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Number of items: 66.


Al-Alwan, MM; Okkenhaug, K; Vanhaesebroeck, B; Hayflick, JS; Marshall, AJ; (2007) Requirement for phosphoinositide 3-kinase p110delta signaling in B cell antigen receptor-mediated antigen presentation. J Immunol , 178 (4) 2328 - 2335.

Alonzi, R; Padhani, AR; Taylor, NJ; Stirling, JJ; Saunders, MI; Hoskin, PJ; (2007) Physiological changes within the prostate caused by androgen withdrawal. In: CLINICAL ONCOLOGY. (pp. S6 - S6).


Bajwa, A; Blunt, N; Vyas, S; McKenzie, G; Bridgewater, J; Hochhauser, D; Obichere, A; (2007) Predictive factors of outcome in patients with asymptomatic stage IV colorectal cancer and irresectable liver metastases. In: Annals of Oncology. (pp. V1170 - V1170).

Begent, RHJ; Sharma, SK; Mayer, A; Tolner, B; Pedley, RB; Wilkins, D; ... Chester, KA; + view all (2007) Incorporating single chain Fv antibodies into therapeutic proteins: issues exemplified in antibody-directed enzyme prodrug therapy (ADEPT). In: IMMUNOLOGY. (pp. 42 - 42). BLACKWELL PUBLISHING

Beresford, M; Lyburn, I; Sanghera, B; Makris, A; Wong, WL; (2007) Serial integrated F-18-fluorodeoxythymidine PET/CT monitoring neoadjuvant chemotherapeutic response in invasive ductal carcinoma. BLACKWELL PUBLISHING


Chong, IY; Hoskin, PJ; (2007) Vaginal vault brachytherapy for low risk endometrial carcinoma. In: CLINICAL ONCOLOGY. (pp. S8 - S8).

Chong, IY; Rojas, A; Hoskin, PJ; (2007) Does a fall in lymphocyte or neutrophil count during chemoradiotherapy predict survival in cervical carcinoma? In: CLINICAL ONCOLOGY. (pp. S25 - S26).

Cutillas, PR; Vanhaesebroeck, B; (2007) Quantitative profile of five murine core proteomes using label-free functional proteomics. Mol Cell Proteomics , 6 (9) 1560 - 1573. 10.1074/mcp.M700037-MCP200.


Dancey, G; Violet, J; Othman, S; Parker, S; Green, A; Sharma, S; ... McNamara, C; + view all (2007) Phase I trial of the I-131-labelled Anti-CD25 antibody basiliximab in the treatment of patients with relapsed or refractory lymphoma. In: BLOOD. (pp. 199A - 200A). AMER SOC HEMATOLOGY

Dearling, JL; Pedley, RB; (2007) Technological advances in radioimmunotherapy. Clin Oncol (R Coll Radiol) , 19 (6) 457 - 469. 10.1016/j.clon.2007.03.016.

Dearling, JLJAPRB; (2007) Antibody directed radionuclide therapy. In: Hoskin, PJ, (ed.) Radiotherapy in Practice: Volume III Radioisotopes. (9 - 45). Oxford University Press.

Diez, P; Hoskin, PJ; (2007) Conventional and CT-based volumes in IFRT for supradiaphragmatic malignant lymphoma. In: CLINICAL ONCOLOGY. (pp. S16 - S16).


El-Emir, E; Qureshi, U; Dearling, JLJ; Boxer, GM; Clatworthy, I; Folarin, AA; ... Pedley, RB; + view all (2007) Predicting response to radioimmunotherapy from the tumor microenvironment of colorectal carcinomas. Cancer Research , 67 2639 - 2646.


Forster, M; Kaye, S; Oza, A; Sklenar, I; Johri, A; Cheung, W; ... Gore, M; + view all (2007) A phase Ib and pharmacokinetic trial of patupilone combined with carboplatin in patients with advanced cancer. Clin Cancer Res , 13 (14) 4178 - 4184. 10.1158/1078-0432.CCR-06-1653.

Fox, J; Glasspool, D; Grecu, D; Modgil, S; South, M; Patkar, V; (2007) Argumentation-based inference and decision making - A medical perspective. IEEE INTELL SYST , 22 (6) 34 - 41.

