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Number of items: 74.

A

Amrolia, PJ and Mucioli-Casadei, G and Huls, H and Heslop, HE and Schindler, J and Veys, P and Vitetta, ES and Brenner, MK (2005) Add-back of allodepleted donor T cells to improve immune reconstitution after haplo-identical stem cell transplantation. Cytotherapy , 7 (2) 116 - 125.

B

Bailey, SI and Howe, S and Schambach, A and Bohne, J and Russell, DW and Baum, C and Thrasher, AJ (2005) Investigating novel retroviral vectors for the treatment of SCID-X1. In: BSGT Manchester 2005.

Blundell, MP and Charrier, S and Kinnon, C and Galy, A and Thrasher, AJ (2005) Lentiviral gene therapy for Wiskotot Aldrich Syndrome. In: BSGT Manchester 2005.

Bouma, G and Coppens, JMC and Lam-Tse, WK and Luini, W and Sintnicolaas, K and Levering, WH and Sozzani, S and Drexhage, HA and Versnel, MA (2005) An increased MRP8/14 expression and adhesion, but a decreased migration towards proinflammatory chemokines of type 1 diabetes monocytes. CLIN EXP IMMUNOL , 141 (3) 509 - 517. 10.1111/j.1365-2249.2005.02865.x.
An open access publication

Bouma, G and Coppens, JMC and Mourits, S and Nikolic, T and Sozzani, S and Drexhage, HA and Versnel, MA (2005) Evidence for an enhanced adhesion of DC to fibronectin and a role of CCL19 and CCL21 in the accumulation of DC around the pre-diabetic islets in NOD mice. EUR J IMMUNOL , 35 (8) 2386 - 2396. 10.1002/eji.200526251.

Bouma, G and Nikolic, T and Coppens, JMC and van Helden-Meeuwsen, CG and Leenen, PJM and Drexhage, HA and Sozzani, S and Versnel, MA (2005) NOD mice have a severly impaired ability to recruit leukocytes into sites of inflammation. EUR J IMMUNOL , 35 (1) 225 - 235. 10.1002/eji.200425513.

Broderick, CA and Smith, AJ and Balaggan, KS and Georgarias, A and Buch, PK and Trittibach, PC and Barker, SE and Sarra, GM and Thrasher, AJ and Dick, AD and Ali, RR (2005) Local administration of an adeno-associated viral vector expressing IL-10 reduces monocyte infiltration and subsequent photoreceptor damage during experimental autoimmune uveitis. MOL THER , 12 (2) 369 - 373. 10.1016/j.ymthe.2005.03.018.

Brooke, NJ and Antonious, M and Thrasher, AJ (2005) To be announced. In: BSGT Manchester 2005.

C

Carpenter, KJ and Buckland, KF and Xing, Z and Hogaboam, CM (2005) Intrapulmonary, adenovirus-mediated overexpression of KARAP/DAP12 enhances fungal clearance during invasive aspergillosis. INFECT IMMUN , 73 (12) 8402 - 8406. 10.1128/IAI.73.12.8402-8406.2005.

Charrier, S and Dupre, L and Blundell, M and Scaramuzza, S and Jeanson, L and Vainchenker, W and Danos, O and Roncarolo, MG and Thrasher, A and Galy, A (2005) Functional correction of lymphocytes and dendritic cells of patients with WAS or XLT, using lentiviral vectors targeting the expression of WAS protein to hematopoietic cells. Blood , 106 (11) 852A - 852A.

Cohen, J and Gandhi, M and Naik, P and Cubitt, D and Rao, K and Thaker, U and Davies, EG and Gaspar, HB and Amrolia, PJ and Veys, P (2005) Increased incidence of EBV-related disease following paediatric stem cell transplantation with reduced-intensity conditioning. Br J Haematol , 129 (2) 229 - 239. 10.1111/j.1365-2141.2005.05439.x.

Cui, ZQ and Tuladhar, R and Hart, SL and Marber, MS and Pearson, JD and Baydoun, AR (2005) Rate of transport of L-arginine is independent of the expression of inducible nitric oxide synthase in HEK 293 cells. NITRIC OXIDE-BIOL CH , 12 (1) 21 - 30. 10.1016/j.niox.2004.11.001.

