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Number of items: 64.

A

Andrady, C; Sharma, SK; Chester, KA; (2011) Antibody-enzyme fusion proteins for cancer therapy. IMMUNOTHERAPY-UK , 3 (2) 193 - 211. 10.2217/IMT.10.90.

Arkenau, H-K; (2011) Capecitabine combined with oxaliplatin (CAPOX) in clinical practice: how significant is peripheral neuropathy? ANNALS OF ONCOLOGY , 22 (1) 239 - U282. 10.1093/annonc/mdq676.

Arkenau, HT; Kefford, R; Long, GV; (2011) Targeting BRAF for patients with melanoma. Br J Cancer , 104 (3) 392 - 398. 10.1038/sj.bjc.6606030.

Arkenau, HT; Nordman, I; Dobbins, T; Ward, R; (2011) Reporting time-to-event endpoints and response rates in 4 decades of randomized controlled trials in advanced colorectal cancer. Cancer , 117 (4) 832 - 840. 10.1002/cncr.25636.

B

Babu, B; Liu, Y; Plaunt, A; Riddering, C; Ogilvie, R; Westrate, L; ... Lee, M; + view all (2011) Design, synthesis and DNA binding properties of orthogonally positioned diamino containing polyamide f-IPI. BIOCHEM BIOPH RES CO , 404 (3) 848 - 852. 10.1016/j.bbrc.2010.12.073.

Babu, B; Ramos, J; Liu, Y; Chavda, S; Tzou, S; Brockway, O; ... Lee, M; + view all (2011) Design, synthesis, and DNA binding selectivity and affinity studies of the tetraamide PhIPI and its diamino analog PhIP*I. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.

Baraniskin, A; Munding, J; Schulmann, K; Meier, D; Porschen, R; Arkenau, HT; ... Reinacher-Schick, A; + view all (2011) Prognostic value of reduced SMAD4 expression in patients with metastatic colorectal cancer under oxaliplatin-containing chemotherapy: a translational study of the AIO colorectal study group. Clin Colorectal Cancer , 10 (1) 24 - 29. 10.3816/CCC.2011.n.003.

Beltran, L; Chaussade, C; Vanhaesebroeck, B; Cutillas, PR; (2011) Calpain interacts with class IA phosphoinositide 3-kinases regulating their stability and signaling activity. Proc Natl Acad Sci U S A , 108 (39) 16217 - 16222. 10.1073/pnas.1107692108.

Birkbak, NJ; Eklund, AC; Li, Q; McClelland, SE; Endesfelder, D; Tan, P; ... Swanton, C; + view all (2011) Paradoxical relationship between chromosomal instability and survival outcome in cancer. Cancer Res , 71 (10) 3447 - 3452. 10.1158/0008-5472.CAN-10-3667.

Brough, R; Frankum, JR; Sims, D; Mackay, A; Mendes-Pereira, AM; Bajrami, I; ... Ashworth, A; + view all (2011) Functional viability profiles of breast cancer. Cancer Discov , 1 (3) 260 - 273. 10.1158/2159-8290.CD-11-0107.

Brunetto, A; Olmos, D; Arkenau, HT; Tan, D; Yap, T; de Bono, J; ... Kaye, S; + view all (2011) Perceptions and referral trends into phase I oncology trials: results of a clinical survey. J Oncol , 2011 861401 - ?. 10.1155/2011/861401.

C

Calvert, AH; (2011) Synthetic lethality in cancer treatment: Current status of PARP inhibitors. In: ANNALS OF ONCOLOGY. (pp. 13 - 13). OXFORD UNIV PRESS

Cerone, MA; Burgess, DJ; Naceur-Lombardelli, C; Lord, CJ; Ashworth, A; (2011) High-throughput RNAi screening reveals novel regulators of telomerase. Cancer Res , 71 (9) 3328 - 3340. 10.1158/0008-5472.CAN-10-2734.

