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Number of items: 58.


Al-Mufti, RAM; Pedley, RB; Marshall, RB; Begent, RHJ; Winslet, MCAH; K, EF; (1996) In vitro assessment of Lipiodol targeted radiotherapy for primary and metastatic liver cancers. In: (Proceedings) Proceedings BACR, Br J Cancer. (pp. 20 - ?).

Anlezark, GM; Cook, R; Melton, RG; Freemantle, P; Pedley, RB; Boden, J; Knox, RJ; (1996) Biodistribution of A5B7 F(ab')2: E coli B nitroreductase conjugate in nude mice with human xenografts. In: (Proceedings) Proceedings BACR, Br J Cancer. (pp. 40 - ?).

Arris, CE; Bleasdale, C; Boyle, FT; Calvert, AH; Curtin, NJ; Dalby, C; ... Newell, DR; + view all (1996) Mechanism-based inhibition of O-6-methylguanine-DNA methyltransferase. ABSTR PAP AM CHEM S , 212 99 - TOXI.


Begent, RHJ; Chester, KA; (1996) Single chain Fv antibodies for targeting cancer therapy. In: Immunology. (pp. SI113 - SI113).

Begent, RHJ; Verhaar, MJ; Chester, KA; Casey, JL; Green, AJ; Napier, MP; ... Robson, L; + view all (1996) Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library. Nature Medicine , 2 (9) 979 - 984.

Bingham, JP; Hartley, JA; Souhami, RL; Grimaldi, KA; (1996) Strand-specific measurement of cisplatin-induced DNA damage and repair using quantitative PCR. NUCLEIC ACIDS RES , 24 (5) 987 - 989. Gold open access

Butler, J; Spanswick, VJ; Cummings, J; (1996) The autoxidation of the reduced forms of EO9. FREE RADICAL RES , 25 (2) 141 - 148.


Carney, DN; Bunn, PA; Belani, CP; Giaccone,; Shepherd, FA; Calvert, AH; ... Glantz, MJ; + view all (1996) Discussion: Lung cancer. SEMIN ONCOL , 23 (6) 140 - 147.

Casey, JL; King, DJ; Chaplin, LC; Haines, AMR; Pedley, RB; Mountain, A; ... Begent, RHJ; + view all (1996) Preparation, characterisation and tumour targeting of cross-linked divalent and trivalent anti-tumour Fab' fragments. BRIT J CANCER , 74 (9) 1397 - 1405.

Chester, KA; Hawkins, RE; (1996) Opportunities with phage technology and antibody engineering of fusion proteins. Advanced Drug Delivery Reviews , 22 (3) 303 - 313.


Dahl, AM; Beverley, PCL; Stauss, HJ; (1996) A synthetic peptide derived from the tumor-associated protein mdm2 can stimulate autoreactive, high avidity cytotoxic T lymphocytes that recognize naturally processed protein. J IMMUNOL , 157 (1) 239 - 246.

Delgado, C; Pedley, RB; Herraez, A; Boden, R; Boden, JA; Keep, PA; ... Francis, GE; + view all (1996) Enhanced tumour specificity of an anti-carcinoembrionic antigen Fab' fragment by poly(ethylene glycol) (PEG) modification. BRIT J CANCER , 73 (2) 175 - 182.


GhazalAswad, S; Calvert, AH; Newell, DR; (1996) A single sample assay for the estimation of the area under the free carboplatin plasma concentration versus time curve. CANCER CHEMOTH PHARM , 37 (5) 429 - 434.

GhazalAswad, S; Hogarth, L; Hall, AG; George, M; Sinha, DP; Lind, M; ... Newell, DR; + view all (1996) The relationship between tumour glutathione concentration, glutathione S-transferase isoenzyme expression and response to single agent carboplatin in epithelial ovarian cancer patients. BRIT J CANCER , 74 (3) 468 - 473.

Gombert, W; Borthwick, NJ; Wallace, DL; Hyde, H; Bofill, M; Pilling, D; ... Akbar, AN; + view all (1996) Fibroblasts prevent apoptosis of IL-2-deprived T cells without inducing proliferation: A selective effect on Bcl-x(L) expression. IMMUNOLOGY , 89 (3) 397 - 404.