D

de Noronha, S and Hardy, S and Sinclair, J and Blundell, MP and Strid, J and Schulz, O and Zwirner, J and Jones, GE and Katz, DR and Kinnon, C and Thrasher, AJ (2005) Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein. BLOOD , 105 (4) 1590 - 1597. 10.1182/blood-2004-06-2332.

de Noronha, S and Hardy, S and Sinclair, J and Blundell, MP and Strid, J and Schulz, O and Zwirner, J and Jones, GE and Katz, DR and Kinnon, C and Thrasher, AJ (2005) Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein. Blood , 105 (4) 1590 - 1597. 10.1182/blood-2004-06-2332.

G

Gaspar, HB and Bjorkegren, E and Parsley, K and Gilmour, KC and Sinclair, J and Zhang, F and Fairbanks, L and King, D and Davies, EG and Veys, P and Kinnon, C and Thrasher, AJ (2005) Somatic Gene Therapy for ADA-SCID following cessation of PEG-ADA and use of a mild conditioning regime. In: BSGT Manchester 2005.

Gaspar, HB and Bjorkegren, E and Parsley, K and Gilmour, KC and Sinclair, J and Zhang, F and Fairbanks, LD and King, D and Davies, G and Veys, P and Kinnon, C and Thrasher, AJ (2005) Somatic gene therapy for ADA-SCID following cessation of PEG-ADA and use of a mild conditioning regime. In:

Gaspar, HB and Thrasher, AJ (2005) Gene therapy for severe combined immunodeficiencies. Expert Opin Biol Ther , 5 (9) 1175 - 1182. 10.1517/14712598.5.9.1175.

Gompels, MM and Lock, RJ and Abinun, M and Bethune, CA and Davies, G and Grattan, C and Fay, AC and Longhurst, HJ and Morrison, L and Price, A and Price, M and Watters, D (2005) C1 inhibitor deficiency: consensus document. Clinical and Experimental Immunology , 139 (3) 379 - 394.

Grosse, S and Aron, Y and Thevenot, G and Francois, D and Monsigny, M and Fajac, I (2005) Potocytosis and cellular exit of complexes as cellular pathways for gene delivery by polycations. The Journal of Gene Medicine , 7 (10) 1275 - 1286. 10.1002/jgm.772.

Gustafsson, K and Durrbach, A and Seymour, RM and Pomiankowski, A (2005) The role of ABO histo-blood group antigens in viral infections. TRENDS GLYCOSCI GLYC , 17 (98) 285 - 294.

H

Hailes, HC and Tabor, AB and Wong, JB and Pilkington-Miksa, M and Hart, SL and Hurley, CA (2005) Preparation of Quaternary Ammonium Lipids and their Complexation with Peptides for Delivery to Cells. 20050245446.

Hart, SL (2005) Lipid carriers for gene therapy. Curr Drug Deliv , 2 (4) 423 - 428.

Hogaboam, CM and Carpenter, KJ and Schuh, JM and Buckland, KF (2005) Aspergillus and asthma - any link? MEDICAL MYCOLOGY , 43 S197 - S202. 10.1080/13693780400025211.

Hogaboam, CM and Carpenter, KJ and Schuh, JM and Proudfoot, AAEI and Bridger, G and Buckland, KF (2005) The therapeutic potential in targeting CCR5 and CXCR4 receptors in infectious and allergic pulmonary disease. PHARMACOL THERAPEUT , 107 (3) 314 - 328. 10.1016/j.pharmthera.2005.02.006.

K

Kampmann, B and Cubitt, D and Walls, T and Naik, P and Depala, M and Samarasinghe, S and Robson, D and Hassan, A and Rao, K and Gaspar, H and Davies, G and Jones, A and Cale, C and Gilmour, K and Real, M and Foo, M and Bennett-Rees, N and Hewitt, A and Amrolia, P and Veys, P (2005) Improved outcome for children with disseminated adenoviral infection following allogeneic stem cell transplantation. Br J Haematol , 130 (4) 595 - 603. 10.1111/j.1365-2141.2005.05649.x.

