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Abdallah, QM; Phillips, RM; Johansson, F; Helleday, T; Cosentino, L; Abdel-Rahman, H; ... Pors, K; + view all (2012) Minor structural modifications to alchemix influence mechanism of action and pharmacological activity. Biochem Pharmacol , 83 (11) 1514 - 1522. 10.1016/j.bcp.2012.02.017.

Adair, JR; Howard, PW; Hartley, JA; Williams, DG; Chester, KA; (2012) Antibody-drug conjugates - a perfect synergy. Expert Opin Biol Ther , 12 (9) 1191 - 1206. 10.1517/14712598.2012.693473.

Adams, D; Altucci, L; Antonarakis, SE; Ballesteros, J; Beck, S; Bird, A; ... Willcocks, S; + view all (2012) BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol , 30 (3) 224 - 226. 10.1038/nbt.2153.

Agostinelli, C; Paterson, JC; Gupta, R; Righi, S; Sandri, F; Piccaluga, PP; ... Marafioti, T; + view all (2012) Detection of LIM domain only 2 (LMO2) in normal human tissues and haematopoietic and non-haematopoietic tumours using a newly developed rabbit monoclonal antibody. Histopathology , 61 (1) 33 - 46. 10.1111/j.1365-2559.2012.04198.x.

Agustí, A; Edwards, LD; Rennard, SI; MacNee, W; Tal-Singer, R; Miller, BE; ... Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators,; + view all (2012) Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype. PLoS One , 7 (5) , Article e37483. 10.1371/journal.pone.0037483. Green open access

Aksoy, E; Taboubi, S; Torres, D; Delbauve, S; Hachani, A; Whitehead, MA; ... Vanhaesebroeck, B; + view all (2012) The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock. Nat Immunol , 13 (11) 1045 - 1054. 10.1038/ni.2426.

Al-Thihli, K; Ebrahim, H; Hughes, DA; Patel, M; Tipple, M; Salvarinova, R; ... Waters, PJ; + view all (2012) A variant of unknown significance in the GLA gene causing diagnostic uncertainty in a young female with isolated hypertrophic cardiomyopathy. Gene , 497 (2) 320 - 322. 10.1016/j.gene.2012.01.056.

Albers, CA; Paul, DS; Schulze, H; Freson, K; Stephens, JC; Smethurst, PA; ... Ghevaert, C; + view all (2012) Compound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome. Nat Genet , 44 (4) 435 - S2. 10.1038/ng.1083.

Albert, P; Agusti, A; Edwards, L; Tal-Singer, R; Yates, J; Bakke, P; ... Calverley, P; + view all (2012) Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease. Thorax , 67 (8) 701 - 708. 10.1136/thoraxjnl-2011-201458.

Alcolea, MP; Casado, P; Rodríguez-Prados, JC; Vanhaesebroeck, B; Cutillas, PR; (2012) Phosphoproteomic analysis of leukemia cells under basal and drug-treated conditions identifies markers of kinase pathway activation and mechanisms of resistance. Mol Cell Proteomics , 11 (8) 453 - 466. 10.1074/mcp.M112.017483.

Ali, S; Sergeant, R; Foroni, L; Gerrard, G; Milojkovic, D; Stringaris, K; ... Clark, RE; + view all (2012) Dasatinib may overcome the negative prognostic impact of KIR2DS1 in newly diagnosed patients with chronic myeloid leukemia. Blood , 120 (3) 697 - 698. 10.1182/blood-2012-04-421016.

Alikian, M; Gerrard, G; Subramanian, PG; Mudge, K; Foskett, P; Khorashad, JS; ... Foroni, L; + view all (2012) BCR-ABL1 kinase domain mutations: methodology and clinical evaluation. Am J Hematol , 87 (3) 298 - 304. 10.1002/ajh.22272.

Alvarez-Secord, A; Barnett, J; Ledermann, J; Peterson, B; Myers, E; Havrilesky, L; (2012) Cost-effectiveness of homologous recombination defect testing to target PARP inhibitor use in platinum-sensitive recurrent ovarian cancer. GYNECOLOGIC ONCOLOGY , 125 S92 - S93. 10.1016/j.ygyno.2011.12.223.

Amé-Thomas, P; Le Priol, J; Yssel, H; Caron, G; Pangault, C; Jean, R; ... Tarte, K; + view all (2012) Characterization of intratumoral follicular helper T cells in follicular lymphoma: role in the survival of malignant B cells. Leukemia , 26 (5) 1053 - 1063. 10.1038/leu.2011.301.

Aminuddin, F; Akhabir, L; Stefanowicz, D; Paré, PD; Connett, JE; Anthonisen, NR; ... Sandford, AJ; + view all (2012) Genetic association between human chitinases and lung function in COPD. Hum Genet , 131 (7) 1105 - 1114. 10.1007/s00439-011-1127-1.

Anthoney, DA; Naik, J; MacPherson, IRJ; Crawford, D; Hartley, JM; Hartley, JA; ... Evans, TRJ; + view all (2012) Phase I study of TP300 in patients with advanced solid tumors with pharmacokinetic, pharmacogenetic and pharmacodynamic analyses. BMC Cancer , 12 , Article 536. 10.1186/1471-2407-12-536. Green open access

Arkenau, H-T; Saggese, M; Lemech, C; (2012) Advanced gastric cancer: Is there enough evidence to call second-line therapy standard? World Journal of Gastroenterology , 18 (44) 6376 - 6378. 10.3748/wjg.v18.i44.6376. Gold open access

Arkenau, H-T; Saggese, M; Lemech, C; (2012) Dabrafenib mesylate: Serine/threonine-protein kinase B-raf inhibitor oncolytic. Drugs of the Future , 37 (7) 469 - 474. 10.1358/dof.2012.37.7.1820872.

