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Number of items: 78.

A

Amrolia, PJ and Almeida, A and Davies, SC and Roberts, IA (2003) Therapeutic challenges in childhood sickle cell disease. Part 2: a problem-orientated approach. Br J Haematol , 120 (5) 737 - 743.

Amrolia, PJ and Almeida, A and Halsey, C and Roberts, IA and Davies, SC (2003) Therapeutic challenges in childhood sickle cell disease. Part 1: current and future treatment options. Br J Haematol , 120 (5) 725 - 736.

Amrolia, PJ and Muccioli-Casadei, G and Yvon, E and Huls, H and Sili, U and Wieder, ED and Bollard, C and Heslop, HE and Molldrem, JJ and Rooney, CM and Brenner, MK (2003) Selective depletion of donor allo-reactive T-cells without loss of anti-viral or anti-leukemic responses. Blood , 102 (6) 2292 - 2299. 10.1182/blood-2002-11-3516.

Amrolia, PJ and Reid, SD and Gao, LQ and Schultheis, B and Dotti, G and Brenner, MK and Melo, JV and Goldman, JM and Stauss, HJ (2003) Allorestricted cytotoxic T cells specific for human CD45 show potent antileukemic activity. BLOOD , 101 (3) 1007 - 1014. 10.1182/blood-2002-02-0525.

Antoine, C and Müller, S and Cant, A and Cavazzana-Calvo, M and Veys, P and Vossen, J and Fasth, A and Heilmann, C and Wulffraat, N and Seger, R and Blanche, S and Friedrich, W and Abinun, M and Davies, G and Bredius, R and Schulz, A and Landais, P and Fischer, A and European Group for Blood and Marrow Transplantation, and European Society for Immunodeficiency, (2003) Long-term survival and transplantation of haemopoietic stem cells for immunodeficiencies: report of the European experience 1968-99. Lancet , 361 (9357) 553 - 560.

B

Bainbridge, JWB and Mistry, A and Binley, K and De Alwis, M and Thrasher, AJ and Naylor, S and Ali, RR (2003) Hypoxia-regulated transgene expression in experimental retinal and choroidal neovascularization. GENE THER , 10 (12) 1049 - 1054. 10.1038/sj.gt.3301945.

Bainbridge, JWB and Mistry, A and Schlichtenbrede, FC and Smith, A and Broderick, C and De Alwis, M and Georgiadis, A and Taylor, PM and Squires, M and Sethi, C and Charteris, D and Thrasher, AJ and Sargan, D and Ali, RR (2003) Stable rAAV-mediated transduction of rod and cone photoreceptors in the canine retina. GENE THER , 10 (16) 1336 - 1344. 10.1038/sj.gt.3301990.

Bainbridge, JWB and Mistry, AR and Thrasher, AJ and Ali, RR (2003) Gene therapy for ocular angiogenesis. CLINICAL SCIENCE , 104 (6) 561 - 575.

Biagi, E and Yvon, E and Dotti, G and Amrolia, PJ and Takahashi, S and Popat, U and Marini, F and Andreeff, M and Brenner, MK and Rousseau, RF (2003) Bystander Transfer of Functional Human CD40 Ligand from Gene-Modified Fibroblasts to B-Chronic Lymphocytic Leukemia Cells. Human Gene Therapy , 14 (6) 545 - 559.

Brown, JR and Goldblatt, D and Buddle, J and Morton, L and Thrasher, AJ (2003) Diminished production of anti-inflammatory mediators during neutrophil apoptosis and macrophage phagocytosis in chronic granulomatous disease (CGD). J LEUKOCYTE BIOL , 73 (5) 591 - 599.

Buckland, KF and Williams, TJ and Conroy, DM (2003) Histamine induces cytoskeletal changes in human eosinophils via the H-4 receptor. BRIT J PHARMACOL , 140 (6) 1117 - 1127. 10.1038/sj.bjp.0705530.

