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Jump to: A | B | C | D | J | K | L | N | Q | R | S | T | U | W
Number of items: 25.

A

Agustí, A and Edwards, LD and Rennard, SI and MacNee, W and Tal-Singer, R and Miller, BE and Vestbo, J and Lomas, DA and Calverley, PM and Wouters, E and Crim, C and Yates, JC and Silverman, EK and Coxson, HO and Bakke, P and Mayer, RJ and Celli, B and Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators, (2012) Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype. PLoS One , 7 (5) , Article e37483. 10.1371/journal.pone.0037483.
An open access publication. A version is also available from UCL Discovery.
 file

Albert, P and Agusti, A and Edwards, L and Tal-Singer, R and Yates, J and Bakke, P and Celli, BR and Coxson, HO and Crim, C and Lomas, DA and Macnee, W and Miller, B and Rennard, S and Silverman, EK and Vestbo, J and Wouters, E and Calverley, P (2012) Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease. Thorax , 67 (8) 701 - 708. 10.1136/thoraxjnl-2011-201458.

Aminuddin, F and Akhabir, L and Stefanowicz, D and Paré, PD and Connett, JE and Anthonisen, NR and Fahy, JV and Seibold, MA and Burchard, EG and Eng, C and Gulsvik, A and Bakke, P and Cho, MH and Litonjua, A and Lomas, DA and Anderson, WH and Beaty, TH and Crapo, JD and Silverman, EK and Sandford, AJ (2012) Genetic association between human chitinases and lung function in COPD. Hum Genet , 131 (7) 1105 - 1114. 10.1007/s00439-011-1127-1.

B

Bafadhel, M and McKenna, S and Terry, S and Mistry, V and Pancholi, M and Venge, P and Lomas, DA and Barer, MR and Johnston, SL and Pavord, ID and Brightling, CE (2012) Blood eosinophils to direct corticosteroid treatment of exacerbations of chronic obstructive pulmonary disease: a randomized placebo-controlled trial. Am J Respir Crit Care Med , 186 (1) 48 - 55. 10.1164/rccm.201108-1553OC.

C

Celli, BR and Locantore, N and Yates, J and Tal-Singer, R and Miller, BE and Bakke, P and Calverley, P and Coxson, H and Crim, C and Edwards, LD and Lomas, DA and Duvoix, A and MacNee, W and Rennard, S and Silverman, E and Vestbo, J and Wouters, E and Agustí, A and ECLIPSE Investigators, (2012) Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease. Am J Respir Crit Care Med , 185 (10) 1065 - 1072. 10.1164/rccm.201110-1792OC.

Cho, MH and Castaldi, PJ and Wan, ES and Siedlinski, M and Hersh, CP and Demeo, DL and Himes, BE and Sylvia, JS and Klanderman, BJ and Ziniti, JP and Lange, C and Litonjua, AA and Sparrow, D and Regan, EA and Make, BJ and Hokanson, JE and Murray, T and Hetmanski, JB and Pillai, SG and Kong, X and Anderson, WH and Tal-Singer, R and Lomas, DA and Coxson, HO and Edwards, LD and MacNee, W and Vestbo, J and Yates, JC and Agusti, A and Calverley, PM and Celli, B and Crim, C and Rennard, S and Wouters, E and Bakke, P and Gulsvik, A and Crapo, JD and Beaty, TH and Silverman, EK and ICGN Investigators, and ECLIPSE Investigators, and COPDGene Investigators, (2012) A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Hum Mol Genet , 21 (4) 947 - 957. 10.1093/hmg/ddr524.

D

Dickens, JA and Lomas, DA (2012) CC-16 as a biomarker in chronic obstructive pulmonary disease. COPD , 9 (5) 574 - 575. 10.3109/15412555.2012.718926.

Duvoix, A and Dickens, J and Haq, I and Mannino, D and Miller, B and Tal-Singer, R and Lomas, DA (2012) Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease. Thorax 10.1136/thoraxjnl-2012-201871.

