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Number of items: 142.

A

Alley, MC and Hollingshead, MG and Pacula-Cox, CM and Waud, WR and Hartley, JA and Howard, PW and Gregson, SJ and Thurston, DE and Sausville, EA (2002) Efficacy evaluations of SJG-136 (NSC 694501), a novel pyrrolobenzodiazepine dimer with broad spectrum antitumor activity. In: Proc Am Assoc Cancer Res. (pp. 315 - ?).

Ardeshna, K and Smith, P and Norton, A and Hancock, B and Hoskin, PJ (2002) The long term impact of a watch and wait policy vs immediate systemic treatment for asymptomatic advanced stage indolent non Hodgkin's lymphoma: results of a British National Lymphoma randomized trial. In: Annals Of Oncology. (pp. 76 - ?).

Arkenau, H-T and Widjaja, A (2002) An unusual case of cholestasis and makrohematuria in a 52-year-old patient | Ein seltener fall von cholestase und makrohämaturie bei einem 52-jährigen patienen. Medizinische Klinik , 97 (8) 480 - 483.

Arkenau, HT and Stichtenoth, DO and Frölich, JC and Manns, MP and Böker, KH (2002) Elevated nitric oxide levels in patients with chronic liver disease and cirrhosis correlate with disease stage and parameters of hyperdynamic circulation. Z Gastroenterol , 40 (11) 907 - 913. 10.1055/s-2002-35413.

Arkenau, HT and Widjaja, A (2002) [A rare case of cholestasis and macrohematuria in a 52-year-old patient]. Med Klin (Munich) , 97 (8) 480 - 483.

Atalay, G and Biganzoli, L and Renard, F and Paridaens, R and Batter, V and Coleman, R and Piccart, M and Calvert, AH and Gamucci, T and Cofer, T (2002) Clinical outcome of breast cancer patients with liver metastases in the anthracycline-taxane era. Breast Cancer Research and Treatment , 76 138 - ?.

B

Baraldi, PG and Romagnoli, R and Guadix, AE and de las Infantas, MJP and Gallo, MA and Espinosa, A and Martinez, A and Bingham, JP and Hartley, JA (2002) Design, synthesis, and biological activity of hybrid compounds between uramustine and DNA minor groove binder distamycin A. J MED CHEM , 45 (17) 3630 - 3638. 10.1021/jm011113b.

Baraldi, PG and Romagnoli, R and Pavani, MG and Nunez, MD and Bingham, JP and Hartley, JA (2002) Benzoyl and cinnamoyl nitrogen mustard derivatives of benzoheterocyclic analogues of the tallimustine: Synthesis and antitumour activity. BIOORGAN MED CHEM , 10 (5) 1611 - 1618.

Baselga, J and Rischin, D and Ranson, M and Calvert, H and Raymond, E and Kieback, DG and Kaye, SB and Gianni, L and Harris, A and Bjork, T and Averbuch, SD and Feyereislova, A and Swaisland, H and Rojo, F and Albanell, J (2002) Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types. J CLIN ONCOL , 20 (21) 4292 - 4302. 10.1200/JCO.2002.03.100.

Batey, MA and Wright, JG and Azzabi, A and Newell, DR and Lind, MJ and Calvert, AH and Boddy, AV (2002) Population pharmacokinetics of adjuvant cyclophosphamide, methotrexate and 5-fluorouracil (CMF). EUR J CANCER , 38 (8) 1081 - 1089.

Beauregard, DA and Pedley, RB and Hill, SA and Brindle, KM (2002) Differential sensitivity of two adenocarcinoma xenografts to the anti-vascular drugs combretastatin A4 phosphate and 5,6-dimethylxanthenone-4-acetic acid, assessed using MRI and MRS. NMR BIOMED , 15 (2) 99 - 105. 10.1002/nbm.723.

Bentzen, SM and Saunders, MI and Dische, S (2002) From CHART to CHARTWEL in non-small cell lung cancer: Clinical radiobiological modelling of the expected change in outcome. Clinical Oncology , 14 (5) 372 - 381.

Biganzoli, L and Cufer, T and Bruning, P and Coleman, R and Duchateau, L and Calvert, AH and Gamucci, T and Twelves, C and Fargeot, P and Epelbaum, R and Lohrisch, C and Piccart, MJ (2002) Doxorubicin and paclitaxel versus doxorubicin and cyclophosphamide as first-line chemotherapy in metastatic breast cancer: The European Organization for Research and Treatment of Cancer 10961 multicenter phase III trial. J CLIN ONCOL , 20 (14) 3114 - 3121. 10.1200/JCO.2002.11.005.

Boddy, AV and Todd, R and Verrill, M and Sludden, J and Fishwick, K and Robson, L and Cassidy, J and Bisset, D and Garzone, PD and Calvert, AH (2002) Pharmacological study of CT-2103 (XyotaxTM), a poly(L-glutamic acid)-paclitaxel conjugate administered every 3 weeks or every 2 weeks in a phase I study. European Journal of Cancer , 38 98 - ?.

Bomanji, JB and Syed, R and Brock, C and Jankowska, P and Dogan, A and Costa, DC and Ell, PJ and Lee, SM (2002) Challenging cases and diagnostic dilemmas: case 2. Pitfalls of positron emission tomography for assessing residual mediastinal mass after chemotherapy for Hodgkin's disease. J Clin Oncol , 20 (15) 3347 - 3349.

