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Number of items: 124.

A

Ali, K; Camps, M; Pearce, WP; Ji, H; Rückle, T; Kuehn, N; ... Vanhaesebroeck, B; + view all (2008) Isoform-specific functions of phosphoinositide 3-kinases: p110 delta but not p110 gamma promotes optimal allergic responses in vivo. J Immunol , 180 (4) 2538 - 2544.

Arkenau, H; Barrius, J; Olmos, D; Ang, JE; De Bono, J; Judson, I; Kaye, SB; (2008) Prospective validation of a prognostic score to improve patient selection for phase-1 trials. In: ANNALS OF ONCOLOGY. (pp. 145 - 145). OXFORD UNIV PRESS

Arkenau, H-T; Carden, CP; de Bono, JS; (2008) Targeted agents in cancer therapy. Medicine , 36 (1) 33 - 37. 10.1016/j.mpmed.2007.10.007.

Arkenau, H-T; Porschen, R; (2008) The combination of oxaliplatin with either capecitabine or infusional 5-fluorouracil/leucovorin results in comparable outcome in patients with metastatic colorectal cancer. American Journal of Hematology/ Oncology , 7 (1) 35 - 37.

Arkenau, HT; Arnold, D; Cassidy, J; Diaz-Rubio, E; Douillard, JY; Hochster, H; ... Porschen, R; + view all (2008) Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: a pooled analysis of randomized trials. J Clin Oncol , 26 (36) 5910 - 5917. 10.1200/JCO.2008.16.7759.

Arkenau, HT; Graeven, U; Kubicka, S; Grothey, A; Englisch-Fritz, C; Kretzschmar, A; ... AIO Colorectal Study Group,; + view all (2008) Oxaliplatin in combination with 5-fluorouracil/leucovorin or capecitabine in elderly patients with metastatic colorectal cancer. Clin Colorectal Cancer , 7 (1) 60 - 64.

Arkenau, HT; Olmos, D; Ang, JE; Barriuso, J; Karavasilis, V; Ashley, S; ... Kaye, S; + view all (2008) 90-Days mortality rate in patients treated within the context of a phase-I trial: how should we identify patients who should not go on trial? Eur J Cancer , 44 (11) 1536 - 1540. 10.1016/j.ejca.2008.04.017.

Arkenau, HT; Olmos, D; Ang, JE; de Bono, J; Judson, I; Kaye, S; (2008) Clinical outcome and prognostic factors for patients treated within the context of a phase I study: the Royal Marsden Hospital experience. Br J Cancer , 98 (6) 1029 - 1033. 10.1038/sj.bjc.6604218.

AViolet, J; Dearling, JLJ; Green, AJ; Begent, RHJ; Pedley, RB; (2008) Fractionated I-131 anti-CEA radioimmunotherapy: effects on xenograft tumour growth and haematological toxicity in mice. BRIT J CANCER , 99 (4) 632 - 638. 10.1038/sj.bjc.6604511.

Ayaru, L; Stoeber, K; Webster, GJ; Hatfield, ARW; Wollenschlaeger, A; Okoturo, O; ... Pereira, SP; + view all (2008) Diagnosis of pancreaticobiliary malignancy by detection of minichromosome maintenance protein 5 in bile aspirates. BRIT J CANCER , 98 (9) 1548 - 1554. 10.1038/sj.bjc.6604342. Gold open access

B

Barriuso, J; Arkenau, HT; Olmos, D; Ang, J; Brunetto, A; Frentzas, S; ... Kaye, S; + view all (2008) PROSPECTIVE VALIDATION OF A PROGNOSTIC SCORE FOR PATIENTS TREATED IN PHASE-I TRIALS. In: ANNALS OF ONCOLOGY. (pp. 164 - 164).

Ben-Smith, A; Gorak-Stolinska, P; Floyd, S; Weir, RE; Lalor, MK; Mvula, H; ... Dockrell, HM; + view all (2008) Differences between naive and memory T cell phenotype in Malawian and UK adolescents: a role for Cytomegalovirus? BMC Infectious Diseases , 8 , Article 139. 10.1186/1471-2334-8-139. Green and gold open access
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Besana, P; Patkar, V; Glasspool, D; Robertson, D; (2008) Distributed Workflows: The OpenKnowledge Experience. In: Meersman, R and Tari, Z and Herrero, P, (eds.) ON THE MOVE TO MEANINGFUL INTERNET SYSTEMS: OTM 2008 WORKSHOPS. (pp. 965 - 975). SPRINGER-VERLAG BERLIN

Bhatti, M; Yahioglu, G; Milgrom, LR; Garcia-Maya, M; Chester, KA; Deonarain, MP; (2008) Targeted photodynamic therapy with multiply-loaded recombinant antibody fragments. INT J CANCER , 122 (5) 1155 - 1163. 10.1002/ijc.23206.

