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Number of items: 117.

Article

Agusti, A; Calverley, PM; Celli, B; Coxson, HO; Edwards, LD; Lomas, DA; ... Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators,; + view all (2010) Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res , 11 122 - ?. 10.1186/1465-9921-11-122.

Altshuler, D; Durbin, RM; Abecasis, GR; Bentley, DR; Chakravarti, A; Clark, AG; ... Consortium, 1GP; + view all (2010) A map of human genome variation from population-scale sequencing. NATURE , 467 (7319) 1061 - 1073. 10.1038/nature09534.

Andre, R; Schure, U; Magnusson, A; Lahiri, N; Smith, D; Lowdell, MW; ... Tabrizi, SJ; + view all (2010) MYELOID CELL FUNCTION IN MOUSE MODELS OF HUNTINGTON'S DISEASE. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , 81 A5 - A6. 10.1136/jnnp.2010.222570.17.

Azzato, EM; Lee, AJX; Teschendorff, A; Ponder, BAJ; Pharoah, P; Caldas, C; Maia, AT; (2010) Common germ-line polymorphism of C1QA and breast cancer survival. BRIT J CANCER , 102 (8) 1294 - 1299. 10.1038/sj.bjc.6605625.

Bartlett, JMS; Campbell, FM; Ibrahim, M; Thomas, J; Wencyk, P; Ellis, I; ... Miller, K; + view all (2010) A UK NEQAS ICC and ISH multicentre study using the Kreatech Poseidon HER2 FISH probe: intersite variation can be rigorously controlled using FISH. HISTOPATHOLOGY , 56 (3) 297 - 304. 10.1111/j.1365-2559.2010.03493.x.

Beck, S; (2010) A-Z of methylome analysis Introduction. METHODS , 52 (3) 201 - 202. 10.1016/j.ymeth.2010.10.003.

Bell, CG; Finer, S; Lindgren, CM; Wilson, GA; Rakyan, VK; Teschendorff, AE; ... Int Type 2 Diabet 1q Consortium,; + view all (2010) Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus. PLOS ONE , 5 (11) , Article e14040. 10.1371/journal.pone.0014040. Green and gold open access
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Bell, CG; Teschendorff, AE; Rakyan, VK; Maxwell, AP; Beck, S; Savage, DA; (2010) Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus. BMC Medical Genomics , 3 , Article 33. 10.1186/1755-8794-3-33. Green and gold open access
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Belorgey, D; Hägglöf, P; Onda, M; Lomas, DA; (2010) pH-dependent stability of neuroserpin is mediated by histidines 119 and 138; implications for the control of beta-sheet A and polymerization. Protein Sci , 19 (2) 220 - 228. 10.1002/pro.299.

Betts-Henderson, J; Bartesaghi, S; Crosier, M; Lindsay, S; Chen, HL; Salomoni, P; ... Nicotera, P; + view all (2010) The nystagmus-associated FRMD7 gene regulates neuronal outgrowth and development. HUM MOL GENET , 19 (2) 342 - 351. 10.1093/hmg/ddp500.

Bjedov, I; Toivonen, JM; Kerr, F; Slack, C; Jacobson, J; Foley, A; Partridge, L; (2010) Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster. Cell Metabolism , 11 (1) 35 - 46. 10.1016/j.cmet.2009.11.010. Green and gold open access
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Braconi, C; Valeri, N; Gasparini, P; Huang, NY; Taccioli, C; Nuovo, G; ... Patel, T; + view all (2010) Hepatitis C Virus Proteins Modulate MicroRNA Expression and Chemosensitivity in Malignant Hepatocytes. CLIN CANCER RES , 16 (3) 957 - 966. 10.1158/1078-0432.CCR-09-2123.

Brada, M; Stenning, S; Gabe, R; Thompson, LC; Levy, D; Rampling, R; ... Lee, SM; + view all (2010) Temozolomide Versus Procarbazine, Lomustine, and Vincristine in Recurrent High-Grade Glioma. JOURNAL OF CLINICAL ONCOLOGY , 28 (30) 4601 - 4608. 10.1200/JCO.2009.27.1932.

Branchini, BR; Ablamsky, DM; Davis, AL; Southworth, TL; Butler, B; Fan, F; ... Pule, MA; + view all (2010) Red-emitting luciferases for bioluminescence reporter and imaging applications. ANAL BIOCHEM , 396 (2) 290 - 297. 10.1016/j.ab.2009.09.009.

Brooks, SP; Coccia, M; Tang, HR; Kanuga, N; Machesky, LM; Bailly, M; ... Hardcastle, AJ; + view all (2010) The Nance-Horan syndrome protein encodes a functional WAVE homology domain (WHD) and is important for co-ordinating actin remodelling and maintaining cell morphology. HUM MOL GENET , 19 (12) 2421 - 2432. 10.1093/hmg/ddq125.