Bowen, RL and Francis, RJ and Green, AJ and Baig, S and Knell, V and Buscombe, JR and Hilson, AJW and Begent, RHJ (2002) How accurately can the oncologist report FDG-PET tumour response using the ADAC vertex plus dual-headed gamma camera? British Journal of Cancer , 86 S102 - S102.

Braybrooke, JP and Slade, A and Gibson, R and Deplanque, G and Madhusudan, S and Makris, A (2002) Phase one study of MetXia-P450 gene therapy for patients with advanced breast cancer or melanoma. In: Proceedings ASCO. (pp. 22a - ?).

Brett, BT and Smith, SC and Bouvier, CV and Michaeli, D and Hochhauser, D and Davidson, BR and Kurzawinski, TR and Watkinson, AF and Van Someren, N and Pounder, RE and Caplin, ME (2002) Phase II study of anti-gastrin-17 antibodies, raised to G17DT, in advanced pancreatic cancer. J CLIN ONCOL , 20 (20) 4225 - 4231. 10.1200/JCO.2002.11.151.

Brock, CS and Lee, SM (2002) Anti-angiogenic strategies and vascular targeting in the treatment of lung cancer. Eur Respir J , 19 (3) 557 - 570.

Budhram-Mahadeo, V and Morris, P and Ndisang, D and Irshad, S and Lozano, G and Pedley, B and Latchman, DS (2002) The Brn-3a POU family transcription factor stimulates p53 gene expression in human and mouse tumour cells. NEUROSCI LETT , 334 (1) 1 - 4.

Bunn, PA and Calvert, H (2002) Pemetrexed, a novel multitargeted antifolate: Current development and future directions - Introduction. SEMIN ONCOL , 29 (2) 1 - 2. 10.1053/sonc.2002.30757.

Burcombe, RJ and Makris, A and Pittam, M and Lowe, J and Emmott, J and Wong, WL (2002) Evaluation of good clinical response to neoadjuvant chemotherapy in primary breast cancer using [F-18]- fluorodeoxyglucose positron emission tomography. European Journal of Cancer , 38 (3) 375 - 379.

Burcombe, RJ and Makris, A and Wilson, GD (2002) Evaluation of topoisomerase II-alpha as a predictor of clinical and pathological response to neoadjuvant chemotherapy in operable breast cancer. In: Proceedings ASCO. (pp. 447a - ?).

Burger, AM and Fiebig, HH and Hagan, DR and Tiberghien, A and Howard, PW and Schultz, R and Hartley, JA and Thurston, DE (2002) The monomer pyrrolobenzodiazepine (PBD) DNA minor-groove binding agent DRH-417 (NSC 709119) shows pre-clinical activity in human renal cell carcinoma. In: Proceedings of the American Association of Cancer Research. (pp. 5719 - ?).

C

Calvert, AH and Egorin, MJ (2002) Carboplatin dosing formulae: gender bias and the use of creatinine-based methodologies. EUR J CANCER , 38 (1) 11 - 16.

Calvert, H (2002) Folate status and the safety profile of antifolates. SEMINARS IN ONCOLOGY , 29 (2) 3 - 7. 10.1053/sonc.2002.30761.

Calvert, H and Bunn, PA (2002) Future directions in the development of pemetrexed. SEMINARS IN ONCOLOGY , 29 (2) 54 - 61. 10.1053/sonc.2002.30761.

Calvert, H and Jodrell, DI and Cassidy, J and Harris, AL (2002) Efficacy, safety, and cost of new anticancer drugs - Pessimistic conclusion was not justified. BRIT MED J , 325 (7375) 1302 - 1303.

Casey, JL and Napier, MP and King, DJ and Pedley, RB and Chaplin, LC and Weir, N and Skelton, L and Green, AJ and Hope-Stone, LD and Yarranton, GT and Begent, RH (2002) Tumour targeting of humanised cross-linked divalent-Fab' antibody fragments: a clinical phase I/II study. Br J Cancer , 86 (9) 1401 - 1410. 10.1038/sj.bjc.6600198.

Casey, JL and Napier, MP and King, DJ and Pedley, RB and Chaplin, LC and Weir, N and Skelton, L and Green, AJ and Hope-Stone, LD and Yarranton, GT and Begent, RHJ (2002) Tumour targeting of humanised cross-linked divalent-fab ' antibody fragments: a clinical phase I/II study. BRIT J CANCER , 86 (9) 1401 - 1410. 10.1038/sj/bjc/6600198.

Chow, E and Coia, L and Wu, J and Nanjan, N and Kirkbride, P and Hoskin, PJ (2002) Debate: this house believes that multiple-fraction radiotherapy is a barrier to referral for palliative radiotherapy for bone metastases. Current Oncology , 9 60 - 66.

Chow, E and Wu, JSY and Hoskin, P and Coia, LR and Bentzen, SM and Blitzer, PH (2002) International consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases. Radiotherapy And Oncology , 64 (3) 275 - 280.

Cooke, SP and Pedley, RB and Boden, R and Begent, RH and Chester, KA (2002) In vivo tumor delivery of a recombinant single chain Fv::tumor necrosis factor-alpha fusion [correction of factor: a fusion] protein. Bioconjug Chem , 13 (1) 7 - 15.

Cooke, SP and Pedley, RB and Boden, R and Begent, RHJ and Chester, KA (2002) In vivo tumor delivery of a recombinant single chain fv :: tumor necrosis factor-alpha fusion protein (vol 13, pg 7, 2002). BIOCONJUGATE CHEM , 13 (2) 385 - 385. 10.1021/bc020015h.