Kotzamanis, G and Cheung, W and Abdulrazzak, H and Perez-Luz, S and Howe, S and Cooke, H and Huxley, C (2005) Construction of human artificial chromosome vectors by recombineering. Gene , 351 (29) 38 - ?.

L

Lankester, AC and Visser, LF and Hartwig, NG and Bredius, RG and Gaspar, HB and van der, BM and van Tol, MJ and Gross, TG and Egeler, RM (2005) Allogeneic stem cell transplantation in X-linked lymphoproliferative disease: two cases in one family and review of the literature. BONE MARROW TRANSPLANT , 36 (2) 99 - 105.

Londei, M and Ciacci, C and Ricciardelli, I and Vacca, L and Quaratino, S and Maiuri, L (2005) Gliadin as a stimulator of innate responses in celiac disease. MOL IMMUNOL , 42 (8) 913 - 918. 10.1016/j.molimm.2004.12.005.

M

MacLaren, RE and Ali, RR and Thrasher, AJ (2005) Risks of gene therapy should be weighed against lack of alternatives for many diseases. BRIT MED J , 330 (7494) 791 - 791.

Maiuri, L and Ciacci, C and Ricciardelli, I and Vacca, L and Raia, V and Rispo, A and Griffin, M and Issekutz, T and Quaratino, S and Londei, M (2005) Unexpected role of surface transglutaminase type II in celiac disease. GASTROENTEROLOGY , 129 (5) 1400 - 1413. 10.1053/j.gastro.2005.07.054.

Martin, F and Toscano, MG and Blundell, M and Frecha, C and Srivastava, GK and Santamaria, M and Thrasher, AJ and Molina, IJ (2005) Lentiviral vectors transcriptionally targeted to hematopoietic cells by WASP gene proximal promoter sequences. GENE THER , 12 (8) 715 - 723. 10.1038/sj.gt.3302457.

Mohri, Z and Sperber, G and Manzano, A and TAGALAKIS, A and Dickson, G and Owen, JS (2005) Gene editing of the wild-type APOE3 gene to the dysfunctional variants APOE2 or APOE4 using synthetic RNA-DNA oligonucleotides (chimeraplasts). Gene Therapy and Molecular Biology , 9 143 - 152.

N

Nabarro, S and Himoudi, N and Papanastasiou, A and Gilmour, K and Gibson, S and Sebire, N and Thrasher, A and Blundell, MP and Hubank, M and Canderan, G and Anderson, J (2005) Coordinated oncogenic transformation and inhibition of host immune responses by the PAX3-FKHR fusion oncoprotein. Journal of Experimental Medicine , 202 (10) 1399 - 1410.
An open access version is available from UCL Discovery
file

Nabarro, S and Himoudi, N and Papanastasiou, A and Gilmour, K and Gibson, S and Sebire, N and Thrasher, A and Blundell, MP and Hubank, M and Canderan, G and Anderson, J (2005) Coordinated oncogenic transformation and inhibition of host immune responses by the PAX3-FKHR fusion oncoprotein. J EXP MED , 202 (10) 1399 - 1410.

Neil, S.J.D. and McKnight, A. and Gustafsson, K. and Weiss, R.A. (2005) HIV-1 incorporates ABO histo-blood group antigens that sensitize virions to complement-mediated inactivation. Blood , 105 (12) pp. 4693-4699. 10.1182/blood-2004-11-4267.

Neil, SJD and McKnight, A and Gustafsson, K and Weiss, RA (2005) HIV-1 incorporates ABO histo-blood group antigens that sensitize virions to complement-mediated inactivation. BLOOD , 105 (12) 4693 - 4699. 10.1182/blood-2004-11-4267.

Nikolic, T and Bouma, G and Drexhage, HA and Leenen, PJM (2005) Diabetes-prone NOD mice show an expanded subpopulation of mature circulating monocytes, which preferentially develop into macrophage-like cells in vitro. J LEUKOCYTE BIOL , 78 (1) 70 - 79. 10.1189/jlb.1104662.