Bielack, S; Marina, N; Ferrari, S; Helman, LH; Smeland, S; Whelan, JS; Reaman, GH; (2008) Response to Meyers et al, Osteosarcoma: The addition of muramyl tripeptide to chemotherapy improves overall survival- a report from the Children's Oncology Group (letter0. Journal of Clinical Oncology , 4 633 - 638.

Bielack, SS; Marina, N; Ferrari, S; Helman, LJ; Smeland, S; Whelan, JS; Reaman, GH; (2008) Osteosarcoma: The same old drugs or more? J CLIN ONCOL , 26 (18) 3102 - 3103. 10.1200/JCO.2008.17.1108.

Bilanges, B; Torbett, N; Vanhaesebroeck, B; (2008) Killing two kinase families with one stone. Nat Chem Biol , 4 (11) 648 - 649. 10.1038/nchembio1108-648.

Booth, CM; Calvert, AH; Giaccone, G; Lobbezoo, MW; Eisenhauer, EA; Seymour, LK; Task Force Methodology Dev Innovat,; (2008) Design and conduct of phase II studies of targeted anticancer therapy: Recommendations from the task force on methodology for the development of innovative cancer therapies (MDICT). EUR J CANCER , 44 (1) 25 - 29. 10.1016/j.ejca.2007.07.031.

Booth, CM; Calvert, AH; Giaccone, G; Lobbezoo, MW; Seymour, LK; Eisenhauer, EA; Task Force Methodology Dev Innovat,; (2008) Endpoints and other considerations in phase I studies of targeted anticancer therapy: Recommendations from the task force on methodology for the development of innovative Cancer Therapies (MDICT). EUR J CANCER , 44 (1) 19 - 24. 10.1016/j.ejca.2007.07.034.

Bridgewater, J; van Laar, R; Floore, A; Van'T Veer, L; (2008) Gene expression profiling may improve diagnosis in patients with carcinoma of unknown primary. Br J Cancer , 98 (8) 1425 - 1430. 10.1038/sj.bjc.6604315.

Brown, T; Mackay, H; Turlington, M; Sutterfield, A; Smith, T; Sielaff, A; ... Lee, M; + view all (2008) Modifying the N-terminus of polyamides: PyImPyIm has improved sequence specificity over f-ImPyIm. BIOORGAN MED CHEM , 16 (9) 5266 - 5276. 10.1016/j.bmc.2008.03.008.

Brown, T; Mackay, H; Turlington, M; Sutterfield, A; Smith, T; Sielaff, A; ... and Lee, M; + view all (2008) Modifying the N-Terminus of Polyamides: PyImPyIm has Improved Sequence Specificity over f-ImPyIm. Bioorganic and Medicinal Chemistry , 16 5266 - 5276.

Buchler, T; Dubash, S; Lee, V; Chilton, D; Cartledge, J; Isaacson, P; ... Lee, SM; + view all (2008) Rituximab failure in fulminant multicentric HIV/human herpesvirus 8-associated Castleman’s disease with multiorgan failure: report of two cases. AIDS , 22 (13) 1685 - 1687.

C

Calvert, AH; Plummer, R; (2008) The development of phase I cancer trial methodologies: the use of pharmacokinetic and pharmacodynamic end points sets the scene for phase 0 cancer clinical trials. CLIN CANCER RES , 14 (12) 3664 - 3669. 10.1158/1078-0432.CCR-07-4559.

Calvert, H; Plummer, ER; Curtin, NJ; Edmondson, R; Drew, Y; (2008) PARP inhibitors in cancer treatment. In: EJC SUPPLEMENTS. (pp. 80 - 80). PERGAMON-ELSEVIER SCIENCE LTD

Cassoni, A; Ali, U; Cave, J; Edwards, SG; Ramsay, A; Miller, RF; Lee, SM; (2008) Remission After Radiotherapy for a Patient With Chemotherapy-Refractory HIV-Associated Primary Effusion Lymphoma. J CLIN ONCOL , 26 (32) 5297 - 5299. 10.1200/JCO.2008.18.3350.