Cooke, SP and Pedley, RB and Boden, R and Begent, RHJ and Chester, KA (2002) In vivo tumor delivery of a recombinant single-chain Fv::Tumor necrosis factor: A fusion protein. Bioconjugate Chemistry , 13 (1) 7 - 15.

Cooke, SP and Pedley, RB and Boden, R and Begent, RHJ and Chester, KA (2002) In vivo tumor delivery of a recombinant single-chain Fv::Tumor necrosis factor: A fusion protein. BIOCONJUGATE CHEM , 13 (1) 7 - 15. 10.1021/bc000178a.

Craddock, C and Hochhauser, D (2002) Realising the potential of targeted therapies in oncology. LANCET , 360 (9331) 424 - 425.

D

De Silva, IU and McHugh, PJ and Clingen, PH and Hartley, JA (2002) Defects in interstrand cross-link uncoupling do not account for the extreme sensitivity of ERCC1 and XPF cells to cisplatin. NUCLEIC ACIDS RES , 30 (17) 3848 - 3856.
An open access publication

E

El Emir, E and Petrie, IA and Boxer, GM and Boden, R and Dearling, JLJ and Raleigh, JA and Mantavani, A and Green, AJ and Begent, RHJ and Pedley, RB (2002) Tumour parameters affected by combretastatin A-4 phosphate therapy in a human colorectal xenograft model in nude mice. British Journal of Cancer , 86 S112 - S112.

El-Emir, E and Petrie, and I, A and Boxer, and G, M and Boden, and R, and Dearling, and J, and Raleigh, and J, A and Mantovani, and A, and Green, and A, J and Begent, and R, HJAPRB (2002) Tumour parameters affected by combretastatin A-4 phosphate therapy in a human colorectal xenograft model in nude mice. In: (Proceedings) Proceedings BACR, Br J Cancer. (pp. 257 - ?).

El-Emir, E and Petrie, IA and Boxer, GM and Boden, R and Dearling, JLJ and Raleigh, JA and Mantavani, A and Green, AJ and Begent, RHJ and Pedley, RB (2002) Tumour parameters affected by combretastatin A-4 phosphate therapy in a human colorectal xenograft model in nude mice. BRIT J CANCER , 86 S112 - S112.

F

Flynn, AA and Green, AJ and Pedley, RB and Boxer, GM and Dearling, J and Watson, R and Boden, R and Begent, RH (2002) A model-based approach for the optimization of radioimmunotherapy through antibody design and radionuclide selection. Cancer , 94 (4 Suppl) 1249 - 1257.

Flynn, AA and Green, AJ and Pedley, RB and Boxer, GM and Dearling, J and Watson, R and Boden, R and Begent, RHJ (2002) A model-based approach for the optimization of radioimmunotherapy through antibody design and radionuclide selection. In: CANCER. (pp. 1249 - 1257). JOHN WILEY & SONS INC

Flynn, AA and Green, AJ and Pedley, RB and Boxer, GM and Dearling, J and Watson, R and Boden, RAB and R, HJ (2002) . A model-based approach for the optimization of radioimmunotherapy through antibody design and radionuclide selection. Cancer , 94 1249 - 1257.

Flynn, AA and Pedley, RB and Green, AJ and Boxer, GM and Boden, R and Bhatia, J and Morris, R and Begent, RHJ (2002) Antibody and radionuclide characteristics and the enhancement of the effectiveness of radioimmunotherapy by selective dose delivery to radiosensitive areas of tumour. International Journal of Radiation Biology , 78 (5) 407 - 415.

Flynn, AA and Pedley, RB and Green, AJ and Boxer, GM and Boden, R and Bhatia, J and Morris, R and Begent, RHJ (2002) Antibody and radionuclide characteristics and the enhancement of the effectiveness of radioimmunotherapy by selective dose delivery to radiosensitive areas of tumour. INT J RADIAT BIOL , 78 (5) 407 - 415. 10.1080/09553000110117818.

Flynn, AA and Pedley, RB and Green, AJ and Boxer, GM and Dearling, J and Boden, RABRHJ (2002) Antibody and radionuclide characteristics can enhance the effectiveness of radioimmunotherapy by selective dose delivery to radiosensitive areas of tumour. International Journal of Radiation Biology , 78 407 - 415.

Ford, HER and Mitchell, F and Cunningham, D and Farrugia, DC and Hill, ME and Rees, C and Calvert, AH and Judson, IR and Jackman, AL (2002) Patterns of elevation of plasma 2 '-deoxyuridine, a surrogate marker of thymidylate synthase (TS) inhibition, after administration of two different schedules of 5-fluorouracil and the specific TS inhibitors raltitrexed (Tomudex) and ZD9331. CLIN CANCER RES , 8 (1) 103 - 109.

Francis, RJ and Green, AJ and Baig, S and Knell, V and Frisken, I and Bowen, RL and Hilson, AJW and Buscombe, JR and Begent, RHJ (2002) A novel approach to assessing response to chemotherapy using hybrid camera FDG PET. British Journal of Cancer , 86 S100 - S100.

Francis, RJ and Sharma, SK and Springer, C and Green, AJ and Hope-Stone, LD and Sena, L and Martin, J and Adamson, KL and Robbins, A and Gumbrell, L and O'Malley, D and Tsiompanou, E and Shahbakhti, H and Webley, S and Hochhauser, D and Hilson, AJ and Blakey, D and Begent, RHJ (2002) A phase I trial of antibody directed enzyme prodrug therapy (ADEPT) in patients with advanced colorectal carcinoma or other CEA producing tumours. British Journal of Cancer , 87 (6) 600 - 607.