Brorsson, A-C; Kumita, JR; MacLeod, I; Bolognesi, B; Speretta, E; Luheshi, LM; ... Crowther, DC; + view all (2010) Methods and models in neurodegenerative and systemic protein aggregation diseases. FRONTIERS IN BIOSCIENCE-LANDMARK , 15 373 - 396.

Brorsson, AC; Bolognesi, B; Tartaglia, GG; Shammas, SL; Favrin, G; Watson, I; ... Luheshi, LM; + view all (2010) Intrinsic determinants of neurotoxic aggregate formation by the amyloid beta peptide. Biophys J , 98 (8) 1677 - 1684. 10.1016/j.bpj.2009.12.4320.

Butcher, LM; Beck, S; (2010) AutoMeDIP-seq: A high-throughput, whole genome, DNA methylation assay. METHODS , 52 (3) 223 - 231. 10.1016/j.ymeth.2010.04.003. Gold open access

Cappellini, MD; Porter, J; El-Beshlawy, A; Li, CK; Seymour, JF; Elalfy, M; ... EPIC Study Investigators,; + view all (2010) Tailoring iron chelation by iron intake and serum ferritin: the prospective EPIC study of deferasirox in 1744 patients with transfusion-dependent anemias. HAEMATOL-HEMATOL J , 95 (4) 557 - 566. 10.3324/haematol.2009.014696. Gold open access

Castleton, AZ; Brazma, D; Howard-Reeves, J; Chanalaris, A; Glanville, J; Nizetic, D; ... Nacheva, EP; + view all (2010) Genome gains at chromosome 21q21/22 segment leads to co-amplification of Down Syndrome Critical Regions and known oncogenes in a case of donor cell-derived acute myeloid leukaemia following allogeneic sex mismatched umbilical cord blood transplantation for chronic myeloid leukaemia. BRIT J HAEMATOL , 151 (3) 285 - 288. 10.1111/j.1365-2141.2010.08350.x.

Chavda, S; Babu, B; Yanow, SK; Jardim, A; Spithill, TW; Kiakos, K; ... Lee, M; + view all (2010) A novel achiral seco-cyclopropylpyrido[e]indolone (CPyI) analog of CC-1065 and the duocarmycins: Synthesis, DNA interactions, in vivo anticancer and anti-parasitic evaluation. BIOORGAN MED CHEM , 18 (14) 5016 - 5024. 10.1016/j.bmc.2010.05.078.

Chilvers, ER; Lomas, DA; (2010) Diagnosing COPD in non-smokers: splitting not lumping. Thorax , 65 (6) 465 - 466. 10.1136/thx.2009.128421.

Cho, MH; Boutaoui, N; Klanderman, BJ; Sylvia, JS; Ziniti, JP; Hersh, CP; ... Silverman, EK; + view all (2010) Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat Genet , 42 (3) 200 - 202. 10.1038/ng.535.

Cohen, H; Machin, SJ; (2010) Antithrombotic treatment failures in antiphospholipid syndrome: the new anticoagulants? LUPUS , 19 (4) 486 - 491. 10.1177/0961203310361355.

Dhami, P; Saffrey, P; Bruce, AW; Dillon, SC; Chiang, K; Bonhoure, N; ... Vetrie, D; + view all (2010) Complex Exon-Intron Marking by Histone Modifications Is Not Determined Solely by Nucleosome Distribution. PLOS ONE , 5 (8) , Article e12339. 10.1371/journal.pone.0012339. Green and gold open access
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Di Leva, G; Gasparini, P; Piovan, C; Ngankeu, A; Garofalo, M; Taccioli, C; ... Croce, CM; + view all (2010) MicroRNA Cluster 221-222 and Estrogen Receptor alpha Interactions in Breast Cancer. J NATL CANCER I , 102 (10) 706 - 721. 10.1093/jnci/djq102.

Ekeowa, UI; Freeke, J; Miranda, E; Gooptu, B; Bush, MF; Pérez, J; ... Lomas, DA; + view all (2010) Defining the mechanism of polymerization in the serpinopathies. Proc Natl Acad Sci U S A , 107 (40) 17146 - 17151. 10.1073/pnas.1004785107.

Evans, P; Kayyali, R; Hider, RC; Eccleston, J; Porter, JB; (2010) Mechanisms for the shuttling of plasma non-transferrin-bound iron (NTBI) onto deferoxamine by deferiprone. TRANSL RES , 156 (2) 55 - 67. 10.1016/j.trsl.2010.05.002.

Fenton, TR; Gwalter, J; Cramer, R; Gout, IT; (2010) S6K1 is acetylated at lysine 516 in response to growth factor stimulation. BIOCHEM BIOPH RES CO , 398 (3) 400 - 405. 10.1016/j.bbrc.2010.06.081.

