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Number of items: 50.

A

Ankli, A and Heilmann, J and Heinrich, M and Sticher, O (2000) Cytotoxic cardenolides and antibacterial terpenoids from Crossopetalum gaumeri. PHYTOCHEMISTRY , 54 (5) 531 - 537. 10.1016/S0031-9422(00)00144-8.

B

Bennett, M and Krah, A and Wien, F and Garman, E and McKenna, R and Sanderson, M and Neidle, S (2000) A DNA-porphyrin minor-groove complex at atomic resolution: the structural consequences of porphyrin ruffling. Proc Natl Acad Sci U S A , 97 (17) 9476 - 9481. 10.1073/pnas.160271897.

Brickley, K and Sharma, S and Wilkinson, H and Stephenson, FA (2000) Characterisation of a novel protein found to interact with GABA-A receptors using the yeast two hybrid system. EUROPEAN JOURNAL OF NEUROSCIENCE , 12 42 - 42.

Brown, MD and Schätzlein, A and Brownlie, A and Jack, V and Wang, W and Tetley, L and Gray, AI and Uchegbu, IF (2000) Preliminary characterization of novel amino acid based polymeric vesicles as gene and drug delivery agents. Bioconjug Chem , 11 (6) 880 - 891.

Brownlie, A and Gray, AI and Schätzlein, AG and Tetley, L and Uchegbu, IF (2000) Polymeric vesicles from modified polyethylenimine polymers for gene delivery. Journal of Pharmacy and Pharmacology , 52 (9 SUPPL.) 56 - 56.

C

Caprio, V and Guyen, B and Opoku-Boahen, Y and Mann, J and Gowan, SM and Kelland, LM and Read, MA and Neidle, S (2000) A novel inhibitor of human telomerase derived from 10H-indolo[3,2-b]quinoline. Bioorg Med Chem Lett , 10 (18) 2063 - 2066.

Chopra, B and Chazot, PL and Stephenson, FA (2000) Characterization of the binding of two novel glycine site antagonists to cloned NMDA receptors: evidence for two pharmacological classes of antagonists. Br J Pharmacol , 130 (1) 65 - 72. 10.1038/sj.bjp.0703298.

D

Dufes, C and Schätzlein, AG and Tetley, L and Gray, AI and Watson, DG and Olivier, JC and Couet, W and Uchegbu, IF (2000) Niosomes and polymeric chitosan based vesicles bearing transferrin and glucose ligands for drug targeting. Pharm Res , 17 (10) 1250 - 1258.

E

Eatock, MM and Schätzlein, A and Kaye, SB (2000) Tumour vasculature as a target for anticancer therapy. Cancer Treat Rev , 26 (3) 191 - 204. 10.1053/ctrv.1999.0158.

F

Frei, B and Sticher, O and Heinrich, M (2000) Zapotec and Mixe use of tropical habitats for securing medicinal plants in Mexico. ECONOMIC BOTANY , 54 (1) 73 - 81. 10.1007/BF02866601.

Fujiyama, F and Fritschy, JM and Stephenson, FA and Bolam, JP (2000) Synaptic localization of GABA(A) receptor subunits in the striatum of the rat. JOURNAL OF COMPARATIVE NEUROLOGY , 416 (2) 158 - 172. 10.1002/(SICI)1096-9861(20000110)416:2<158::AID-CNE3>3.0.CO;2-L.

Fujiyama, F and Fritschy, JM and Stephenson, FA and Bolam, JP (2000) Synaptic localization of GABAA receptor subunits in the striatum of the rat. Journal of Comparative Neurology , 416 (2) 158 - 172. 10.1002/(SICI)1096-9861(20000110)416:2<158::AID-CNE3>3.0.CO;2-L.

G

Gibbons, S and Denny, BJ and Ali-Amine, S and Mathew, KT and Skelton, BW and White, AH and Gray, AI (2000) NMR spectroscopy, X-ray crystallographic, and molecular modeling studies on a new pyranone from Haloxylon salicornicum. J Nat Prod , 63 (6) 839 - 840.

Gibbons, S and Udo, EE (2000) The effect of reserpine, a modulator of multidrug efflux pumps, on the in vitro activity of tetracycline against clinical isolates of methicillin resistant Staphylococcus aureus (MRSA) possessing the tet(K) determinant. Phytother Res , 14 (2) 139 - 140.

H

Hawkins, LM and Chazot, PL and Stephenson, FA (2000) Using epitope-tagged subunits to determine the NR1 : NR2 subunit ratio of NMDA receptors. EUROPEAN JOURNAL OF NEUROSCIENCE , 12 37 - 37.

Heinrich, M (2000) Ethnobotany and ethnopharmacology: Their role in future medicinal plant research. Journal of Pharmacy and Pharmacology , 52 (9)

Heinrich, M (2000) Ethnobotany and its role in drug development. Phytother Res , 14 (7) 479 - 488.