J

Jagroop-Dearing, I.A. (2012) Effect of antithrombotic drugs on platelet function and receptors and an investigation into platelet cholesterol. Doctoral thesis, UCL (University College London).
An open access version is available from UCL Discovery
 file

K

Kim, DK and Cho, MH and Hersh, CP and Lomas, DA and Miller, BE and Kong, X and Bakke, P and Gulsvik, A and Agustí, A and Wouters, E and Celli, B and Coxson, H and Vestbo, J and MacNee, W and Yates, JC and Rennard, S and Litonjua, A and Qiu, W and Beaty, TH and Crapo, JD and Riley, JH and Tal-Singer, R and Silverman, EK and ECLIPSE, ICGN, and COPDGene Investigators, (2012) Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. Am J Respir Crit Care Med , 186 (12) 1238 - 1247. 10.1164/rccm.201206-1013OC.

Kumita, JR and Helmfors, L and Williams, J and Luheshi, LM and Menzer, L and Dumoulin, M and Lomas, DA and Crowther, DC and Dobson, CM and Brorsson, AC (2012) Disease-related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster. FASEB J , 26 (1) 192 - 202. 10.1096/fj.11-185983.

L

Lomas, DA and Lipson, DA and Miller, BE and Willits, L and Keene, O and Barnacle, H and Barnes, NC and Tal-Singer, R and Losmapimod Study Investigators, (2012) An oral inhibitor of p38 MAP kinase reduces plasma fibrinogen in patients with chronic obstructive pulmonary disease. J Clin Pharmacol , 52 (3) 416 - 424. 10.1177/0091270010397050.

N

Nyon, MP and Segu, L and Cabrita, LD and Lévy, GR and Kirkpatrick, J and Roussel, BD and Patschull, AO and Barrett, TE and Ekeowa, UI and Kerr, R and Waudby, CA and Kalsheker, N and Hill, M and Thalassinos, K and Lomas, DA and Christodoulou, J and Gooptu, B (2012) Structural dynamics associated with intermediate formation in an archetypal conformational disease. Structure , 20 (3) 504 - 512. 10.1016/j.str.2012.01.012.

Q

Qiu, W and Baccarelli, A and Carey, VJ and Boutaoui, N and Bacherman, H and Klanderman, B and Rennard, S and Agusti, A and Anderson, W and Lomas, DA and DeMeo, DL (2012) Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function. Am J Respir Crit Care Med , 185 (4) 373 - 381. 10.1164/rccm.201108-1382OC.

R

Rashid, ST and Lomas, DA (2012) Stem cell-based therapy for α₁-antitrypsin deficiency. Stem Cell Res Ther , 3 (1) 4 - ?. 10.1186/scrt95.

S

Schmid, ST and Koepke, J and Dresel, M and Hattesohl, A and Frenzel, E and Perez, J and Lomas, DA and Miranda, E and Greulich, T and Noeske, S and Wencker, M and Teschler, H and Vogelmeier, C and Janciauskiene, S and Koczulla, AR (2012) The effects of weekly augmentation therapy in patients with PiZZ α1-antitrypsin deficiency. Int J Chron Obstruct Pulmon Dis , 7 687 - 696. 10.2147/COPD.S34560.

Speretta, E and Jahn, TR and Tartaglia, GG and Favrin, G and Barros, TP and Imarisio, S and Lomas, DA and Luheshi, LM and Crowther, DC and Dobson, CM (2012) Expression in drosophila of tandem amyloid β peptides provides insights into links between aggregation and neurotoxicity. J Biol Chem , 287 (24) 20748 - 20754. 10.1074/jbc.M112.350124.

Spruit, MA and Polkey, MI and Celli, B and Edwards, LD and Watkins, ML and Pinto-Plata, V and Vestbo, J and Calverley, PM and Tal-Singer, R and Agusti, A and Coxson, HO and Lomas, DA and MacNee, W and Rennard, S and Silverman, EK and Crim, CC and Yates, J and Wouters, EF and Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) study investigators, (2012) Predicting outcomes from 6-minute walk distance in chronic obstructive pulmonary disease. J Am Med Dir Assoc , 13 (3) 291 - 297. 10.1016/j.jamda.2011.06.009.

