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Number of items: 56.

A

Al-Mufti, RAM and Pedley, RB and Marshall, RB and Begent, RHJ and Winslet, MCAH and K, EF (1996) In vitro assessment of Lipiodol targeted radiotherapy for primary and metastatic liver cancers. In: (Proceedings) Proceedings BACR, Br J Cancer. (pp. 20 - ?).

Anlezark, GM and Cook, R and Melton, RG and Freemantle, P and Pedley, RB and Boden, J and Knox, RJ (1996) Biodistribution of A5B7 F(ab')2: E coli B nitroreductase conjugate in nude mice with human xenografts. In: (Proceedings) Proceedings BACR, Br J Cancer. (pp. 40 - ?).

Arris, CE and Bleasdale, C and Boyle, FT and Calvert, AH and Curtin, NJ and Dalby, C and Golding, BT and Griffin, RJ and Lembicz, N and Lunn, JM and Major, GN and Newell, DR (1996) Mechanism-based inhibition of O-6-methylguanine-DNA methyltransferase. ABSTR PAP AM CHEM S , 212 99 - TOXI.

B

Begent, RHJ and Chester, KA (1996) Single chain Fv antibodies for targeting cancer therapy. In: Immunology. (pp. SI113 - SI113).

Begent, RHJ and Verhaar, MJ and Chester, KA and Casey, JL and Green, AJ and Napier, MP and Hopstone, LD and Cushen, N and Keep, PA and Johnson, CJ and Hawkins, RE and Hilson, AJW and Robson, L (1996) Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library. Nature Medicine , 2 (9) 979 - 984.

Bingham, JP and Hartley, JA and Souhami, RL and Grimaldi, KA (1996) Strand-specific measurement of cisplatin-induced DNA damage and repair using quantitative PCR. NUCLEIC ACIDS RES , 24 (5) 987 - 989.
An open access publication

Butler, J and Spanswick, VJ and Cummings, J (1996) The autoxidation of the reduced forms of EO9. FREE RADICAL RES , 25 (2) 141 - 148.

C

Carney, DN and Bunn, PA and Belani, CP and Giaccone, and Shepherd, FA and Calvert, AH and Comis, RL and Splinter, TAW and Ettinger, DS and Johnson, DH and Langer, CJ and Greco, FA and Hainsworth, JD and Bonomi, P and Curran, WJ and Choy, H and Glantz, MJ (1996) Discussion: Lung cancer. SEMIN ONCOL , 23 (6) 140 - 147.

Casey, JL and King, DJ and Chaplin, LC and Haines, AMR and Pedley, RB and Mountain, A and Yarranton, GT and Begent, RHJ (1996) Preparation, characterisation and tumour targeting of cross-linked divalent and trivalent anti-tumour Fab' fragments. BRIT J CANCER , 74 (9) 1397 - 1405.

Chester, KA and Hawkins, RE (1996) Opportunities with phage technology and antibody engineering of fusion proteins. Advanced Drug Delivery Reviews , 22 (3) 303 - 313.

D

Dahl, AM and Beverley, PCL and Stauss, HJ (1996) A synthetic peptide derived from the tumor-associated protein mdm2 can stimulate autoreactive, high avidity cytotoxic T lymphocytes that recognize naturally processed protein. J IMMUNOL , 157 (1) 239 - 246.

Delgado, C and Pedley, RB and Herraez, A and Boden, R and Boden, JA and Keep, PA and Chester, KA and Fisher, D and Begent, RHJ and Francis, GE (1996) Enhanced tumour specificity of an anti-carcinoembrionic antigen Fab' fragment by poly(ethylene glycol) (PEG) modification. BRIT J CANCER , 73 (2) 175 - 182.

G

GhazalAswad, S and Calvert, AH and Newell, DR (1996) A single sample assay for the estimation of the area under the free carboplatin plasma concentration versus time curve. CANCER CHEMOTH PHARM , 37 (5) 429 - 434.

GhazalAswad, S and Hogarth, L and Hall, AG and George, M and Sinha, DP and Lind, M and Calvert, AH and Sunter, JP and Newell, DR (1996) The relationship between tumour glutathione concentration, glutathione S-transferase isoenzyme expression and response to single agent carboplatin in epithelial ovarian cancer patients. BRIT J CANCER , 74 (3) 468 - 473.

Gombert, W and Borthwick, NJ and Wallace, DL and Hyde, H and Bofill, M and Pilling, D and Beverley, PCL and Janossy, G and Salmon, M and Akbar, AN (1996) Fibroblasts prevent apoptosis of IL-2-deprived T cells without inducing proliferation: A selective effect on Bcl-x(L) expression. IMMUNOLOGY , 89 (3) 397 - 404.

