM; Gray, A; Khwaja, A; Vanhaesebroeck, B; (2010) Activity of any class IA PI3K isoform can sustain cell proliferation and survival. P NATL ACAD SCI USA , 107 (25) 11381 - 11386. 10.1073/pnas.0906461107.

Fox, J; Glasspool, D; Patkar, V; Austin, M; Black, L; South, M; ... Vincent, C; + view all (2010) Delivering clinical decision support services: There is nothing as practical as a good theory. J BIOMED INFORM , 43 (5) 831 - 843. 10.1016/j.jbi.2010.06.002.

Franks, A; Tronrud, C; Kiakos, K; Kluza, J; Munde, M; Brown, T; ... Lee, M; + view all (2010) Targeting the ICB2 site of the topoisomerase II alpha promoter with a formamido-pyrrole-imidazole-pyrrole H-pin polyamide. BIOORGAN MED CHEM , 18 (15) 5553 - 5561. 10.1016/j.bmc.2010.06.041.

Frye, M; Dragoni, I; Chin, SF; Spiteri, I; Kurowski, A; Provenzano, E; ... Watt, FM; + view all (2010) Genomic gain of 5p15 leads to over-expression of Misu (NSUN2) in breast cancer. CANCER LETT , 289 (1) 71 - 80. 10.1016/j.canlet.2009.08.004.

Georgiadis, A; Tschernutter, M; Bainbridge, JWB; Robbie, SJ; McIntosh, J; Nathwani, AC; ... Ali, RR; + view all (2010) AAV-mediated knockdown of Peripherin-2 in vivo using miRNA-based hairpins. GENE THER , 17 (4) 486 - 493. 10.1038/gt.2009.162.

Giest, S; Grace, S; Senegaglia, AC; Pasquini, R; Gonzalo-Daganzo, RM; Fernandez, MN; ... Travers, PJ; + view all (2010) Cytomegalovirus-specific CD8+T cells targeting different HLA/peptide combinations correlate with protection but at different threshold frequencies. BRIT J HAEMATOL , 148 (2) 311 - 322. 10.1111/j.1365-2141.2009.07969.x.

Gisselbrecht, C; Glass, B; Mounier, N; Gill, DS; Linch, DC; Trneny, M; ... Schmitz, N; + view all (2010) Salvage Regimens With Autologous Transplantation for Relapsed Large B-Cell Lymphoma in the Rituximab Era. JOURNAL OF CLINICAL ONCOLOGY , 28 (27) 4184 - 4190. 10.1200/JCO.2010.28.1618.

Green, CL; Koo, KK; Hills, RK; Burnett, AK; Linch, DC; Gale, RE; (2010) Prognostic Significance of CEBPA Mutations in a Large Cohort of Younger Adult Patients With Acute Myeloid Leukemia: Impact of Double CEBPA Mutations and the Interaction With FLT3 and NPM1 Mutations. J CLIN ONCOL , 28 (16) 2739 - 2747. 10.1200/JCO.2009.26.2501.

Hall, IP; Lomas, DA; (2010) The genetics of obstructive lung disease: big is beautiful. Thorax , 65 (9) 760 - 761. 10.1136/thx.2010.147173.

Hampel, SM; Sidibe, A; Gunaratnam, M; Riou, JF; Neidle, S; (2010) Tetrasubstituted naphthalene diimide ligands with selectivity for telomeric G-quadruplexes and cancer cells. Bioorg Med Chem Lett , 20 (22) 6459 - 6463. 10.1016/j.bmcl.2010.09.066.

Hanley, J; Rastegarlari, G; Nathwani, AC; (2010) An introduction to induced pluripotent stem cells. BRIT J HAEMATOL , 151 (1) 16 - 24. 10.1111/j.1365-2141.2010.08296.x.

Hansen, A; Henderson, S; Lagos, D; Nikitenko, L; Coulter, E; Roberts, S; ... Boshoff, C; + view all (2010) KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming. GENE DEV , 24 (2) 195 - 205. 10.1101/gad.553410.

Hartley, JA; Hamaguchi, A; Coffils, M; Martin, CRH; Suggitt, M; Chen, ZZ; ... Howard, PW; + view all (2010) SG2285, a Novel C2-Aryl-Substituted Pyrrolobenzodiazepine Dimer Prodrug That Cross-links DNA and Exerts Highly Potent Antitumor Activity. CANCER RES , 70 (17) 6849 - 6858. 10.1158/0008-5472.CAN-10-0790.