Chavda, S; Liu, Y; Babu, B; Davis, R; Sielaff, A; Ruprich, J; ... Lee, M; + view all (2011) Hx, a novel fluorescent, minor groove and sequence specific recognition element: Design, synthesis, and DNA binding properties of p-anisylbenzimidazole imidazole/pyrrole-containing polyamides. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.

Chavda, S; Liu, Y; Babu, B; Davis, R; Sielaff, A; Ruprich, J; ... Lee, M; + view all (2011) Hx, a Novel Fluorescent, Minor Groove and Sequence Specific Recognition Element: Design, Synthesis, and DNA Binding Properties of p-Anisylbenzimidazole-imidazole/pyrrole-Containing Polyamides. BIOCHEMISTRY-US , 50 (15) 3127 - 3136. 10.1021/bi102028a.

Chew, SK; Rad, R; Futreal, PA; Bradley, A; Liu, P; (2011) Genetic screens using the piggyBac transposon. Methods , 53 (4) 366 - 371. 10.1016/j.ymeth.2010.12.022.

Cox, ST; Stephens, HAF; Fernando, R; Karasu, A; Harber, M; Howie, AJ; ... Little, A-M; + view all (2011) Major histocompatibility complex class I-related chain A allele mismatching, antibodies, and rejection in renal transplantation. HUMAN IMMUNOLOGY , 72 (10) 827 - 834. 10.1016/j.humimm.2011.05.004.

E

Ertemi, H; Mumtaz, FH; Howie, AJ; Mikhailidis, DP; Thompson, CS; (2011) Effect of Angiotensin II and its Receptor Antagonists on Human Corpus Cavernous Contractility and Oxidative Stress: Modulation of Nitric Oxide Mediated Relaxation. J UROLOGY , 185 (6) 2414 - 2420. 10.1016/j.juro.2011.02.2645.

F

Forster, MD; Dedes, KJ; Sandhu, S; Frentzas, S; Kristeleit, R; Ashworth, A; ... Molife, LR; + view all (2011) Treatment with olaparib in a patient with PTEN-deficient endometrioid endometrial cancer. Nat Rev Clin Oncol , 8 (5) 302 - 306. 10.1038/nrclinonc.2011.42.

Furstenberg, A; Walsh, SB; Howie, A; Jones, G; Unwin, RJ; (2011) Calcineurin-Inhibitor Induced Hypertension, Hyperkalaemia and Metabolic Acidosis Is Caused by Overactivity of the Sodium Chloride Cotransporter. In: AMERICAN JOURNAL OF TRANSPLANTATION. (pp. 406 - 406). WILEY-BLACKWELL

Furuse, J; Okusaka, T; Bridgewater, J; Taketsuna, M; Wasan, H; Koshiji, M; Valle, J; (2011) Lessons from the comparison of two randomized clinical trials using gemcitabine and cisplatin for advanced biliary tract cancer. Crit Rev Oncol Hematol , 80 (1) 31 - 39. 10.1016/j.critrevonc.2010.10.009.

G

Gerlach, B; Cordier, SM; Schmukle, AC; Emmerich, CH; Rieser, E; Haas, TL; ... Walczak, H; + view all (2011) Linear ubiquitination prevents inflammation and regulates immune signalling. Nature , 471 591 - 596. 10.1038/nature09816.

Goldstein, R; Meyer, T; (2011) Role of everolimus in pancreatic neuroendocrine tumors. Expert Rev Anticancer Ther , 11 (11) 1653 - 1665. 10.1586/era.11.145.

Grimmett, C; Bridgewater, J; Steptoe, A; Wardle, J; (2011) Lifestyle and quality of life in colorectal cancer survivors. QUAL LIFE RES , 20 (8) 1237 - 1245. 10.1007/s11136-011-9855-1.

H

Hartley, JM; Spanswick, VJ; Hartley, JA; (2011) Measurement of DNA damage in individual cells using the Single Cell Gel Electrophoresis (Comet) assay. Methods Mol Biol , 731 309 - 320. 10.1007/978-1-61779-080-5_25.