H

Hawkins, RE and Chester, KA (1996) Applications of antibody gene technology. In: Dalgleish, AG and Browning, MJ, (eds.) Tumour Immunology. Cambridge University Press

Henstra, SA and Tolner, B and Duurkens, RHT and Konings, WN and Robillard, GT (1996) Cloning, expression, and isolation of the mannitol transport protein from the thermophilic bacterium Bacillus stearothermophilus. J BACTERIOL , 178 (19) 5586 - 5591.

Hochhauser, D and Schnieders, B and ErcikanAbali, E and Gorlick, R and MuiseHelmericks, R and Li, WW and Fan, JG and Banerjee, D and Bertino, JR (1996) Effect of cyclin D1 overexpression on drug sensitivity in a human fibrosarcoma cell line. J NATL CANCER I , 88 (18) 1269 - 1275.

K

Köberle, B and Payne, J and Grimaldi, KA and Hartley, JA and Masters, JR (1996) DNA repair in cisplatin-sensitive and resistant human cell lines measured in specific genes by quantitative polymerase chain reaction. Biochem Pharmacol , 52 (11) 1729 - 1734.

L

Laohavinij, S and Wedge, SR and Lind, MJ and Bailey, N and Humphrey, A and Proctor, M and Chapman, F and Simmons, D and Oakley, A and Robson, L and Gumbrell, L and Taylor, GA and Thomas, HD and Boddy, AV and Newell, DR and Calvert, AH (1996) A Phase I clinical study of the antipurine antifolate lometrexol (DDATHF) given with oral folic acid. INVEST NEW DRUG , 14 (3) 325 - 335.

Lee, M and Simpson, JE and Burns, AJ and Kupchinsky, S and Brooks, N and Hartley, JA and Kelland, LR (1996) Novel platinum(II) derivatives of analogues of netropsin and distamycin: Synthesis, DNA binding and cytotoxic properties. MED CHEM RES , 6 (6) 365 - 371.

Lee, SM and Portmann, B and Margison, GP (1996) Abnormal intracellular distribution of 06-alkylguanine-DNA-alkyltransferase in hepatitis B cirrhotic human liver: A potential cofactor in the development of hepatocellular carcinoma. Hepatology , 24 (5) 987 - 990.

Lee, SM and Portmann, B and Margison, GP (1996) Abnormal intracellular distribution of 06-alkylguanine-DNA-alkyltransferase in hepatitis-B cirrhotic human liver: a potential cofactor in the development of hepatocellular carcinoma. In: Paterson Annual Research Report. (pp. 24 - ?).

Lee, SM and Radford, JA and Ryder, WDJ and Crowther, D (1996) Prognostic factors for disease progression in advanced Hodgkin's disease. In: (Proceedings) VIth International Conference on Malignant Lymphoma, Lugano.. (pp. 52 - ?). Annals of Oncology

Lee, SM and Reid, H and Elder, RH and Thatcher, N and Margison, GP (1996) Inter- and intracellular heterogeneity of O6-alkylguanine-DNA alkyltransferase expression in human brain tumors: possible significance in nitrosourea therapy. Carcinogenesis , 17 (4) 637 - 641.

Lind, MJ and GhazalAswad, S and Gumbrell, L and Fishwick, K and Craigs, D and Millward, MJ and Bailey, NP and DoreGreen, F and Chapman, F and Simmons, D and Proctor, M and Oakey, A and Robson, L and Middleton, I and McCann, E and Sinha, D and Calvert, AH (1996) Phase I study of pharmacologically based dosing of carboplatin with filgrastim support in women with epithelial ovarian cancer. J CLIN ONCOL , 14 (3) 800 - 805.

Loflin, PT and Altschuler, E and Hochhauser, D and Hickson, ID and Zwelling, LA (1996) Phorbol ester-induced down-regulation of topoisomerase II alpha mRNA in a human erythroleukemia cell line - Evidence for a post-transcriptional mechanism. BIOCHEM PHARMACOL , 52 (7) 1065 - 1072.

M

Margison, GP and Rafferty, JA and Elder, RH and Kelly, J and Watson, AJ and Willington, MA and Lee, SM and Hickson, I and Fairbaim, LJ and Dexter, TM and Jelinek, J and Stocking, C and Baum, C and Ostertag, W and Eghyazi, S and Hansson, J and Ringborg, U and Donnelly, D and McMurry, TBH and McCormick, J and McElhinney, RS (1996) Modulating nitrosourea response in tumors and normal tissue: application to fotemustine. Drugs of Today , 32 (Jan) 51 - 59.

