UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Browse by UCL Departments and Centres

Up a level
Export as [feed] RSS 2.0 [feed] RSS 1.0 [feed] Atom
Group by: Author | Type
Number of items: 73.

Article

Adams, D; Altucci, L; Antonarakis, SE; Ballesteros, J; Beck, S; Bird, A; ... Willcocks, S; + view all (2012) BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol , 30 (3) 224 - 226. 10.1038/nbt.2153.

Agbamu, DA; Day, N; Walsh, CJ; Hendrickse, CW; Langman, G; Pallan, A; ... Lees, N; + view all (2012) Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: The pilot phase of a randomised controlled trial. The Lancet Oncology , 13 (11) 1152 - 1160. 10.1016/S1470-2045(12)70348-0. Green and gold open access
file

Agustí, A; Edwards, LD; Rennard, SI; MacNee, W; Tal-Singer, R; Miller, BE; ... Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators,; + view all (2012) Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype. PLoS One , 7 (5) , Article e37483. 10.1371/journal.pone.0037483. Green and gold open access
file

Albert, P; Agusti, A; Edwards, L; Tal-Singer, R; Yates, J; Bakke, P; ... Calverley, P; + view all (2012) Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease. Thorax , 67 (8) 701 - 708. 10.1136/thoraxjnl-2011-201458.

Aminuddin, F; Akhabir, L; Stefanowicz, D; Paré, PD; Connett, JE; Anthonisen, NR; ... Sandford, AJ; + view all (2012) Genetic association between human chitinases and lung function in COPD. Hum Genet , 131 (7) 1105 - 1114. 10.1007/s00439-011-1127-1.

Bafadhel, M; McKenna, S; Terry, S; Mistry, V; Pancholi, M; Venge, P; ... Brightling, CE; + view all (2012) Blood eosinophils to direct corticosteroid treatment of exacerbations of chronic obstructive pulmonary disease: a randomized placebo-controlled trial. Am J Respir Crit Care Med , 186 (1) 48 - 55. 10.1164/rccm.201108-1553OC.

Celli, BR; Locantore, N; Yates, J; Tal-Singer, R; Miller, BE; Bakke, P; ... ECLIPSE Investigators,; + view all (2012) Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease. Am J Respir Crit Care Med , 185 (10) 1065 - 1072. 10.1164/rccm.201110-1792OC.

Cho, MH; Castaldi, PJ; Wan, ES; Siedlinski, M; Hersh, CP; Demeo, DL; ... COPDGene Investigators,; + view all (2012) A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Hum Mol Genet , 21 (4) 947 - 957. 10.1093/hmg/ddr524.

Dickens, JA; Lomas, DA; (2012) CC-16 as a biomarker in chronic obstructive pulmonary disease. COPD , 9 (5) 574 - 575. 10.3109/15412555.2012.718926.

Dobricic, V; Stefanova, E; Jankovic, M; Gurunlian, N; Novakovic, I; Hardy, J; ... Guerreiro, R; + view all (2012) Genetic testing in familial and young-onset Alzheimer's disease: mutation spectrum in a Serbian cohort. Neurobiol Aging , 33 (7) 1481.e7 - 1481.12. 10.1016/j.neurobiolaging.2011.12.007.

Dunlop, MG; Dobbins, SE; Farrington, SM; Jones, AM; Palles, C; Whiffin, N; ... Houlston, RS; + view all (2012) Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Nat Genet , 44 (7) 770 - 776. 10.1038/ng.2293.

ENCODE Project Consortium,; (2012) An integrated encyclopedia of DNA elements in the human genome. Nature , 489 (7414) 57 - 74. 10.1038/nature11247.

Falchook, GS; Kurzrock, R; Kim, KB; Long, GV; Kefford, RF; Arkenau, TH; ... Ouellet, D; + view all (2012) Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: A phase 1 dose-escalation trial. The Lancet , 379 (9829) 1893 - 1901. 10.1016/S0140-6736(12)60398-5.

Fenton, TR; Nathanson, D; Ponte de Albuquerque, C; Kuga, D; Iwanami, A; Dang, J; ... Furnari, FB; + view all (2012) Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240. Proc Natl Acad Sci U S A , 109 (35) 14164 - 14169. 10.1073/pnas.1211962109.

Fernandez, AF; Assenov, Y; Martin-Subero, JI; Balint, B; Siebert, R; Taniguchi, H; ... Esteller, M; + view all (2012) A DNA methylation fingerprint of 1628 human samples. Genome Res , 22 (2) 407 - 419. 10.1101/gr.119867.110.