Buckland, KF and Williams, TJ and Conroy, DM (2003) Histamine induces shape change and actin polymerisation in human eosinophils via the novel H-4 receptor. In: BRITISH JOURNAL OF PHARMACOLOGY. (pp. U22 - U22). NATURE PUBLISHING GROUP

Burgess, J and Bedford, T and Hobson, G and Davies, G and Harrison, C (2003) (Un)sustainable consumption. In: Berkhout, F and Leach, M and Scoones, I, (eds.) Negotiating Environmental Change: New Perspectives from Social Science. (261 - 292). Edward Elgar: Cheltenham.

C

Cannon, M and Philpott, NJ and Cesarman, E (2003) The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor has broad signaling effects in primary effusion lymphoma cells. Journal of Virology , 77 (1) 57 - 67.

Clark, R.H. and Stinchcombe, J.C. and Day, A. and Blott, E. and Booth, S. and Bossi, G. and Hamblin, T. and Davies, E.G. and Griffiths, G.M. (2003) Adaptor protein 3–dependent microtubule-mediated movement of lytic granules to the immunological synapse. Nature Immunology , 4 (11) pp. 1111-1120. 10.1038/ni1000.

Clark, RH and Stinchcombe, JC and Day, A and Blott, E and Booth, S and Bossi, G and Hamblin, T and Davies, EG and Griffiths, GM (2003) Adaptor protein 3-dependent microtubule-mediated movement of lytic granules to the immunological synapse. Nature Immunology , 4 (11) 1111 - 1120. 10.1038/ni1000.

D

Davies, G and Keir, G and Thompson, EJ and Giovannoni, G (2003) The clinical significance of an intrathecal monoclonal immunoglobulin band - A follow-up study. NEUROLOGY , 60 (7) 1163 - 1166.

E

Edwards, SW and Moulding, DA and Derouet, M and Moots, RJ (2003) Regulation of neutrophil apoptosis. CHEM IMMUNOL , 83 204 - 224.

Erlandsson, K and Visvikis, D and Waddington, WA and Cullum, ID and Davies, G (2003) Absolute quantification with hybrid PET/CT and SPET/CT systems. In: Nuclear Medicine Communications. (pp. 456 - 457).

F

Ferretti, P and Zhang, F and O'Neill, P (2003) Changes in spinal cord regenerative ability through phylogenesis and development: Lessons to be learnt. DEV DYNAM , 226 (2) 245 - 256. 10.1002/dvdy.10226.

Fieschi, C and Dupuis, S and Catherinot, E and Feinberg, J and Bustamante, J and Breiman, A and Altare, F and Baretto, R and Le Deist, F and Kayal, S and Koch, H and Richter, D and Brezina, M and Aksu, G and Wood, P and Al Jumaah, S and Raspall, M and Silva Duarte, AJ and Tuerlinckx, D and Virelizier, JL and Fischer, A and Enright, A and Bernhoft, J and Cleary, AM and Vermylen, C and Rodriguez-Gallego, C and Davies, G and Blutters-Sawatzki, R and Siegrist, CA and Ehlayel, MS and Novelli, V and Haas, WH and Levy, J and Freihorst, J and Al Hajjar, S and Nadal, D and Moraes Vasconcelos, D and Jeppsson, O and Kutukculer, N and Frecerova, K and Caragol, I and Lammas, D and Kumararatne, DS and Abel, L and Casanova, JL (2003) Low penetrance, broad resistance, and favorable outcome of interleukin 12 receptor beta1 deficiency: medical and immunological implications. Journal of Experimental Medicine , 197 (4) 527 - 535.

Fossati, G and Moulding, DA and Spiller, DG and Moots, RJ and White, MRH and Edwards, SW (2003) The mitochondrial network of human neutrophils: Role in chemotaxis, phagocytosis, respiratory burst activation, and commitment to apoptosis. J IMMUNOL , 170 (4) 1964 - 1972.

G

Gaspar, HB and Howe, S and Thrasher, AJ (2003) Gene therapy progress and prospects: gene therapy for severe combined immunodeficiency. Gene Ther , 10 (24) 1999 - 2004. 10.1038/sj.gt.3302150.

Giampaoli, S and Bucci, S and Ragghianti, M and Mancino, G and Zhang, F and Ferretti, P (2003) Expression of FGF2 in the limb blastema of two Salamandridae correlates with their regenerative capability. P R SOC B , 270 (1530) 2197 - 2205. 10.1098/rspb.2003.2439.