Marshall, D and Pedley, RB and Boden, J and Boden, R and Melton, RGAB and R, HJ (1996) Effect of polyethylene glycol modification of a galactosylated streptavidin clearing agent on immunogenicity and clearance of a biotinylated anti-tumour antibody. In: (Proceedings) Proceedings BACR, Br J Cancer. (pp. 71 - ?).

Marshall, D and Pedley, RB and Boden, JA and Boden, R and Melton, RG and Begent, RHJ (1996) Polyethylene glycol modification of a galactosylated streptavidin clearing agent: Effects on immunogenicity and clearance of a biotinylated anti-tumour antibody. BRIT J CANCER , 73 (5) 565 - 572.

Mayalarp, SP and Hargreaves, RHJ and Butler, J and OHare, CC and Hartley, JA (1996) Cross-linking and sequence specific alkylation of DNA by aziridinylquinones .1.. Quinone methides. J MED CHEM , 39 (2) 531 - 537.

Michael, NP and Chester, KA and Melton, RG and Robson, L and Nicholas, W and Boden, JA and Pedley, RB and Begent, RHJ and Sherwood, RF and Minton, NP (1996) In vitro and in vivo characterisation of a recombinant carboxypeptidase G(2)::anti-CEA scFv fusion protein. IMMUNOTECHNOLOGY , 2 (1) 47 - 57.

Mummaneni, V and Kaul, S and Igwemezie, LN and Newell, DR and Porter, D and Thomas, H and Calvert, AH and Winograd, B and Barbhaiya, RH (1996) Bioequivalence assessment of etoposide phosphate and etoposide using pharmacodynamic and traditional pharmacokinetic parameters. J PHARMACOKINET BIOP , 24 (4) 313 - 325.

O

Ornadel, D and Ledermann, JA and Ward, SE and Eagle, K and Pedley, RB and Olabrian, Y and and Bromanji, J (1996) Localisation of intact and F(ab')2 fragments of NY3D11, a monoclonal antibody recognising the neural cell adhesion molecule on small cell lung cancer. In: (Proceedings) Proceedings BACR, Br J Cancer. (pp. 70 - ?).

P

Pappa, VI and Hussain, HK and Reznek, RL and Whelan, JS and Norton, AJ and Wilson, AM and Love, S and Lister, TA and Rohatiner, AZS (1996) Role of image-guided core-needle biopsy in the management of patients with lymphoma. Journal of Clinical Oncology , 14 2427 - 2430.

Pedley, RB (1996) Pharmacokinetics of monoclonal antibodies - Implications for their use in cancer therapy. CLIN IMMUNOTHER , 6 (1) 54 - 67.

Pedley, RB and Boden, J and Boden, R and Boxer, GM and and Begent, RHJ (1996) Enhancement of radioimmunotherapy by tumour blood flow modifying agents. In: (Proceedings) Proceedings BACR, Br J Cancer. (pp. 70 - ?).

Pedley, RB and Boden, JA and Boden, R and Boxer, GM and Flynn, AA and Keep, PA and Begent, RHJ (1996) Ablation of colorectal xenografts with combined radioimmunotherapy and tumor blood flow-modifying agents. CANCER RES , 56 (14) 3293 - 3300.

Porter, D and Boddy, A and Thomas, H and Lind, M and Newell, D and Calvert, AH and Robson, L and Brampton, M and Abrahamsen, D and Winograd, B (1996) Etoposide phosphate infusion with therapeutic drug monitoring in combination with carboplatin dosed by area under the curve: A cancer research campaign phase I/II committee study. SEMIN ONCOL , 23 (6) 34 - 44.

S

Sandri, MI and Hochhauser, D and Ayton, P and Camplejohn, RC and Whitehouse, R and Turley, H and Gatter, K and Hickson, ID and Harris, AL (1996) Differential expression of the topoisomerase II alpha and beta genes in human breast cancers. BRIT J CANCER , 73 (12) 1518 - 1524.

Seidman, AD and Hochhauser, D and Gollub, M and Edelman, B and Yao, TJ and Hudis, CA and Francis, P and Fennelly, D and Gilewski, TA and Moynahan, ME and Currie, V and Baselga, J and Tong, W and ODonaghue, M and Salvaggio, R and Auguste, L and Spriggs, D and Norton, L (1996) Ninety-six-hour paclitaxel infusion after progression during short taxane exposure: A phase II pharmacokinetic and pharmacodynamic study in metastatic breast cancer. J CLIN ONCOL , 14 (6) 1877 - 1884.