Hasleton, J; Pasquale, F; Garbowski, M; Walker, MJ; Porter, JB; Moon, JC; (2010) Superior Vena Cava Occlusion by Cardiovascular Magnetic Resonance. CIRCULATION , 122 (8) 853 - 853. 10.1161/CIRCULATIONAHA.110.948471.

Hergovich, A; Hemmings, BA; (2010) TAZ-Mediated Crosstalk between Wnt and Hippo Signaling. DEV CELL , 18 (4) 508 - 509. 10.1016/j.devcel.2010.04.003.

Hersh, CP; Pillai, SG; Zhu, G; Lomas, DA; Bakke, P; Gulsvik, A; ... Silverman, EK; + view all (2010) Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene. Am J Respir Crit Care Med , 182 (5) 605 - 613. 10.1164/rccm.200910-1586OC.

Hirani, V; Tabassum, F; Aresu, M; Mindell, J; (2010) Development of New Demi-Span Equations from a Nationally Representative Sample of Adults to Estimate Maximal Adult Height. J NUTR , 140 (8) 1475 - 1480. 10.3945/jn.109.118430.

Howie, AJ; Owen-Casey, MP; (2010) Discrepancies between descriptions and illustrations of colours in Congo red-stained amyloid, and explanation of discrepant colours. Amyloid , 17 (3-4) 109 - 117. 10.3109/13506129.2010.527448.

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file

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Thompson, LH; Whiston, RA; Rakhimov, Y; Taccioli, C; Liu, CG; Croce, C; Metcalfe, SM; (2010) A LIF/Nanog axis is revealed in T lymphocytes that lack MARCH-7, a RINGv E3 ligase that regulates the LIF-receptor. CELL CYCLE , 9 (20) 4213 - 4221. 10.4161/cc.9.20.13543.

Tili, E; Michaille, JJ; Adair, B; Alder, H; Limagne, E; Taccioli, C; ... Croce, CM; + view all (2010) Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD. CARCINOGENESIS , 31 (9) 1561 - 1566. 10.1093/carcin/bgq143.

Tili, E; Michaille, JJ; Liu, CG; Alder, H; Taccioli, C; Volinia, S; ... Croce, CM; + view all (2010) GAM/ZFp/ZNF512B is central to a gene sensor circuitry involving cell-cycle regulators, TGF beta effectors, Drosha and microRNAs with opposite oncogenic potentials. NUCLEIC ACIDS RES , 38 (21) 7673 - 7688. 10.1093/nar/gkq637. Gold open access

Tirabosco, R; Arora, R; Ye, HT; Brunell, C; Halai, D; Flanagan, AM; (2010) Primary Myxoid Liposarcoma of the Ovary in an Adolescent Girl: A Case Report. INT J GYNECOL PATHOL , 29 (3) 256 - 259. 10.1097/PGP.0b013e3181c03fc9.

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Tracey, L; Streck, CJ; Du, Z; Williams, RF; Pfeffer, LM; Nathwani, AC; Davidoff, AM; (2010) NF-kappa B activation mediates resistance to IFN beta in MLL-rearranged acute lymphoblastic leukemia. LEUKEMIA , 24 (4) 806 - 812. 10.1038/leu.2010.2.

Tsai, K-W; Chan, W-C; Hsu, C-N; Lin, W-C; (2010) Sequence features involved in the mechanism of 3' splice junction wobbling. BMC Molecular Biology , 11 , Article 34. 10.1186/1471-2199-11-34. Green and gold open access
file

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Utting, JC; Flanagan, AM; Brandao-Burch, A; Orriss, IR; Arnett, TR; (2010) Hypoxia stimulates osteoclast formation from human peripheral blood. CELL BIOCHEM FUNCT , 28 (5) 374 - 380. 10.1002/cbf.1660.

van Gestel, RA; Rijken, PJ; Surinova, S; O'Flaherty, M; Heck, AJ; Killian, JA; ... Slijper, M; + view all (2010) The influence of the acyl chain composition of cardiolipin on the stability of mitochondrial complexes; an unexpected effect of cardiolipin in alpha-ketoglutarate dehydrogenase and prohibitin complexes. J Proteomics , 73 (4) 806 - 814. 10.1016/j.jprot.2009.11.009.

van Walraven, SM; Nicoloso-de Faveri, G; Axdorph-Nygell, UAI; Douglas, KW; Jones, DA; Lee, SJ; ... Clinical Working Grp,; + view all (2010) Family donor care management: principles and recommendations. BONE MARROW TRANSPL , 45 (8) 1269 - 1273. 10.1038/bmt.2009.354.