Arkenau, HT; Plummer, R; Molife, LR; Olmos, D; Yap, TA; Squires, M; ... Judson, I; + view all (2012) A phase I dose escalation study of AT9283, a small molecule inhibitor of aurora kinases, in patients with advanced solid malignancies. Ann Oncol , 23 (5) 1307 - 1313. 10.1093/annonc/mdr451.

Armstrong, CA; Jones, GD; Anderson, R; Iyer, P; Narayanan, D; Sandhu, J; ... Tufarelli, C; + view all (2012) DNMTs are required for delayed genome instability caused by radiation. Epigenetics , 7 (8) 892 - 902. 10.4161/epi.21094.

Asghar, U; Meyer, T; (2012) Are there opportunities for chemotherapy in the treatment of hepatocellular cancer? J Hepatol , 56 (3) 686 - 695. 10.1016/j.jhep.2011.07.031.

Aslan, D; Akata, RF; Holme, H; Vulliamy, T; Dokal, I; (2012) Limbal stem cell deficiency in patients with inherited stem cell disorder of dyskeratosis congenita. Int Ophthalmol , 32 (6) 615 - 622. 10.1007/s10792-012-9611-8.

Aydinok, Y; Evans, P; Manz, CY; Porter, JB; (2012) Timed non-transferrin bound iron determinations probe the origin of chelatable iron pools during deferiprone regimens and predict chelation response. Haematologica , 97 (6) 835 - 841. 10.3324/haematol.2011.056317.

Bachner, M; Loriot, Y; Gross-Goupil, M; Zucali, PA; Horwich, A; Germa-Lluch, JR; ... De Santis, M; + view all (2012) 2-¹⁸fluoro-deoxy-D-glucose positron emission tomography (FDG-PET) for postchemotherapy seminoma residual lesions: a retrospective validation of the SEMPET trial. Ann Oncol , 23 (1) 59 - 64. 10.1093/annonc/mdr052.

Bafadhel, M; McKenna, S; Terry, S; Mistry, V; Pancholi, M; Venge, P; ... Brightling, CE; + view all (2012) Blood eosinophils to direct corticosteroid treatment of exacerbations of chronic obstructive pulmonary disease: a randomized placebo-controlled trial. Am J Respir Crit Care Med , 186 (1) 48 - 55. 10.1164/rccm.201108-1553OC.

Ballabio, E; Armesto, M; Breeze, CE; Manterola, L; Arestin, M; Tramonti, D; ... Lawrie, CH; + view all (2012) Bortezomib action in multiple myeloma: microRNA-mediated synergy (and miR-27a/CDK5 driven sensitivity)? Blood Cancer Journal , 2 (8) e83 - e83. 10.1038/bcj.2012.31.

Bates, AW; (2012) Diagnosing eosinophilic colitis: histopathological pattern or nosological entity? Scientifica , 2012 , Article 682576. 10.6064/2012/682576. Green open access

Baud, MG; Leiser, T; Haus, P; Samlal, S; Wong, AC; Wood, RJ; ... Fuchter, MJ; + view all (2012) Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets. J Med Chem , 55 (4) 1731 - 1750. 10.1021/jm2016182.

Beck, S; Bernstein, BE; Campbell, RM; Costello, JF; Dhanak, D; Ecker, JR; ... AACR Cancer Epigenome Task Force,; + view all (2012) A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force. Cancer Res , 72 (24) 6319 - 6324. 10.1158/0008-5472.CAN-12-3658.

Beggs, AD; Domingo, E; McGregor, M; Presz, M; Johnstone, E; Midgley, R; ... Tomlinson, IP; + view all (2012) Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN. Oncotarget , 3 (11) 1348 - 1355.

Bell, CG; Wilson, GA; Butcher, LM; Roos, C; Walter, L; Beck, S; (2012) Human-specific CpG "beacons" identify loci associated with human-specific traits and disease. Epigenetics , 7 (10) 1188 - 1199. 10.4161/epi.22127. Green open access


Bennett, CL; Chakraverty, R; (2012) Dendritic cells in tissues: in situ stimulation of immunity and immunopathology. Trends Immunol , 33 (1) 8 - 13. 10.1016/j.it.2011.09.008.

Berenjeno, IM; Guillermet-Guibert, J; Pearce, W; Gray, A; Fleming, S; Vanhaesebroeck, B; (2012) Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor. Biochem J , 442 (1) 151 - 159. 10.1042/BJ20111741.

Biegstraaten, M; Wesnes, KA; Luzy, C; Petakov, M; Mrsic, M; Niederau, C; ... van Schaik, IN; + view all (2012) The cognitive profile of type 1 Gaucher disease patients. J Inherit Metab Dis , 35 (6) 1093 - 1099. 10.1007/s10545-012-9460-7.