P

Parsley, KL and Gaspar, HB and Howe, S and King, D and Gilmour, KG and Zhang, F and Sinclair, J and Von Kalle, C and Ali, RR and Kinnon, C and Thrasher, AJ (2005) Update on treatment of human SCID-X1 by somatic gene therapy using a pseudotyped gammaretroviral vector. In: BSGT Manchester 2005.

Pearce, DJ and Simpson, C and Allen, K and Eddaoudi, A and Davies, D and Bonnet, D (2005) Change in SP distribution with age reflects intrinsic age-based changes in stem cell biology: Implications for the mechanism of aging. In: BLOOD. (pp. 133B - 133B). AMER SOC HEMATOLOGY

Pearce, DJ and Taussig, D and Eddaoudi, A and Bonnet, D (2005) Age-dependent changes in hematopoietic stem and progenitor cells. In: EXPERIMENTAL HEMATOLOGY. (pp. 90 - 90). ELSEVIER SCIENCE INC

Plunkett, FJ and Franzese, O and Belaramani, LL and Fletcher, JM and Gilmour, KC and Sharifi, R and Khan, N and Hislop, AD and Cara, A and Salmon, M and Gaspar, HB and Rustin, MHA and Webster, D and Akbar, AN (2005) The impact of telomere erosion on memory CD8(+) T cells in patients with X-linked lymphoproliferative syndrome. MECH AGEING DEV , 126 (8) 855 - 865. 10.1016/j.mad.2005.03.006.

Q

Qasim, W and Gaspar, HB and Thrasher, AJ (2005) T cell suicide gene therapy to aid haematopoietic stem cell transplantation. CURR GENE THER , 5 (1) 121 - 132.

R

Raia, V and Maiuri, L and Ciacci, C and Ricciardelli, I and Vacca, L and Auricchio, S and Cimmino, M and Cavaliere, M and Nardone, M and Cesaro, A and Malcolm, J and Quaratino, S and Londei, M (2005) Inhibition of p38 mitogen activated protein kinase controls airway inflammation in cystic fibrosis. THORAX , 60 (9) 773 - 780. 10.1136/thx.2005.042564.

Rao, K and Amrolia, PJ and Jones, A and Cale, CM and Naik, P and King, D and Davies, GE and Gaspar, HB and Veys, PA (2005) Improved survival after unrelated donor bone marrow transplantation in children with primary immunodeficiency using a reduced-intensity conditioning regimen. Blood , 105 (2) 879 - 885. 10.1182/blood-2004-03-0960.

Ricciardelli, I and Maiuri, L and Quaratino, S and Londei, M (2005) Rho involvement in gliadin induced actin reorganization, tyrosine phosphorylation and apoptosis in coeliac disease (CD). IMMUNOLOGY , 116 84 - 84.

S

Santilli, G and Schwab, R and Watson, R and Ebert, C and Aronow, BJ and Sala, A (2005) Temperature-dependent modification and activation of B-MYB - Implications for cell survival. J BIOL CHEM , 280 (16) 15628 - 15634. 10.1074/jbc.M411747200.
An open access publication

Sarkar, S and Lee, LK and Hart, SL and Hailes, HC and Levy, SM and Tabor, A and Shamlou, PA (2005) The fractal structure of polycation-DNA complexes. BIOTECHNOL APPL BIOC , 41 127 - 136.

Schoggins, JW and Nociari, M and Philpott, N and Falck-Pedersen, E (2005) Influence of fiber detargeting on adenovirus-mediated innate and adaptive immune activation. Journal of Virology , 79 (18) 11627 - 11637.

Siapati, EK and Bigger, BW and Miskin, J and Chipchase, D and Parsley, KL and Mitrophanous, K and Themis, M and Thrasher, AJ and Bonnet, D (2005) Comparison of HIV- and EIAV-based vectors on their efficiency in transducing murine and human hematopoietic repopulating cells. Molecular Therapy , 12 (3) 537 - 546.