Gilmour, KC and Gaspar, HB (2003) Pathogenesis and diagnosis of X-linked lymphoproliferative disease. EXPERT REV MOL DIAGN , 3 (5) 549 - 561.

H

Hart, SL (2003) Large animal models: bridging the gap. Mol Ther , 8 (4) 528 - 529.

Howe, S and Thrasher, A (2003) Gene therapy for inherited immunodeficiencies. Current Hematology Reports , 2 283 - 334.

Howe, S and Thrasher, AJ (2003) Gene therapy for inherited immunodeficiencies. Curr Hematol Rep , 2 (4) 328 - 334.

Hsu, C and Boysen, MM and Gritton, LD and Writer, MJ and Devitt, JPR and Hart, SL and Von Seggern, DJ (2003) Targeting of dendritic cells by pseudotyped and peptide-modified adenovirus vectors. In: MOLECULAR THERAPY. (pp. S469 - S470). ACADEMIC PRESS INC ELSEVIER SCIENCE

Hurley, CA and Hailes, HC and Tabor, AB and Hart, SL (2003) Complexes for the Delivery of Biologically-Active Material to Cells. 2003094974.

J

Jenkins, R.G. and Meng, Q.-H. and Hodges, R.J. and Lee, L.K. and Bottoms, S.E.W. and Laurent, G.J. and Willis, D. and Shamlou, P.A. and McAnulty, R.J. and Hart, S.L. (2003) Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo. Gene Therapy , 10 (12) pp. 1026-1034. 10.1038/sj.gt.3301963.

Jenkins, R.G. and Meng, Q.-H. and Hodges, R.J. and Lee, L.K. and Bottoms, S.E.W. and Laurent, G.J. and Willis, D. and Shamlou, P.A. and McAnulty, R.J. and Hart, S.L. (2003) Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo. Gene Therapy , 10 (12) pp. 1026-1034. 10.1038/sj.gt.3301963.

Jenkins, RG and McAnulty, RJ and Hart, SL and Laurent, GJ (2003) Pulmonary Gene Therapy. Realistic hope for the future, or false dawn in the promised land? Monaldi Arch Chest Dis , 59 (1) 21 - 28.

Jenkins, RG and McAnulty, RJ and Hart, SL and Laurent, GJ (2003) Pulmonary gene therapy. Realistic hope for the future, or false dawn in the promised land? Monaldi Arch Chest Dis , 59 (1) 17 - 24.

Jenkins, RG and Meng, QHH and Hodges, RJ and Lee, LK and Bottoms, SEW and Laurent, GJ and Willis, D and Shamlou, PA and McAnulty, RJ and Hart, SL (2003) Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo. GENE THER , 10 (12) 1026 - 1034. 10.1038/sj.gt.3301963.

L

Lawson, SE and Roberts, IA and Amrolia, P and Dokal, I and Szydlo, R and Darbyshire, PJ (2003) Bone marrow transplantation for beta-thalassaemia major: the UK experience in two paediatric centres. British Journal of Haematology , 120 (2) 289 - 295.

Lee, LK and Siapati, EK and Jenkins, RG and McAnulty, RJ and Hart, SL and Shamlou, PA (2003) Biophysical characterization of an integrin-targeted non-viral vector. Med Sci Monit , 9 (1) BR54 - BR61.

Leonardi, A and Jose, PJ and Zhan, H and Calder, VL (2003) Tear and mucus eotaxin-l and eotaxin-2 in allergic keratoconjunctivitis. OPHTHALMOLOGY , 110 (3) 487 - 492. 10.1016/S0161-6420(02)01767-0.

M

Maiuri, L and Ciacci, C and Ricciardelli, I and Vacca, L and Raia, V and Auricchio, S and Picard, J and Osman, M and Quaratino, S and Londei, M (2003) Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease. LANCET , 362 (9377) 30 - 37.

Marden, C and Graham, DC and Thrasher, A and Casimir, C (2003) A functional ISRE is required for myeloid transcription of the p47 phox gene. Biochimica et Biophysica Acta - Gene Structure and Expression , 1630 (2-3) 117 - 122.