Cassoni, A; Ali, U; Cave, J; Edwards, SG; Ramsay, A; Miller, RF; Siow, ML; (2008) Remission after radiotherapy for a patient with chemotherapy-refractory HIV-associated primary effusion lymphoma. Journal of Clinical Oncology , 26 (32) 5297 - 5299. 10.1200/JCO.2008.18.3350.

Chen, YC; Chiang, HY; Yang, MH; Chen, PM; Chang, SY; Teng, SC; ... Wu, KJ; + view all (2008) Activation of phosphoinositide 3-kinase by the NBS1 DNA repair protein through a novel activation motif. J Mol Med (Berl) , 86 (4) 401 - 412. 10.1007/s00109-008-0302-x.

Chung, Y-L; Troy, H; Griffiths, JR; Kristeleit, R; Aherne, W; Judson, IR; ... Atadja, P; + view all (2008) Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of a novel histone deacetylase inhibitor, LAQ824, in human colon carcinoma cells and xenografts. Neoplasia , 10 (4) 303 - 313. 10.1593/neo.07834. Gold open access

Clingen, PH; Wu, JYH; Miller, J; Mistry, N; Chin, F; Wynne, P; ... Hartley, JA; + view all (2008) Histone H2AX phosphorylation as a molecular pharmacological marker for DNA interstrand crosslink cancer chemotherapy. BIOCHEM PHARMACOL , 76 (1) 19 - 27. 10.1016/j.bcp.2008.03.025.

D

De Bono, JS; Kristeleit, R; Fong, P; Pacey, S; Karavasilis, V; Shaw, H; ... Scott, JW; + view all (2008) Phase I pharmacokinetic and pharmacodynamic study of LAQ824, a hydroxamate histone deacetylase inhibitor with a heat shock protein-90 inhibitory profile, in patients with advanced solid tumors. Clinical Cancer Research , 14 (20) 6663 - 6673. 10.1158/1078-0432.CCR-08-0376.

de Bruin, EC; Medema, JP; (2008) Apoptosis and non-apoptotic deaths in cancer development and treatment response. Cancer Treat Rev , 34 (8) 737 - 749. 10.1016/j.ctrv.2008.07.001.

de Bruin, EC; van de Velde, CJ; van Krieken, JH; Marijnen, CA; Medema, JP; (2008) Epithelial human leukocyte antigen-DR expression predicts reduced recurrence rates and prolonged survival in rectal cancer patients. Clin Cancer Res , 14 (4) 1073 - 1079. 10.1158/1078-0432.CCR-07-1597.

Drew, Y; Calvert, H; (2008) The Potential of PARP Inhibitors in Genetic Breast and Ovarian Cancers. RECENT ADVANCES IN CLINICAL ONCOLOGY , 1138 136 - 145. 10.1196/annals.1414.020.

F

Fern, L; Campbell, C; Eden, T; Grant, R; lewis, I; McCleod, U; ... J,; + view all (2008) Addressing delayed cancer diagnosis in primary care: Patterns of attendance and symptoms of teenagers and young adults seen in 3 general practices during 1 year. In: National Cancer Research Institute Cancer Conference, 2008, Birmingham.

Fern, L; Davies, S; Eden, T; Feltbower, R; Grant, R; Hawkins, M; ... Whelan, J; + view all (2008) Rates of inclusion of teenagers and young adults in England into National Cancer Research Network clinical trials: Report from the National Cancer Research Institute (NCRI) Teenage and Young Adult Clinical Studies Development Group. BRIT J CANCER , 99 (12) 1967 - 1974. 10.1038/sj.bjc.6604751.

Fidarova, EF; El-Emir, E; Boxer, GM; Qureshi, U; Dearling, JLJ; Robson, MP; ... Pedley, RB; + view all (2008) Microdistribution of targeted, fluorescently labeled anti carcinoembryonic antigen antibody in metastatic colorectal cancer: Implications for radioimmunotherapy. CLIN CANCER RES , 14 (9) 2639 - 2646. 10.1158/1078-0432.CCR-07-2031.