Fielding, AK; (2010) How I treat Philadelphia chromosome-positive acute lymphoblastic leukemia. BLOOD , 116 (18) 3409 - 3417. 10.1182/blood-2010-01-242750.

Fish, R; Pinney, J; Jain, P; Addison, C; Jones, C; Jayawardene, S; ... Hutchison, CA; + view all (2010) The Incidence of Major Hemorrhagic Complications After Renal Biopsies in Patients with Monoclonal Gammopathies. CLIN J AM SOC NEPHRO , 5 (11) 1977 - 1980.

Fogo, AB; Bostad, L; Svarstad, E; Cook, WJ; Moll, S; Barbey, F; ... ISGFN,; + view all (2010) Scoring system for renal pathology in Fabry disease: report of the International Study Group of Fabry Nephropathy (ISGFN). NEPHROLOGY DIALYSIS TRANSPLANTATION , 25 (7) 2168 - 2177. 10.1093/ndt/gfp528.

Franks, A; Tronrud, C; Kiakos, K; Kluza, J; Munde, M; Brown, T; ... Lee, M; + view all (2010) Targeting the ICB2 site of the topoisomerase II alpha promoter with a formamido-pyrrole-imidazole-pyrrole H-pin polyamide. BIOORGAN MED CHEM , 18 (15) 5553 - 5561. 10.1016/j.bmc.2010.06.041.

Frye, M; Dragoni, I; Chin, SF; Spiteri, I; Kurowski, A; Provenzano, E; ... Watt, FM; + view all (2010) Genomic gain of 5p15 leads to over-expression of Misu (NSUN2) in breast cancer. CANCER LETT , 289 (1) 71 - 80. 10.1016/j.canlet.2009.08.004.

Georgiadis, A; Tschernutter, M; Bainbridge, JWB; Robbie, SJ; McIntosh, J; Nathwani, AC; ... Ali, RR; + view all (2010) AAV-mediated knockdown of Peripherin-2 in vivo using miRNA-based hairpins. GENE THER , 17 (4) 486 - 493. 10.1038/gt.2009.162.

Gisselbrecht, C; Glass, B; Mounier, N; Gill, DS; Linch, DC; Trneny, M; ... Schmitz, N; + view all (2010) Salvage Regimens With Autologous Transplantation for Relapsed Large B-Cell Lymphoma in the Rituximab Era. JOURNAL OF CLINICAL ONCOLOGY , 28 (27) 4184 - 4190. 10.1200/JCO.2010.28.1618.

Green, CL; Koo, KK; Hills, RK; Burnett, AK; Linch, DC; Gale, RE; (2010) Prognostic Significance of CEBPA Mutations in a Large Cohort of Younger Adult Patients With Acute Myeloid Leukemia: Impact of Double CEBPA Mutations and the Interaction With FLT3 and NPM1 Mutations. J CLIN ONCOL , 28 (16) 2739 - 2747. 10.1200/JCO.2009.26.2501.

Hall, IP; Lomas, DA; (2010) The genetics of obstructive lung disease: big is beautiful. Thorax , 65 (9) 760 - 761. 10.1136/thx.2010.147173.

Hansen, A; Henderson, S; Lagos, D; Nikitenko, L; Coulter, E; Roberts, S; ... Boshoff, C; + view all (2010) KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming. GENE DEV , 24 (2) 195 - 205. 10.1101/gad.553410.

Hersh, CP; Pillai, SG; Zhu, G; Lomas, DA; Bakke, P; Gulsvik, A; ... Silverman, EK; + view all (2010) Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene. Am J Respir Crit Care Med , 182 (5) 605 - 613. 10.1164/rccm.200910-1586OC.

Hirani, V; Tabassum, F; Aresu, M; Mindell, J; (2010) Development of New Demi-Span Equations from a Nationally Representative Sample of Adults to Estimate Maximal Adult Height. J NUTR , 140 (8) 1475 - 1480. 10.3945/jn.109.118430.

Illingworth, C; Pirmadjid, N; Serhal, P; Howe, K; FitzHarris, G; (2010) MCAK regulates chromosome alignment but is not necessary for preventing aneuploidy in mouse oocyte meiosis I. DEVELOPMENT , 137 (13) 2133 - 2138. 10.1242/dev.048306.

Jacques, TS; Swales, A; Brzozowski, MJ; Henriquez, NV; Linehan, JM; Mirzadeh, Z; ... Brandner, S; + view all (2010) Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes. EMBO J , 29 (1) 222 - 235. 10.1038/emboj.2009.327. Gold open access

Landeira, D; Sauer, S; Poot, R; Dvorkina, M; Mazzarella, L; Jorgensen, HF; ... Fisher, AG; + view all (2010) Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators. NAT CELL BIOL , 12 (6) 618 - U214. 10.1038/ncb2065.