Furnari, FB; Fenton, T; Bachoo, RM; Mukasa, A; Stommel, JM; Stegh, A; ... Cavenee, WK; + view all (2007) Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes & Development , 21 (21) 2683 - 2710. 10.1101/gad.1596707.


Geering, B; Cutillas, PR; Nock, G; Gharbi, SI; Vanhaesebroeck, B; (2007) Class IA phosphoinositide 3-kinases are obligate p85-p110 heterodimers. Proc Natl Acad Sci U S A , 104 (19) 7809 - 7814. 10.1073/pnas.0700373104.

Geering, B; Cutillas, PR; Vanhaesebroeck, B; (2007) Regulation of class IA PI3Ks: is there a role for monomeric PI3K subunits? In: Biochem Soc Trans. (pp. 199 - 203).


Hochhauser, D; Kotecha, M; O'Hare, C; Morris, PJ; Hartley, JM; Taherbhai, Z; ... Hartley, JA; + view all (2007) Modulation of topoisomerase II expression in mammalian cells with a sequence-specific polyamide. Molecular Cancer Therapeutics , 6 (1) 346 - 354.

Hoskin, PJ; Bownes, P; Bryant, L; Ostler, P; (2007) HDR monotherapy brachytherapy for localised prostate cancer. In: CLINICAL ONCOLOGY. (pp. S7 - S7).

Hoskin, PJ; Carnell, DM; Taylor, NJ; Smith, RE; Stirling, JJ; Daley, FM; ... Padhani, AP; + view all (2007) Hypoxia in prostate cancer: correlation of BOLD-MRI with pimonidazole immunohistochemistry-initial observations. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY , 68 (4) 1065 - 1071.

Hoskin, PJ; Chin, Y; Wong, W; Rojas, A; (2007) The value of SUV in FDG PET for lymphoma. In: CLINICAL ONCOLOGY. (pp. S32 - S32).

Huddart, RA; O'Doherty, MJ; Padhani, A; Rustin, GJ; Mead, GM; Joffe, JK; ... Stenning, SPNCRITTCSG; + view all (2007) 18fluorodeoxyglucose positron emission tomography in the prediction of relapse in patients with high-risk, clinical stage I nonseminomatous germ cell tumors: preliminary report of MRC Trial TE22--the NCRI Testis Tumour Clinical Study Group. Clinical Oncology , 25 (11) 1310 - 1315.


Ji, H; Rintelen, F; Waltzinger, C; Bertschy Meier, D; Bilancio, A; Pearce, W; ... Rommel, C; + view all (2007) Inactivation of PI3Kgamma and PI3Kdelta distorts T-cell development and causes multiple organ inflammation. Blood , 110 (8) 2940 - 2947. 10.1182/blood-2007-04-086751.

Ji, H; Rintelen, F; Waltzinger, C; BertschyMeier, D; Pearce, W; Hirsch, E; ... Rommel, C; + view all (2007) Inactivation of PI3Kg and PI3Kd distorts T cell development and renders susceptibility to multiple organ inflammation. INFLAMMATION RESEARCH , 56 S444 - S444.

Judith, D; (2007) CT scan plan to combat cancer. Sunday Herald


Kishimoto, H; Ohteki, T; Yajima, N; Kawahara, K; Natsui, M; Kawarasaki, S; ... Suzuki, A; + view all (2007) The Pten/PI3K pathway governs the homeostasis of Valpha14iNKT cells. Blood , 109 (8) 3316 - 3324. 10.1182/blood-2006-07-038059.

Kogelberg, H; Sharma, SK; Qureshi, U; Tolner, B; Lowdell, M; Shabakhti, H; ... Chester, KA; + view all (2007) Clearance mechanism of a mannoseylated antibody enzyme fusion protein used in experimental cancer therapy. In: (Proceedings) NCRI Cancer Conference proceedings. (pp. 65 - ?).

Kogelberg, H; Tolner, B; Thomas, G; Di Cara, D; Ramesh, B; Sodha, S; ... Chester, K; + view all (2007) Generation of a single-chain Fv with binding specificity for the integrin, alpha v beta 6, by rational structure based antibody engineering – a promising agent for cancer therapy. In: (Proceedings) NCRI Cancer Conference Proceedings.