Fidarova, EF; El-Emir, E; Boxer, GM; Qureshi, U; Robson, MP; Dearling, JLJ; ... Pedley, RB; + view all (2008) Microdistribution of targeted, fluorescently-labeled anti-carcinoembryonic antigen antibody in metastatic colorectal cancer: implications for radioimmunotherapy. Clinical Cancer Research , 14 2639 - 2646.

Fox, J; Black, E; Chronakis, I; Dunlop, R; Patkar, V; South, M; Thomson, R; (2008) From guidelines to careflows: modelling and supporting complex clinical processes. Stud Health Technol Inform , 139 44 - 62.

G

Gaya, A; Daley, F; Taylor, NJ; Tozer, G; Qureshi, U; Padhani, A; ... Rustin, G; + view all (2008) Relationship between human tumour angiogenic profile and combretastatin-induced vascular shutdown: an exploratory study. BRIT J CANCER , 99 (2) 321 - 326. 10.1038/sj.bjc.6604426.

Gaya, AM; Violet, J; Dancey, G; Green, M; Stratford, M; Sharma, K; ... Meyer, T; + view all (2008) A phase I/II trial of radioimmunotherapy with 131Iodine labelled A5B7 anti-CEA antibody (131I-A5B7) in combination with Combretastatin-A4-Phosphate (CA4P) in advanced gastrointestinal carcinomas. In: Journal of Clinical Oncology. (pp. 14517 - ?).

Gelderblom, H; Sydes, MR; Morgan, RC; Hogendoorn, PC; Lewis, IJ; Nooij, MA; ... Whelan, J; + view all (2008) Survival after recurrent osteosarcoma: Data from three European Osteosarcoma Intergroup (EOI) randomized controlled. In: JOURNAL OF CLINICAL ONCOLOGY.

Giampieri, S; Sahai, E; (2008) Activation of TGF-beta signalling in breast cancer metastatic cells. In: BREAST CANCER RESEARCH. (pp. S3 - S4). BIOMED CENTRAL LTD

Graham, JS; Plummer, R; McCoy, C; Kowal, K; Wiesinger, H; Detjen, K; ... Cassidy, J; + view all (2008) Open-label, non-randomised, inter-individual dose escalation of ZK 304709 with the evaluation of safety, tolerability, pharmacokinetics, oral bioavailability and orientating efficacy after daily administration in patients with advanced cancer (7 d treatment and 14 d recovery). EUR J CANCER , 44 (15) 2162 - 2168. 10.1016/j.ejca.2008.06.006.

Graupera, M; Guillermet-Guibert, J; Foukas, LC; Phng, LK; Cain, RJ; Salpekar, A; ... Vanhaesebroeck, B; + view all (2008) Angiogenesis selectively requires the p110 alpha isoform of PI3K to control endothelial cell migration. NATURE , 453 (7195) 662 - U9. 10.1038/nature06892.

Green, AJ; Francis, RJ; Baig, S; Begent, RHJ; (2008) Semiautomatic volume of interest drawing for F-18-FDG image analysis - method and preliminary results. EUR J NUCL MED MOL I , 35 (2) 393 - 406. 10.1007/s00259-007-0602-3.

Guillermet-Guibert, J; Bjorklof, K; Salpekar, A; Gonella, C; Ramadani, F; Bilancio, A; ... Vanhaesebroeck, B; + view all (2008) The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma. Proc Natl Acad Sci U S A , 105 (24) 8292 - 8297. 10.1073/pnas.0707761105.

Guo, H; Samarakoon, A; Vanhaesebroeck, B; Malarkannan, S; (2008) The p110 delta of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation. J Exp Med , 205 (10) 2419 - 2435. 10.1084/jem.20072327.

H

Hazrati, A; Ramis-Castelitort, M; Sarkar, S; Barber, LJ; Schofield, CJ; Hartley, JA; McHugh, PJ; (2008) Human SNM1A suppresses the DNA repair defects of yeast pso2 mutants. DNA REPAIR , 7 (2) 230 - 238. 10.1016/j.dnarep.2007.09.013.

Hiwarkar, P; Arkenau, HT; Treleaven, J; Morgan, G; Potter, M; Ethell, M; (2008) The feasibility of using topotecan, vinorelbine, thiotepa and gemcitabine (TVTG) in adult patients with relapsed/refractory acute lymphoblastic leukaemia/lymphoma. LEUKEMIA , 22 (8) 1627 - 1629. 10.1038/leu.2008.31.