Hochdörfer, T; Kuhny, M; Zorn, CN; Hendriks, RW; Vanhaesebroeck, B; Bohnacker, T; ... Huber, M; + view all (2011) Activation of the PI3K pathway increases TLR-induced TNF-α and IL-6 but reduces IL-1β production in mast cells. Cell Signal , 23 (5) 866 - 875. 10.1016/j.cellsig.2011.01.012.

Holme, H; Nanduri, V; (2011) Superior vena cava obstruction: dangers of a missed diagnosis. J Paediatr Child Health , 47 (3) 150 - 151. 10.1111/j.1440-1754.2010.01741.x.

Howie, AJ; (2011) Problems with 'focal segmental glomerulosclerosis'. Pediatr Nephrol , 26 (8) 1197 - 1205. 10.1007/s00467-010-1701-0.

J

Johansson, AM; Karlsson, MO; Standing, JF; Hill, N; Perisoglou, M; Whelan, J; (2011) A population pharmacokinetic/pharmacodynamic model of methotrexate and mucositis scores in osteosarcoma. Therapeutic Drug Monitoring , 33 (6) 711 - 718. 10.1097/FTD.0b013e31823615e1.

K

Khan, MS; El-Khouly, F; Toumpanakis, C; Meyer, T; Caplin, M; Luong, TV; (2011) Ki-67 is a Better Prognostic Marker than Mitotic Count in Neuroendocrine Tumors. In: NEUROENDOCRINOLOGY. (pp. 31 - 31).

Khan, MS; Tsigani, T; Garcia-Hernandez, J; Caplin, M; Meyer, T; (2011) Circulating Tumor Cells (CTCs) Correlate with Overall Survival in Neuroendocrine Tumors (NETs). In: NEUROENDOCRINOLOGY. (pp. 31 - 31).

Kristeleit, RS; baird, R; venugopal, B; wilkins, D; maccormick, F; granata, R; ... de bono, J; + view all (2011) Cardiac effects in a first-in-human (FIH), pharmacokinetic (PK), pharmacodynamic (PD) phase I trial of JNJ-26481585, a second-generation oral hydroxamate histone deacetylase inhibitor (HDACi), in patients with refractory cancer. In: Molecular Cancer Therapeutics.

Kulkarni, S; Sitaru, C; Jakus, Z; Anderson, KE; Damoulakis, G; Davidson, K; ... Hawkins, PT; + view all (2011) PI3Kβ plays a critical role in neutrophil activation by immune complexes. Sci Signal , 4 (168) ra23 - ?. 10.1126/scisignal.2001617.

L

Lafont, E; Kitatani, K; Okazaki, T; Ségui, B; (2011) Regulation of death and growth signals at the plasma membrane by sphingomyelin synthesis: implications for hematological malignancies. Recent Pat Anticancer Drug Discov , 6 (3) 324 - 333.

Lee, AJ; Endesfelder, D; Rowan, AJ; Walther, A; Birkbak, NJ; Futreal, PA; ... Swanton, C; + view all (2011) Chromosomal instability confers intrinsic multidrug resistance. Cancer Res , 71 (5) 1858 - 1870. 10.1158/0008-5472.CAN-10-3604.

Lemech, C; Arkenau, H-T; (2011) Biomarkers in advanced colorectal cancer: Challenges in translating clinical research into practice. Cancers , 3 (2) 1844 - 1860. 10.3390/cancers3021844. Gold open access

Lemech, CR; Kristeleit, RS; Arkenau, H; (2011) Novel Oncology drug development strategies in the era of personalised medicine. In: Drug Discovery and Development. InTech

Liccardi, G.; (2011) Nuclear EGFR modulation of DNA repair. Doctoral thesis, UCL (University College London). Green open access
file

Liu, H; Wang, W; Chew, SK; Lee, SC; Li, J; Vassiliou, GS; ... Liu, P; + view all (2011) Stella-Cre mice are highly efficient Cre deleters. Genesis , 49 (8) 689 - 695. 10.1002/dvg.20741.

Lowe, H.L.; (2011) Design, construction and evaluation of a humanised ADEPT system. Doctoral thesis, UCL (University College London).