Mistry, A and Harbottle, R and Hart, S and Hodivala-Dilke, KM (2003) Integrins and angiogenesis: unlocking the route to gene therapy. Current Opinion in Molecular Therapeutics , 5 (6) 603 - 610.

N

Nabarro, S and Thrasher, AJ and Kempski, H and Amrolia, P and Anderson, J (2003) Generation of immunostimulatory dendritic cells from the malignant clone in patients with juvenile myelomonocytic leukemia [5]. Leukemia , 17 (9) 1910 - 1912.

P

Pacchia, AL and Mukherjee, S and Dougherty, JP (2003) Choice and use of appropriate packaging cell types. Methods Mol.Biol. , 229 29 - 42.

Picard, C and Puel, A and Bonnet, M and Ku, CL and Bustamante, J and Yang, K and Soudais, C and Dupuis, S and Feinberg, J and Fieschi, C and Elbim, C and Hitchcock, R and Lammas, D and Davies, G and Al Ghonaium, A and Al Rayes, H and Al Jumaah, S and Al Hajjar, S and Al Mohsen, IZ and Frayha, HH and Rucker, R and Hawn, TR and Aderem, A and Tufenkeji, H and Haraguchi, S and Day, NK and Good, RA and Gougerot-Pocidalo, MA and Ozinsky, A and Casanova, JL (2003) Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science , 299 (5615) 2076 - 2079. 10.1126/science.1081902.

Picard, C. and Puel, A. and Bonnet, M. and Ku, C.-L. and Bustamante, J. and Yang, K. and Soudais, C. and Dupuis, S. and Feinberg, J. and Fieschi, C. and Elbim, C. and Hitchcock, R. and Lammas, D. and Davies, G. and Al-Ghonaium, A. and Al-Rayes, H. and Al-Jumaah, S. and Al-Hajjar, S. and Al-Mohsen, I.Z. and Frayha, H.H. and Rucker, R. and Hawn, T.R. and Aderem, A. and Tufenkeji, H. and Haraguchi, S. and Day, N.K. and Good, R.A. and Gougerot-Pocidalo, M.-A. and Ozinsky, A. and Casanova, J.-L. (2003) Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science , 299 (5615) pp. 2076-2079. 10.1126/science.1081902.

Pilkington-Miksa, MA and Tabor, AB and Hailes, HC and Hart, SL and Writer, M and Shamlou, PA and Sarkar, S (2003) Synthesis of unusual integrin-binding peptides for inclusion into LID transfection complexes. In: MOLECULAR THERAPY. (pp. S217 - S218). ACADEMIC PRESS INC ELSEVIER SCIENCE

Pilkington-Miksa, MA and Tabor, AB and Hart, SL and Hailes, HC and Writer, M and Shamlou, PA and Sarkhar, S (2003) Synthesis of Unusual Integrin-Binding Peptides for Inclusion into LID Transfection Complexes. In: Molecular Therapy. (pp. S217 - S217).

Q

Qasim, W and King, D and Buddle, J and Verfuerth, S and Kinnon, C and Thrasher, AJ and Gaspar, HB (2003) The impact of retroviral suicide gene transduction procedures on T cells. BRIT J HAEMATOL , 123 (4) 712 - 719.

Qasim, W and Kinnon, C and King, D and Thrasher, AJ and Gaspar, B (2003) Analysis of T cell functionality following retroviral mediated suicide gene transfer. In: MOLECULAR THERAPY. (pp. S282 - S282). ACADEMIC PRESS INC ELSEVIER SCIENCE

Qasim, W and Thrasher, A and Buddle, J and King, D and Kinnon, C and Gaspar, H (2003) Retroviral transduction and selection of T-cells for suicide gene therapy. In: BONE MARROW TRANSPLANTATION. (pp. S105 - S106). NATURE PUBLISHING GROUP

R

Roche, AC and Fajac, I and Grosse, S and Frison, N and Rondanino, C and Mayer, R and Monsigny, M (2003) Glycofection: facilitated gene transfer by cationic glycopolymers. Cell Mol Life Sci , 60 (2) 288 - 297.