G

Gore, M and Oza, A and Rustin, G and Malfetano, J and Calvert, H and Clarke-Pearson, D and Carmichael, J and Ross, G and Beckman, RA and Fields, SZ (2002) A randomised trial of oral versus intravenous topotecan in patients with relapsed epithelial ovarian cancer. EUR J CANCER , 38 (1) 57 - 63.

Grimaldi, KA and McGurk, CJ and McHugh, PJ and Hartley, JA (2002) PCR-based methods for detecting DNA damage and its repair at the sub-gene and single nucleotide levels in cells. MOL BIOTECHNOL , 20 (2) 181 - 196.

Gupta, N and Saleem, A and Osman, S and Hoskin, P and Price, PM and Aboagye, EO (2002) Carbogen and nicotinamide selectively increase chemotherapy delivery and blood flow to liver metastasis. British Journal of Cancer , 86 S14 - S14.

H

Harney, J and Goodchild, K and Glynne-Jones, R and Phillips, H and Hoskin, PJ and Saunders, MI (2002) A Phase I/II Study of CHARTWEL with concurrent chemotherapy in locally advanced inoperable carcinoma of the oesphagus. In: Radiotherapy And Oncology. (pp. S27 - ?).

Harney, J and Goodchild, K and Glynne-Jones, R and Phillips, H and Hoskin, PJ and Saunders, MI (2002) A phase II study of CHARTWEL with concurrent chemotherapy in locally advanced, inoperable carcinoma of the oesophagus. In: Radiotherapy And Oncology. (pp. 83 - ?).

Harney, J and Shah, N and Joiner, M and Short, S and Saunders, MI (2002) Low dose hyper-sensitivity- does it occur in normal skin? In: Proc 21st Annual ESTRO meeting, Prague 2002.

Harney, J and Shah, N and Short, SC and Joiner, M and Saunders, MI (2002) Low dose hyper-radiosensitivity - does it exist in normal skin? In: Radiotherapy And Oncology. (pp. S57 - ?).

Harney, J and Short, SC and Saunders, MI (2002) Low dose hyper-radiosensitivity - A clinical assessment. In: British Journal of Cancer. (pp. S56 - ?).

Hartley, JA and Spanswick, VJ and Pedley, RB and Hollingshead, MG and Alley, MC and Schultz, R and Gregson, SJ and Howard, PW and Thurston, DE (2002) In vitro antitumor activity and in vivo DNA interstrand crosslinking by the novel pyrrolobenzodiazepine dimer SJG-136 (NSC 694501). In: Proceedings of the American Association of Cancer Research. (pp. 2432 - ?).

Hartley, JA and Spanswick, VJ and Pedley, RB and Hollingshead, MG and Alley, MC and Schultz, R and Gregson, SJ and Howard, PWAT and D, E (2002) In vitro activity and in vivo DNA interstrand crosslinking by the novel pyrrolobenzodiazepine dimer SJG-136 (NSC 694501). In: (Proceedings) Proceedings American Association for Cancer Research. (pp. 489 - ?).

Hoskin, P (2002) Secondary malignancies after radiotherapy. The Lancet Oncology , 3 (9) 577 - 578.

Hoskin, PJ (2002) Conformal radiotherapy to the prostate: are bigger fields better? Clinical Oncology , 14 (4) 296 - 297.

Hoskin, PJ (2002) FDG PET in the management of lymphoma: a clinical perspective. European Journal of Nuclear Medicine and Molecular Imaging , 29 (4) 449 - 451.

Hoskin, PJ (2002) Tumour hypoxia and vascularity in lymphoma. In: Annals Of Oncology. (pp. 615 - ?).

Hoskin, PJ (2002) Radiotherapy in cancer pain management. In: Rice, ASC and Warfield, CA and Justins, D and Eccleston, C and Arnold, E, (eds.) Clinical Pain Management. (253 - 258). : London.

Hoskin, PJ (2002) Radiotherapy in palliative care. In: Rice, ASC and Warfield, CA and Justins, D and Eccleston, C and Arnold, E, (eds.) Clinical Pain Management. (281 - 292). Arnold: London.

Hoskin, PJ and Bownes, P and Summers, A (2002) The influence of applicator angle on dosimetry in vaginal vault brachytherapy. British Journal of Radiology , 75 (891) 234 - 237.

Hoskin, PJ and Grover, A and Bhana, R (2002) Optimal radiotherapy dose for metastatic spinal canal compression. British Journal of Cancer , 86 S20 - S20.

Hoskin, PJ and Morgan, DAL and Robinson, M (2002) Erythropoetin supplementation for radical radiotherapy in head and neck cancer: an interim analysis of a randomized phase III trial. In: Radiotherapy And Oncology. (pp. 83 - ?).

Howard, TT and Lingerfelt, BM and Purnell, BL and Scott, AE and Price, CA and Townes, HM and McNulty, L and Handl, HL and Summerville, K and Hudson, SJ and Bowen, JP and Kiakos, K and Hartley, JA and Lee, M (2002) Novel furano analogues of duocarmycin C1 and C2: Design, synthesis, and biological evaluation of seco-iso- cyclopropylfurano[2,3-e]indoline (seco-iso-CFI) and seco- cyclopropyltetrahydrofurano[2,3-f]quinoline (seco-CFQ) analogues. Bioorganic and Medicinal Chemistry , 10 (9) 2941 - 2952.