Koukourakis, MI; Bentzen, SM; Giatromanolaki, A; Wilson, GD; Daley, FM; Saunders, MI; ... Harris, AL; + view all (2007) Endogenous markers of two separate hypoxia response pathways (HIF2 alpha and CA9) predict radiotherapy failure in head and neck cancer patients recruited in the CHART randomized trial. Journal of Clinical Oncology , 24 (5) 727 - 735. 10.1200/jco.2005.02.7474.


Ladenstein, R; Whelan, J; Oberlin, O; Weston, C; Jurgens, H; (2007) Multivariate analysis based risk grouping of Ewing tumours (ET) with extra-pulmonary metastatic disease (EPMD): Final results from the Euro Ewing 99 study. In: ASCO Chicago 2007.

Lee, SM; Woll, PJ; James, LJ; Hatton, M; Ali, K; Spiro, SG; ... Hackshaw, A; + view all (2007) A phase III randomised, double blind, placebo controlled trial of etoposide/carboplatin with or without thalidomide in advanced small cell lung cancer (SCLC). In: (Proceedings) Presidential Symposium. 12th World Conference on Lung Cancer, Seoul, Korea.. (pp. S306 - S307). Journal of Thoracic Oncology

Lee, SM; Woll, PJ; Rudd,; RM,; Gower, NH; Ottensmeier, CH; ... Hackshaw, A; + view all (2007) A phase III randomised, double blind, placebo controlled trial of gemcitabine/carboplatin with or without thalidomide in advanced non-small cell lung cancer (NSCLC). In: (Proceedings) Proffered Paper. 12th World Conference on Lung Cancer, Seoul, Korea.. (pp. S359 - ?). Journal of Thoracic Oncology

Lewis, IJ; Nooij, MA; Whelan, J; Sydes, MR; Grimer, R; Hogendoorn, PCW; ... Taminiau, AHM; + view all (2007) Improvement in histologic response but not survival in osteosarcoma patients treated with intensified chemotherapy: A randomized phase III trial of the European Osteosarcoma Intergroup. Journal of the National Cancer Institute , 99 (2) 112 - 128.

Lowe, H; Tolner, B; Kogelberg, H; Begent, R; Robson, L; Taylorson, C; Chester, K; (2007) A novel human enzyme with a bis-chloro-phenol prodrug for Antibody Directed Enzyme Prodrug Therapy (ADEPT). In: (Proceedings) NCRI Cancer Conference Proceedings.

Lucy, M; (2007) Why I didn’t have any qualms about taking thalidomide. The Express 56 - ?.


Mandeville, HC; Ng, Q; Milner, J; Taylor, NJ; Stirling, JJ; Padhani, AR; ... Hoskin, PJ; + view all (2007) CA4P and external beam radiotherapy in prostate cancer with assessment of effect by DCE-MRI. In: CLINICAL ONCOLOGY. (pp. S38 - S38).

Marina, N; S Bielack, MS; M Bernstein, TB-B; S Smeland, AH; Whelan, J; (2007) International collaboration is feasible in trials for rare conditions: the EURAMOS experience. In: ASCO Chicago. (pp. Abstract 2 - ?).

Marsh, D; Vigor, K; Kogelberg, H; Tolner, B; Meyer, T; Begent, R; ... Chester, K; + view all (2007) Antibody targeted magnetic nanoparticles for cancer imaging and therapy. In: (Proceedings) NCRI Cancer Conference Proceedings.

McCloskey, EV; Beneton, M; Charlesworth, D; Kayan, K; deTakats, D; Dey, A; ... Kanis, JA; + view all (2007) Clodronate reduces the incidence of fractures in community-dwelling elderly women unselected for osteoporosis: results of a double-blind, placebo-controlled randomized study. J Bone Miner Res , 22 (1) 135 - 141. 10.1359/jbmr.061008.


Nashed, BF; Zhang, T; Al-Alwan, M; Srinivasan, G; Halayko, AJ; Okkenhaug, K; ... Marshall, AJ; + view all (2007) Role of the phosphoinositide 3-kinase p110delta in generation of type 2 cytokine responses and allergic airway inflammation. Eur J Immunol , 37 (2) 416 - 424. 10.1002/eji.200636401.


