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Number of items: 73.

A

Adams, D; Altucci, L; Antonarakis, SE; Ballesteros, J; Beck, S; Bird, A; ... Willcocks, S; + view all (2012) BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol , 30 (3) 224 - 226. 10.1038/nbt.2153.

Agbamu, DA; Day, N; Walsh, CJ; Hendrickse, CW; Langman, G; Pallan, A; ... Lees, N; + view all (2012) Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: The pilot phase of a randomised controlled trial. The Lancet Oncology , 13 (11) 1152 - 1160. 10.1016/S1470-2045(12)70348-0. Green and gold open access
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Agustí, A; Edwards, LD; Rennard, SI; MacNee, W; Tal-Singer, R; Miller, BE; ... Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators,; + view all (2012) Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype. PLoS One , 7 (5) , Article e37483. 10.1371/journal.pone.0037483. Green and gold open access
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Albert, P; Agusti, A; Edwards, L; Tal-Singer, R; Yates, J; Bakke, P; ... Calverley, P; + view all (2012) Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease. Thorax , 67 (8) 701 - 708. 10.1136/thoraxjnl-2011-201458.

Aminuddin, F; Akhabir, L; Stefanowicz, D; Paré, PD; Connett, JE; Anthonisen, NR; ... Sandford, AJ; + view all (2012) Genetic association between human chitinases and lung function in COPD. Hum Genet , 131 (7) 1105 - 1114. 10.1007/s00439-011-1127-1.

B

Bafadhel, M; McKenna, S; Terry, S; Mistry, V; Pancholi, M; Venge, P; ... Brightling, CE; + view all (2012) Blood eosinophils to direct corticosteroid treatment of exacerbations of chronic obstructive pulmonary disease: a randomized placebo-controlled trial. Am J Respir Crit Care Med , 186 (1) 48 - 55. 10.1164/rccm.201108-1553OC.

C

Celli, BR; Locantore, N; Yates, J; Tal-Singer, R; Miller, BE; Bakke, P; ... ECLIPSE Investigators,; + view all (2012) Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease. Am J Respir Crit Care Med , 185 (10) 1065 - 1072. 10.1164/rccm.201110-1792OC.

Cho, MH; Castaldi, PJ; Wan, ES; Siedlinski, M; Hersh, CP; Demeo, DL; ... COPDGene Investigators,; + view all (2012) A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Hum Mol Genet , 21 (4) 947 - 957. 10.1093/hmg/ddr524.

D

Dickens, JA; Lomas, DA; (2012) CC-16 as a biomarker in chronic obstructive pulmonary disease. COPD , 9 (5) 574 - 575. 10.3109/15412555.2012.718926.

Dobricic, V; Stefanova, E; Jankovic, M; Gurunlian, N; Novakovic, I; Hardy, J; ... Guerreiro, R; + view all (2012) Genetic testing in familial and young-onset Alzheimer's disease: mutation spectrum in a Serbian cohort. Neurobiol Aging , 33 (7) 1481.e7 - 1481.12. 10.1016/j.neurobiolaging.2011.12.007.

Dunlop, MG; Dobbins, SE; Farrington, SM; Jones, AM; Palles, C; Whiffin, N; ... Houlston, RS; + view all (2012) Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Nat Genet , 44 (7) 770 - 776. 10.1038/ng.2293.

E

ENCODE Project Consortium,; (2012) An integrated encyclopedia of DNA elements in the human genome. Nature , 489 (7414) 57 - 74. 10.1038/nature11247.

F

Falchook, GS; Kurzrock, R; Kim, KB; Long, GV; Kefford, RF; Arkenau, TH; ... Ouellet, D; + view all (2012) Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: A phase 1 dose-escalation trial. The Lancet , 379 (9829) 1893 - 1901. 10.1016/S0140-6736(12)60398-5.

Fenton, TR; Nathanson, D; Ponte de Albuquerque, C; Kuga, D; Iwanami, A; Dang, J; ... Furnari, FB; + view all (2012) Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240. Proc Natl Acad Sci U S A , 109 (35) 14164 - 14169. 10.1073/pnas.1211962109.

Fernandez, AF; Assenov, Y; Martin-Subero, JI; Balint, B; Siebert, R; Taniguchi, H; ... Esteller, M; + view all (2012) A DNA methylation fingerprint of 1628 human samples. Genome Res , 22 (2) 407 - 419. 10.1101/gr.119867.110.

Fishman, J; Ansari, T; Sibbons, P; Lowdell, M; De Coppi, P; Birchall, M; (2012) Characterisation and immunogenicity of a decellularised skeletal muscle scaffold for laryngeal tissue engineering. In: JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE. (pp. 174 - 174).