S

Sarkar, S and Zhang, H and Levy, SM and Hart, SL and Hailes, HC and Tabor, AB and Shamlou, PA (2003) Prediction of size distribution of lipid-peptide-DNA vector particles using Monte Carlo simulation techniques. BIOTECHNOL APPL BIOC , 38 95 - 102.

Santilli, G and Aronow, BJ and Sala, A (2003) Essential requirement of apolipoprotein J (clusterin) signaling for I kappa B expression and regulation of NF-kappa B activity. J BIOL CHEM , 278 (40) 38214 - 38219. 10.1074/jbc.C300252200.
An open access publication

Santilli, G and Aronow, BJ and Sala, A (2003) Essential requirement of Apolipoprotein J (clusterin) signalling for IKB expression and modulation of NF-kB activity: Implications for neuroblastoma. In: BRITISH JOURNAL OF CANCER. (pp. S67 - S67). NATURE PUBLISHING GROUP

Sarkar, S and Zhang, H and Levy, MS and Hart, SL and Hailes, HC and Tabor, AB and Shamlou, PA (2003) Impact of biophysical and chemical properties of non-viral vector formulation on cell transfection. In: (Proceedings) AIChE Annual Conference. : San Francisco.

Schlichtenbrede, FC and da Cruz, L and Stephens, C and Smith, AJ and Georgiadis, A and Thrasher, AJ and Bainbridge, JWB and Seeliger, MW and Ali, RR (2003) Long-term evaluation of retinal function in Prph2(Rd2/Rd2) mice following AAV-mediated gene replacement therapy. J GENE MED , 5 (9) 757 - 764. 10.1002/jgm.401.

Schlichtenbrede, FC and MacNeil, A and Bainbridge, JWB and Tschernutter, M and Thrasher, AJ and Smith, AJ and Ali, RR (2003) Intraocular gene delivery of ciliary neurotrophic factor results in significant loss of retinal function in normal mice and in the Prph2(Rd2/Rd2) model of retinal degeneration. GENE THER , 10 (6) 523 - 527. 10.1038/sj.gt.3301929.

Sebire, NJ and Haselden, S and Malone, M and Davies, EG and Ramsay, AD (2003) Isolated EBV lymphoproliferative disease in a child with Wiskott-Aldrich syndrome manifesting as cutaneous lymphomatoid granulomatosis and responsive to anti-CD20 immunotherapy. J CLIN PATHOL , 56 (7) 555 - 557.

Sharifi, R and Buddle, J and Gilmour, KC and Kinnon, C and Thrasher, AJ and Gaspar, B (2003) Cytotoxic T cell defects in x-linked Lymphoproliferative disease and reconstitution of abnormalities by SAP gene transfer. In: MOLECULAR THERAPY. (pp. S408 - S408). ACADEMIC PRESS INC ELSEVIER SCIENCE

Siapati, KE and Barker, S and Kinnon, C and Michalski, A and Anderson, R and Brickell, P and Thrasher, AJ and Hart, SL (2003) Improved antitumour immunity in murine neuroblastoma using a combination of IL-2 and IL-12. BRIT J CANCER , 88 (10) 1641 - 1648. 10.1038/sj.bjc.6600928.

Smith, AJ and Schlichtenbrede, FC and Tschernutter, M and Bainbridge, JW and Thrasher, AJ and Ali, RR (2003) AAV-mediated gene transfer slows photoreceptor loss in the RCS rat model of retinitis pigmentosa. MOL THER , 8 (2) 188 - 195. 10.1016/S1525-0016(03)00144-8.

T

Tan, PH and Manunta, M and Ardjomand, N and Xue, SA and Larkin, DFP and Haskard, DO and Taylor, KM and George, AJT (2003) Antibody targeted gene transfer to endothelium. J GENE MED , 5 (4) 311 - 323. 10.1002/jgm.358.

Trip, SA and Wroe, SJ and Davies, G and Giovannoni, G (2003) Primary CNS mantle cell lymphoma associated with an isolated CSF monoclonal IgG band. EUR NEUROL , 49 (3) 187 - 188. 10.1159/000069080.