Smith, C.L. and Anthony, S. and Hubank, M. and Leiper, J.M. and Vallance, P. (2005) Effects of ADMA upon gene expression: an insight into the pathophysiological significance of raised plasma ADMA. PLoS Medicine , 2 (10) e264. 10.1371/journal.pmed.0020264.
An open access publication. A version is also available from UCL Discovery.
file

Spencer, H and Rampling, D and Aurora, P and Bonnet, D and Hart, SL and Jaffe, A (2005) Transbronchial biopsies provide longitudinal evidence for epithelial chimerism in children following sex mismatched lung transplantation. THORAX , 60 (1) 60 - 62. 10.1136/thx.2004.029678.
An open access version is available from UCL Discovery
file

T

Tagalakis, AD and Diakonov, IA and Graham, IR and Heald, KA and Harris, JD and Mulcahy, JV and Dickson, G and Owen, JS (2005) Apolipoprotein E delivery by peritoneal implantation of encapsulated recombinant cells improves the hyperlipidaemic profile in apoE-deficient mice. BBA-MOL CELL BIOL L , 1686 (3) 190 - 199. 10.1016/j.bbalip.2004.10.001.
An open access version is available from UCL Discovery
file

Tagalakis, AD and Dickson, JG and Owen, JS and Simons, JP (2005) Correction of the neuropathogenic human apolipoprotein E4 (APOE4) gene to APOE3 in vitro using synthetic RNA/DNA oligonucleotides (chimeraplasts). J Mol Neurosci , 25 (1) 95 - 103. 10.1385/JMN:25:1:095.

Tagalakis, AD and Owen, JS and Simons, JP (2005) Lack of RNA-DNA oligonucleotide (chimeraplast) mutagenic activity in mouse embryos. MOL REPROD DEV , 71 (2) 140 - 144. 10.1002/mrd.20250.
An open access version is available from UCL Discovery
file

Themis, M and Waddington, SN and Schmidt, M and Von Kalle, C and Wang, YH and Al Allaf, F and Gregory, LG and Nivsarkar, M and Themis, M and Holder, MV and Buckley, SMK and Dighe, N and Ruthe, AT and Mistry, A and Bigger, B and Rahim, A and Nguyen, TH and Trono, D and Thrasher, AJ and Coutelle, C (2005) Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice. Molecular Therapy , 12 (4) 763 - 771.

Themis, M and Waddington, SN and Schmidt, M and von Kalle, C and Wang, YH and Al-Allaf, F and Gregory, LG and Nivsarkar, M and Themis, M and Holder, MV and Buckley, SMK and Dighe, N and Ruthe, AT and Mistry, A and Bigger, B and Rahim, A and Nguyen, TH and Trono, D and Thrasher, AJ and Coutelle, C (2005) Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice. MOL THER , 12 (4) 763 - 771. 10.1016/j.ymthe.2005.07.358.

Thrasher, AJ (2005) Gene therapy: Great expectations? Medical Journal of Australia , 182 (9) 440 - 441.

Thrasher, AJ (2005) Update on treatment of human SLID by somatic gene therapy. Toxicology , 213 (3) 199 - 199.

Thrasher, AJ and Gaspar, HB (2005) Gene therapy for lympho-hematopoietic disorders. Curr Hematol Rep , 4 (4) 305 - 309.

Thrasher, AJ and Gaspar, HB (2005) Gene therapy in primary immunodeficiencies. Expert Rev Clin Immunol , 1 (2) 239 - 245. 10.1586/1744666X.1.2.239.

Thrasher, AJ and Hacein-Bey-Abina, S and Gaspar, HB and Blanche, S and Davies, EG and Parsley, K and Gilmour, K and King, D and Howe, S and Sinclair, J and Hue, C and Carlier, F and von Kalle, C and de Saint Basile, G and le Deist, F and Fischer, A and Cavazzana-Calvo, M (2005) Failure of SCID-X1 gene therapy in older patients. Blood , 105 (11) 4255 - 4257. 10.1182/blood-2004-12-4837.