Fizazi, K; Scher, HI; Molina, A; Logothetis, CJ; Chi, KN; Jones, RJ; ... COU-AA-301 Investigators,; + view all (2012) Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study. Lancet Oncol , 13 (10) 983 - 992. 10.1016/S1470-2045(12)70379-0.

Fleischhauer, K; Shaw, BE; Madrigal, JA; Gooley, T; Malkki, M; Bardy, P; ... Velardi, A; + view all (2012) Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: A retrospective study. The Lancet Oncology , 13 (4) 366 - 374. 10.1016/S1470-2045(12)70004-9.

G

Gerlinger, M; Rowan, AJ; Horswell, S; Larkin, J; Endesfelder, D; Gronroos, E; ... Swanton, C; + view all (2012) Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med , 366 (10) 883 - 892. 10.1056/NEJMoa1113205.

Gisselbrecht, C; Schmitz, N; Mounier, N; Singh Gill, D; Linch, DC; Trneny, M; ... Glass, B; + view all (2012) Rituximab maintenance therapy after autologous stem-cell transplantation in patients with relapsed CD20(+) diffuse large B-cell lymphoma: final analysis of the collaborative trial in relapsed aggressive lymphoma. J Clin Oncol , 30 (36) 4462 - 4469. 10.1200/JCO.2012.41.9416.

Guerreiro, RJ; Lohmann, E; Kinsella, E; Brás, JM; Luu, N; Gurunlian, N; ... Singleton, A; + view all (2012) Exome sequencing reveals an unexpected genetic cause of disease: NOTCH3 mutation in a Turkish family with Alzheimer's disease. Neurobiol Aging , 33 (5) 1008.e17 - 1008.e23. 10.1016/j.neurobiolaging.2011.10.009.

J

Jagroop-Dearing, I.A.; (2012) Effect of antithrombotic drugs on platelet function and receptors and an investigation into platelet cholesterol. Doctoral thesis, UCL (University College London). Green open access
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Jenkinson, S; Koo, K; Goulden, N; Vora, A; Mitchell, C; Wade, R; ... Gale, RE; + view all (2012) Presence of mutations in the NOTCH1 signalling pathway has a beneficial impact on outcome in paediatric T-ALL patients treated on the MRC UKALL2003 trial. In: BRITISH JOURNAL OF HAEMATOLOGY. (pp. 19 - 20).

Jitlal, M; Khan, I; Lee, SM; Hackshaw, A; (2012) Stopping clinical trials early for futility: retrospective analysis of several randomised clinical studies. British Journal of Cancer , 107 (6) 910 - 917. 10.1038/bjc.2012.344. Green and gold open access
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K

Keeling, D; Mackie, I; Moore, GW; Greer, IA; Greaves, M; Haematology, BCS; (2012) Guidelines on the investigation and management of antiphospholipid syndrome. BRITISH JOURNAL OF HAEMATOLOGY , 157 (1) 47 - 58. 10.1111/j.1365-2141.2012.09037.x.

Kim, DK; Cho, MH; Hersh, CP; Lomas, DA; Miller, BE; Kong, X; ... ECLIPSE, ICGN, and COPDGene Investigators,; + view all (2012) Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. Am J Respir Crit Care Med , 186 (12) 1238 - 1247. 10.1164/rccm.201206-1013OC.

Klionsky, DJ; Abdalla, FC; Abeliovich, H; Abraham, RT; Acevedo-Arozena, A; Adeli, K; ... Zuckerbraun, B; + view all (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy , 8 (4) 445 - 544.

Knight, A; Arnouk, H; Gillespie, G; Britt, W; Su, Y; Lowdell, MW; Lamb, LS; (2012) CYTOMEGALOVIRUS-INDEPENDENT LYSIS OF GLIOMA-DERIVED CELL LINES AND PRIMARY TUMOR EXPLANTS BY IN VITRO EXPANDED/ACTIVATED V Delta 1+Gamma Delta T CELLS. In: NEURO-ONCOLOGY. (pp. 38 - 38).

Knight, A; Mackinnon, S; Lowdell, MW; (2012) Human Vdelta1 gamma-delta T cells exert potent specific cytotoxicity against primary multiple myeloma cells. Cytotherapy , 14 (9) 1110 - 1118. 10.3109/14653249.2012.700766.

Kumita, JR; Helmfors, L; Williams, J; Luheshi, LM; Menzer, L; Dumoulin, M; ... Brorsson, AC; + view all (2012) Disease-related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster. FASEB J , 26 (1) 192 - 202. 10.1096/fj.11-185983.