Heinrich, M and Wickel, M and Schneider-Brachert, W and Sandberg, C and Gahr, J and Schwandner, R and Weber, T and Brunner, J and Kr�nke, M and Sch�tze, S (2000) Cathepsin D targeted by acid sphingomyelinase-derived ceramide. EMBO Journal , 19 (2) 10.1038/sj.emboj.7592140.

Heinrich, M and Wickel, M and Winoto-Morbach, S and Schneider-Brachert, W and Weber, T and Brunner, J and Saftig, P and Petersen, CC and Kr�nke, M and Sch�tze, S (2000) Ceramide as an activator lipid of cathepsin D. Advances in Experimental Medicine and Biology , 477 305 - 315.

Herget, T and Esdar, C and Oehrlein, SA and Heinrich, M and Sch�tze, S and Maelicke, A and van Echten-Deckert, G (2000) Production of ceramides causes apoptosis during early neural differentiation in vitro. Journal of Biological Chemistry , 275 (39) 30344 - 30354. 10.1074/jbc.M000714200.
An open access publication

Hilton, ST and Ho, TC and Pljevaljcic, G and Jones, K (2000) A new route to spirooxindoles. Org Lett , 2 (17) 2639 - 2641.

J

Johansson, E and Parkinson, G and Neidle, S (2000) A new crystal form for the dodecamer C-G-C-G-A-A-T-T-C-G-C-G: symmetry effects on sequence-dependent DNA structure. J Mol Biol , 300 (3) 551 - 561. 10.1006/jmbi.2000.3907.

K

Knight, AR and Stephenson, FA and Tallman, JF and Ramabahdran, TV (2000) Monospecific antibodies as probes for the stoichiometry of recombinant GABAA receptors. Receptors and Channels , 7 (3) 213 - 226.

L

Lin, FL and Majumdar, A and Klotz, LC and Reszka, AP and Neidle, S and Seidman, MM (2000) Stability of DNA triplexes on shuttle vector plasmids in the replication pool in mammalian cells. J Biol Chem , 275 (50) 39117 - 39124. 10.1074/jbc.M005404200.
An open access publication

M

Malkinson, JP and Falconer, RA and Toth, I (2000) Synthesis of C-terminal glycopeptides from resin-bound glycosyl azides via a modified Staudinger reaction. J Org Chem , 65 (17) 5249 - 5252.

Malkinson, JP and Keri, G and Artursson, P and Toth, I (2000) Novel lipoamino acid and liposaccharide based peptide delivery system for tumor selective somatostatin analogs. In: PEPTIDES FOR THE NEW MILLENNIUM. (pp. 779 - 781).

Marriott, JH and Moreno Barber, AM and Hardcastle, IR and Rowlands, MG and Grimshaw, RM and Neidle, S and Jarman, M (2000) Synthesis of the farnesyl ether 2,3,5-trifluoro-6-hydroxy-4-[(E,E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yloxy] nitrobenzene, and related compounds containing a substituted hydroxytrifluorophenyl residue: Novel inhibitors of protein farnesyltransferase, geranylgeranyltransferase I and squalene synthase. Journal of the Chemical Society, Perkin Transactions 1 (24) 4265 - 4278.

Mazur, S and Tanious, FA and Ding, D and Kumar, A and Boykin, DW and Simpson, IJ and Neidle, S and Wilson, WD (2000) A thermodynamic and structural analysis of DNA minor-groove complex formation. J Mol Biol , 300 (2) 321 - 337. 10.1006/jmbi.2000.3869.

N

Neidle, S and Harrison, RJ and Reszka, AP and Read, MA (2000) Structure-activity relationships among guanine-quadruplex telomerase inhibitors. Pharmacol Ther , 85 (3) 133 - 139.

Neidle, S and Read, MA (2000) G-quadruplexes as therapeutic targets. Biopolymers , 56 (3) 195 - 208. 10.1002/1097-0282(2000)56:3<195::AID-BIP10009>3.0.CO;2-5.

P

Parkinson, GN and Skelly, JV and Neidle, S (2000) Crystal structure of FMN-dependent nitroreductase from Escherichia coli B: a prodrug-activating enzyme. J Med Chem , 43 (20) 3624 - 3631.

R

Racca, C and Stephenson, FA and Streit, P and Roberts, JDB and Somogyi, P (2000) NMDA receptor content of synapses in stratum radiatum of the hippocampal CA1 area. JOURNAL OF NEUROSCIENCE , 20 (7) 2512 - 2522.

Read, MA and Neidle, S (2000) Structural characterization of a guanine-quadruplex ligand complex. Biochemistry , 39 (44) 13422 - 13432.

Rutter, AR and Stephenson, FA (2000) Coexpression of postsynaptic density-95 protein with NMDA receptors results in enhanced receptor expression together with a decreased sensitivity to L-glutamate. J Neurochem , 75 (6) 2501 - 2510.