O'Hare, CC; Uthe, P; Mackay, H; Blackmon, K; Jones, J; Brown, T; ... Hartley, JA; + view all (2007) Sequence recognition in the minor groove of DNA by covalently linked formamido imidazole-pyrrole-imidazole polyamides: Effect of H-pin linkage and linker length on selectivity and affinity. BIOCHEMISTRY-US , 46 (42) 11661 - 11670. 10.1021/bi701053a.

Okkenhaug, K; Ali, K; Vanhaesebroeck, B; (2007) Antigen receptor signalling: a distinctive role for the p110 delta isoform of Pl3K. TRENDS IN IMMUNOLOGY , 28 (2) 80 - 87. 10.1016/j.it.12.007.

Okkenhaug, K; Ali, K; Vanhaesebroeck, B; (2007) Antigen receptor signalling: a distinctive role for the p110delta isoform of PI3K. Trends in Immunology , 28 (2) 80 - 87. 10.1016/j.it.2006.12.007. Green and gold open access


Papakonstanti, EA; Ridley, AJ; Vanhaesebroeck, B; (2007) The p110delta isoform of PI 3-kinase negatively controls RhoA and PTEN. EMBO J , 26 (13) 3050 - 3061. 10.1038/sj.emboj.7601763.

Pepper, C; Lowe, H; Fegan, C; Thurieau, C; Thurston, DE; Hartley, JA; Delavault, P; (2007) Fludarabine-mediated suppression of the excision repair enzyme ERCC1 contributes to the cytotoxic synergy with the DNA minor groove crosslinking agent SJG-136 (NSC 694501) in chronic lymphocytic leukaemia cells. BRIT J CANCER , 97 (2) 253 - 259. 10.1038/sj.bjc.6603853.

Porschen, R; Arkenau, H-T; Kubicka, S; Greil, R; Seufferlein, T; Freier, W; ... Schmoll, H-J; + view all (2007) In reply [10]. Journal of Clinical Oncology , 25 (31) 5045 - 5046. 10.1200/JCO.2007.13.4841.

Porschen, R; Arkenau, H-T; Kubicka, S; Greil, R; Seufferlein, T; Freier, W; ... Schmoll, H-J; + view all (2007) In reply [8]. Journal of Clinical Oncology , 25 (31) 5042 - 5043. 10.1200/JCO.2007.14.4386.


Ravn, P; Patel, A; Bicknell, R; Begent, RHJ; Pedley,; R, B; ... Meyer, T; + view all (2007) UNSPECIFIED In: (Proceedings) NCRI Cancer Conference Proceedings. (pp. 59 - ?).

Roylance, R; Seddon, BM; Sykes, K; Beresford, A; Daniels, S; Whelan, J; (2007) Experience of the use of trabectedin (ET-743, Yondelis) in twenty one patients with pre-treated advanced sarcoma from a single centre. Clinical Oncology , 19 (8) 572 - 576. 10.1016/j.clon.2007.05.006.


Sainz-Pastor, N; Tolner, B; Robson, L; Parizek, P; Binz, K; Forrer, P; ... Chester, K; + view all (2007) Selection and evaluation of designed ankyrin repeat proteins (DARPins) reactive with carcinoembryonic antigen (CEA). In: (Proceedings) NCRI Cancer Conference Proceedings.

Sexton, J; Mackay, H; Brown, T; Kotecha, M; O'Hare, C; Kluza, J; ... Lee, M; + view all (2007) MEDI 309-Regulation of the topoisomerase II alpha gene using polyamides that binds to the inverted CCAAT box present in the promoter. ABSTR PAP AM CHEM S , 234 ? - ?.

Short, SC; Martindale, C; Bourne, S; Brand, J; Johnston, P; (2007) DNA damage response in gliomas and normal human astrocytes. Neuro-Oncology , 9 (4) 404 - 411.

Short, SC; Martindale, C; Bourne, SM; Brand, G; Woodcock, M; Johnston, P; (2007) Damage signalling after TMZ and radiation in glioma cells and sensitisation by inhibition of repair in G2. In:

Sielaff, A; Cooper, A; Mackay, H; Brown, T; O'Hare, C; Kluza, J; ... Lee, M; + view all (2007) Binding of f-PIP and JH-37 to the inverted CCAAT box-2 of the topoisomerase II promoter. ABSTR PAP AM CHEM S , 233 613 - 613.