Hochhauser, D; Meyer, T; Loadman, P; Spanswick, VJ; Cobb, M; Begent, RH; ... Jodrell, D; + view all (2008) Phase I study of the DNA minor groove binding pyrrolobenzodiazepine dimer (SJG 136) administered every 21 days in patients with advanced solid tumours. In: JOURNAL OF CLINICAL ONCOLOGY.

Howie, AJ; (2008) Handbook of renal biopsy pathology. (2nd ed. ed.). Springer: New York, USA.

Howie, AJ; Agarwal, A; Sebire, NJ; Trompeter, RS; (2008) Glomerular tip changes in childhood minimal change nephropathy. PEDIATR NEPHROL , 23 (8) 1281 - 1286. 10.1007/s00467-008-0823-0.

Howie, AJ; Brewer, DB; Howell, D; Jones, AP; (2008) Physical basis of colors seen in Congo red-stained amyloid in polarized light. LAB INVEST , 88 (3) 232 - 242. 10.1038/labinvest.3700714.

K

Karavasilis, V; Digue, L; Arkenau, T; Eaton, D; Stapleton, S; de Bono, J; ... Kaye, S; + view all (2008) Identification of factors limiting patient recruitment into phase I trials: a study from the Royal Marsden Hospital. Eur J Cancer , 44 (7) 978 - 982. 10.1016/j.ejca.2008.02.040.

Kogelberg, H; Tolner, B; Thomas, GJ; Di Cara, D; Minogue, S; Ramesh, B; ... Chester, K; + view all (2008) Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus. J MOL BIOL , 382 (2) 385 - 401. 10.1016/j.jmb.2008.07.013.

Kotecha, M; Kluza, J; Wells, G; O'Hare, CC; Forni, C; Mantovani, R; ... Hochhauser, D; + view all (2008) Inhibition of DNA binding of the NF-Y transcription factor by the pyrrolobenzodiazepine-polyamide conjugate GWL-78. MOL CANCER THER , 7 (5) 1319 - 1328. 10.1158/1535-7163.MCT-07-0475.

Krishnamoorthy, N; Oriss, TB; Paglia, M; Fei, M; Yarlagadda, M; Vanhaesebroeck, B; ... Ray, P; + view all (2008) Activation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthma. Nat Med , 14 (5) 565 - 573. 10.1038/nm1766.

L

Lee, AJX; East, P; Pepper, S; Nicke, B; Szallasi, Z; Eklund, AC; ... Swanton, C; + view all (2008) Concordance of exon array and real-time PCR assessment of gene expression following cancer cell cytotoxic drug exposure. CELL CYCLE , 7 (24) 3947 - 3948.

Lee, SM; Brada, M; Stenning, S; Thompson, L; (2008) A randomised trial of Procarbazine, CCNU and Vincristine (PCV) vs Temozolomide (5-day or 21-day schedule) for recurrent high grade glioma (MRC BR12, ISRCTN83176944). In: (Proceedings) Presidential Symposium. 33rd ESMO Congress Stockholm, Sweden.

Lee, SM; Buchler, T; Bomanji, J; Ramsay, A; Edwards, SG; (2008) Thymic 18F-fluorodeoxyglucose uptake on positron emission tomography scanning after doxorubicin, bleomycin, vincristin and dacarbazine chemotherapy and highly-active antiretroviral therapy in HIV-associated Hodgkin's disease in an adult. AIDS , 22 (1) 159 - 160. 10.1097/QAD.0b013e3282f178ef.

Lee, SM; Buchler, T; Grant, H; Lai, C; (2008) Bilateral eardrum perforation after long-term treatment with erlotinib. Journal of Clinical Oncology , 26 (15) 2582 - 2584.

Lee, SM; James, L; Buchler, T; Snee, M; Ellis, P; Hackshaw, A; (2008) Phase II trial of thalidomide with chemotherapy and as maintenance therapy for patients with poor prognosis small-cell lung cancer. Lung Cancer , 59 (3) 364 - 368.

Lee, SM; James, L; Buchler, T; Snee, M; Ellis, P; Hackshaw, A; (2008) Phase II trial of thalidomide with chemotherapy and as maintenance therapy for patients with poor prognosis small-cell lung cancer. Lung Cancer , 59 (3) 364 - 368. 10.1016/j.lungcan.2007.08.032.