Birkbak, NJ; Wang, ZC; Kim, JY; Eklund, AC; Li, Q; Tian, R; ... Richardson, AL; + view all (2012) Telomeric allelic imbalance indicates defective DNA repair and sensitivity to DNA-damaging agents. Cancer Discov , 2 (4) 366 - 375. 10.1158/2159-8290.CD-11-0206.

Brown, JH; Tellez, J; Wilson, V; Mackie, IJ; Scully, M; Tredger, MM; ... Goodship, TH; + view all (2012) Postpartum aHUS secondary to a genetic abnormality in factor H acquired through liver transplantation. Am J Transplant , 12 (6) 1632 - 1636. 10.1111/j.1600-6143.2012.03991.x.

Cain, RJ; Vanhaesebroeck, B; Ridley, AJ; (2012) Different PI 3-kinase inhibitors have distinct effects on endothelial permeability and leukocyte transmigration. Int J Biochem Cell Biol , 44 (11) 1929 - 1936. 10.1016/j.biocel.2012.07.009.

Calabretta, B; Salomoni, P; (2012) Suppression of autophagy by BCR/ABL. Front Biosci (Schol Ed) , 4 453 - 460.

Calleja-Agius, J; Jauniaux, E; Pizzey, AR; Muttukrishna, S; (2012) Investigation of systemic inflammatory response in first trimester pregnancy failure. Hum Reprod , 27 (2) 349 - 357. 10.1093/humrep/der402.

Camilleri, RS; Scully, M; Thomas, M; Mackie, IJ; Liesner, R; Chen, WJ; ... Machin, SJ; + view all (2012) A phenotype-genotype correlation of ADAMTS13 mutations in congenital thrombotic thrombocytopenic purpura patients treated in the United Kingdom. J Thromb Haemost , 10 (9) 1792 - 1801. 10.1111/j.1538-7836.2012.04852.x.

Camilleri, RS; Thomas, M; Mackie, IJ; Chen, WJ; Manns, K; Machin, SJ; ... Liesner, R; + view all (2012) A phenotype-genotype correlation of ADAMTS13 mutations in congenital thrombotic thrombocytopenic purpura patients treated in the United Kingdom. Journal of Thrombosis and Haemostasis , 10 (9) 1792 - 1801. 10.1111/j.1538-7836.2012.04852.x.

Campbell, EC; Antoniou, AN; Powis, SJ; (2012) The multi-faceted nature of HLA class I dimer molecules. Immunology , 136 (4) 380 - 384. 10.1111/j.1365-2567.2012.03593.x.

Campbell, NH; Karim, NH; Parkinson, GN; Gunaratnam, M; Petrucci, V; Todd, AK; ... Neidle, S; + view all (2012) Molecular basis of structure-activity relationships between salphen metal complexes and human telomeric DNA quadruplexes. J Med Chem , 55 (1) 209 - 222. 10.1021/jm201140v.

Canzonetta, C; Hoischen, A; Giarin, E; Basso, G; Veltman, JA; Nacheva, E; ... Groet, J; + view all (2012) Amplified segment in the 'Down syndrome critical region' on HSA21 shared between Down syndrome and euploid AML-M0 excludes RUNX1, ERG and ETS2. Br J Haematol , 157 (2) 197 - 200. 10.1111/j.1365-2141.2011.08985.x.

Carmichael, CL; Metcalf, D; Henley, KJ; Kruse, EA; Di Rago, L; Mifsud, S; ... Kile, BT; + view all (2012) Hematopoietic overexpression of the transcription factor Erg induces lymphoid and erythro-megakaryocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America , 109 (38) 15437 - 15442. 10.1073/pnas.1213454109.

Celli, BR; Locantore, N; Yates, J; Tal-Singer, R; Miller, BE; Bakke, P; ... ECLIPSE Investigators,; + view all (2012) Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease. Am J Respir Crit Care Med , 185 (10) 1065 - 1072. 10.1164/rccm.201110-1792OC.

Chakraverty, R; (2012) Do educated natural killer cells make the grade in treating acute myeloid leukemia? Haematologica , 97 (11) 1617 - ?. 10.3324/haematol.2012.078717.

Chan, W-C; Ho, M-R; Li, S-C; Tsai, K-W; Lai, C-H; Hsu, C-N; Lin, W-C; (2012) MetaMirClust: Discovery of miRNA cluster patterns using a data-mining approach. Genomics , 100 (3) 141 - 148. 10.1016/j.ygeno.2012.06.007.

Charalambous, BM; (2012) Identifying divergent streptococcal strains using pherotype: implications for pathogen emergence and epidemiology. Future Microbiol , 7 (12) 1349 - 1354. 10.2217/fmb.12.114.

Charalambous, BM; Leung, MH; (2012) Pneumococcal sepsis and nasopharyngeal carriage. Curr Opin Pulm Med , 18 (3) 222 - 227. 10.1097/MCP.0b013e328352103b.

Chatterjee, R; Shah, FT; Davis, BA; Byers, M; Sooranna, D; Bajoria, R; ... Porter, JB; + view all (2012) Prospective study of histomorphometry, biochemical bone markers and bone densitometric response to pamidronate in beta-thalassaemia presenting with osteopenia-osteoporosis syndrome. BRITISH JOURNAL OF HAEMATOLOGY , 159 (4) 462 - 471. 10.1111/bjh.12048.