Lawson, ARJ; Tatevossian, RG; Phipps, KP; Picker, SR; Michalski, A; Sheer, D; ... Forshew, T; + view all (2010) RAF gene fusions are specific to pilocytic astrocytoma in a broad paediatric brain tumour cohort. ACTA NEUROPATHOL , 120 (2) 271 - 273. 10.1007/s00401-010-0693-y.

Lechner, M; Boshoff, C; Beck, S; (2010) Cancer Epigenome. EPIGENETICS AND CANCER, PT A , 70 247 - 276. 10.1016/S0065-2660(10)70009-2.

Ledermann, JA; Kristeleit, RS; (2010) Optimal treatment for relapsing ovarian cancer. ANN ONCOL , 21 218 - 222. 10.1093/annonc/mdq377.

Lee, JW; Yoon, SS; Shen, ZXA; Ganser, A; Hsu, HC; Habr, D; ... Epic Study Investigators,; + view all (2010) Iron chelation therapy with deferasirox in patients with aplastic anemia: a subgroup analysis of 116 patients from the EPIC trial. BLOOD , 116 (14) 2448 - 2454. 10.1182/blood-2010-01-261289.

Li, N; Ye, MZ; Li, YR; Yan, ZX; Butcher, LM; Sun, JH; ... Wang, J; + view all (2010) Whole genome DNA methylation analysis based on high throughput sequencing technology. METHODS , 52 (3) 203 - 212. 10.1016/j.ymeth.2010.04.009.

Li, YR; Zhu, JD; Tian, G; Li, N; Li, QB; Ye, MZ; ... Zhang, XQ; + view all (2010) The DNA Methylome of Human Peripheral Blood Mononuclear Cells. PLoS Biology , 8 (11) , Article e1000533. 10.1371/journal.pbio.1000533. Green and gold open access
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Lomas, DA; (2010) 25th anniversary Transatlantic Airway Conference: Protein misfolding and obstructive lung disease. Proc Am Thorac Soc , 7 (6) 343 - 345. 10.1513/pats.201001-018AW.

Luheshi, LM; Hoyer, W; de Barros, TP; van Dijk Härd, I; Brorsson, AC; Macao, B; ... Härd, T; + view all (2010) Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo. PLoS Biology , 8 (3) , Article e1000334 . 10.1371/journal.pbio.1000334. Green and gold open access
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Malzer, E; Daly, ML; Moloney, A; Sendall, TJ; Thomas, SE; Ryder, E; ... Marciniak, SJ; + view all (2010) Impaired tissue growth is mediated by checkpoint kinase 1 (CHK1) in the integrated stress response. J Cell Sci , 123 (Pt 17) 2892 - 2900. 10.1242/jcs.070078.

Marciniak, SJ; Lomas, DA; (2010) Alpha1-antitrypsin deficiency and autophagy. N Engl J Med , 363 (19) 1863 - 1864. 10.1056/NEJMcibr1008007.

McGee, MC; Hamner, JB; Williams, RF; Rosati, SF; Sims, TL; Ng, CY; ... Davidoff, AM; + view all (2010) IMPROVED INTRATUMORAL OXYGENATION THROUGH VASCULAR NORMALIZATION INCREASES GLIOMA SENSITIVITY TO IONIZING RADIATION. INT J RADIAT ONCOL , 76 (5) 1537 - 1545. 10.1016/j.ijrobp.2009.12.010.

Mednick, L; Yu, SL; Trachtenberg, F; Xu, Y; Kleinert, DA; Giardina, PJ; ... Thalassemia Clinical Res Network,; + view all (2010) Symptoms of depression and anxiety in patients with thalassemia: Prevalence and correlates in the thalassemia longitudinal cohort. AM J HEMATOL , 85 (10) 802 - 805. 10.1002/ajh.21826.

Mesri, EA; Cesarman, E; Boshoff, C; (2010) Kaposi's sarcoma and its associated herpesvirus. NAT REV CANCER , 10 (10) 707 - 719. 10.1038/nrc2888.

Miranda, E; Pérez, J; Ekeowa, UI; Hadzic, N; Kalsheker, N; Gooptu, B; ... Lomas, DA; + view all (2010) A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with alpha1-antitrypsin deficiency. Hepatology , 52 (3) 1078 - 1088. 10.1002/hep.23760.

Molife, LR; Fong, PC; Paccagnella, L; Reid, AH; Shaw, HM; Vidal, L; ... de Bono, JS; + view all (2010) The insulin-like growth factor-I receptor inhibitor figitumumab (CP-751,871) in combination with docetaxel in patients with advanced solid tumours: results of a phase Ib dose-escalation, open-label study. Br J Cancer , 103 (3) 332 - 339. 10.1038/sj.bjc.6605767.