M

Mansur, A; Little, MA; Oh, WC; Jacques, S; Nightingale, P; Howie, AJ; Savage, CO; (2011) Immune profile and Epstein-Barr virus infection in acute interstitial nephritis: an immunohistochemical study in 78 patients. Nephron Clin Pract , 119 (4) c293 - c300. 10.1159/000329671.

Maughan, TS; Adams, RA; Smith, CG; Meade, AM; Seymour, MT; Wilson, RH; ... MRC COIN Trial Investigators,; + view all (2011) Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial. Lancet , 377 (9783) 2103 - 2114. 10.1016/S0140-6736(11)60613-2.

P

Pors, K; Loadman, PM; Shnyder, SD; Sutherland, M; Sheldrake, HM; Guino, M; ... Patterson, LH; + view all (2011) Modification of the duocarmycin pharmacophore enables CYP1A1 targeting for biological activity. CHEM COMMUN , 47 (44) 12062 - 12064. 10.1039/c1cc15638a.

Poiroux, G; Pitié, M; Culerrier, R; Lafont, E; Ségui, B; Van Damme, EJ; ... Benoist, H; + view all (2011) Targeting of T/Tn antigens with a plant lectin to kill human leukemia cells by photochemotherapy. PLoS One , 6 (8) , Article e23315. 10.1371/journal.pone.0023315. Green and gold open access
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R

Raja, FA; Griffin, CL; Qian, W; Hirte, H; Parmar, MK; Swart, AM; Ledermann, JA; (2011) Initial toxicity assessment of ICON6: a randomised trial of cediranib plus chemotherapy in platinum-sensitive relapsed ovarian cancer. BRIT J CANCER , 105 (7) 884 - 889. 10.1038/bjc.2011.334.

Rajkumar, V; Dearling, JL; Packard, A; Pedley, RB; (2011) Radioimmunotherapy: optimizing delivery to solid tumors. Ther Deliv , 2 (5) 567 - 572.

Ran, Y; Ethaar, E-E; Vineeth, R; Mathew, R; Barbara, PR; Erik, A; (2011) One-pot Formation of a I-125-labeled Trifunctional Reagent for Multiscale Imaging with Optical and Nuclear Techniques. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS , 54 S57 - S57.

Reid, JM; Buhrow, SA; Kuffel, MJ; Jia, L; Spanswick, VJ; Hartley, JA; ... Ames, MM; + view all (2011) Pharmacokinetics, pharmacodynamics and metabolism of the dimeric pyrrolobenzodiazepine SJG-136 in rats. CANCER CHEMOTH PHARM , 68 (3) 777 - 786. 10.1007/s00280-010-1517-4.

Rizza, SA; Challagundla, KB; Natesampillai, S; Bren, GD; Sykora, J; Walczak, H; Badley, AD; (2011) TRAIL Dependent Fratricidal Killing of gp120 Primed Hepatocytes by HCV Core Expressing Hepatocytes. PLoS ONE , 6 (11) , Article e27171. 10.1371/journal.pone.0027171. Green and gold open access
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S

Salazar, R; Plummer, R; Oaknin, A; Robinson, A; Pardo, B; Soto-Matos, A; ... Calvert, AH; + view all (2011) Phase I study of weekly plitidepsin as 1-hour infusion combined with carboplatin in patients with advanced solid tumors or lymphomas. INVEST NEW DRUG , 29 (6) 1406 - 1413. 10.1007/s10637-010-9488-1.

Saravanan, K; Barlow, HC; Barton, M; Calvert, AH; Golding, BT; Newell, DR; ... Griffin, RJ; + view all (2011) Nucleoside Transport Inhibitors: Structure-Activity Relationships for Pyrimido[5,4-d]pyrimidine Derivatives That Potentiate Pemetrexed Cytotoxicity in the Presence of alpha(1)-Acid Glycoprotein. J MED CHEM , 54 (6) 1847 - 1859. 10.1021/jm101493z.