L

Lanceley, A; Eagle, Z; Ogden, G; Gessler, S; Razvi, K; Ledermann, JA; Side, L; (2012) Family history and women with ovarian cancer: is it asked and does it matter?: An observational study. Int J Gynecol Cancer , 22 (2) 254 - 259. 10.1097/IGC.0b013e3182392714.

Ledermann, J; Harter, P; Gourley, C; Friedlander, M; Vergote, I; Rustin, G; ... Matulonis, U; + view all (2012) Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer. N Engl J Med , 366 (15) 1382 - 1392. 10.1056/NEJMoa1105535.

Lee, SM; Khan, I; Upadhyay, S; Lewanski, C; Falk, S; Skailes, G; ... Boshoff, C; + view all (2012) First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial. Lancet Oncol , 13 (11) 1161 - 1170. 10.1016/S1470-2045(12)70412-6. Gold open access

Li, M; Wu, H; Luo, Z; Xia, Y; Guan, J; Wang, T; ... Li, R; + view all (2012) An atlas of DNA methylomes in porcine adipose and muscle tissues. Nat Commun , 3 850 - ?. 10.1038/ncomms1854.

Lomas, DA; Lipson, DA; Miller, BE; Willits, L; Keene, O; Barnacle, H; ... Losmapimod Study Investigators,; + view all (2012) An oral inhibitor of p38 MAP kinase reduces plasma fibrinogen in patients with chronic obstructive pulmonary disease. J Clin Pharmacol , 52 (3) 416 - 424. 10.1177/0091270010397050.

Lowdell, MW; (2012) Natural Killer T cells - balancing the regulation of tumor immunity. Br J Cancer , 107 (10) 1795 - 1796. 10.1038/bjc.2012.453.

Lowdell, MW; Birchall, M; Thrasher, AJ; (2012) Use of compassionate-case ATMP in preclinical data for clinical trial applications. Lancet , 379 (9834) 2341 - ?. 10.1016/S0140-6736(12)61018-6.

Lowdell, MW; Samuel, E; (2012) Processing of Cells for Transplantation. In: UNSPECIFIED (271 - 292).

M

Majumder, B; North, J; Mavroudis, C; Lowdell, MW; Rakhit, R; (2012) Improved accuracy and reproducibility of enumeration of platelet-monocyte complexes through use of doublet-discriminator strategy. Cytometry Part B - Clinical Cytometry , 82 B (6) 353 - 359. 10.1002/cyto.b.21040.

Majumder, B; North, J; Mavroudis, C; Rakhit, R; Lowdell, MW; (2012) Improved accuracy and reproducibility of enumeration of platelet-monocyte complexes through use of doublet-discriminator strategy. Cytometry B Clin Cytom , 82 (6) 353 - 359. 10.1002/cyto.b.21040.

Majumder, B; North, J; Mavroudis, C; Rakhit, R; Lowdell, MW; (2012) Toward new insights on the white blood cell differential by flow cytometry: A proof of concept study on the sepsis model. CYTOMETRY PART B-CLINICAL CYTOMETRY , 82B (6) 353 - 359. 10.1002/cyto.b.21027.

McNeill, A; Duran, R; Proukakis, C; Bras, J; Hughes, D; Mehta, A; ... Schapira, AH; + view all (2012) Hyposmia and cognitive impairment in Gaucher disease patients and carriers. Mov Disord , 27 (4) 526 - 532. 10.1002/mds.24945.

Mendoza-Naranjo, A; Cormie, P; Serrano, AE; Hu, R; O'Neill, S; Wang, CM; ... Becker, DL; + view all (2012) Targeting Cx43 and N-cadherin, which are abnormally upregulated in venous leg ulcers, influences migration, adhesion and activation of Rho GTPases. PLOS One , 7 (5) , Article e37374. 10.1371/journal.pone.0037374. Green and gold open access
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Michod, D; Bartesaghi, S; Khelifi, A; Bellodi, C; Berliocchi, L; Nicotera, P; Salomoni, P; (2012) Calcium-dependent dephosphorylation of the histone chaperone DAXX regulates H3.3 loading and transcription upon neuronal activation. Neuron , 74 (1) 122 - 135. 10.1016/j.neuron.2012.02.021. Green and gold open access
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N

Nürnberg, ST; Rendon, A; Smethurst, PA; Paul, DS; Voss, K; Thon, JN; ... Ouwehand, WH; + view all (2012) A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site. Blood , 120 (24) 4859 - 4868. 10.1182/blood-2012-01-401893.