Chen, C; Constantinou, A; Chester, KA; Vyas, B; Canis, K; Haslam, SM; ... Deonarain, MP; + view all (2012) Glycoengineering approach to half-life extension of recombinant biotherapeutics. Bioconjug Chem , 23 (8) 1524 - 1533. 10.1021/bc200624a.

Chen, P; Tu, X; Akdemir, F; Chew, SK; Rothenfluh, A; Abrams, JM; (2012) Effectors of alcohol-induced cell killing in Drosophila. Cell Death Differ , 19 (10) 1655 - 1663. 10.1038/cdd.2012.47.

Chiesa, R; Gilmour, K; Qasim, W; Adams, S; Worth, AJJ; Zhan, H; ... Veys, P; + view all (2012) Omission of in vivo T-cell depletion promotes rapid expansion of naive CD4(+) cord blood lymphocytes and restores adaptive immunity within 2 months after unrelated cord blood transplant. BRITISH JOURNAL OF HAEMATOLOGY , 156 (5) 656 - 666. 10.1111/j.1365-2141.2011.08994.x.

Cho, MH; Castaldi, PJ; Wan, ES; Siedlinski, M; Hersh, CP; Demeo, DL; ... COPDGene Investigators,; + view all (2012) A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Hum Mol Genet , 21 (4) 947 - 957. 10.1093/hmg/ddr524.

Cox, ST; Madrigal, JA; Saudemont, A; (2012) Three novel allelic variants of the RAET1E/ULBP4 gene in humans. Tissue Antigens , 80 (4) 390 - 392. 10.1111/j.1399-0039.2012.01933.x.

Danovi, D; Folarin, AA; Baranowski, B; Pollard, SM; (2012) High content screening of defined chemical libraries using normal and glioma-derived neural stem cell lines. Methods Enzymol , 506 311 - 329. 10.1016/B978-0-12-391856-7.00040-8.

de Groot, NG; Otting, N; Robinson, J; Blancher, A; Lafont, BA; Marsh, SG; ... Bontrop, RE; + view all (2012) Nomenclature report on the major histocompatibility complex genes and alleles of Great Ape, Old and New World monkey species. Immunogenetics , 64 615 - 631. 10.1007/s00251-012-0617-1.


Della Peruta, M; Binny, C; Nathwani, D; McIntosh, J; Rosales, C; Davidoff, AM; ... Nathwani, AC; + view all (2012) DEVELOPMENT OF A LIVER-SPECIFIC, TUMOUR-SELECTIVE RECOMBINANT ADENO-ASSOCIATED VIRUS VECTOR TO TARGET HEPATOCELLULAR CARCINOMA. GUT , 61 A201 - A201. 10.1136/gutjnl-2012-302514c.43.

Dessimoz, C; Gabaldón, T; Roos, DS; Sonnhammer, EL; Herrero, J; Quest for Orthologs Consortium,; (2012) Toward community standards in the quest for orthologs. Bioinformatics , 28 (6) 900 - 904. 10.1093/bioinformatics/bts050.

Dickens, JA; Lomas, DA; (2012) CC-16 as a biomarker in chronic obstructive pulmonary disease. COPD , 9 (5) 574 - 575. 10.3109/15412555.2012.718926.

Dignan, FL; Amrolia, P; Clark, A; Cornish, J; Jackson, G; Mahendra, P; ... British Society for Blood and Marrow Transplantation,; + view all (2012) Diagnosis and management of chronic graft-versus-host disease. Br J Haematol , 158 (1) 46 - 61. 10.1111/j.1365-2141.2012.09128.x.

Dignan, FL; Clark, A; Amrolia, P; Cornish, J; Jackson, G; Mahendra, P; ... British Society for Blood and Marrow Transplantation,; + view all (2012) Diagnosis and management of acute graft-versus-host disease. Br J Haematol , 158 (1) 30 - 45. 10.1111/j.1365-2141.2012.09129.x.

Dignan, FL; Greenblatt, D; Cox, M; Cavenagh, J; Oakervee, H; Apperley, JF; ... Scarisbrick, JJ; + view all (2012) Efficacy of bimonthly extracorporeal photopheresis in refractory chronic mucocutaneous GVHD. Bone Marrow Transplant , 47 (6) 824 - 830. 10.1038/bmt.2011.186.

Dignan, FL; Greenblatt, D; Scarisbrick, JJ; Potter, MN; Shaw, BE; Cox, M; ... Medd, P; + view all (2012) Efficacy of bimonthly extracorporeal photopheresis in refractory chronic mucocutaneous GVHD. Bone Marrow Transplantation , 47 (6) 824 - 830. 10.1038/bmt.2011.186.

Dobricic, V; Stefanova, E; Jankovic, M; Gurunlian, N; Novakovic, I; Hardy, J; ... Guerreiro, R; + view all (2012) Genetic testing in familial and young-onset Alzheimer's disease: mutation spectrum in a Serbian cohort. Neurobiol Aging , 33 (7) 1481.e7 - 1481.12. 10.1016/j.neurobiolaging.2011.12.007.

Dubois, E; Jacoby, M; Blockmans, M; Pernot, E; Schiffmann, SN; Foukas, LC; ... Schurmans, S; + view all (2012) Developmental defects and rescue from glucose intolerance of a catalytically-inactive novel Ship2 mutant mouse. Cell Signal , 24 (11) 1971 - 1980. 10.1016/j.cellsig.2012.06.012.