Vanrobays, E; Jennings, BH; Ish-Horowicz, D; (2010) Identification and mapping of induced chromosomal deletions using sequence polymorphisms. Biotechniques , 48 (1) 53 - 60. 10.2144/000113348.

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Vassileva, V; (2010) SRAP-new prognostic marker. Nature Reviews Clinical Oncology , 7 (1) 4 - 4. 10.1038/nrclinonc.2009.195.

Vassileva, V; (2010) Targeted therapies: Farletuzumab-promising new agent in ovarian cancer. Nature Reviews Clinical Oncology , 7 (1) 5 - 5. 10.1038/nrclinonc.2009.200.

Vassileva, V; Piquette-Miller, M; (2010) Inflammation: Extinguishing the Fires Within. CLIN PHARMACOL THER , 87 (4) 375 - 379. 10.1038/clpt.2010.10.

Velica, P; Davies, NJ; Rocha, PP; Schrewe, H; Ride, JP; Bunce, CM; (2010) Lack of functional and expression homology between human and mouse aldo-keto reductase 1C enzymes: implications for modelling human cancers (vol 8, pg 121, 2009). MOL CANCER , 9 , Article 21. 10.1186/1476-4598-9-21. Gold open access

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Verbeke, SLJ; Fletcher, CDM; Alberghini, M; Daugaard, S; Flanagan, AM; Parratt, T; ... Bovee, JVMG; + view all (2010) A Reappraisal of Hemangiopericytoma of Bone; Analysis of Cases Reclassified as Synovial Sarcoma and Solitary Fibrous Tumor of Bone. AM J SURG PATHOL , 34 (6) 777 - 783. 10.1097/PAS.0b013e3181dbedf1.

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Vontell, R; Segovia, KN; Betzl, AJ; Mingote, S; Goldring, K; Cartun, RW; Salamone, JD; (2010) Immunocytochemistry Studies of Basal Ganglia Adenosine A(2A) Receptors in Rat and Human Tissue. J HISTOTECHNOL , 33 (1) 41 - 47.

Waldmeier, F; Bruin, GJ; Glaenzel, U; Hazell, K; Sechaud, R; Warrington, S; Porter, JB; (2010) Pharmacokinetics, Metabolism, and Disposition of Deferasirox in beta-Thalassemic Patients with Transfusion-Dependent Iron Overload Who Are at Pharmacokinetic Steady State. DRUG METAB DISPOS , 38 (5) 808 - 816. 10.1124/dmd.109.030833.

Wheatley-Price, P; Blackhall, F; Lee, SM; Ma, C; Ashcroft, L; Jitlal, M; ... Shepherd, FA; + view all (2010) The influence of sex and histology on outcomes in non-small-cell lung cancer: a pooled analysis of five randomized trials. Ann Oncol , 21 (10) 2023 - 2028. 10.1093/annonc/mdq067.

Wild, L; Funes, JM; Boshoff, C; Flanagan, JM; (2010) In vitro transformation of mesenchymal stem cells induces gradual genomic hypomethylation. CARCINOGENESIS , 31 (10) 1854 - 1862. 10.1093/carcin/bgq080.

Williams, RF; Myers, AL; Sims, TL; Ng, CY; Nathwani, AC; Davidoff, AM; (2010) Targeting multiple angiogenic pathways for the treatment of neuroblastoma. JOURNAL OF PEDIATRIC SURGERY , 45 (6) 1103 - 1109. 10.1016/j.jpedsurg.2010.02.073.

Xiang, H; Zhu, JD; Chen, Q; Dai, FY; Li, X; Li, MW; ... Wang, J; + view all (2010) Single base-resolution methylome of the silkworm reveals a sparse epigenomic map. NAT BIOTECHNOL , 28 (5) 516 - U181. 10.1038/nbt.1626.

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Yogev, O; Yogev, O; Singer, E; Shaulian, E; Goldberg, M; Fox, TD; Pines, O; (2010) Fumarase: A Mitochondrial Metabolic Enzyme and a Cytosolic/Nuclear Component of the DNA Damage Response. PLOS BIOL , 8 (3) , Article e1000328. 10.1371/journal.pbio.1000328. Green and gold open access
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Zitvogel, L; Kepp, O; Senovilla, L; Menger, L; Chaput, N; Kroemer, G; (2010) Immunogenic tumor cell death for optimal anticancer therapy: the calreticulin exposure pathway. Clin Cancer Res , 16 (12) 3100 - 3104. 10.1158/1078-0432.CCR-09-2891.