Howard, TT and Lingerfelt, BM and Purnell, BL and Scott, AE and Price, CA and Townes, HM and McNulty, L and Handl, HL and Summerville, K and Hudson, SJ and Bowen, JP and Kiakos, K and Hartley, JA and Lee, M (2002) Novel furano analogues of duocarmycin C1 and C2: Design, synthesis, and biological evaluation of seco-iso-cyclopropylfurano[2,3-e]indoline (seco-iso-CFI) and seco-cyclopropyltetrahydrofurano[2,3-f]quinoline (seco-CFQ) analogues. BIOORGAN MED CHEM , 10 (9) 2941 - 2952.

Hughes, A and Calvert, P and Azzabi, A and Plummer, R and Johnson, R and Rusthoven, J and Griffin, M and Fishwick, K and Boddy, AV and Verrill, M and Calvert, H (2002) Phase I clinical and pharmacokinetic study of pemetrexed and carboplatin in patients with malignant pleural mesothelioma. J CLIN ONCOL , 20 (16) 3533 - 3544. 10.1200/JCO.2002.10.073.

J

Janinis, J and McTiernan, A and Driver, D and Mitchell, C and Cassoni, AM and Pringle, J and Kilby, A and Whelan, JS and London Bone and Soft Tissue Tumour, (2002) A pilot study of short-course intensive multiagent chemotherapy in metastatic and axial skeletal osteosarcoma. ANN ONCOL , 13 (12) 1935 - 1944. 10.1093/annonc/mdf338.

Jones, B and Aird, E and Colyer, H and Dobbs, J and Harris, R and Hoskin, P and McKenzie, A and West, C (2002) United Kingdom Radiation Oncology 1 conference (UKRO 1): Accuracy and uncertainty in radiotherapy. British Journal of Radiology , 75 (892) 297 - 306.

Judson, I and Leahy, M and Whelan, JS and Lorigan, P and Verrill, M and Grimer, R and Robinson, M (2002) A guideline for the management of gastrointestinal stromal tumour (GIST). Sarcoma , 6 83 - 87.
An open access publication

K

Kiakos, K and Howard, TT and Lee, M and Hartley, JA and McHugh, PJ (2002) Saccharomyces cerevisiae RAD5 influences the excision repair of DNA minor groove adducts. J BIOL CHEM , 277 (46) 44576 - 44581. 10.1074/jbc.M208169200.
An open access publication

Kirkby, N and Faraday, DBF and Short, S and C, W and M, J and M C, B and N, G (2002) Mathematical modelling to develop a novel radiotherapy schedule for high grade brain tumours, based on phase distribution of low-dose hypersensitivity in human glioma cell lines. In: Proc 21st Annual ESTRO meeting, Prague 2002.

Koch, SSC and Thoresen, LH and Tikhe, JG and Maegley, KA and Almassy, RJ and Li, JK and Yu, XH and Zook, SE and Kumpf, RA and Zhang, C and Boritzki, TJ and Mansour, RN and Zhang, KE and Ekker, A and Calabrese, CR and Curtin, NJ and Kyle, S and Thomas, HD and Wang, LZ and Calvert, AH and Golding, BT and Griffin, RJ and Newell, DR and Webber, SE and Hostomsky, Z (2002) Novel tricyclic poly(ADP-ribose) polymerase-1 inhibitors with potent anticancer chemopotentiating activity: Design, synthesis, and X-ray cocrystal structure. J MED CHEM , 45 (23) 4961 - 4974. 10.1021/jm02059n.

Kularatne, BY and Lorigan, P and Browne, S and Suvarna, SK and Smith, NO and Lawry, J (2002) Monitoring tumour cells in the peripheral blood of small cell lung cancer patients. CYTOMETRY , 50 (3) 160 - 167. 10.1002/cyto.10071.

L

Lee, SM and James, LE and Mohamed-Ali, V and Boschoff, C and Snee, M and Brock, C and Leary, A and Ball, L and Prendiville, J (2002) A phase II study of carboplatin/etoposide with thalidomide in small cell lung cancer (SCLC). In: (Proceedings) Oral presentation. 2002 ASCO Annual Meeting/38th Annual Meeting, Orlando, FL.. (pp. 1251 - ?). Proceedings of the American Society of Clinical Oncology

Lee, YC and Boehm, MK and Chester, KA and Begent, RHJ and Perkins, SJ (2002) Reversible dimer formation and stability of the anti-tumour single-chain Fv antibody MFE-23 by neutron scattering, analytical ultracentrifugation, and NMR and FT-IR spectroscopy. J MOL BIOL , 320 (1) 107 - 127. 10.1016/S0022-2836(02)00403-5.

Leonard, P and Seymour, MT and James, R and Hochhauser, D and Ledermann, JA (2002) Phase II study of irinotecan with bolus and high dose infusional 5-FU and folinic acid (modified de Gramont) for first or second line treatment of advanced or metastatic colorectal cancer. BRIT J CANCER , 87 (11) 1216 - 1220. 10.1038/sj.bjc.6606641.

M

Madsen, E and Summerville, K and Price, C and Toth, J and Hudson, S and Kiakos, K and Hartley, J and Lee, M (2002) Molecular recognition of DNA sequence-specific alkylation by conjugates of hairpin polyamide-duocarmycin analogs. ABSTR PAP AM CHEM S , 223 A106 - A106.

Makris, A and Burcombe, RJ and Wilson, GD and Richman, PI and Allen, S and Wright, D and Pittam, M (2002) Comparison of clinical, radiological and pathological assessment of response to neoadjuvant chemotherapy for primary breast cancer. European Journal of Cancer , 38 268 - ?.