Nyon, MP; Segu, L; Cabrita, LD; Lévy, GR; Kirkpatrick, J; Roussel, BD; ... Gooptu, B; + view all (2012) Structural dynamics associated with intermediate formation in an archetypal conformational disease. Structure , 20 (3) 504 - 512. 10.1016/j.str.2012.01.012.

O

Oseni, A; Crowley, C; Seifalian, AM; Lowdell, M; Birchall, M; Butler, PE; (2012) Advancing nasal reconstructive surgery: The application of tissue engineering technology. Journal of Tissue Engineering and Regenerative Medicine , 6 (10) 757 - 768. 10.1002/term.487.

P

Payne, EM; Virgilio, M; Narla, A; Sun, H; Levine, M; Paw, BH; ... Khanna-Gupta, A; + view all (2012) L-Leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway. Blood , 120 (11) 2214 - 2224. 10.1182/blood-2011-10-382986.

Q

Qiu, W; Baccarelli, A; Carey, VJ; Boutaoui, N; Bacherman, H; Klanderman, B; ... DeMeo, DL; + view all (2012) Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function. Am J Respir Crit Care Med , 185 (4) 373 - 381. 10.1164/rccm.201108-1382OC.

R

Raja, FA; Hook, JM; Ledermann, JA; (2012) Biomarkers in the development of anti-angiogenic therapies for ovarian cancer. Cancer Treat Rev , 38 (6) 662 - 672. 10.1016/j.ctrv.2011.11.009.

Ramage, JK; Ahmed, A; Ardill, J; Bax, N; Breen, DJ; Caplin, ME; ... Grossman, AB; + view all (2012) Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs). GUT , 61 (1) 6 - 32. 10.1136/gutjnl-2011-300831.

Ramasubramanyan, S; Kanhere, A; Osborn, K; Flower, K; Jenner, RG; Sinclair, AJ; (2012) Genome-wide analyses of Zta binding to the Epstein-Barr virus genome reveals interactions in both early and late lytic cycles and an epigenetic switch leading to an altered binding profile. J Virol , 86 (23) 12494 - 12502. 10.1128/JVI.01705-12.

Rashid, ST; Lomas, DA; (2012) Stem cell-based therapy for α₁-antitrypsin deficiency. Stem Cell Res Ther , 3 (1) 4 - ?. 10.1186/scrt95.

Ruers, T; Punt, C; Van Coevorden, F; Pierie, JP; Borel-Rinkes, I; Ledermann, JA; ... EORTC Gastro-Intestinal Tract Cancer Group, Arbeitsgruppe Lebermetastasen und—tumoren in der Chirurgischen Arbeitsgemeinschaft Onkologie (ALM-CAO) and the National Cancer Research Institute Colorectal Clinical Study Group (NCRI CCSG),; + view all (2012) Radiofrequency ablation combined with systemic treatment versus systemic treatment alone in patients with non-resectable colorectal liver metastases: a randomized EORTC Intergroup phase II study (EORTC 40004). Ann Oncol , 23 (10) 2619 - 2626. 10.1093/annonc/mds053.

S

Sabry, M; Lowdell, MW; (2012) Natural Killer Cell Responses to Tumor Priming. In: EUROPEAN JOURNAL OF CANCER. (pp. S86 - S86).

Schmid, ST; Koepke, J; Dresel, M; Hattesohl, A; Frenzel, E; Perez, J; ... Koczulla, AR; + view all (2012) The effects of weekly augmentation therapy in patients with PiZZ α1-antitrypsin deficiency. Int J Chron Obstruct Pulmon Dis , 7 687 - 696. 10.2147/COPD.S34560.

Sellar, RS; Peggs, KS; (2012) Therapeutic strategies for the prevention and treatment of cytomegalovirus infection. Expert Opin Biol Ther , 12 (9) 1161 - 1172. 10.1517/14712598.2012.693471.

Shepherd, C; Banerjee, L; Cheung, CW; Mansour, MR; Jenkinson, S; Gale, RE; Khwaja, A; (2012) PI3K/mTOR Inhibition Upregulates NOTCH-MYC Signalling Leading to an Impaired Cytotoxic Response. In: BLOOD.

Sive, JI; Buck, G; Fielding, A; Lazarus, HM; Litzow, MR; Luger, S; ... Goldstone, AH; + view all (2012) Outcomes in older adults with acute lymphoblastic leukaemia (ALL): results from the international MRC UKALL XII/ECOG2993 trial. Br J Haematol , 157 (4) 463 - 471. 10.1111/j.1365-2141.2012.09095.x.