Short, SC; Giampieri, S; Worku, M; German, M; Sioftanos, G; Bourne, S; (2011) Rad51 inhibition is an effective means of targeting DNA repair in glioma models and CD133+ tumour derived cells. Neuro-Oncology , 13 (5) 487 - 499.

Siddiqui, GK; Maclean, AB; Elmasry, K; Fong, AWT; Morris, RW; Rashid, M; ... Boxer, GM; + view all (2011) Immunohistochemical expression of VEGF predicts response to platinum based chemotherapy in patients with epithelial ovarian cancer. ANGIOGENESIS , 14 (2) 155 - 161. 10.1007/s10456-010-9199-4.

Spencer, J; Amin, J; Coxhead, P; McGeehan, J; Richards, CJ; Tizzard, GJ; ... Guille, M; + view all (2011) Size Does Matter. Sterically Demanding Metallocene-Substituted 3-Methylidene-Oxindoles Exhibit Poor Kinase Inhibitory Action. ORGANOMETALLICS , 30 (11) 3177 - 3181. 10.1021/om200278j.

T

Taylor, RM; Grieve, A; Gibson, F; Dhawan, A; Franck, LS; (2011) Parental assessment of adolescent quality of life: can it replace self-assessment? Qual Life Res , 20 (10) 1715 - 1720. 10.1007/s11136-011-9904-9.

V

Vazquez, I; Bridgewater, J; (2011) Nonsurgical therapy of biliary tract cancer. Curr Opin Gastroenterol , 27 (3) 258 - 261. 10.1097/MOG.0b013e3283454f09.

W

Wen, PJ; Osborne, SL; Zanin, M; Low, PC; Wang, HT; Schoenwaelder, SM; ... Meunier, FA; + view all (2011) Phosphatidylinositol(4,5)bisphosphate coordinates actin-mediated mobilization and translocation of secretory vesicles to the plasma membrane of chromaffin cells. Nat Commun , 2 491 - ?. 10.1038/ncomms1500.

Whelan, JS; Gelderblom, AH; Jinks, R; Sydes, M; Bramwell, VH; van Glabbeke, M; ... Taminiau, AHM; + view all (2011) Survival after recurrent osteosarcoma: data from 3 European Osteosarcoma Intergroup randomised controlled trials. Eur J Cancer (47) 895 - 902.

Whelan, JS; Jinks, RC; McTiernan, A; Sydes, MR; Hook, JM; Trani, L; ... Gelderblom, H; + view all (2011) Survival from high-grade localised extremity osteosarcoma: combined results and prognostic factors from three European Osteosarcoma Intergroup randomised controlled trials. Ann Oncol 10.1093/annonc/mdr491.

Whelan, JS; Miller, R; (2011) Lung carcinoma with hypertropic osteoarthropathy in a teenager. Rare Tumours , 3:e8

Whiteford, JR; Xian, X; Chaussade, C; Vanhaesebroeck, B; Nourshargh, S; Couchman, JR; (2011) Syndecan-2 is a novel ligand for the protein tyrosine phosphatase receptor CD148. Mol Biol Cell , 22 (19) 3609 - 3624. 10.1091/mbc.E11-02-0099.

Wykosky, J; Fenton, T; Furnari, F; Cavenee, WK; (2011) Therapeutic targeting of epidermal growth factor receptor in human cancer: successes and limitations. Chin J Cancer , 30 (1) 5 - 12. Gold open access

Y

Yan, R; El-Emir, E; Rajkumar, V; Robson, M; Jathoul, AP; Pedley, RB; Arstad, E; (2011) One-Pot Synthesis of an I-125-Labeled Trifunctional Reagent for Multiscale Imaging with Optical and Nuclear Techniques. ANGEW CHEM INT EDIT , 50 (30) 6793 - 6795. 10.1002/anie.201102072.

Yong, MY; Gonzalez-Beltran, A; Begent, R; (2011) Establishing a knowledge trail from molecular experiments to clinical trials. NEW BIOTECHNOL , 28 (5) 464 - 480. 10.1016/j.nbt.2011.03.016.

This list was generated on Sun Dec 14 07:44:45 2014 GMT.