Fizazi, K; Scher, HI; Molina, A; Logothetis, CJ; Chi, KN; Jones, RJ; ... COU-AA-301 Investigators,; + view all (2012) Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study. Lancet Oncol , 13 (10) 983 - 992. 10.1016/S1470-2045(12)70379-0.

Fleischhauer, K; Shaw, BE; Madrigal, JA; Gooley, T; Malkki, M; Bardy, P; ... Velardi, A; + view all (2012) Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: A retrospective study. The Lancet Oncology , 13 (4) 366 - 374. 10.1016/S1470-2045(12)70004-9.

Gerlinger, M; Rowan, AJ; Horswell, S; Larkin, J; Endesfelder, D; Gronroos, E; ... Swanton, C; + view all (2012) Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med , 366 (10) 883 - 892. 10.1056/NEJMoa1113205.

Gisselbrecht, C; Schmitz, N; Mounier, N; Singh Gill, D; Linch, DC; Trneny, M; ... Glass, B; + view all (2012) Rituximab maintenance therapy after autologous stem-cell transplantation in patients with relapsed CD20(+) diffuse large B-cell lymphoma: final analysis of the collaborative trial in relapsed aggressive lymphoma. J Clin Oncol , 30 (36) 4462 - 4469. 10.1200/JCO.2012.41.9416.

Guerreiro, RJ; Lohmann, E; Kinsella, E; Brás, JM; Luu, N; Gurunlian, N; ... Singleton, A; + view all (2012) Exome sequencing reveals an unexpected genetic cause of disease: NOTCH3 mutation in a Turkish family with Alzheimer's disease. Neurobiol Aging , 33 (5) 1008.e17 - 1008.e23. 10.1016/j.neurobiolaging.2011.10.009.

Jitlal, M; Khan, I; Lee, SM; Hackshaw, A; (2012) Stopping clinical trials early for futility: retrospective analysis of several randomised clinical studies. British Journal of Cancer , 107 (6) 910 - 917. 10.1038/bjc.2012.344. Green and gold open access
file

Keeling, D; Mackie, I; Moore, GW; Greer, IA; Greaves, M; Haematology, BCS; (2012) Guidelines on the investigation and management of antiphospholipid syndrome. BRITISH JOURNAL OF HAEMATOLOGY , 157 (1) 47 - 58. 10.1111/j.1365-2141.2012.09037.x.

Kim, DK; Cho, MH; Hersh, CP; Lomas, DA; Miller, BE; Kong, X; ... ECLIPSE, ICGN, and COPDGene Investigators,; + view all (2012) Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. Am J Respir Crit Care Med , 186 (12) 1238 - 1247. 10.1164/rccm.201206-1013OC.

Klionsky, DJ; Abdalla, FC; Abeliovich, H; Abraham, RT; Acevedo-Arozena, A; Adeli, K; ... Zuckerbraun, B; + view all (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy , 8 (4) 445 - 544.

Knight, A; Mackinnon, S; Lowdell, MW; (2012) Human Vdelta1 gamma-delta T cells exert potent specific cytotoxicity against primary multiple myeloma cells. Cytotherapy , 14 (9) 1110 - 1118. 10.3109/14653249.2012.700766.

Kumita, JR; Helmfors, L; Williams, J; Luheshi, LM; Menzer, L; Dumoulin, M; ... Brorsson, AC; + view all (2012) Disease-related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster. FASEB J , 26 (1) 192 - 202. 10.1096/fj.11-185983.

Lanceley, A; Eagle, Z; Ogden, G; Gessler, S; Razvi, K; Ledermann, JA; Side, L; (2012) Family history and women with ovarian cancer: is it asked and does it matter?: An observational study. Int J Gynecol Cancer , 22 (2) 254 - 259. 10.1097/IGC.0b013e3182392714.

Ledermann, J; Harter, P; Gourley, C; Friedlander, M; Vergote, I; Rustin, G; ... Matulonis, U; + view all (2012) Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer. N Engl J Med , 366 (15) 1382 - 1392. 10.1056/NEJMoa1105535.

Lee, SM; Khan, I; Upadhyay, S; Lewanski, C; Falk, S; Skailes, G; ... Boshoff, C; + view all (2012) First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial. Lancet Oncol , 13 (11) 1161 - 1170. 10.1016/S1470-2045(12)70412-6. Gold open access

Li, M; Wu, H; Luo, Z; Xia, Y; Guan, J; Wang, T; ... Li, R; + view all (2012) An atlas of DNA methylomes in porcine adipose and muscle tissues. Nat Commun , 3 850 - ?. 10.1038/ncomms1854.