Hawkins, RE; Chester, KA; (1996) Applications of antibody gene technology. In: Dalgleish, AG and Browning, MJ, (eds.) Tumour Immunology. Cambridge University Press

Henstra, SA; Tolner, B; Duurkens, RHT; Konings, WN; Robillard, GT; (1996) Cloning, expression, and isolation of the mannitol transport protein from the thermophilic bacterium Bacillus stearothermophilus. J BACTERIOL , 178 (19) 5586 - 5591.


Köberle, B; Payne, J; Grimaldi, KA; Hartley, JA; Masters, JR; (1996) DNA repair in cisplatin-sensitive and resistant human cell lines measured in specific genes by quantitative polymerase chain reaction. Biochem Pharmacol , 52 (11) 1729 - 1734.


Laohavinij, S; Wedge, SR; Lind, MJ; Bailey, N; Humphrey, A; Proctor, M; ... Calvert, AH; + view all (1996) A Phase I clinical study of the antipurine antifolate lometrexol (DDATHF) given with oral folic acid. INVEST NEW DRUG , 14 (3) 325 - 335.

Lee, M; Simpson, JE; Burns, AJ; Kupchinsky, S; Brooks, N; Hartley, JA; Kelland, LR; (1996) Novel platinum(II) derivatives of analogues of netropsin and distamycin: Synthesis, DNA binding and cytotoxic properties. MED CHEM RES , 6 (6) 365 - 371.

Lee, SM; Portmann, B; Margison, GP; (1996) Abnormal intracellular distribution of 06-alkylguanine-DNA-alkyltransferase in hepatitis B cirrhotic human liver: A potential cofactor in the development of hepatocellular carcinoma. Hepatology , 24 (5) 987 - 990.

Lee, SM; Portmann, B; Margison, GP; (1996) Abnormal intracellular distribution of 06-alkylguanine-DNA-alkyltransferase in hepatitis-B cirrhotic human liver: a potential cofactor in the development of hepatocellular carcinoma. In: Paterson Annual Research Report. (pp. 24 - ?).

Lee, SM; Radford, JA; Ryder, WDJ; Crowther, D; (1996) Prognostic factors for disease progression in advanced Hodgkin's disease. In: (Proceedings) VIth International Conference on Malignant Lymphoma, Lugano.. (pp. 52 - ?). Annals of Oncology

Lee, SM; Reid, H; Elder, RH; Thatcher, N; Margison, GP; (1996) Inter- and intracellular heterogeneity of O6-alkylguanine-DNA alkyltransferase expression in human brain tumors: possible significance in nitrosourea therapy. Carcinogenesis , 17 (4) 637 - 641.

Lind, MJ; GhazalAswad, S; Gumbrell, L; Fishwick, K; Craigs, D; Millward, MJ; ... Calvert, AH; + view all (1996) Phase I study of pharmacologically based dosing of carboplatin with filgrastim support in women with epithelial ovarian cancer. J CLIN ONCOL , 14 (3) 800 - 805.

Loflin, PT; Altschuler, E; Hochhauser, D; Hickson, ID; Zwelling, LA; (1996) Phorbol ester-induced down-regulation of topoisomerase II alpha mRNA in a human erythroleukemia cell line - Evidence for a post-transcriptional mechanism. BIOCHEM PHARMACOL , 52 (7) 1065 - 1072.


Margison, GP; Rafferty, JA; Elder, RH; Kelly, J; Watson, AJ; Willington, MA; ... McElhinney, RS; + view all (1996) Modulating nitrosourea response in tumors and normal tissue: application to fotemustine. Drugs of Today , 32 (Jan) 51 - 59.

Marshall, D; Pedley, RB; Boden, J; Boden, R; Melton, RGAB; R, HJ; (1996) Effect of polyethylene glycol modification of a galactosylated streptavidin clearing agent on immunogenicity and clearance of a biotinylated anti-tumour antibody. In: (Proceedings) Proceedings BACR, Br J Cancer. (pp. 71 - ?).

Marshall, D; Pedley, RB; Boden, JA; Boden, R; Melton, RG; Begent, RHJ; (1996) Polyethylene glycol modification of a galactosylated streptavidin clearing agent: Effects on immunogenicity and clearance of a biotinylated anti-tumour antibody. BRIT J CANCER , 73 (5) 565 - 572.