Lee, SM; Rudd, RM; Woll, PJ; Ottensmeier, CH; James, LE; Gower, NH; ... Hackshaw, A; + view all (2008) Two randomised phase III, double blind, placebo controlled trials of thalidomide in patients with advanced non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). In: (Proceedings) 2008 ASCO Annual Meeting Proceedings, Chicago, IL. (pp. 435s - ?). Journal of Clinical Oncology

M

Mackay, H; Brown, T; Sexton, JS; Kotecha, M; Nguyen, B; Wilson, WD; ... Hartley, JA; + view all (2008) Targeting the inverted CCAAT Box-2 of the topoisomerase II alpha gene: DNA sequence selective recognition by a polyamide-intercalator as a staggered dimer. BIOORGAN MED CHEM , 16 (4) 2093 - 2102. 10.1016/j.bmc.2007.10.059.

Mackay, H; Brown, T; Uthe, PB; Westrate, L; Sielaff, A; Jones, J; ... Lee, M; + view all (2008) Sequence specific and high affinity recognition of 5 '-ACGCGT-3 ' by rationally designed pyrrole-imidazole H-pin polyamides: Thermodynamic and structural studies. BIOORGAN MED CHEM , 16 (20) 9145 - 9153. 10.1016/j.bmc.2008.09.034.

Marina, N; Bielack,; S,; Whelan, JS; Smeland, S; Krailo, M; ... Bernstein, M; + view all (2008) UNSPECIFIED In: (Proceedings) International collaboration is feasible for trials in rare conditions: the EURAMOS experience. Meeting Proceedings - Paediatric and Adolescent Osteosarcoma. Progress from the past, prospects for the future.. : Houston.

McTiernan, A; Morgan, R; Sydes, MR; Uscinska, B; van, GM; Bramwell, V; ... Whelan, JS; + view all (2008) The more it hurts, the better it works? Chemotherapy toxicity as a predictor of outcome from osteosarcoma: a report from the European Osteosarcoma Intergroup. In: CTOS, London Nov 2008.

Meyer, T; Caplin, M; Palmer, D; Valle, JW; Larvin, M; Waters, J; ... Kato, H; + view all (2008) A phase IB/IIA, multicentre, randomised, double-blind placebo controlled study to evaluate the safety and pharmacokinetics of Z-360 in subjects with unresectable advanced pancreatic cancer in combination with gemcitabine. JOURNAL OF CLINICAL ONCOLOGY , 26 (15)

Muller, CI; Schulmann, K; Reinacher-Schick, A; Andre, N; Arnold, D; Tannapfel, A; ... Graeven, U; + view all (2008) Predictive and prognostic value of microsatellite instability in patients with advanced colorectal cancer treated with a fluoropyrimidine and oxaliplatin containing first-line chemotherapy. A report of the AIO Colorectal Study Group. INT J COLORECTAL DIS , 23 (11) 1033 - 1039. 10.1007/s00384-008-0504-2.

O

Olmos, D; Arkenau, H-T; Ang, JE; de Bono, JS; Judson, I; Kaye, SB; (2008) Reply: Clinical outcome and prognostic factors for patients treated within a phase I study: the Royal Marsden Hospital Experience. BRITISH JOURNAL OF CANCER , 99 (8) 1365 - 1365. 10.1038/sj.bjc.6604649.

P

Papakonstanti, EA; Zwaenepoel, O; Bilancio, A; Burns, E; Nock, GE; Houseman, B; ... Vanhaesebroeck, B; + view all (2008) Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages. J Cell Sci , 121 (Pt 24) 4124 - 4133. 10.1242/jcs.032763.

Patkar, V; Fox, J; (2008) Clinical guidelines and care pathways: a case study applying PROforma decision support technology to the breast cancer care pathway. Stud Health Technol Inform , 139 233 - 242.

Patterson, DM; Murugaesu, N; Holden, L; Seckl, MJ; Rustin, GJ; (2008) A review of the close surveillance policy for stage I female germ cell tumors of the ovary and other sites. Int J Gynecol Cancer , 18 (1) 43 - 50. 10.1111/j.1525-1438.2007.00969.x.

Paulussen, M; Craft, A; Lewis, I; Hackshaw, A; Douglas, C; Dunst, J; ... Jurgens, HFTEICESSG; + view all (2008) Results of the EICESS-92 study: two randomised trials of Ewing's sarcoma treatment. Journal of Clinical Oncology , 20 4385 - 4393.