Rutter, AR and Stephenson, FA (2000) Coexpression of PSD-95 with NR1/NR2A NMDA receptors decreases the enhancement of [3H]MK801 binding by glutamate. EUROPEAN JOURNAL OF NEUROSCIENCE , 12 465 - 465.

S

Sadiq, L and Gray, AI and Wang, W and Schätzlein, AG and Uchegbu, IF (2000) The solution properties of quaternary ammonium palmitoyl glycol chitosan - A new polysoap for drug delivery. Journal of Pharmacy and Pharmacology , 52 (9 SUPPL.) 35 - 35.

Sch�tze, S and Wickel, M and Heinrich, M and Winoto-Morbach, S and Weber, T and Brunner, J and Kr�nke, M (2000) Use of affinity chromatography and TID-ceramide photoaffinity labeling for detection of ceramide-binding proteins. Methods in Enzymology , 312 429 - 438. 10.1016/S0076-6879(00)12928-3.

Schlage, C and Mabula, C and Mahunnah, RLA and Heinrich, M (2000) Medicinal plants of the Washambaa (Tanzania): Documentation and ethnopharmacological evaluation. PLANT BIOLOGY , 2 (1) 83 - 92. 10.1055/s-2000-296.

Shah, DS and Sakthivel, T and Toth, I and Florence, AT and Wilderspin, AF (2000) DNA transfection and transfected cell viability using amphipathic asymmetric dendrimers. Int J Pharm , 208 (1-2) 41 - 48.

Sidhu, R and Clapham, JC and Wilderspin, AF (2000) Cloning and expression of cyclic nucleotide phosphodiesterase type 1 gene in E. coli. Journal of Pharmacy and Pharmacology , 52 (9 SUPPL.) 211 - 211.

Simpson, IJ and Lee, M and Kumar, A and Boykin, DW and Neidle, S (2000) DNA minor groove interactions and the biological activity of 2,5-bis-[4-(N-alkylamidino)phenyl] furans. Bioorganic and Medicinal Chemistry Letters , 10 (23) 2593 - 2597.

Simpson, IJ and Lee, M and Kumar, A and Boykin, DW and Neidle, S (2000) DNA minor groove interactions and the biological activity of 2,5-bis. Bioorg Med Chem Lett , 10 (23) 2593 - 2597.

Sludden, J and Uchegbu, IF and Schätzlein, AG (2000) The encapsulation of bleomycin within chitosan based polymeric vesicles does not alter its biodistribution. J Pharm Pharmacol , 52 (4) 377 - 382.

Stephenson, FA and Chopra, B and Chazot, PL and Hawkins, LM (2000) Radioligand binding studies indicate two pharmacological classes of glycine site antagonists active at the NMDA receptor. EUROPEAN JOURNAL OF NEUROSCIENCE , 12 464 - 464.

T

Thompson, CL and Drewery, DL and Atkins, HD and Stephenson, FA and Chazot, PL (2000) Immunohistochemical localization of N-methyl-D-aspartate receptor NR1, NR2A, NR2B and NR2C/D subunits in the adult mammalian cerebellum. NEUROSCIENCE LETTERS , 283 (2) 85 - 88. 10.1016/S0304-3940(00)00930-7.

Thompson, CL and Razzini, G and Pollard, S and Stephenson, FA (2000) Cyclic AMP-mediated regulation of GABA(A) receptor subunit expression in mature rat cerebellar granule cells: evidence for transcriptional and translational control. J Neurochem , 74 (3) 920 - 931.

W

Welham, KJ and Barrington, DH and Domin, MA and Heinrich, M (2000) High-performance liquid-chromatography mass spectrometry in the identification of active ingredients of St John's Wort herbal products. Journal of Pharmacy and Pharmacology , 52 (9 SUPPL.) 297 - 297.

Wells, G and Bradshaw, TD and Diana, P and Seaton, A and Shi, DF and Westwell, AD and Stevens, MF (2000) Antitumour benzothiazoles. Part 10: the synthesis and antitumour activity of benzothiazole substituted quinol derivatives. Bioorg Med Chem Lett , 10 (5) 513 - 515.

Wells, G and Seaton, A and Stevens, MF (2000) Structural studies on bioactive compounds. 32. Oxidation of tyrphostin protein tyrosine kinase inhibitors with hypervalent iodine reagents. J Med Chem , 43 (8) 1550 - 1562.

Z

Zloh, M and Esposito, D and Gibbons, WA (2000) Spectroscopy-based modelling of the 3D structure of the beta subunit of the high affinity IgE receptor. MOLECULAR SIMULATION , 24 (4-6) 421 - +. 10.1080/08927020008022386.

This list was generated on Fri May 24 06:44:52 2013 BST.