Mayer, A and Spencer, DIR and Tolner, B and Purdy, D and Begent, RHJ and Chester, K (2002) A recombinant fusion protein with potentially reduced immunogenicity for ADEPT. British Journal of Cancer , 86 S117 - S117.

Mayer, A and Spencer, DIR and Tolner, B and Purdy, D and Begent, RHJ and Chester, K (2002) A recombinant fusion protein with potentially reduced immunogenicity for ADEPT. BRIT J CANCER , 86 S117 - S117.

McHugh, PJ and Kiakos, K and Hartley, JA and Lee, M (2002) The Rad6 pathway is involved in the nucleotide excision repair of DNA minor groove adducts. In: Proceedings of the American Association of Cancer Research. (pp. 5103 - ?).

N

Nehls, O and Klump, B and Arkenau, HT and Hass, HG and Greschniok, A and Gregor, M and Porschen, R (2002) Oxaliplatin, fluorouracil and leucovorin for advanced biliary system adenocarcinomas: a prospective phase II trial. Br J Cancer , 87 (7) 702 - 704. 10.1038/sj.bjc.6600543.

Nicholson, PW and Harland, SJ (2002) Survival prospects after screen-detection of prostate cancer. BJU INT , 90 (7) 686 - 693. 10.1046/j.1464-4096.2002.03005.x.

Niyikiza, C and Baker, SD and Seitz, DE and Walling, JM and Nelson, K and Rusthoven, JJ and Stabler, SP and Paoletti, P and Calvert, AH and Allen, RH (2002) Homocysteine and methylmalonic acid: Markers to predict and avoid toxicity from pemetrexed therapy. MOL CANCER THER , 1 (7) 545 - 552.

Niyikiza, C and Hanauske, AR and Rusthoven, JJ and Calvert, AH and Allen, R and Paoletti, P and Bunn, PA (2002) Pemetrexed safety and dosing strategy. SEMIN ONCOL , 29 (6) 24 - 29. 10.1053/sonc.2002.37465.

O

O'Hare, CC and Mack, D and Tandon, M and Sharma, SK and Lown, JW and Kopka, ML and Dickerson, RE and Hartley, JA (2002) DNA sequence recognition in the minor groove by crosslinked polyamides: The effect of N-terminal head group and linker length on binding affinity and specificity. P NATL ACAD SCI USA , 99 (1) 72 - 77.

P

Parmar, MKB and Adams, M and Balestrino, M and Bertelsen, K and Bonazzi, C and Calvert, H and Colombo, N and Delaloye, JF and Durando, A and Guthrie, D and Hagen, B and Harper, P and Mangioni, C and Perren, T and Poole, C and Qian, W and Rustin, G and Sandercock, J and Tumolo, S and Torri, V and Vecchione, F and ICON Grp, (2002) Paclitaxel plus carboplatin versus standard chemotherapy with either single-agent carboplatin or cyclophosphamide, doxorubicin, and cisplatin in women with ovarian cancer: the ICON3 randomised trial. LANCET , 360 (9332) 505 - 515.

Paul, MJ and Summers, Y and Calvert, AH and Rustin, G and Brampton, MH and Thatcher, N and Middleton, MR (2002) Effect of temozolomide on central nervous system relapse in patients with advanced melanoma. MELANOMA RES , 12 (2) 175 - 178.

Pedley, RB and El-Emir, E and Flynn, AA and Boxer, GM and Dearling, J and Raleigh, JA and Hill, SA and Stuart, S and Motha, R and Begent, RHJ (2002) Synergy between vascular targeting agents and antibody-directed therapy. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS , 54 (5) 1524 - 1531.

Pedley, RB and Sharma, SK and Chester, KA (2002) Antibody-directed Enzyme Prodrug Therapy. In: Suicide Gene Therapy: Methods and Protocols for Cancer. Humana Press

Peters, GJ and Backus, HHJ and Freemantle, S and van Triest, B and Codacci-Pisanelli, G and van der Wilt, CL and Smid, K and Lunec, J and Calvert, AH and Marsh, S and McLeod, HL and Bloemena, E and Meijer, S and Jansen, G and van Groeningen, CJ and Pinedo, HM (2002) Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE , 1587 (2-3) 194 - 205.

Petrie, IA and Flynn, AA and Pedley, RB and Green, AJ and El Emir, E and Dearling, JLJ and Boxer, GM and Boden, R and Begent, RHJ (2002) Spatial accuracy of 3D reconstructed radioluminographs of serial tissue sections and resultant absorbed dose estimates. Physics in Medicine and Biology , 47 (20) 3651 - 3661.

Petrie, IA and Flynn, AA and Pedley, RB and Green, AJ and El-Emir, E and Dearling, J and Boxer, GM and Boden, RABRHJ (2002) The spatial accuracy of 3D reconstructed radioluminographs on serial tissue sections and the resultant absorbed dose estimates. Physics in Medicine and Biology , 47 3651 - 3661.

Petrie, IA and Flynn, AA and Pedley, RB and Green, AJ and El-Emir, E and Dearling, JLJ and Boxer, GM and Boden, R and Begent, RHJ (2002) Spatial accuracy of 3D reconstructed radioluminographs of serial tissue sections and resultant absorbed dose estimates. PHYS MED BIOL , 47 (20) 3651 - 3661.