Sikic, BI; Wakelee, HA; Von Mehren, M; Lewis, NL; Plummer, ER; Calvert, AH; ... Burris, HA; + view all (2007) A phase 1b study to assess the safety of lexatumumab, a human monoclonal antibody that activates TRAIL-R2, in combination with gemcitabine, pemetrexed, doxorubicin or FOLFIRI. MOL CANCER THER , 6 (12) 3454S - 3455S.

Sky, NRSM; (2007) Thalidomide could get cancer treatment licence. UNSPECIFIED

Strauss, SJ; Higginbottom, K; Jüliger, S; Maharaj, L; Allen, P; Schenkein, D; ... Joel, SP; + view all (2007) The proteasome inhibitor bortezomib acts independently of p53 and induces cell death via apoptosis and mitotic catastrophe in B-cell lymphoma cell lines. Cancer Res , 67 (6) 2783 - 2790. 10.1158/0008-5472.CAN-06-3254.


Whelan, J; Smeland, S; Marina, N; Bernstein, M; Sydes, MR; Butterfass-Bahoul, T; ... Bielack, S; + view all (2007) Successful pan-European and trans-Atlantic collaboration in a randomised controlled trial in osteosarcoma: EURAMOS1 (ISRCTN67613327; a trial conducted as part of ECTEUROCORES). In: ). European Journal of Cancer Supplements 5:408-409, 2007. (Abstract).

Whelan, J; Smeland S, MN; Bernstein M, SM; May E, B-BT; Perisoglou M, CD; Calaminus G, MR; ... Bielack, S; + view all (2007) Successful trans-Atlantic collaboration in a randomised controlled trial in osteosarcoma: EURAMOS1 (ISRCTN67613327; a trial conducted as part of ECT-EUROCORES) – a potential model for collaboration in rare diseases. In: National Cancer Research Institute Cancer Conference, Birmingham.

Whelan, J; Sydes, M; Bielack, S; Smeland, S; Marina, N; May, E; ... Bernstein, M; + view all (2007) Successful trans-Atlantic collaboration in a randomised controlled trial in osteosarcoma: EURAMOS1 (ISRCTN67613327; a trial conducted as part of ECT-EUROCORES) – a potential model for collaboration in rare diseases. In: British Sarcoma Group meeting 2008 conference abstracts http://www.bsgconference.org.uk/abst2008/absp-sydes.pdf:.

Whelan, JLI; Nooij M, SM; Grimer R, HP; Memon M, WS; Uscinska B, VGM; Kirkpatrick A, HE; Craft A, TOBOTMRCBO06AEORTC80931CAEOI; (2007) Intensified chemotherapy improved histological response but not survival in patients with operable osteosarcoma of an extremity: results of a randomised phase III study of the European Osteosarcoma Intergroup (MRC BO06 80931 ISRCTN86294690). Journal of the National Cancer Institute , 99 112 - 128.

Whelan, JS; Fern, L; (2007) Cancer in adolescence: Incidence and policy issues. In: Kelly, D and Gibson, F, (eds.) Cancer in Adolescents and Young People: Care and Policy Issues. Blackwell: Oxford.

Wilkins, D; Mayer, A; Sharma, S; Tolner, B; Springer, C; Hartley, J; ... Begent, R; + view all (2007) Interim Results of a Phase I/II Trial of Antibody Directed Enzyme Prodrug Therapy (ADEPT) in Patients with Gastrointestinal Carcinoma. In: (Proceedings) NCRI Cancer Conference Proceedings.

Wood, K; Saunders, MI; Honess, DJ; Maxwell, RJ; Wilson, J; Paul, RL; ... Blower, PJ; + view all (2007) Evaluation of the effects of blood flow on 64Cu-ATSM distribution in a rodent tumour model. In: Radiotherapy & Oncology. (pp. S35 - S36).

Wylie, JP; Mandall, P; Bottomley, D; Hoskin, PJ; (2007) Multi-institutional UK prostate brachytherapy database. In: CLINICAL ONCOLOGY. (pp. S50 - S51).

This list was generated on Thu Dec 25 06:46:28 2014 GMT.