Moogk, D; Stewart, M; Gamble, D; Bhatia, M; Jervis, E; (2010) Human ESC Colony Formation Is Dependent on Interplay Between Self-Renewing hESCs and Unique Precursors Responsible for Niche Generation. CYTOMETRY PART A , 77A (4) 321 - 327. 10.1002/cyto.a.20878.

Munuswamy-Ramanujam, G; Dai, E; Liu, L; Shnabel, M; Sun, YM; Bartee, M; ... Lucas, AR; + view all (2010) Neuroserpin, a thrombolytic serine protease inhibitor (serpin), blocks transplant vasculopathy with associated modification of T-helper cell subsets. Thromb Haemost , 103 (3) 545 - 555. 10.1160/TH09-07-0441.

Northover, J; Glynne-Jones, R; Sebag-Montefiore, D; James, R; Meadows, H; Wan, S; ... Ledermann, J; + view all (2010) Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I). BRIT J CANCER , 102 (7) 1123 - 1128. 10.1038/sj.bjc.6605605.

Novakovic, B; Wong, NC; Sibson, M; Ng, HK; Morley, R; Manuelpillai, U; ... Saffery, R; + view all (2010) DNA Methylation-mediated Down-regulation of DNA Methyltransferase-1 (DNMT1) Is Coincident with, but Not Essential for, Global Hypomethylation in Human Placenta. J BIOL CHEM , 285 (13) 9583 - 9593. 10.1074/jbc.M109.064956. Gold open access

Nutt, JE; Razak, ARA; O'Toole, K; Black, F; Quinn, AE; Calvert, AH; ... Lunec, J; + view all (2010) The role of folate receptor alpha (FR alpha) in the response of malignant pleural mesothelioma to pemetrexed-containing chemotherapy. BRIT J CANCER , 102 (3) 553 - 560. 10.1038/sj.bjc.6605501.

Ooi, SKT; Wolf, D; Hartung, O; Agarwal, S; Daley, GQ; Goff, SP; Bestor, TH; (2010) Dynamic instability of genomic methylation patterns in pluripotent stem cells. EPIGENET CHROMATIN , 3 , Article 17. 10.1186/1756-8935-3-17. Gold open access

Patel, B; Rai, L; Buck, G; Richards, SM; Mortuza, Y; Mitchell, W; ... Foroni, L; + view all (2010) Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: final results of the international trial UKALL XII/ECOG2993. BRIT J HAEMATOL , 148 (1) 80 - 89. 10.1111/j.1365-2141.2009.07941.x.

Peggs, KS; Quezada, SA; (2010) Ipilimumab attenuation of an inhibitory immune checkpoint improves survival in metastatic melanoma. EXPERT REV ANTICANC , 10 (11) 1697 - 1701. 10.1586/ERA.10.144.

Pennell, DJ; Porter, JB; Cappellini, MD; El-Beshlawy, A; Chan, LL; Aydinok, Y; ... Taher, A; + view all (2010) Efficacy of deferasirox in reducing and preventing cardiac iron overload in beta-thalassemia. BLOOD , 115 (12) 2364 - 2371. 10.1182/blood-2009-04-217455.

Pichiorri, F; Suh, SS; Rocci, A; De Luca, L; Taccioli, C; Santhanam, R; ... Croce, CM; + view all (2010) Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development. CANCER CELL , 18 (4) 367 - 381. 10.1016/j.ccr.2010.09.005.

Pillai, SG; Kong, X; Edwards, LD; Cho, MH; Anderson, WH; Coxson, HO; ... ECLIPSE and ICGN Investigators,; + view all (2010) Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease. Am J Respir Crit Care Med , 182 (12) 1498 - 1505. 10.1164/rccm.201002-0151OC.

Porter, DL; Alyea, EP; Antin, JH; DeLima, M; Estey, E; Falkenburg, JHF; ... van Besien, K; + view all (2010) NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation. BIOL BLOOD MARROW TR , 16 (11) 1467 - 1503. 10.1016/j.bbmt.2010.08.001.

Porter, JB; (2010) Deferasirox-current knowledge and future challenges. COOLEY'S ANEMIA: NINTH SYMPOSIUM , 1202 87 - 93. 10.1111/j.1749-6632.2010.05582.x.

Quezada, SA; Simpson, TR; Peggs, KS; Merghoub, T; Vider, J; Fan, XZ; ... Allison, JP; + view all (2010) Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts. J EXP MED , 207 (3) 637 - 650. 10.1084/jem.20091918.

Rashid, ST; Corbineau, S; Hannan, N; Marciniak, SJ; Miranda, E; Alexander, G; ... Vallier, L; + view all (2010) Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. J Clin Invest , 120 (9) 3127 - 3136. 10.1172/JCI43122.

Russnes, HG; Vollan, HKM; Lingjaerde, OC; Krasnitz, A; Lundin, P; Naume, B; ... Borresen-Dale, AL; + view all (2010) Genomic Architecture Characterizes Tumor Progression Paths and Fate in Breast Cancer Patients. SCI TRANSL MED , 2 (38) , Article 38ra47. 10.1126/scitranslmed.3000611.