Plummer, R and Ghielmini, M and Calvert, P and Voi, M and Renard, J and Gallant, G and Gupta, E and Calvert, H and Sessa, C (2002) Phase I and pharmacokinetic study of the new taxane analog BMS-184476 given weekly in patients with advanced malignancies. CLIN CANCER RES , 8 (9) 2788 - 2797.

Purnell, B and Howard, T and Lingerfelt, B and McNulty, L and Handl, H and Summerville, K and Hudson, S and Kiakos, K and Hartley, J and Lee, M and Bowen, P (2002) Novel seco-iso-CFI and seco-CFQ analogs of the duocarmycins: Design, synthesis and biological evaluation. ABSTR PAP AM CHEM S , 223 B133 - B133.

Purnell, B and Lingerfelt, B and Scott, A and Summerville, K and Hudson, S and Kiakos, K and Hartley, J and Lee, M (2002) Novel (S)-(+)- and (R)-(-)-seco-iso-CFI analogs of duocarmycin C2. ABSTR PAP AM CHEM S , 223 B133 - B133.

R

Rojas, A and Saunders, MI (2002) Addition of chemotherapy to altered fractionation schedules in non-small cell lung cancer. In: Kogelnik, HD and Lukas, P and Sedlmayer, F, (eds.) Progress in Radio-oncology VII. (437 - 445). Monduzzi

Rojas, A and Saunders, MI (2002) ARCON in clinical radiotherapy. In: Kogelnik, HD and Lukas, P and Sedlmayer, F, (eds.) Progress in Radio-oncology. (89 - 98).

Rudd, RM and Gower, NH and James, LE and Gregory, W and Eisen, T and Lee, SM and et, A (2002) A phase III randomised comparison of gemcitabine/carboplatin with mitomycin/ifosfamide/cisplatin in advanced non-small cell lung cancer. In: (Proceedings) Oral presentation. 2002 Annual ASCO Meeting/38th Annual Meeting, Orlando, FL.. (pp. 1164 - ?). Proceedings of the American Society of Clinical Oncology

S

Saunders, MI (2002) Chart and chemotherapy. Clinical Oncology , 14 (4) 331 - 332.

Saunders, MI and Rojas, A and Lyn, BE and Wilson, E and Phillips, H (2002) Dose-escalation with CHARTWEL (Continuous Hyperfractionated Accelerated Radiotherapy Week-End Less) combined with neo- adjuvant chemotherapy in the treatment of locally advanced non- small cell lung cancer. Clinical Oncology , 14 (5) 352 - 360.

Schellens, JHM and Heinrich, B and Lehnert, M and Gore, ME and Kaye, SB and Dombernowsky, P and Paridaens, R and van Oosterom, AT and Verweij, J and Loos, WJ and Calvert, H and Pavlidis, N and Cortes-Funes, H and Wanders, J and Roelvink, M and Sessa, C and Selinger, K and Wissel, PS and Gamucci, T and Hanauske, AR (2002) Population pharmacokinetic and dynamic analysis of the topoisomerase I inhibitor lurtotecan in phase II studies. INVEST NEW DRUG , 20 (1) 83 - 93.

Sharma, SK and Pedley, RB and Bhatia, J and Irwin, HL and El-Emir, E and Boxer, GM and Boden, RW and Chester, KAAB and R, HJ (2002) Antibody-directed enzyme prodrug therapy (ADEPT): comparison in two colorectal carcinoma xenografts. In: (Proceedings) proceedings AmericanAssociation for Cancer Research. (pp. 943 - ?).

Short, SC and Harney, J and Dopson, F and Saunders, MI (2002) The effects of low-dose fractionated radiation on sarcomas- experimental and clinical data. British Journal of Cancer , 86 S56 - S57.

Sibtain, A and Hill, S and Goodchild, K and Shah, N and Saunders, M and Hoskin, PJ (2002) The modification of human tumour blood flow using pentoxifylline, nicotinamide and carbogen. Radiotherapy And Oncology , 62 (1) 69 - 76.

Sibtain, A and Wilson, GD and Hoskin, PJ (2002) Hypoxia in bladder cancer: Validation of intrinsic markers with pimonidazole and their influence on clinical outcome after accelerated radiotherapy with carbogen and nicotinamide. British Journal of Cancer , 86 S28 - S29.

Sierens, J and Hartley, JA and Campbell, MJ and Leathem, AJC and Woodside, JV (2002) In vitro isoflavone supplementation reduces hydrogen peroxide-induced DNA damage in sperm. TERATOGEN CARCIN MUT , 22 (3) 227 - 234. 10.1002/tcm.10015.

Simpson, AB and Calvert, PM and Sludden, JA and Boddy, AV and Griffin, MJ and Schatzlein, A and Wilson, P and Fishwick, K and Wheatley, A and Ross, GA and Calvert, AH and Twelves, CJ (2002) Topotecan in combination with carboplatin: phase I trial evaluation of two treatment schedules. ANN ONCOL , 13 (3) 399 - 402. 10.1093/annonc/mdf041.

Southworth, R and Dearling, J and Medina, R and Flynn, A and Pedley, RBAG and P, (2002) 18FDG and 14C DG6P accumulation differ in the isolated heart: an autoradiographic study. In: J Mol. Cell. Cardiol. (pp. 59 - ?).

Southworth, R and Dearling, JLJ and Medina, RA and Flynn, AA and Pedley, RB and Garlick, PB (2002) Dissociation of glucose tracer uptake and glucose transporter distribution in the regionally ischaemic isolated rat heart: application of a new autoradiographic technique. EUR J NUCL MED MOL I , 29 (10) 1334 - 1341. 10.1007/s00259-002-0922-2.