Slater, S; Witteveen, PO; Plummer, R; Kristeleit, R; Evans, TRJ; Reyderman, L; ... Schellens, JHM; + view all (2012) 599 Effect of Food On Relative Bioavailability of E7820 in Cancer Patients. European Journal of Cancer , 48 , Article S6. 10.1016/S0959-8049(12)72396-1.

Speretta, E; Jahn, TR; Tartaglia, GG; Favrin, G; Barros, TP; Imarisio, S; ... Dobson, CM; + view all (2012) Expression in drosophila of tandem amyloid β peptides provides insights into links between aggregation and neurotoxicity. J Biol Chem , 287 (24) 20748 - 20754. 10.1074/jbc.M112.350124.

Spruit, MA; Polkey, MI; Celli, B; Edwards, LD; Watkins, ML; Pinto-Plata, V; ... Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) study investigators,; + view all (2012) Predicting outcomes from 6-minute walk distance in chronic obstructive pulmonary disease. J Am Med Dir Assoc , 13 (3) 291 - 297. 10.1016/j.jamda.2011.06.009.

Stolk, J; Stockley, RA; Stoel, BC; Cooper, BG; Piitulainen, E; Seersholm, N; ... Rames, A; + view all (2012) Randomised controlled trial for emphysema with a selective agonist of the γ-type retinoic acid receptor. Eur Respir J , 40 (2) 306 - 312. 10.1183/09031936.00161911.

T

Taiwo, O; Wilson, GA; Morris, T; Seisenberger, S; Reik, W; Pearce, D; ... Butcher, LM; + view all (2012) Methylome analysis using MeDIP-seq with low DNA concentrations. Nat Protoc , 7 (4) 617 - 636. 10.1038/nprot.2012.012.

U

Ubhi, BK; Cheng, KK; Dong, J; Janowitz, T; Jodrell, D; Tal-Singer, R; ... Connor, SC; + view all (2012) Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD. Mol Biosyst , 8 (12) 3125 - 3133. 10.1039/c2mb25194a.

Ubhi, BK; Riley, JH; Shaw, PA; Lomas, DA; Tal-Singer, R; MacNee, W; ... Connor, SC; + view all (2012) Metabolic profiling detects biomarkers of protein degradation in COPD patients. Eur Respir J , 40 (2) 345 - 355. 10.1183/09031936.00112411.

V

van der Harst, P; Zhang, W; Mateo Leach, I; Rendon, A; Verweij, N; Sehmi, J; ... Chambers, JC; + view all (2012) Seventy-five genetic loci influencing the human red blood cell. Nature , 492 (7429) 369 - 375. 10.1038/nature11677.

W

Wan, ES; Qiu, W; Baccarelli, A; Carey, VJ; Bacherman, H; Rennard, SI; ... DeMeo, DL; + view all (2012) Systemic steroid exposure is associated with differential methylation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med , 186 (12) 1248 - 1255. 10.1164/rccm.201207-1280OC.

Wan, ES; Qiu, W; Baccarelli, A; Carey, VJ; Bacherman, H; Rennard, SI; ... Demeo, DL; + view all (2012) Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome. Hum Mol Genet , 21 (13) 3073 - 3082. 10.1093/hmg/dds135.

Wilk, JB; Shrine, NR; Loehr, LR; Zhao, JH; Manichaikul, A; Lopez, LM; ... Stricker, BH; + view all (2012) Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Am J Respir Crit Care Med , 186 (7) 622 - 632. 10.1164/rccm.201202-0366OC.

Windsor, RE; Strauss, SJ; Kallis, C; Wood, NE; Whelan, JS; (2012) Germline Genetic Polymorphisms May Influence Chemotherapy Response and Disease Outcome in Osteosarcoma. CANCER , 118 (7) 1856 - 1867. 10.1002/cncr.26472.

Y

Young, RJ; Tin, AW; Brown, NJ; Jitlal, M; Lee, SM; Woll, PJ; (2012) Analysis of circulating angiogenic biomarkers from patients in two phase III trials in lung cancer of chemotherapy alone or chemotherapy and thalidomide. Br J Cancer , 106 (6) 1153 - 1159. 10.1038/bjc.2012.50.

Z

Zhuang, J; Widschwendter, M; Teschendorff, AE; (2012) A comparison of feature selection and classification methods in DNA methylation studies using the Illumina Infinium platform. BMC Bioinformatics , 13 59 - ?. 10.1186/1471-2105-13-59. Gold open access

This list was generated on Sun Oct 26 02:30:58 2014 GMT.