Salomoni, P; Calegari, F; (2010) Cell cycle control of mammalian neural stem cells: putting a speed limit on G1. TRENDS CELL BIOL , 20 (5) 233 - 243. 10.1016/j.tcb.2010.01.006.

Samarasinghe, S; Mancao, C; Pule, M; Nawroly, N; Karlsson, H; Brewin, J; ... Amrolia, PJ; + view all (2010) Functional characterization of alloreactive T cells identifies CD25 and CD71 as optimal targets for a clinically applicable allodepletion strategy. BLOOD , 115 (2) 396 - 407. 10.1182/blood-2009-08-235895.

Sørheim, IC; Bakke, P; Gulsvik, A; Pillai, SG; Johannessen, A; Gaarder, PI; ... Silverman, EK; + view all (2010) α₁-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts. Chest , 138 (5) 1125 - 1132. 10.1378/chest.10-0746.

Sørheim, IC; DeMeo, DL; Washko, G; Litonjua, A; Sparrow, D; Bowler, R; ... International COPD Genetics Network Investigators,; + view all (2010) Polymorphisms in the superoxide dismutase-3 gene are associated with emphysema in COPD. COPD , 7 (4) 262 - 268. 10.3109/15412555.2010.496821.

Schure, U; Magnusson, A; Lahiri, N; Andre, R; Rabbanian, S; Lowdell, MW; ... Tabrizi, SJ; + view all (2010) CELLULAR SIGNALLING OF HUMAN MONOCYTES IN HUNTINGTON'S DISEASE. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , 81 (1) A6 - A6. 10.1136/jnnp.2010.222570.18.

Shaw, BE; Arguello, R; Garcia-Sepulveda, CA; Madrigal, JA; (2010) The impact of HLA genotyping on survival following unrelated donor haematopoietic stem cell transplantation. BRIT J HAEMATOL , 150 (3) 251 - 258. 10.1111/j.1365-2141.2010.08224.x.

Shaw, BE; Ball, L; Beksac, M; Bengtsson, M; Confer, D; Diler, S; ... WMDA,; + view all (2010) Donor safety: the role of the WMDA in ensuring the safety of volunteer unrelated donors: clinical and ethical considerations. BONE MARROW TRANSPL , 45 (5) 832 - 838. 10.1038/bmt.2010.2.

Shaw, BE; Mayor, NP; Russell, NH; Apperley, JF; Clark, RE; Cornish, J; ... Madrigal, JA; + view all (2010) Diverging effects of HLA-DPB1 matching status on outcome following unrelated donor transplantation depending on disease stage and the degree of matching for other HLA alleles. LEUKEMIA , 24 (1) 58 - 65. 10.1038/leu.2009.239.

Simpson, TR; Quezada, SA; Allison, JP; (2010) Regulation of CD4 T cell activation and effector function by inducible costimulator (ICOS). CURR OPIN IMMUNOL , 22 (3) 326 - 332. 10.1016/j.coi.2010.01.001.

Speyer, BE; Pizzey, AR; Ranieri, M; Joshi, R; Delhanty, JD; Serhal, P; (2010) Fall in implantation rates following ICSI with sperm with high DNA fragmentation. Hum Reprod , 25 (7) 1609 - 1618. 10.1093/humrep/deq116.

Steele, AJ; Prentice, AG; Cwynarski, K; Hoffbrand, AV; Hart, SM; Lowdell, MW; ... Wickremasinghe, RG; + view all (2010) The JAK3-selective inhibitor PF-956980 reverses the resistance to cytotoxic agents induced by interleukin-4 treatment of chronic lymphocytic leukemia cells: potential for reversal of cytoprotection by the microenvironment. BLOOD , 116 (22) 4569 - 4577. 10.1182/blood-2009-09-245811.

Taylor, RM; Franck, LS; Dhawan, A; Gibson, F; (2010) The Stories of Young People Living With a Liver Transplant. QUAL HEALTH RES , 20 (8) 1076 - 1090. 10.1177/1049732310368405.

Teschendorff, AE; Gomez, S; Arenas, A; El-Ashry, D; Schmidt, M; Gehrmann, M; Caldas, C; (2010) Improved prognostic classification of breast cancer defined by antagonistic activation patterns of immune response pathway modules. BMC Cancer , 10 , Article 604. 10.1186/1471-2407-10-604. Green and gold open access
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Teschendorff, AE; Jiao, Y; Caldas, C; (2010) Prognostic gene network modules in breast cancer hold promise. BREAST CANCER RES , 12 (6) , Article 317. 10.1186/bcr2774.