Mayalarp, SP; Hargreaves, RHJ; Butler, J; OHare, CC; Hartley, JA; (1996) Cross-linking and sequence specific alkylation of DNA by aziridinylquinones .1.. Quinone methides. J MED CHEM , 39 (2) 531 - 537.

Mummaneni, V; Kaul, S; Igwemezie, LN; Newell, DR; Porter, D; Thomas, H; ... Barbhaiya, RH; + view all (1996) Bioequivalence assessment of etoposide phosphate and etoposide using pharmacodynamic and traditional pharmacokinetic parameters. J PHARMACOKINET BIOP , 24 (4) 313 - 325.


Ornadel, D; Ledermann, JA; Ward, SE; Eagle, K; Pedley, RB; Olabrian, Y; and Bromanji, J; (1996) Localisation of intact and F(ab')2 fragments of NY3D11, a monoclonal antibody recognising the neural cell adhesion molecule on small cell lung cancer. In: (Proceedings) Proceedings BACR, Br J Cancer. (pp. 70 - ?).


Pappa, VI; Hussain, HK; Reznek, RL; Whelan, JS; Norton, AJ; Wilson, AM; ... Rohatiner, AZS; + view all (1996) Role of image-guided core-needle biopsy in the management of patients with lymphoma. Journal of Clinical Oncology , 14 2427 - 2430.

Pedley, RB; (1996) Pharmacokinetics of monoclonal antibodies - Implications for their use in cancer therapy. CLIN IMMUNOTHER , 6 (1) 54 - 67.

Pedley, RB; Boden, J; Boden, R; Boxer, GM; and Begent, RHJ; (1996) Enhancement of radioimmunotherapy by tumour blood flow modifying agents. In: (Proceedings) Proceedings BACR, Br J Cancer. (pp. 70 - ?).

Pedley, RB; Boden, JA; Boden, R; Boxer, GM; Flynn, AA; Keep, PA; Begent, RHJ; (1996) Ablation of colorectal xenografts with combined radioimmunotherapy and tumor blood flow-modifying agents. CANCER RES , 56 (14) 3293 - 3300.

Porter, D; Boddy, A; Thomas, H; Lind, M; Newell, D; Calvert, AH; ... Winograd, B; + view all (1996) Etoposide phosphate infusion with therapeutic drug monitoring in combination with carboplatin dosed by area under the curve: A cancer research campaign phase I/II committee study. SEMIN ONCOL , 23 (6) 34 - 44.


Rodriguez-Viciana, P; Warne, PH; Vanhaesebroeck, B; Waterfield, MD; Downward, J; (1996) Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation. EMBO J , 15 (10) 2442 - 2451.


Sandri, MI; Hochhauser, D; Ayton, P; Camplejohn, RC; Whitehouse, R; Turley, H; ... Harris, AL; + view all (1996) Differential expression of the topoisomerase II alpha and beta genes in human breast cancers. BRIT J CANCER , 73 (12) 1518 - 1524.

Short, S; Chatterverdi, A; Leslie, M; (1996) The treatment of adrenal metastases. Clinical Oncology , 8 387 - 389.

Souhami, RL; Whelan, JS; McCarthy, D; Kilby, A; (1996) Benefits and problems of an Adolescent Oncology Unit. In: Selby, P and Bailey, C, (eds.) Cancer and the Adolescent. BMJ Publishing Group: London.

Spanswick, VJ; Cummings, J; Smyth, JF; (1996) Enzymology of mitomycin C metabolic activation in tumour tissue - Characterization of a novel mitochondrial reductase. BIOCHEM PHARMACOL , 51 (12) 1623 - 1630.

Springer, CJ; Bavetsias, V; Jackman, AL; Boyle, FT; Marshall, D; Pedley, RB; Bisset, GMF; (1996) Prodrugs of thymidylate synthase inhibitors: Potential for antibody directed enzyme prodrug therapy (ADEPT). ANTI-CANCER DRUG DES , 11 (8) 625 - 636.