Lomas, DA; Lipson, DA; Miller, BE; Willits, L; Keene, O; Barnacle, H; ... Losmapimod Study Investigators,; + view all (2012) An oral inhibitor of p38 MAP kinase reduces plasma fibrinogen in patients with chronic obstructive pulmonary disease. J Clin Pharmacol , 52 (3) 416 - 424. 10.1177/0091270010397050.

Lowdell, MW; (2012) Natural Killer T cells - balancing the regulation of tumor immunity. Br J Cancer , 107 (10) 1795 - 1796. 10.1038/bjc.2012.453.

Lowdell, MW; Birchall, M; Thrasher, AJ; (2012) Use of compassionate-case ATMP in preclinical data for clinical trial applications. Lancet , 379 (9834) 2341 - ?. 10.1016/S0140-6736(12)61018-6.

Majumder, B; North, J; Mavroudis, C; Lowdell, MW; Rakhit, R; (2012) Improved accuracy and reproducibility of enumeration of platelet-monocyte complexes through use of doublet-discriminator strategy. Cytometry Part B - Clinical Cytometry , 82 B (6) 353 - 359. 10.1002/cyto.b.21040.

Majumder, B; North, J; Mavroudis, C; Rakhit, R; Lowdell, MW; (2012) Improved accuracy and reproducibility of enumeration of platelet-monocyte complexes through use of doublet-discriminator strategy. Cytometry B Clin Cytom , 82 (6) 353 - 359. 10.1002/cyto.b.21040.

Majumder, B; North, J; Mavroudis, C; Rakhit, R; Lowdell, MW; (2012) Toward new insights on the white blood cell differential by flow cytometry: A proof of concept study on the sepsis model. CYTOMETRY PART B-CLINICAL CYTOMETRY , 82B (6) 353 - 359. 10.1002/cyto.b.21027.

McNeill, A; Duran, R; Proukakis, C; Bras, J; Hughes, D; Mehta, A; ... Schapira, AH; + view all (2012) Hyposmia and cognitive impairment in Gaucher disease patients and carriers. Mov Disord , 27 (4) 526 - 532. 10.1002/mds.24945.

Mendoza-Naranjo, A; Cormie, P; Serrano, AE; Hu, R; O'Neill, S; Wang, CM; ... Becker, DL; + view all (2012) Targeting Cx43 and N-cadherin, which are abnormally upregulated in venous leg ulcers, influences migration, adhesion and activation of Rho GTPases. PLOS One , 7 (5) , Article e37374. 10.1371/journal.pone.0037374. Green and gold open access
file

Michod, D; Bartesaghi, S; Khelifi, A; Bellodi, C; Berliocchi, L; Nicotera, P; Salomoni, P; (2012) Calcium-dependent dephosphorylation of the histone chaperone DAXX regulates H3.3 loading and transcription upon neuronal activation. Neuron , 74 (1) 122 - 135. 10.1016/j.neuron.2012.02.021. Green and gold open access
file

Nürnberg, ST; Rendon, A; Smethurst, PA; Paul, DS; Voss, K; Thon, JN; ... Ouwehand, WH; + view all (2012) A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site. Blood , 120 (24) 4859 - 4868. 10.1182/blood-2012-01-401893.

Nyon, MP; Segu, L; Cabrita, LD; Lévy, GR; Kirkpatrick, J; Roussel, BD; ... Gooptu, B; + view all (2012) Structural dynamics associated with intermediate formation in an archetypal conformational disease. Structure , 20 (3) 504 - 512. 10.1016/j.str.2012.01.012.

Oseni, A; Crowley, C; Seifalian, AM; Lowdell, M; Birchall, M; Butler, PE; (2012) Advancing nasal reconstructive surgery: The application of tissue engineering technology. Journal of Tissue Engineering and Regenerative Medicine , 6 (10) 757 - 768. 10.1002/term.487.

Payne, EM; Virgilio, M; Narla, A; Sun, H; Levine, M; Paw, BH; ... Khanna-Gupta, A; + view all (2012) L-Leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway. Blood , 120 (11) 2214 - 2224. 10.1182/blood-2011-10-382986.

Qiu, W; Baccarelli, A; Carey, VJ; Boutaoui, N; Bacherman, H; Klanderman, B; ... DeMeo, DL; + view all (2012) Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function. Am J Respir Crit Care Med , 185 (4) 373 - 381. 10.1164/rccm.201108-1382OC.

Raja, FA; Hook, JM; Ledermann, JA; (2012) Biomarkers in the development of anti-angiogenic therapies for ovarian cancer. Cancer Treat Rev , 38 (6) 662 - 672. 10.1016/j.ctrv.2011.11.009.