Teschendorff, AE; Menon, U; Gentry-Maharaj, A; Ramus, SJ; Weisenberger, DJ; Shen, H; ... Widschwendter, M; + view all (2010) Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. GENOME RES , 20 (4) 440 - 446. 10.1101/gr.103606.109.

Teschendorff, AE; Severini, S; (2010) Increased entropy of signal transduction in the cancer metastasis phenotype. BMC Systems Biology , 4 , Article 104. 10.1186/1752-0509-4-104. Green and gold open access
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Thirlwell, C; Eymard, M; Feber, A; Teschendorff, A; Pearce, K; Lechner, M; ... Beck, S; + view all (2010) Genome-wide DNA methylation analysis of archival formalin-fixed paraffin-embedded tissue using the Illumina Infinium HumanMethylation27 BeadChip. METHODS , 52 (3) 248 - 254. 10.1016/j.ymeth.2010.04.012.

Thirlwell, C; Will, OCC; Domingo, E; Graham, TA; McDonald, SAC; Oukrif, D; ... Leedham, SJ; + view all (2010) Clonality Assessment and Clonal Ordering of Individual Neoplastic Crypts Shows Polyclonality of Colorectal Adenomas. GASTROENTEROLOGY , 138 (4) 1441 - U298. 10.1053/j.gastro.2010.01.033.

Udler, MS; Ahmed, S; Healey, CS; Meyer, K; Struewing, J; Maranian, M; ... Dunning, AM; + view all (2010) Fine scale mapping of the breast cancer 16q12 locus. HUM MOL GENET , 19 (12) 2507 - 2515. 10.1093/hmg/ddq122.

Ueda, T; Volinia, S; Okumura, H; Shimizu, M; Taccioli, C; Rossi, S; ... Croce, CM; + view all (2010) Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis. LANCET ONCOL , 11 (2) 136 - 146. 10.1016/S1470-2045(09)70343-2.

Utting, JC; Flanagan, AM; Brandao-Burch, A; Orriss, IR; Arnett, TR; (2010) Hypoxia stimulates osteoclast formation from human peripheral blood. CELL BIOCHEM FUNCT , 28 (5) 374 - 380. 10.1002/cbf.1660.

Volinia, S; Galasso, M; Costinean, S; Tagliavini, L; Gamberoni, G; Drusco, A; ... Croce, CM; + view all (2010) Reprogramming of miRNA networks in cancer and leukemia. GENOME RES , 20 (5) 589 - 599. 10.1101/gr.098046.109.

Vontell, R; Segovia, KN; Betzl, AJ; Mingote, S; Goldring, K; Cartun, RW; Salamone, JD; (2010) Immunocytochemistry Studies of Basal Ganglia Adenosine A(2A) Receptors in Rat and Human Tissue. J HISTOTECHNOL , 33 (1) 41 - 47.

Xiang, H; Zhu, JD; Chen, Q; Dai, FY; Li, X; Li, MW; ... Wang, J; + view all (2010) Single base-resolution methylome of the silkworm reveals a sparse epigenomic map. NAT BIOTECHNOL , 28 (5) 516 - U181. 10.1038/nbt.1626.

Yap, TA; Vidal, L; Adam, J; Stephens, P; Spicer, J; Shaw, H; ... Plummer, R; + view all (2010) Phase I Trial of the Irreversible EGFR and HER2 Kinase Inhibitor BIBW 2992 in Patients With Advanced Solid Tumors. J CLIN ONCOL , 28 (25) 3965 - 3972. 10.1200/JCO.2009.26.7278.

Proceedings paper

Andre, R; Schure, U; Magnusson, A; Lahiri, N; Smith, D; Lowdell, MW; ... Tabrizi, SJ; + view all (2010) MYELOID CELL FUNCTION IN MOUSE MODELS OF HUNTINGTON'S DISEASE. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. A5 - A6).

Bafadhel, M; McKenna, S; Terry, S; Mistry, V; Reid, C; Haldar, P; ... Brightling, CE; + view all (2010) ACUTE EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE: IDENTIFICATION OF PHENOTYPE-SPECIFIC BIOMARKERS AND BIOLOGICAL CLUSTERS. In: THORAX. (pp. A3 - A3).

Freeman, S; Hills, R; Virgo, P; Couzens, S; Lowdell, MW; McNamara, CJ; ... Bumett, A; + view all (2010) Detection of Immunophenotypic Residual Disease After Induction Therapy Is An Independent Prognostic Factor for Duration of Remission In Older AML Patients Treated Intensively. In: BLOOD. (pp. 1118 - 1119). AMER SOC HEMATOLOGY

Freeman, S; Hills, R; Virgo, P; Couzens, S; Lowdell, MW; McNamara, CJ; ... Burnett, A; + view all (2010) Detection of Immunophenotypic Residual Disease After Induction Therapy Is An Independent Prognostic Factor for Duration of Remission In Older AML Patients Treated Intensively. In: BLOOD. (pp. 1118 - 1119). AMER SOC HEMATOLOGY