Sunters, A; Grimaldi, KA; Souhami, RL; Hartley, JA; (1996) The use of alpha-DNA as an internal standard in the detection and quantitation of DNA damage in specific genes using Southern blotting. NUCLEIC ACIDS RES , 24 (12) 2456 - 2457. Gold open access


Thurston, DE; Morris, SJ; Hartley, JA; (1996) Synthesis of a novel GC-specific covalent-binding DNA affinity-cleavage agent based on pyrrolobenzodiazepines (PBDs). CHEM COMMUN (4) 563 - 565.


Vanhaesebroeck, B; Kotani, K; Stein, RC; Svolinia,; Downward, J; Waterfield, MD; (1996) PI 108, A novel human phosphoinositide 3-kinase. FASEB Journal , 10 (6)

Vanhaesebroeck, B; Stein, RC; Waterfield, MD; (1996) The study of phosphoinositide 3-kinase function. Cancer Surv , 27 249 - 270.

Verhaar, MJ; Keep, PA; Hawkins, RE; Robson, L; Casey, JL; Pedley, B; ... Chester, KA; + view all (1996) Technetium-99m radiolabeling using a phage-derived single-chain Fv with a C-terminal cysteine. Journal of Nuclear Medicine , 37 (5) 868 - 872.


Waterfield, MD; MacDougall, L; Gout, I; Vanhaesebroeck, B; Domin, J; Pages, F; ... Stein, R; + view all (1996) The PI 3 kinase family - Diversity in substrate specificity and activation mechanisms. FASEB JOURNAL , 10 (6) 1604 - 1604.

Whelan, JS; Denby, K; Cassoni, AM; Souhami,; RL,; (1996) High dose chemotherapy with bone marrow or peripheral stem cell rescue for metastatic or recurrent Ewing's sarcoma. In: European Musculoskeletal Oncology Society Meeting, Oct 1996.

Whelan, JS; Dhawan, R; Pringle, J; Bomanji, J; Souhami, RL; (1996) Quantitative, serial, pre-operative thallium scans correlate with histological response to neo-adjuvant chemotherapy in osteosarcoma. In: 2nd Osteosarcoma Research Conference, Nov 1996.

Whelan, JS; Kakouri, E; Souhami, RL; (1996) Carboplatin-based combination chemotherapy in progressive or recurrent Ewing's sarcoma and primitive neuroectodermal tumours. In: BACR/EACR/ACP Annual Meeting, April 1996.

Whelan, JS; Souhami, RL; (1996) High dose therapy (HDT) with melphalan (M) and total body irradiation (TBI) or busulphan (B) for Ewing's sarcoma (ES). BRIT J CANCER , 73 (8) 27 - 27.

Woll, PJ; Lee, SM; Lomax, L; Hodgetts, J; Stout, R; Burn, PA; ... Thatcher, N; + view all (1996) Randomised phase II study of standard versus dose-intensive ICE chemotherapy with reinfusion of haemopoietic progenitors in whole blood in small cell lung cancer (SCLC). In: (Proceedings) Oral presentation. 1996 ASCO Annual Meeting, Philadelphia, Pennsylvania.. (pp. 333 - ?). Proceedings of the American Society of Clinical Oncology

Wotherspoon, AC; Diss, TC; Pan, L; Singh, N; Whelan, JS; Isaacson, PG; (1996) Low grade B-cell lymphoma of mucosa associated lymphoid tissue in immunocompromised patients. Histopathology , 28 129 - 134.

Wymann, MP; Bulgarelli-Leva, G; Zvelebil, MJ; Pirola, L; Vanhaesebroeck, B; Waterfield, MD; Panayotou, G; (1996) Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction. Mol Cell Biol , 16 (4) 1722 - 1733.


Zvelebil, MJ; MacDougall, L; Leevers, S; Volinia, S; Vanhaesebroeck, B; Gout, I; ... Pages, F; + view all (1996) Structural and functional diversity of phosphoinositide 3-kinases. Philos Trans R Soc Lond B Biol Sci , 351 (1336) 217 - 223. 10.1098/rstb.1996.0019.

Zvelebil, MJ; MacDougall, L; Leevers, S; Volinia, S; Vanhaesebroeck, B; Gout, I; ... Waterfield, M; + view all (1996) Structural and functional diversity of phosphoinositide 3-kinases. In: PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. (pp. 217 - 223). ROYAL SOC LONDON

This list was generated on Sun Dec 14 07:39:05 2014 GMT.