Tiberio, M and Chard, DT and Altmann, DR and Davies, G and Griffin, CM and Rashid, W and Sastre-Garriga, J and Thompson, AJ and Miller, DH (2005) Gray and white matter volume changes in early RRMS - A 2-year longitudinal study. NEUROLOGY , 64 (6) 1001 - 1007.

Titman, PS and Morton, L and Skucek, E and Melvin, D and Gaspar, J and Jones, AM and Davies, EG and Thrasher, AJ and Gaspar, HB (2005) Cognitive and behavioural outcome following haematopoietic cell transplantation for severe congenital immunodeficiencies. Bone Marrow Transplantation , 35 S277 - S278.

Tschernutter, M and Schlichtenbrede, FC and Howe, S and Balaggan, KS and Munro, PM and Bainbridge, JWB and Thrasher, AJ and Smith, AJ and Ali, RR (2005) Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy. GENE THER , 12 (8) 694 - 701. 10.1038/sj.gt.3302460.

V

Veys, P and Rao, K and Amrolia, P (2005) Stem cell transplantation for congenital immunodeficiencies using reduced-intensity conditioning. Bone Marrow Transplant , 35 Suppl 1 S45 - S47. 10.1038/sj.bmt.1704846.

W

Westerberg, L and Larsson, M and Hardy, SJ and Fernandez, C and Thrasher, AJ and Severinson, E (2005) Wiskott-Aldrich syndrome protein deficiency leads to reduced B-cell adhesion, migration, and homing, and a delayed humoral immune response. BLOOD , 105 (3) 1144 - 1152. 10.1182/blood-2004-03-1003.

Williams, AP and Hourihane, JOB and Hodges, E and Gaspar, HB and Smith, J (2005) Multisystem disease in CAEBV infection. Clinical Immunology , 115 S248 - S248.

Williams, AR and Hourihane, JOB and Hodges, E and Davies, G and Smith, J (2005) Isolated PCP infection in children-A systemic or specific immunodeficiency? Clinical Immunology , 115 S250 - S250.

Wong, JB and Writer, M and Irvine, S and Tabor, AB and Hart, SL and Hailes, HC (2005) Role of cationic lipids in a non-viral lipid/peptide/DNA (LID) delivery system. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. (pp. U549 - U550). AMER CHEMICAL SOC

X

Xue, S and Gao, L and Hart, D and Gillmore, R and Qasime, W and Thrasher, A and Uckert, W and Morris, E and Stauss, H (2005) Development of WT1-specific CTL for the treatment of human leukemia through TCR gene transfer. In: EXPERIMENTAL HEMATOLOGY. (pp. 55 - 55). ELSEVIER SCIENCE INC

Xue, SA and Gao, L and Hart, D and Gillmore, R and Qasim, W and Thrasher, A and Apperley, J and Engels, B and Uckert, W and Morris, E and Stauss, H (2005) Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene-transduced human T cells. Blood , 106 (9) 3062 - 3067. 10.1182/blood-2005-01-0146.

Xue, SA and Gao, LQ and Hart, D and Gillmore, R and Qasim, W and Thrasher, A and Apperley, J and Engels, B and Uckert, W and Morris, E and Stauss, H (2005) Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene-transduced human T cells. BLOOD , 106 (9) 3062 - 3067. 10.1182/blood-2005-01-0146.

Y

Yanez, RJ and Balaggan, KS and Smith, AJ and Buch, P and Howe, S and MacNeilA, D and Y, A and P N, K and C, A and R R, T and A, J (2005) Effective Gene Therapy with Non-Integrating Lentiviral Vectors. In: BSGT Manchester 2005.

Yeung, J and Ellu, J and O'Sullivan, E and Ramanujachar, R and Brady, HJM (2005) Identification of E2A-HLF candidate target genes and their contribution to leukaemogenesis. In: BRITISH JOURNAL OF HAEMATOLOGY. (pp. 5 - 5). BLACKWELL PUBLISHING

This list was generated on Sun May 19 08:02:45 2013 BST.