Duhamel, LA; Ye, H; Halai, D; Idowu, BD; Presneau, N; Tirabosco, R; Flanagan, AM; (2012) Frequency of Mouse Double Minute 2 (MDM2) and Mouse Double Minute 4 (MDM4) amplification in parosteal and conventional osteosarcoma subtypes. Histopathology , 60 (2) 357 - 359. 10.1111/j.1365-2559.2011.04023.x.

Dunlop, MG; Dobbins, SE; Farrington, SM; Jones, AM; Palles, C; Whiffin, N; ... Houlston, RS; + view all (2012) Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Nat Genet , 44 (7) 770 - 776. 10.1038/ng.2293.

Duran, R; McNeill, A; Mehta, A; Hughes, D; Cox, T; Deegan, P; ... Hardy, J; + view all (2012) Novel pathogenic mutations in the glucocerebrosidase locus. Mol Genet Metab , 106 (4) 495 - 497. 10.1016/j.ymgme.2012.05.006. Gold open access

Ebrahim, HY; Baker, RJ; Mehta, AB; Hughes, DA; (2012) Functional analysis of variant lysosomal acid glycosidases of Anderson-Fabry and Pompe disease in a human embryonic kidney epithelial cell line (HEK 293 T). J Inherit Metab Dis , 35 (2) 325 - 334. 10.1007/s10545-011-9395-4.

El-Andaloussi, S; Lee, Y; Lakhal-Littleton, S; Li, J; Seow, Y; Gardiner, C; ... Wood, MJ; + view all (2012) Exosome-mediated delivery of siRNA in vitro and in vivo. Nat Protoc , 7 (12) 2112 - 2126. 10.1038/nprot.2012.131.

ENCODE Project Consortium,; (2012) An integrated encyclopedia of DNA elements in the human genome. Nature , 489 (7414) 57 - 74. 10.1038/nature11247.

Engström, PG; Tommei, D; Stricker, SH; Ender, C; Pollard, SM; Bertone, P; (2012) Digital transcriptome profiling of normal and glioblastoma-derived neural stem cells identifies genes associated with patient survival. Genome Med , 4 (10) 76 - ?. 10.1186/gm377.


Erturan, G; Holme, H; Cassoni, A; Tirabosco, R; Pollock, R; Briggs, T; Michelagnoli, M; (2012) The importance of patient reported functional outcome in paediatric desmoid fibromatosis. Rare Tumors , 4 (3) e38 - ?. 10.4081/rt.2012.e38.

Erturan, G; Holme, H; Iyer, S; (2012) Corynebacterium pseudodiphtheriticum septic arthritis secondary to intra-articular injection--a case report and literature review. J Med Microbiol , 61 (Pt 6) 860 - 863. 10.1099/jmm.0.037937-0.

Erturan, G; Holme, H; Smith, R; Dodds, R; Iyer, S; (2012) Successful use of daptomycin in Panton-Valentine leucocidin positive Staphylococcus aureus paediatric osteomyelitis. Int J Surg Case Rep , 3 (7) 238 - 241. 10.1016/j.ijscr.2012.03.014.

Fagone, P; Nienhuis, AW; Gray, JT; Fraser Wright, J; Nathwani, AC; Davidoff, AM; (2012) Systemic errors in quantitative polymerase chain reaction titration of self-complementary adeno-associated viral vectors and improved alternative methods. Human Gene Therapy Methods , 23 (1) 1 - 7. 10.1089/hgtb.2011.104.

Falchook, GS; Kurzrock, R; Kim, KB; Long, GV; Kefford, RF; Arkenau, TH; ... Ouellet, D; + view all (2012) Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: A phase 1 dose-escalation trial. The Lancet , 379 (9829) 1893 - 1901. 10.1016/S0140-6736(12)60398-5.

Falk, A; Koch, P; Kesavan, J; Takashima, Y; Ladewig, J; Alexander, M; ... Brüstle, O; + view all (2012) Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons. PLOS One , 7 (1) , Article e29597. 10.1371/journal.pone.0029597. Green open access

Feng, H; Hu, B; Jarzynka, MJ; Li, Y; Keezer, S; Johns, TG; ... Cheng, SY; + view all (2012) Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis. Proc Natl Acad Sci U S A , 109 (8) 3018 - 3023. 10.1073/pnas.1121457109.

Fenton, TR; Nathanson, D; Ponte de Albuquerque, C; Kuga, D; Iwanami, A; Dang, J; ... Furnari, FB; + view all (2012) Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240. Proc Natl Acad Sci U S A , 109 (35) 14164 - 14169. 10.1073/pnas.1211962109.

Fernandez, AF; Assenov, Y; Martin-Subero, JI; Balint, B; Siebert, R; Taniguchi, H; ... Esteller, M; + view all (2012) A DNA methylation fingerprint of 1628 human samples. Genome Res , 22 (2) 407 - 419. 10.1101/gr.119867.110.

Fielding, AK; Banerjee, L; Marks, DI; (2012) Recent developments in the management of T-cell precursor acute lymphoblastic leukemia/lymphoma. Curr Hematol Malig Rep , 7 (2) 160 - 169. 10.1007/s11899-012-0123-4.