Ramage, JK; Ahmed, A; Ardill, J; Bax, N; Breen, DJ; Caplin, ME; ... Grossman, AB; + view all (2012) Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs). GUT , 61 (1) 6 - 32. 10.1136/gutjnl-2011-300831.

Ramasubramanyan, S; Kanhere, A; Osborn, K; Flower, K; Jenner, RG; Sinclair, AJ; (2012) Genome-wide analyses of Zta binding to the Epstein-Barr virus genome reveals interactions in both early and late lytic cycles and an epigenetic switch leading to an altered binding profile. J Virol , 86 (23) 12494 - 12502. 10.1128/JVI.01705-12.

Rashid, ST; Lomas, DA; (2012) Stem cell-based therapy for α₁-antitrypsin deficiency. Stem Cell Res Ther , 3 (1) 4 - ?. 10.1186/scrt95.

Ruers, T; Punt, C; Van Coevorden, F; Pierie, JP; Borel-Rinkes, I; Ledermann, JA; ... EORTC Gastro-Intestinal Tract Cancer Group, Arbeitsgruppe Lebermetastasen und—tumoren in der Chirurgischen Arbeitsgemeinschaft Onkologie (ALM-CAO) and the National Cancer Research Institute Colorectal Clinical Study Group (NCRI CCSG),; + view all (2012) Radiofrequency ablation combined with systemic treatment versus systemic treatment alone in patients with non-resectable colorectal liver metastases: a randomized EORTC Intergroup phase II study (EORTC 40004). Ann Oncol , 23 (10) 2619 - 2626. 10.1093/annonc/mds053.

Schmid, ST; Koepke, J; Dresel, M; Hattesohl, A; Frenzel, E; Perez, J; ... Koczulla, AR; + view all (2012) The effects of weekly augmentation therapy in patients with PiZZ α1-antitrypsin deficiency. Int J Chron Obstruct Pulmon Dis , 7 687 - 696. 10.2147/COPD.S34560.

Sellar, RS; Peggs, KS; (2012) Therapeutic strategies for the prevention and treatment of cytomegalovirus infection. Expert Opin Biol Ther , 12 (9) 1161 - 1172. 10.1517/14712598.2012.693471.

Sive, JI; Buck, G; Fielding, A; Lazarus, HM; Litzow, MR; Luger, S; ... Goldstone, AH; + view all (2012) Outcomes in older adults with acute lymphoblastic leukaemia (ALL): results from the international MRC UKALL XII/ECOG2993 trial. Br J Haematol , 157 (4) 463 - 471. 10.1111/j.1365-2141.2012.09095.x.

Slater, S; Witteveen, PO; Plummer, R; Kristeleit, R; Evans, TRJ; Reyderman, L; ... Schellens, JHM; + view all (2012) 599 Effect of Food On Relative Bioavailability of E7820 in Cancer Patients. European Journal of Cancer , 48 , Article S6. 10.1016/S0959-8049(12)72396-1.

Speretta, E; Jahn, TR; Tartaglia, GG; Favrin, G; Barros, TP; Imarisio, S; ... Dobson, CM; + view all (2012) Expression in drosophila of tandem amyloid β peptides provides insights into links between aggregation and neurotoxicity. J Biol Chem , 287 (24) 20748 - 20754. 10.1074/jbc.M112.350124.

Spruit, MA; Polkey, MI; Celli, B; Edwards, LD; Watkins, ML; Pinto-Plata, V; ... Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) study investigators,; + view all (2012) Predicting outcomes from 6-minute walk distance in chronic obstructive pulmonary disease. J Am Med Dir Assoc , 13 (3) 291 - 297. 10.1016/j.jamda.2011.06.009.

Stolk, J; Stockley, RA; Stoel, BC; Cooper, BG; Piitulainen, E; Seersholm, N; ... Rames, A; + view all (2012) Randomised controlled trial for emphysema with a selective agonist of the γ-type retinoic acid receptor. Eur Respir J , 40 (2) 306 - 312. 10.1183/09031936.00161911.

Taiwo, O; Wilson, GA; Morris, T; Seisenberger, S; Reik, W; Pearce, D; ... Butcher, LM; + view all (2012) Methylome analysis using MeDIP-seq with low DNA concentrations. Nat Protoc , 7 (4) 617 - 636. 10.1038/nprot.2012.012.

Ubhi, BK; Cheng, KK; Dong, J; Janowitz, T; Jodrell, D; Tal-Singer, R; ... Connor, SC; + view all (2012) Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD. Mol Biosyst , 8 (12) 3125 - 3133. 10.1039/c2mb25194a.