Book

Gray, W; Kocjan, G; (2010) Diagnostic Cytopathology. Expert Consult. (3rd ed.). Churchill Livingstone: UK.

Book chapter

Gunaratnam, M; Neidle, S; (2010) An evaluation cascade for G-quadruplex telomere targeting agents in human cancer cells. In: UNSPECIFIED (303 - 313).

Proceedings paper

Andre, R; Schure, U; Magnusson, A; Lahiri, N; Smith, D; Lowdell, MW; ... Tabrizi, SJ; + view all (2010) MYELOID CELL FUNCTION IN MOUSE MODELS OF HUNTINGTON'S DISEASE. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. A5 - A6).

Bafadhel, M; McKenna, S; Terry, S; Mistry, V; Reid, C; Haldar, P; ... Brightling, CE; + view all (2010) ACUTE EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE: IDENTIFICATION OF PHENOTYPE-SPECIFIC BIOMARKERS AND BIOLOGICAL CLUSTERS. In: THORAX. (pp. A3 - A3).

Brucoli, F; Hawkins, RM; Wells, G; Jenkins, TC; Ellis, T; Kotecha, M; ... Thurston, DE; + view all (2010) A potent PBD-heterocyclic polyamide conjugate targeting an ICB2 transcription factor binding site. In: EJC SUPPLEMENTS. (pp. 168 - 168). PERGAMON-ELSEVIER SCIENCE LTD

Freeman, S; Hills, R; Virgo, P; Couzens, S; Lowdell, MW; McNamara, CJ; ... Bumett, A; + view all (2010) Detection of Immunophenotypic Residual Disease After Induction Therapy Is An Independent Prognostic Factor for Duration of Remission In Older AML Patients Treated Intensively. In: BLOOD. (pp. 1118 - 1119). AMER SOC HEMATOLOGY

Freeman, S; Hills, R; Virgo, P; Couzens, S; Lowdell, MW; McNamara, CJ; ... Burnett, A; + view all (2010) Detection of Immunophenotypic Residual Disease After Induction Therapy Is An Independent Prognostic Factor for Duration of Remission In Older AML Patients Treated Intensively. In: BLOOD. (pp. 1118 - 1119). AMER SOC HEMATOLOGY

Graham, T; Khan, S; Oukrif, D; Green, A; Jankowski, J; Barr, H; ... Wright, N; + view all (2010) Investigating Clonal Dynamics in Barrett's Associated tumorigenesis Using Spatial Maps of Genetic Heterogeneity. In: JOURNAL OF PATHOLOGY. (pp. S9 - S9). JOHN WILEY & SONS LTD

Hughes, D; Malmenas, M; (2010) A predictive severity score for Fabry disease. In: MOLECULAR GENETICS AND METABOLISM. (pp. S21 - S21). ACADEMIC PRESS INC ELSEVIER SCIENCE

Knight, A; Mackinnon, S; Lowdell, MW; (2010) CMV Reactive gamma/delta T Cells Are Equivalent to Their alpha/beta Counterparts In the Lysis of CMV Infected Targets - Potential for Post Transplant Adoptive Immunotherapy. In: BLOOD. (pp. 547 - 547). AMER SOC HEMATOLOGY

Knight, A; Mackinnon, S; Lowdell, MW; (2010) CMV-Reactive gamma/delta T Cells Are Equivalent to Their alpha/beta Counterparts In the Lysis of CMV-Infected Targets - Potential for Post Transplant Adoptive Immunotherapy. In: BLOOD. (pp. 547 - 547). AMER SOC HEMATOLOGY

Kottaridis, PD; North, J; Marden, C; Grace, S; Jide-Banwo, S; Sivakumaran, J; Lowdell, MW; (2010) Human NK cells primed by a tumour cell line can be safely transplanted to haploidentical patients with AML and lead to demonstrable GvL activity and long-term NK chimerism. In: BONE MARROW TRANSPLANTATION. (pp. S67 - S68). NATURE PUBLISHING GROUP

Lawrie, AS; Mackie, IJ; Machin, SJ; Peyvandi, F; (2010) Acquired factor XIII deficiency - an under investigated disorder. In: BRITISH JOURNAL OF HAEMATOLOGY. (pp. 1 - 1). WILEY-BLACKWELL PUBLISHING, INC