Fielding, AK; Lee, L; (2012) Emerging pharmacotherapies for adult patients with acute lymphoblastic leukemia. Clinical Medicine Insights: Oncology , 6 85 - 100. 10.4137/CMO.S7262. Gold open access

Fizazi, K; Scher, HI; Molina, A; Logothetis, CJ; Chi, KN; Jones, RJ; ... COU-AA-301 Investigators,; + view all (2012) Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study. Lancet Oncol , 13 (10) 983 - 992. 10.1016/S1470-2045(12)70379-0.

Flaherty, K; Metric Study Group,; (2012) Improved survival with MEK inhibition in BRAF-mutated melanoma. New England Journal of Medicine 10.1056/NEJMoa1203421.

Fleischhauer, K; Shaw, BE; Gooley, T; Malkki, M; Bardy, P; Bignon, JD; ... International Histocompatibility Working Group in Hematopoietic Cell Transplantation,; + view all (2012) Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: a retrospective study. Lancet Oncol , 13 (4) 366 - 374. 10.1016/S1470-2045(12)70004-9.

Fleischhauer, K; Shaw, BE; Madrigal, JA; Gooley, T; Malkki, M; Bardy, P; ... Velardi, A; + view all (2012) Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: A retrospective study. The Lancet Oncology , 13 (4) 366 - 374. 10.1016/S1470-2045(12)70004-9.

Flicek, P; Amode, MR; Barrell, D; Beal, K; Brent, S; Carvalho-Silva, D; ... Searle, SM; + view all (2012) Ensembl 2012. Nucleic Acids Res , 40 (Database issue) D84 - D90. 10.1093/nar/gkr991.

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Book chapter

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Häusser, M; Spruston, N; Stuart, G; (2012) Conclusion. In: UNSPECIFIED

Lianos, I; Odudu, O; (2012) Introduction. In: UNSPECIFIED (1 - 14).

Lowdell, MW; Samuel, E; (2012) Processing of Cells for Transplantation. In: UNSPECIFIED (271 - 292).

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Conference item



Bates, AW; (2012) Morbid Curiosities: Medical Museums in Nineteenth-Century Britain. UNSPECIFIED

Proceedings paper

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Conlan, T; Sivakumaran, J; Fallah-Arani, F; Zhang, L; Means, T; Geissman, F; ... Bennett, C; + view all (2012) Investigating the role of cutaneous dendritic cells in T-cell mediated immunopathology. In: IMMUNOLOGY. (pp. 479 - 479).

Davidoff, A; Tuddenham, EGD; Rangarajan, S; Rosales, C; McIntosh, J; Chowdary, P; ... Nathwani, AC; + view all (2012) Stable Factor IX Activity Following AAV-Mediated Gene Transfer in Patients with Severe Hemophilia B. In: BLOOD.


Dey, A; Zhang, Y; Castleton, A; Patel, B; Ghorani, E; Rai, L; ... Fielding, A; + view all (2012) Polymorphonuclear Neutrophils(PMNs) Are Cytotoxic for Measles Virus (MV)-Infected Tumor Cells Ex-Vivo, but Their Role in MV-Mediated Oncolysis In-Vivo Is Tumor-Type Dependent. In: MOLECULAR THERAPY. (pp. S271 - S271).

Fields, P; Townsend, WM; Webb, A; Pocock, CFE; Smith, P; Kirkwood, A; ... Cunningham, D; + view all (2012) First analysis of a phase II multicentre trial of rituximab, gemcitabine, cyclophosphamide, vincristine and prednisolone (R-GCVP) for patients with newly diagnosed diffuse large B cell lymphoma (DLBCL) considered unsuitable for anthracycline containing chemo-immunotherapy. An NCRI lymphoma clinical studies group trial. CRUK/07/007. In: BRITISH JOURNAL OF HAEMATOLOGY. (pp. 13 - 14).

Fishman, J; Ansari, T; Sibbons, P; Lowdell, M; De Coppi, P; Birchall, M; (2012) Characterisation and immunogenicity of a decellularised skeletal muscle scaffold for laryngeal tissue engineering. In: JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE. (pp. 174 - 174).

Glynne-Jones, R; James, R; Meadows, H; Begum, R; Cunningham, D; Northover, J; ... Grp, ACTIIS; + view all (2012) Optimum time to assess complete clinical response (CR) following chemoradiation (CRT) using mitomycin (MMC) or cisplatin (CisP), with or without maintenance CisP/5FU in squamous cell carcinoma of the anus: Results of ACT II. In: JOURNAL OF CLINICAL ONCOLOGY.

Glynne-Jones, R; James, R; Meadows, H; Begum, R; Cunningham, D; Northover, J; ... Grp, ACTIIS; + view all (2012) Optimum time to assess complete clinical response (CR) following chemoradiation (CRT) using mitomycin (MMC) or cisplatin (CisP), with or without maintenance CisP/5FU in squamous cell carcinoma of the anus: Results of ACT II. In: JOURNAL OF CLINICAL ONCOLOGY.

Griffin, J; Carpenter, B; Nicholson, E; Ghorasian, S; Holler, A; Velica, P; ... Chakraverty, R; + view all (2012) Gaining an advantage: mycophenolate-resistance for adoptively transferred cells. In: IMMUNOLOGY. (pp. 742 - 742).