Short, S and Chatterverdi, A and Leslie, M (1996) The treatment of adrenal metastases. Clinical Oncology , 8 387 - 389.

Sigalas, I and Calvert, AH and Anderson, JJ and Neal, DE and Lunec, J (1996) Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: Transforming ability and frequent detection in human cancer. NAT MED , 2 (8) 912 - 917.

Souhami, RL and Whelan, JS and McCarthy, D and Kilby, A (1996) Benefits and problems of an Adolescent Oncology Unit. In: Selby, P and Bailey, C, (eds.) Cancer and the Adolescent. BMJ Publishing Group: London.

Spanswick, VJ and Cummings, J and Smyth, JF (1996) Enzymology of mitomycin C metabolic activation in tumour tissue - Characterization of a novel mitochondrial reductase. BIOCHEM PHARMACOL , 51 (12) 1623 - 1630.

Springer, CJ and Bavetsias, V and Jackman, AL and Boyle, FT and Marshall, D and Pedley, RB and Bisset, GMF (1996) Prodrugs of thymidylate synthase inhibitors: Potential for antibody directed enzyme prodrug therapy (ADEPT). ANTI-CANCER DRUG DES , 11 (8) 625 - 636.

Sunters, A and Grimaldi, KA and Souhami, RL and Hartley, JA (1996) The use of alpha-DNA as an internal standard in the detection and quantitation of DNA damage in specific genes using Southern blotting. NUCLEIC ACIDS RES , 24 (12) 2456 - 2457.
An open access publication

T

Thurston, DE and Bose, DS and Thompson, AS and Howard, PW and Leoni, A and Croker, SJ and Jenkins, TC and Neidle, S and Hartley, JA and Hurley, LH (1996) Synthesis of sequence-selective C8-linked pyrrolo[2,1-c][1,4]benzodiazepine DNA interstrand cross-linking agents. J ORG CHEM , 61 (23) 8141 - 8147.

Thurston, DE and Morris, SJ and Hartley, JA (1996) Synthesis of a novel GC-specific covalent-binding DNA affinity-cleavage agent based on pyrrolobenzodiazepines (PBDs). CHEM COMMUN (4) 563 - 565.

V

Verhaar, MJ and Keep, PA and Hawkins, RE and Robson, L and Casey, JL and Pedley, B and Boden, JA and Begent, RHJ and Chester, KA (1996) Technetium-99m radiolabeling using a phage-derived single-chain Fv with a C-terminal cysteine. Journal of Nuclear Medicine , 37 (5) 868 - 872.

W

Whelan, JS and Denby, K and Cassoni, AM and Souhami, and RL, (1996) High dose chemotherapy with bone marrow or peripheral stem cell rescue for metastatic or recurrent Ewing's sarcoma. In: European Musculoskeletal Oncology Society Meeting, Oct 1996.

Whelan, JS and Dhawan, R and Pringle, J and Bomanji, J and Souhami, RL (1996) Quantitative, serial, pre-operative thallium scans correlate with histological response to neo-adjuvant chemotherapy in osteosarcoma. In: 2nd Osteosarcoma Research Conference, Nov 1996.

Whelan, JS and Kakouri, E and Souhami, RL (1996) Carboplatin-based combination chemotherapy in progressive or recurrent Ewing's sarcoma and primitive neuroectodermal tumours. In: BACR/EACR/ACP Annual Meeting, April 1996.

Whelan, JS and Souhami, RL (1996) High dose therapy (HDT) with melphalan (M) and total body irradiation (TBI) or busulphan (B) for Ewing's sarcoma (ES). BRIT J CANCER , 73 (8) 27 - 27.

Woll, PJ and Lee, SM and Lomax, L and Hodgetts, J and Stout, R and Burn, PA and Sims, T and Kitchin, R and Thatcher, N (1996) Randomised phase II study of standard versus dose-intensive ICE chemotherapy with reinfusion of haemopoietic progenitors in whole blood in small cell lung cancer (SCLC). In: (Proceedings) Oral presentation. 1996 ASCO Annual Meeting, Philadelphia, Pennsylvania.. (pp. 333 - ?). Proceedings of the American Society of Clinical Oncology

Wotherspoon, AC and Diss, TC and Pan, L and Singh, N and Whelan, JS and Isaacson, PG (1996) Low grade B-cell lymphoma of mucosa associated lymphoid tissue in immunocompromised patients. Histopathology , 28 129 - 134.

This list was generated on Mon May 20 06:59:04 2013 BST.