Lawrie, AS; Mackie, IJ; Peyvandi, F; Machin, SJ; Peyvandi, F; Scully, MA; (2010) Evaluation of an automated platelet-based assay of von Willebrand ristocetin cofactor activity. In: BRITISH JOURNAL OF HAEMATOLOGY. (pp. 33 - 33). WILEY-BLACKWELL PUBLISHING, INC

Liccardi, G; Hartley, JA; Hochhauser, D; (2010) EGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatment. In: EJC SUPPLEMENTS. (pp. 166 - 166). PERGAMON-ELSEVIER SCIENCE LTD

Mellinas-Gomez, M; Spanswick, VJ; Stell, A; Hartley, JA; Thurston, DE; Baines, S; (2010) Investigation of the effect of the sequence-selective DNA cross-linking agent SJG-136 on canine tumour cells in vitro. In: EJC SUPPLEMENTS. (pp. 91 - 91). PERGAMON-ELSEVIER SCIENCE LTD

Nyon, M-P; Levy, G; Kirkpatrick, J; Ekeowa, U; Lomas, DA; Cabrita, LD; ... Gooptu, B; + view all (2010) USE OF NMR SPECTROSCOPY AND NANOSPRAY MASS SPECTROMETRY TO CHARACTERISE BINDING OF LEAD COMPOUNDS FOR DRUG DESIGN IN alpha 1-ANTITRYPSIN DEFICIENCY. In: THORAX. (pp. A30 - A30).

Nyon, MP; Segu, L; Roussel, B; Kalsheker, N; Lomas, DA; Thalassinos, K; Gooptu, B; (2010) CHARACTERISATION OF A NOVEL "PSEUDO-Z" VARIANT OF alpha 1-ANTITRYPSIN. In: THORAX. (pp. A30 - A30). B M J PUBLISHING GROUP

Patel, BD; Coxson, HO; Camp, PG; Pillai, SG; Agusti, AG; Calverley, PM; ... Lomas, DA; + view all (2010) THE EFFECT OF SMALL AIRWAYS DISEASE AND EMPHYSEMA ON THE ASSOCIATION BETWEEN SMOKING AND LUNG FUNCTION, AND BRONCHODILATOR RESPONSE. In: THORAX. (pp. A52 - A52).

Rashid, ST; Marciniak, SJ; Miranda, E; Alexander, GJ; Lomas, DA; Vallier, L; (2010) USE OF HUMAN INDUCED PLURIPOTENT STEM CELLS (HIPSCS) FOR IN VITRO MODELLING OF LIVER DISEASE. In: HEPATOLOGY. (pp. 424A - 425A).

Samuel, ER; Newton, K; Mackinnon, S; Lowdell, MW; (2010) CMV Reactive T Cells Can Be Isolated From G CSF Mobilised Peripheral Blood Apheresates. In: BLOOD. (pp. 546 - 546). AMER SOC HEMATOLOGY

Samuel, ER; Newton, K; Mackinnon, S; Lowdell, MW; (2010) CMV-Reactive T Cells Can Be Isolated From G-CSF Mobilised Peripheral Blood Apheresates. In: BLOOD. (pp. 546 - 546). AMER SOC HEMATOLOGY

Schure, U; Magnusson, A; Lahiri, N; Andre, R; Rabbanian, S; Lowdell, MW; ... Tabrizi, SJ; + view all (2010) CELLULAR SIGNALLING OF HUMAN MONOCYTES IN HUNTINGTON'S DISEASE. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. A6 - A6).

Thirlwell, C; Eymard, M; Meyer, T; Davidson, B; Teschendorff, A; Beck, S; Caplin, M; (2010) Genome-Wide DNA Methylation Profiling of Pancreatic Neuroendocrine Tumors Identifies Distinct Methylation Profiles and Differentially Methylated Gene Promoter Regions Associated with Low, Medium and High Grade Tumors. In: NEUROENDOCRINOLOGY. (pp. 14 - 14). KARGER

Tolner, B; Vigor, K; Mather, S; Robinson, M; Adams, G; Plueckthun, A; Chester, K; (2010) Anti-HER2 imaging agents for breast cancer imaging. In: BREAST CANCER RESEARCH. (pp. S13 - S13). BIOMED CENTRAL LTD

Thesis

Chaudhry, S.I.; (2010) Analysis of squamous cell carcinoma invasion identifies a role for TRAF6. Doctoral thesis, UCL (University College London). Green open access
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This list was generated on Mon Dec 22 01:23:23 2014 GMT.