U

Uduehi, A and Mailhos, C and Truman, H and Thrasher, AJ and Kinnon, C and Hart, SL (2003) Enhancement of integrin-mediated transfection of haematopoietic cells with a synthetic vector system. BIOTECHNOL APPL BIOC , 38 201 - 209. 10.1042/BA20030062.

V

Veys, P and Amrolia, P and Rao, K (2003) The role of haploidentical stem cell transplantation in the management of children with haematological disorders. Br J Haematol , 123 (2) 193 - 206.

W

Walder, S and Zhang, F and Ferretti, P (2003) Up-regulation of neural stem cell markers suggests the occurrence of dedifferentiation in regenerating spinal cord. DEV GENES EVOL , 213 (12) 625 - 630. 10.1007/s00427-003-0364-2.

Westerberg, L and Hardy, S and Greicius, G and Thrasher, AJ and Severinson, E (2003) B cell and splenic abnormalities in Wiskott-Aldrich syndrome. In: FASEB JOURNAL. (pp. C105 - C105). FEDERATION AMER SOC EXP BIOL

White, RE and Wade-Martins, R and Hart, SL and Frampton, J and Huey, B and Desai-Mehta, A and Cerosaletti, KM and Concannon, P and James, MR (2003) Functional delivery of large genomic DNA to human cells with a peptide-lipid vector. J GENE MED , 5 (10) 883 - 892. 10.1002/jgm.420.

Whitehead, BF and Schofield, R and Rogers, KM and Gustafsson, K and Fabre, JW (2003) Modulation of adenovirus infection in vitro by antisense oligodeoxynucleotides. Respirology , 8 (3) 310 - 315.

Worth, A and Rao, K and Webb, D and Chessells, J and Passmore, J and Veys, P (2003) Successful treatment of juvenile myelomonocytic leukemia relapsing after stem cell transplantation using donor lymphocyte infusion. Blood , 101 (5) 1713 - 1714. 10.1182/blood-2002-07-2011.

Worth, A. and Rao, K. and Webb, D. and Chessells, J. and Passmore, J. and Veys, P. (2003) Successful treatment of juvenile myelomonocytic leukemia relapsing after stem cell transplantation using donor lymphocyte infusion. Blood , 101 (5) pp. 1713-1714. 10.1182/blood-2002-07-2011.

Writer, MJ and Hsu, C and Devitt, J and Tabor, AB and Kinnon, C and Von Seggern, D and Hart, SL (2003) Increased efficiency of gene transfer into dendritic cells using phage display-derived peptides. In: MOLECULAR THERAPY. (pp. S469 - S469). ACADEMIC PRESS INC ELSEVIER SCIENCE

Y

Yvon, ES and Vigouroux, S and Rousseau, RF and Biagi, E and Amrolia, P and Dotti, G and Wagner, HJ and Brenner, MK (2003) Over expression of the Notch ligand, Jagged-1 induces alloantigen-specific human regulatory T cells. Blood

Z

Zhan, H and Calder, V and Lightman, S (2003) T-cell characterization in chronic allergic eye disease. Curr Allergy Asthma Rep , 3 (4) 358 - 362.

Zhan, H and Leonardi, A and Calder, VL (2003) Cytokine regulation of chemokines in conjunctival epithelial cells and fibroblasts. In: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. (pp. U316 - U316). ASSOC RESEARCH VISION OPHTHALMOLOGY INC

Zhan, H and Smith, L and Calder, V and Buckley, R and Lightman, S (2003) Clinical and immunological features of atopic keratoconjunctivitis. Int Ophthalmol Clin , 43 (1) 59 - 71.

Zhan, H and Towler, HMAT and Calder, VL (2003) The immunomodulatory role of human conjunctival epithelial cells. INVEST OPHTH VIS SCI , 44 (9) 3906 - 3910. 10.1167/iovs.02-0665.

Zhang, F and Ferretti, P and Clarke, JDW (2003) Recruitment of postmitotic neurons into the regenerating spinal cord of urodeles. DEV DYNAM , 226 (2) 341 - 348. 10.1002/dvdy.10230.

This list was generated on Wed Jun 12 10:09:03 2013 BST.