Helgason, GV; Allan, E; Galavotti, S; Audia, A; Hamilton, A; Mukhopadhyay, A; ... Holyoake, TL; + view all (2012) Ponatinib and inhibition of the PI3K/Akt/mTOR pathway induces cell death and protective autophagy in TKI-resistant CML stem/progenitor cells. In: BRITISH JOURNAL OF HAEMATOLOGY. (pp. 1 - 1).

Helgason, GV; Allan, EK; Mariani, S; Mukhopadhyay, A; Karvela, M; Galavotti, S; ... Holyoake, TL; + view all (2012) Inhibition of Autophagy in Combination with Ponatinib or Dual PI3K/mTOR Inhibition to Improve Treatment Response for Both Bcr-Abl Dependent and Independent Mechanisms of TKI-Resistance in CML. In: BLOOD.

Howard-Reeves, J; Brazma, D; Partheniou, P; Gancheva, K; Kotzampaltiris, P; Grace, C; Nacheva, E; (2012) The Common Deleted Region in the Short ARM of Chromosome 17 in CLL Includes the MAP2K4 GENE. In: BLOOD.

Jeyapalan, JN; Patel, SN; Forshew, T; Lawson, ARJ; Tatevossian, RG; Corbett-Jones, T; ... Sheer, D; + view all (2012) MICRORNA SIGNATURES IN A BROAD COHORT OF PAEDIATRIC BRAIN TUMOURS. In: PEDIATRIC BLOOD & CANCER. (pp. 1084 - 1084).

Johnson, SP; Laufer, JG; Zhang, EZ; Beard, PC; Pedley, RB; (2012) Determination of Differential Tumour Vascular Pathophysiology in Vivo by Photoacoustic Imaging. In: EUROPEAN JOURNAL OF CANCER. (pp. S186 - S187).

Khan, MS; Tsigani, T; Garcia-Hernandez, J; Hartley, JA; Caplin, ME; Meyer, T; (2012) Circulating tumor cells as prognostic and predictive markers in neuroendocrine tumors. In: JOURNAL OF CLINICAL ONCOLOGY.


Kotzampaltiris, P; Zareian, N; Brazma, D; Gancheva, K; Howard-Reeves, J; Grace, C; Nacheva, E; (2012) FISH screening for TET2 deletions. In: JOURNAL OF MEDICAL GENETICS. (pp. S44 - S44).

Lambertsen, KL; Anthony, DC; Couch, Y; Martin, NA; Ormhoj, M; Schmidt, M-LB; ... others,; + view all (2012) Anti-TNF therapy improves behavioural outcomes after focal cerebral ischemia in mice. In: JOURNAL OF NEUROIMMUNOLOGY. (pp. 101 - 101).


Lee, M; Satam, V; Babu, B; Gregory, M; Bowerman, M; Savagian, M; ... Hartley, JA; + view all (2012) Complete analysis on the two base pair sequence recognition by Hx (p-anisylbenzimidazole)center dot pyrrole and Hx center dot imidazole pairings. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.

Lee, M; Satam, V; Babu, B; Porte, A; Savagian, M; Lee, MD; ... Hartley, JA; + view all (2012) Synthesis and DNA binding properties of 1-(3-aminopropyl)imidazole-containing triamide f-Im*PyIm: a novel diamino polyamide designed to target 5 '-ACGCGT-3 '. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.

Maharaj, L; Popat, R; Gribben, JG; Joel, S; (2012) IL-6, IL-8 and VEGF Neutralisation Restores Drug Sensitivity to Conventional and Novel Treatment Combinations in a Multiple Myeloma Bone Marrow Micro-Environment Model. In: BLOOD.

Manousou, P; Tsianou, Z; Burroughs, AK; Dhillon, AP; Hall, AR; Tzallas, AT; ... Tsianos, EV; + view all (2012) Digital image analysis of collagen for chronic Hepatitis B patients. Should we follow the treatment guidelines? In: HEPATOLOGY. (pp. 411A - 412A).

Mattar, CN; Nathwani, A; Rosales, C; Waddington, S; Johana, N; Ng, X-W; ... Chan, JKY; + view all (2012) Early AAV-Mediated Intrauterine Gene Therapy at 0.4G in Non-Human Primates. In: MOLECULAR THERAPY. (pp. S252 - S253).

McNeill, A; Hughes, D; Mehta, A; Schapira, A; (2012) Hyposmia and cognitive impairment in gaucher disease patients and carriers. In: JOURNAL OF MEDICAL GENETICS. (pp. S63 - S63).

Meyer, T; Caplin, M; Reed, N; Qian, W; Lao-Sirieix, S; Armstrong, G; ... Corrie, P; + view all (2012) TREATMENT OF ADVANCED NEUROENDOCRINE TUMOURS: FINAL RESULTS OF THE UKINETS AND NCRI RANDOMISED PHASE 2 NET01 TRIAL. In: ANNALS OF ONCOLOGY. (pp. 378 - 379).

Morris, CR; Kim, H-Y; Wood, JC; Trachtenberg, F; Klings, ES; Porter, JB; ... Kuypers, FA; + view all (2012) Cardiopulmonary and Laboratory Profiling of Patients with Thalassemia At Risk for Pulmonary Hypertension: Report From the Thalassemia Clinical Research Network. In: BLOOD.