Paulussen, M; Craft, AW; Lewis, I; Hackshaw, A; Douglas, C; Dunst, J; ... Jurgens, H; + view all (2008) Results of the EICESS-92 study: Two randomized trials of Ewing's sarcoma treatment - Cyclophosphamide compared with ifosfamide in standard-risk patients and assessment of benefit of etoposide added to standard treatment in high-risk patients. J CLIN ONCOL , 26 (27) 4385 - 4393. 10.1200/JCO.2008.16.5720.

Pedley, RB; Qureshi U, E-EE; Fidarova E, BG; Robson M, DF; (2008) OXi4503 shows efficacy as a single agent in colorectal liver metastases in nude mice, and potential for enhancing antibody-targeted therapies. In: (Proceedings) NCRI Cancer Conference Proceedings. (pp. 188 - ?).

Philippar, U; Roussos, ET; Oser, M; Yamaguchi, H; Kim, HD; Giampieri, S; ... Gertler, FB; + view all (2008) A Mena Invasion Isoform Potentiates EGF-Induced Carcinoma Cell Invasion and Metastasis. DEV CELL , 15 (6) 813 - 828. 10.1016/j.devcel.2008.09.003.

Pillai, RG; Forster, M; Perumal, M; Mitchell, F; Leyton, J; Aibgirhio, FI; ... Aboagye, EO; + view all (2008) Imaging pharmacodynamics of the alpha-folate receptor-targeted thymidylate synthase inhibitor BGC 945. Cancer Res , 68 (10) 3827 - 3834. 10.1158/0008-5472.CAN-08-0135.

Plummer, R; Jones, C; Middleton, M; Wilson, R; Evans, J; Olsen, A; ... Calvert, H; + view all (2008) Phase I Study of the Poly (ADP-Ribose) Polymerase Inhibitor, AG014699, in Combination with Temozolomide in Patients with Advanced Solid Tumors. CLIN CANCER RES , 14 (23) 7917 - 7923. 10.1158/1078-0432.CCR-08-1223.

Popat, R; Maharaj, L; Oakervee, H; Cavenagh, J; Middleton, B; Rioja, A; ... Joel, S; + view all (2008) THE NOVEL HDAC INHIBITOR UCL67022 HAS POTENT ACTIVITY IN MULTIPLE MYELOMA CELLS AND REMAINS EFFECTIVE IN A BONE MARROW MICRO-ENVIRONMENT MODEL. In: HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. (pp. 115 - 115). FERRATA STORTI FOUNDATION Gold open access

Post, FA; Campbell, LJ; Hamzah, L; Collins, L; Jones, R; Siwani, R; ... Easterbrook, PJ; + view all (2008) Predictors of renal outcome in HIV-associated nephropathy. CLIN INFECT DIS , 46 (8) 1282 - 1289. 10.1086/529385.

Postel-Vinay, S; Arkenau, HT; Olmos, D; Barriuso, J; Ashley, S; Ang, J; ... Kaye, S; + view all (2008) Patient selection criteria for PHASE-I trials in oncology: Low lymphocyte counts are associated with poor survival. In: ANNALS OF ONCOLOGY. (pp. 34 - 35).

Puzanov, I; Lee, W; Berlin, JD; Calcutt, MW; Hachey, DL; Vermeulen, WL; ... Rothenberg, ML; + view all (2008) Final results of phase I and pharmacokinetic trial of SJG-136 administered on a daily x 3 schedule. In: JOURNAL OF CLINICAL ONCOLOGY.

R

Rajkumar, V; Robson, M; Boxer, G; Begent, RHJ; Pedley, RB; (2008) Imatinib mesylate augments the selective targeting to tumour of radiolabeled anti-CEA antibodies from non-tumour tissues in LS174T and SW1222 xenografts. In: (Proceedings) NCRI Cancer Conference proceedings. (pp. 188 - ?).

Rajkumar, V; Robson, M; Boxer, G; Begent, RHJ; Pedley, RB; (2008) Imatinib mesylate delays tumour regrowth after single dose CA-1-P therapy in LS174T but not SW1222 xenografts. In: (Proceedings) NCRI Cancer Conference proceedings. (pp. 188 - ?).

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