Spalding, DRC and Hochhauser, D and Hartley, J and Davidson, B (2002) Heterogeneity of response to chemotherapy in liver tumours evaluated by the comet assay in an isolated perfused human liver. British Journal Of Surgery , 89 50 - 50.

Spanswick, VJ and Craddock, C and Sekhar, M and Mahendra, P and Shankaranarayana, P and Hughes, RG and Hochhauser, D and Hartley, JA (2002) Repair of DNA interstrand crosslinks as a mechanism of clinical resistance to melphalan in multiple myeloma. BLOOD , 100 (1) 224 - 229.
An open access version is available from UCL Discovery

Spencer, DI and Robson, L and Purdy, D and Whitelegg, NR and Michael, NP and Bhatia, J and Sharma, SK and Rees, AR and Minton, NP and Begent, RH and Chester, KA (2002) A strategy for mapping and neutralizing conformational immunogenic sites on protein therapeutics. Proteomics , 2 (3) 271 - 279.

Spencer, DIR and Robson, L and Purdy, D and Whitelegg, NR and Michael, NP and Bhatia, J and Sharma, SK and Rees, AR and Minton, NP and Begent, RHJ and Chester, KA (2002) A strategy for mapping and neutralizing conformational immunogenic sites on protein therapeutics. PROTEOMICS , 2 (3) 271 - 279.

Szekely, Z and Kosakowska-Cholody, T and Hartley, JA and Michejda, CJ (2002) Coupling minor groove binders with intercalators, an attempt to design chemical gene knockout agents. In: Proceedings of the American Association of Cancer Research. (pp. 2428 - ?).

T

Tchilian, EZ and Dawes, R and Ramaley, PA and Whitworth, JA and Yuldasheva, N and Wells, RS and Watera, C and French, N and Gilks, CF and Kunachiwa, W and Ruzibakiev, R and Leetrakool, N and Carrington, CVF and Ramdath, DD and Gotch, F and Stephens, HA and Hill, AV and Beverley, PCL (2002) A CD45 polymorphism associated with abnormal splicing is absent in African populations. IMMUNOGENETICS , 53 (10-11) 980 - 983. 10.1007/s00251-001-0410-z.

Thomas, HD and Porter, DJ and Bartelink, I and Nobbs, JR and Cole, M and Elliott, S and Newell, DR and Calvert, AH and Highley, M and Boddy, AV (2002) Randomized cross-over clinical trial to study potential pharmacokinetic interactions between cisplatin or carboplatin and etoposide. BRIT J CLIN PHARMACO , 53 (1) 83 - 91.

Thomas, R and Makris, A and Bloomfield, D and Godward, S and Moody, M (2002) Empowering patients to make informed treatment decisions based on tolerability, quality of life patient preference. A comparison of letrozole and anastrazole in a multicentre, randomised, single-blind cross over study. European Journal of Cancer , 38 171 - ?.

Toth, JL and Price, CA and Madsen, EC and Handl, HL and Hudson, SJ and Hubbard, RB and Bowen, JP and Kiakos, K and Hartley, JA and Lee, M (2002) Sequence selective recognition of DNA by hairpin conjugates of a racemic seco-cyclopropaneindoline-2-benzofurancarboxamide and polyamides. BIOORG MED CHEM LETT , 12 (16) 2245 - 2248.

Trent, S and Kong, A and Short, SC and Traish, D and Ashley, S and Dowe, A and Hines, F and Brada, M (2002) Temozolomide as second-line chemotherapy for relapsed gliomas. Journal of Neuro-Oncology , 57 (3) 247 - 251.

U

UCL, 22AR (2002) Achievements: UCL's academics conducted pioneering work at the forefront of their disciplines during this year. 12 - 13.

UCL, PS (2002) Thalidomide to be used in cancer fight. 44 - ?.

V

Vassileva, V and Millar, A and Briollais, L and Chapman, W and Bapat, B (2002) Genes involved in DNA repair are mutational targets in endometrial cancers with microsatellite instability. CANCER RES , 62 (14) 4095 - 4099.

Venables, K and Winfield, E and Aird, E and Hoskin, PJ (2002) Three-dimensional distribution of radiation within the breast: an intercomparison of departments participating in the START trial of breast radiotherapy fractionation. International Journal of Radiation Oncology Biology Physics , 55 271 - 279.

W

Whelan, JS and Burcombe, RJ and Janinis, J and Baldelli, AM and Cassoni, AM (2002) A systematic review of the role of pulmonary irradiation in the management of primary bone tumours. Ann Oncol , 13 (1) 23 - 30.

Winfield, E and Deighton, A and Venables, K and Hoskin, PJ and Aird, EGA (2002) Survey of UK breast radiotherapy techniques: Background prior to the introduction of the quality assurance programme for the START (Standardisation of Radiotherapy) Trial in breast cancer. Clinical Oncology , 14 (4) 267 - 271.

Wong, WL and Campbell, H and Saunders, M (2002) Positron emission tomography (PET) - Evaluation of 'indeterminate pulmonary lesions'. Clinical Oncology , 14 (2) 123 - 128.

Z

Zehnder, D and Bland, R and Chana, RS and Wheeler, DC and Howie, AJ and Williams, MC and Stewart, PM and Hewison, M (2002) Synthesis of 1,25-dihydroxyvitamin D-3 by human endothelial cells is regulated by inflammatory cytokines: A novel autocrine determinant of vascular cell adhesion. J AM SOC NEPHROL , 13 (3) ? - ?.

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