Morris, CR; Kim, H-Y; Wood, JC; Trachtenberg, F; Klings, ES; Porter, JB; ... Vichinsky, E; + view all (2012) Sildenafil Therapy in Patients with Thalassemia and an Elevated Tricuspid Regurgitant Jet Velocity (TRV) On Doppler Echocardiography At Risk for Pulmonary Hypertension: Report From the Thalassemia Clinical Research Network. In: BLOOD.



Pennell, DJ; Porter, JB; Piga, A; Lai, Y; El-Beshlawy, A; Beloul, K; ... Aydinok, Y; + view all (2012) A Multicenter, Randomized, Open-Label Trial Evaluating Deferasirox Compared with Deferoxamine for the Removal of Cardiac Iron in Patients with beta-Thalassemia Major and Iron Overload (CORDELIA). In: BLOOD.

Pericleous, M; Lumgair, H; Reiner, J; Marelli, L; Caplin, M; Meyer, T; Toumpanakis, C; (2012) Bronchial neuroendocrine tumors: A retrospective review of management and outcomes in 116 patients. In: JOURNAL OF CLINICAL ONCOLOGY.

Philip, B; Flutter, B; Chakraverty, R; Jathoul, A; Pule, M; (2012) A Highly Compact Epitope-Based Marker Suicide Gene for Safer and Easier Adoptive T-Cell Gene Therapy. In: MOLECULAR THERAPY. (pp. S35 - S36).

Porter, JB; Elalfy, M; Viprakasit, V; Giraudier, S; Chan, LL; Lai, Y; ... Cappellini, MD; + view all (2012) Serum Ferritin, Labile Plasma Iron and Transferrin Saturation: Comparison Between Underlying Anemias with Transfusional Iron Overload Before and After Treatment with Deferasirox. In: BLOOD.

Porter, JB; Walter, PB; Neumayr, LD; Evans, P; Weyhmiller, MG; Harmatz, P; ... Vichinsky, E; + view all (2012) Iron Trafficking and Distribution in Transfusional Overload: Insights From Comparing Diamond Blackfan Anemia with Sickle Cell Disease and Thalassemia. In: BLOOD.


Redman, C; Tannetta, D; Southcombe, J; Dragovic, B; Gardiner, C; Collett, G; Sargent, I; (2012) THE DANGEROUS PLACENTA AND PRE-ECLAMPSIA, A REVIEW. In: PLACENTA. (pp. A12 - A12).

Sabry, M; Lowdell, MW; (2012) Natural Killer Cell Responses to Tumor Priming. In: EUROPEAN JOURNAL OF CANCER. (pp. S86 - S86).

Sebag-Montefiore, D; James, R; Meadows, H; Begum, R; Cunningham, D; Northover, J; ... Grp, ACTIIS; + view all (2012) The pattern and timing of disease recurrence in squamous cancer of the anus: Mature results from the NCRI ACT II trial. In: JOURNAL OF CLINICAL ONCOLOGY.

Starke, RD; Paschalaki, KE; Ferraro, F; Dryden, NH; McKinnon, TAJ; Sutton, RE; ... Randi, AM; + view all (2012) Endothelial Von Willebrand factor regulates angiogenesis. In: VASCULAR PHARMACOLOGY. (pp. 318 - 319).

Thirlwell, C; Sasmaz, S; Dibra, H; Feber, A; Butcher, L; Meyer, T; ... Beck, S; + view all (2012) The First Neuroendocrine Tumor Methylome Using Methylation-Specific Immunoprecipitation Followed by Second Generation Sequencing - MeDIP-seq. In: NEUROENDOCRINOLOGY. (pp. 14 - 14).

Toumpanakis, C; Baneke, A; Pericleous, M; Meyer, T; Caplin, ME; (2012) Diagnostic and therapeutic outcomes in goblet cell appendiceal neuroendocrine tumors. In: JOURNAL OF CLINICAL ONCOLOGY.

Townsend, WM; Johnson, RJ; Counsell, N; Shah, H; Pottinger, B; Evans, K; ... Claudius, R; + view all (2012) A Phase II Clinical Trial of Fludarabine and Cyclophosphamide Followed by Thalidomide for Angioimmunoblastic Lymphoma (AITL), an NCRI Clinical Trial. CRUK C17050/A5671. In: BLOOD.

Vincenzi, B; Santini, D; Schiavon, G; Frezza, AM; Dileo, P; Silletta, M; ... Tonini, G; + view all (2012) Bone metastases in soft tissue sarcoma patients: A survey of natural, prognostic value, and treatment. In: JOURNAL OF CLINICAL ONCOLOGY.

Walter, PB; Harmatz, P; Higa, A; Ng, V; Weyhmiller, MG; Evans, P; ... Vichinsky, E; + view all (2012) Innate Immune Cell Expression of Pattern Recognition Receptors From beta-Thalassemia Patients During Intensive Combination Chelation Therapy. In: BLOOD.


Ye, H; Berisha, F; Alorjani, M; Eskandarpour, M; Diss, T; Tirabosco, R; ... Amary, M; + view all (2012) Detection of USP6 Gene Rearrangement in Nodular Fasciitis. An Important Diagnostic Tool. In: JOURNAL OF MOLECULAR DIAGNOSTICS. (pp. 705 - 705).


Jagroop-Dearing, I.A.; (2012) Effect of antithrombotic drugs on platelet function and receptors and an investigation into platelet cholesterol. Doctoral thesis, UCL (University College London). Green open access

This list was generated on Sun Jun 28 03:55:41 2015 BST.