Stolk, J and Stockley, RA and Stoel, BC and Cooper, BG and Piitulainen, E and Seersholm, N and Chapman, KR and Burdon, JG and Decramer, M and Abboud, RT and Mannes, GP and Wouters, EF and Garrett, JE and Barros-Tizon, JC and Russi, EW and Lomas, DA and MacNee, WA and Rames, A (2012) Randomised controlled trial for emphysema with a selective agonist of the γ-type retinoic acid receptor. Eur Respir J , 40 (2) 306 - 312. 10.1183/09031936.00161911.

T

Taylor, C (2012) Gender, work and psychological distress in hospital consultants. Doctoral thesis, UCL (University College London).

U

Ubhi, BK and Cheng, KK and Dong, J and Janowitz, T and Jodrell, D and Tal-Singer, R and MacNee, W and Lomas, DA and Riley, JH and Griffin, JL and Connor, SC (2012) Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD. Mol Biosyst , 8 (12) 3125 - 3133. 10.1039/c2mb25194a.

Ubhi, BK and Riley, JH and Shaw, PA and Lomas, DA and Tal-Singer, R and MacNee, W and Griffin, JL and Connor, SC (2012) Metabolic profiling detects biomarkers of protein degradation in COPD patients. Eur Respir J , 40 (2) 345 - 355. 10.1183/09031936.00112411.

W

Wan, ES and Qiu, W and Baccarelli, A and Carey, VJ and Bacherman, H and Rennard, SI and Agustí, A and Anderson, WH and Lomas, DA and DeMeo, DL (2012) Systemic steroid exposure is associated with differential methylation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med , 186 (12) 1248 - 1255. 10.1164/rccm.201207-1280OC.

Wan, ES and Qiu, W and Baccarelli, A and Carey, VJ and Bacherman, H and Rennard, SI and Agusti, A and Anderson, W and Lomas, DA and Demeo, DL (2012) Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome. Hum Mol Genet , 21 (13) 3073 - 3082. 10.1093/hmg/dds135.

Wilk, JB and Shrine, NR and Loehr, LR and Zhao, JH and Manichaikul, A and Lopez, LM and Smith, AV and Heckbert, SR and Smolonska, J and Tang, W and Loth, DW and Curjuric, I and Hui, J and Cho, MH and Latourelle, JC and Henry, AP and Aldrich, M and Bakke, P and Beaty, TH and Bentley, AR and Borecki, IB and Brusselle, GG and Burkart, KM and Chen, TH and Couper, D and Crapo, JD and Davies, G and Dupuis, J and Franceschini, N and Gulsvik, A and Hancock, DB and Harris, TB and Hofman, A and Imboden, M and James, AL and Khaw, KT and Lahousse, L and Launer, LJ and Litonjua, A and Liu, Y and Lohman, KK and Lomas, DA and Lumley, T and Marciante, KD and McArdle, WL and Meibohm, B and Morrison, AC and Musk, AW and Myers, RH and North, KE and Postma, DS and Psaty, BM and Rich, SS and Rivadeneira, F and Rochat, T and Rotter, JI and Artigas, MS and Starr, JM and Uitterlinden, AG and Wareham, NJ and Wijmenga, C and Zanen, P and Province, MA and Silverman, EK and Deary, IJ and Palmer, LJ and Cassano, PA and Gudnason, V and Barr, RG and Loos, RJ and Strachan, DP and London, SJ and Boezen, HM and Probst-Hensch, N and Gharib, SA and Hall, IP and O'Connor, GT and Tobin, MD and Stricker, BH (2012) Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Am J Respir Crit Care Med , 186 (7) 622 - 632. 10.1164/rccm.201202-0366OC.

This list was generated on Sun May 19 06:54:56 2013 BST.