Ubhi, BK; Riley, JH; Shaw, PA; Lomas, DA; Tal-Singer, R; MacNee, W; ... Connor, SC; + view all (2012) Metabolic profiling detects biomarkers of protein degradation in COPD patients. Eur Respir J , 40 (2) 345 - 355. 10.1183/09031936.00112411.

van der Harst, P; Zhang, W; Mateo Leach, I; Rendon, A; Verweij, N; Sehmi, J; ... Chambers, JC; + view all (2012) Seventy-five genetic loci influencing the human red blood cell. Nature , 492 (7429) 369 - 375. 10.1038/nature11677.

Wan, ES; Qiu, W; Baccarelli, A; Carey, VJ; Bacherman, H; Rennard, SI; ... DeMeo, DL; + view all (2012) Systemic steroid exposure is associated with differential methylation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med , 186 (12) 1248 - 1255. 10.1164/rccm.201207-1280OC.

Wan, ES; Qiu, W; Baccarelli, A; Carey, VJ; Bacherman, H; Rennard, SI; ... Demeo, DL; + view all (2012) Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome. Hum Mol Genet , 21 (13) 3073 - 3082. 10.1093/hmg/dds135.

Wilk, JB; Shrine, NR; Loehr, LR; Zhao, JH; Manichaikul, A; Lopez, LM; ... Stricker, BH; + view all (2012) Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Am J Respir Crit Care Med , 186 (7) 622 - 632. 10.1164/rccm.201202-0366OC.

Windsor, RE; Strauss, SJ; Kallis, C; Wood, NE; Whelan, JS; (2012) Germline Genetic Polymorphisms May Influence Chemotherapy Response and Disease Outcome in Osteosarcoma. CANCER , 118 (7) 1856 - 1867. 10.1002/cncr.26472.

Young, RJ; Tin, AW; Brown, NJ; Jitlal, M; Lee, SM; Woll, PJ; (2012) Analysis of circulating angiogenic biomarkers from patients in two phase III trials in lung cancer of chemotherapy alone or chemotherapy and thalidomide. Br J Cancer , 106 (6) 1153 - 1159. 10.1038/bjc.2012.50.

Zhuang, J; Widschwendter, M; Teschendorff, AE; (2012) A comparison of feature selection and classification methods in DNA methylation studies using the Illumina Infinium platform. BMC Bioinformatics , 13 59 - ?. 10.1186/1471-2105-13-59. Gold open access

Book chapter

Lowdell, MW; Samuel, E; (2012) Processing of Cells for Transplantation. In: UNSPECIFIED (271 - 292).

Proceedings paper

Fishman, J; Ansari, T; Sibbons, P; Lowdell, M; De Coppi, P; Birchall, M; (2012) Characterisation and immunogenicity of a decellularised skeletal muscle scaffold for laryngeal tissue engineering. In: JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE. (pp. 174 - 174).

Jenkinson, S; Koo, K; Goulden, N; Vora, A; Mitchell, C; Wade, R; ... Gale, RE; + view all (2012) Presence of mutations in the NOTCH1 signalling pathway has a beneficial impact on outcome in paediatric T-ALL patients treated on the MRC UKALL2003 trial. In: BRITISH JOURNAL OF HAEMATOLOGY. (pp. 19 - 20).

Knight, A; Arnouk, H; Gillespie, G; Britt, W; Su, Y; Lowdell, MW; Lamb, LS; (2012) CYTOMEGALOVIRUS-INDEPENDENT LYSIS OF GLIOMA-DERIVED CELL LINES AND PRIMARY TUMOR EXPLANTS BY IN VITRO EXPANDED/ACTIVATED V Delta 1+Gamma Delta T CELLS. In: NEURO-ONCOLOGY. (pp. 38 - 38).

Sabry, M; Lowdell, MW; (2012) Natural Killer Cell Responses to Tumor Priming. In: EUROPEAN JOURNAL OF CANCER. (pp. S86 - S86).

Shepherd, C; Banerjee, L; Cheung, CW; Mansour, MR; Jenkinson, S; Gale, RE; Khwaja, A; (2012) PI3K/mTOR Inhibition Upregulates NOTCH-MYC Signalling Leading to an Impaired Cytotoxic Response. In: BLOOD.

Thesis

Jagroop-Dearing, I.A.; (2012) Effect of antithrombotic drugs on platelet function and receptors and an investigation into platelet cholesterol. Doctoral thesis, UCL (University College London). Green open access
file

This list was generated on Sun Oct 26 02:31:07 2014 GMT.