Graham, T; Khan, S; Oukrif, D; Green, A; Jankowski, J; Barr, H; ... Wright, N; + view all (2010) Investigating Clonal Dynamics in Barrett's Associated tumorigenesis Using Spatial Maps of Genetic Heterogeneity. In: JOURNAL OF PATHOLOGY. (pp. S9 - S9). JOHN WILEY & SONS LTD

Knight, A; Mackinnon, S; Lowdell, MW; (2010) CMV Reactive gamma/delta T Cells Are Equivalent to Their alpha/beta Counterparts In the Lysis of CMV Infected Targets - Potential for Post Transplant Adoptive Immunotherapy. In: BLOOD. (pp. 547 - 547). AMER SOC HEMATOLOGY

Knight, A; Mackinnon, S; Lowdell, MW; (2010) CMV-Reactive gamma/delta T Cells Are Equivalent to Their alpha/beta Counterparts In the Lysis of CMV-Infected Targets - Potential for Post Transplant Adoptive Immunotherapy. In: BLOOD. (pp. 547 - 547). AMER SOC HEMATOLOGY

Kottaridis, PD; North, J; Marden, C; Grace, S; Jide-Banwo, S; Sivakumaran, J; Lowdell, MW; (2010) Human NK cells primed by a tumour cell line can be safely transplanted to haploidentical patients with AML and lead to demonstrable GvL activity and long-term NK chimerism. In: BONE MARROW TRANSPLANTATION. (pp. S67 - S68). NATURE PUBLISHING GROUP

Nyon, M-P; Levy, G; Kirkpatrick, J; Ekeowa, U; Lomas, DA; Cabrita, LD; ... Gooptu, B; + view all (2010) USE OF NMR SPECTROSCOPY AND NANOSPRAY MASS SPECTROMETRY TO CHARACTERISE BINDING OF LEAD COMPOUNDS FOR DRUG DESIGN IN alpha 1-ANTITRYPSIN DEFICIENCY. In: THORAX. (pp. A30 - A30).

Nyon, MP; Segu, L; Roussel, B; Kalsheker, N; Lomas, DA; Thalassinos, K; Gooptu, B; (2010) CHARACTERISATION OF A NOVEL "PSEUDO-Z" VARIANT OF alpha 1-ANTITRYPSIN. In: THORAX. (pp. A30 - A30). B M J PUBLISHING GROUP

Patel, BD; Coxson, HO; Camp, PG; Pillai, SG; Agusti, AG; Calverley, PM; ... Lomas, DA; + view all (2010) THE EFFECT OF SMALL AIRWAYS DISEASE AND EMPHYSEMA ON THE ASSOCIATION BETWEEN SMOKING AND LUNG FUNCTION, AND BRONCHODILATOR RESPONSE. In: THORAX. (pp. A52 - A52).

Rashid, ST; Marciniak, SJ; Miranda, E; Alexander, GJ; Lomas, DA; Vallier, L; (2010) USE OF HUMAN INDUCED PLURIPOTENT STEM CELLS (HIPSCS) FOR IN VITRO MODELLING OF LIVER DISEASE. In: HEPATOLOGY. (pp. 424A - 425A).

Samuel, ER; Newton, K; Mackinnon, S; Lowdell, MW; (2010) CMV Reactive T Cells Can Be Isolated From G CSF Mobilised Peripheral Blood Apheresates. In: BLOOD. (pp. 546 - 546). AMER SOC HEMATOLOGY

Samuel, ER; Newton, K; Mackinnon, S; Lowdell, MW; (2010) CMV-Reactive T Cells Can Be Isolated From G-CSF Mobilised Peripheral Blood Apheresates. In: BLOOD. (pp. 546 - 546). AMER SOC HEMATOLOGY

Schure, U; Magnusson, A; Lahiri, N; Andre, R; Rabbanian, S; Lowdell, MW; ... Tabrizi, SJ; + view all (2010) CELLULAR SIGNALLING OF HUMAN MONOCYTES IN HUNTINGTON'S DISEASE. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. A6 - A6).

Thirlwell, C; Eymard, M; Meyer, T; Davidson, B; Teschendorff, A; Beck, S; Caplin, M; (2010) Genome-Wide DNA Methylation Profiling of Pancreatic Neuroendocrine Tumors Identifies Distinct Methylation Profiles and Differentially Methylated Gene Promoter Regions Associated with Low, Medium and High Grade Tumors. In: NEUROENDOCRINOLOGY. (pp. 14 - 14). KARGER

Thesis

Chaudhry, S.I.; (2010) Analysis of squamous cell carcinoma invasion identifies a role for TRAF6. Doctoral thesis, UCL (University College London). Green open access
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This list was generated on Thu Nov 20 06:33:11 2014 GMT.