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Number of items: 77.

A

Appendino, G; Bianchi, F; Bader, A; Campagnuolo, C; Fattorusso, E; Taglialatela-Scafati, O; ... Munoz, E; + view all (2004) Coumarins from Opopanax chironium. New dihydrofuranocoumarins and differential induction of apoptosis by imperatorin and heraclenin. JOURNAL OF NATURAL PRODUCTS , 67 (4) 532 - 536. 10.1021/np0340652.

Appendino, G; Mercalli, E; Fuzzati, N; Arnoldi, L; Stavri, M; Gibbons, S; ... Maxia, A; + view all (2004) Antimycobacterial Coumarins from the Sardinian giant fennel (Ferula communis). JOURNAL OF NATURAL PRODUCTS , 67 (12) 2108 - 2110. 10.1021/np049706n.

B

Bailey, S; Fish, PV; James, K; McElroy, A; (2004) Discovery of UK-383,367, a potent and selective non-peptidic inhibitor of procollagen C-proteinase for the treatment of dermal scarring. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. (pp. U7 - U7).

Barber, CG; Dickinson, RP; Fish, PV; (2004) Selective urokinase-type plasminogen activator (uPA) inhibitors. Part 3: 1-isoquinolinylguanidines. Bioorg Med Chem Lett , 14 (12) 3227 - 3230. 10.1016/j.bmcl.2004.03.094.

Beha, E; Jung, A; Wiesner, J; Rimpler, H; Lanzer, M; Heinrich, M; (2004) Antimalarial activity of extracts of Abutilon grandiflorum G. Don - A traditional Tanzanian medicinal plant. PHYTOTHERAPY RESEARCH , 18 (3) 236 - 240. 10.1002/ptr.1393.

Braca, A; Prieto-Garcia, JM; De Tomassi, N; Tome, F; Morelli, I; (2004) Furostanol saponins and quercetin glycosides from the leaves of Helleborus viridis L. Phytochemistry , 65 (21) 2921 - 2928. 10.1016/j.phytochem.2004.07.013.

Bremner, P; Tang, S; Birkmayer, H; Fiebich, BL; Muñoz, E; Marquez, N; ... Heinrich, M; + view all (2004) Phenylpropanoid NF-kappaB inhibitors from Bupleurum fruticosum. Planta Med , 70 (10) 914 - 918. 10.1055/s-2004-832616.

Brier, S; Lemaire, D; Debonis, S; Forest, E; Kozielski, F; (2004) Identification of the protein binding region of S-trityl-L-cysteine, a new potent inhibitor of the mitotic kinesin Eg5. Biochemistry , 43 (41) 13072 - 13082. 10.1021/bi049264e.

Brownlie, A; Uchegbu, IF; Schätzlein, AG; (2004) PEI-based vesicle-polymer hybrid gene delivery system with improved biocompatibility. Int J Pharm , 274 (1-2) 41 - 52. 10.1016/j.ijpharm.2003.12.029.

C

Caceres, C; Wright, G; Gouyette, C; Parkinson, G; Subirana, JA; (2004) A thymine tetrad in d(TGGGGT) quadruplexes stabilized with Tl+/Na+ ions. NUCLEIC ACIDS RESEARCH , 32 (3) 1097 - 1102. 10.1093/nar/gkh269. Green and gold open access
file

Cassidy, J; Schätzlein, AG; (2004) Tumour-targeted drug and gene delivery: principles and concepts. Expert Rev Mol Med , 6 (19) 1 - 17. 10.1017/S1462399404008269.

D

DeBonis, S; Skoufias, DA; Lebeau, L; Lopez, R; Robin, G; Margolis, RL; ... Kozielski, F; + view all (2004) In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities. Mol Cancer Ther , 3 (9) 1079 - 1090.

Delazar, A; Byres, M; Gibbons, S; Kumarasamy, Y; Modarresi, M; Nahar, L; ... Sarker, SD; + view all (2004) Iridoid glycosides from Eremostachys glabra. J Nat Prod , 67 (9) 1584 - 1587. 10.1021/np040044b.

Denison, S; Hilton, ST; (2004) A Convenient Synthesis of 2-Cyano-3-Substituted Indoles. Synlett 2806 - 2808.

Denison, S; Hilton, ST; (2004) A convenient synthesis of 2-cyano-3-substituted indoles. SYNLETT (15) 2806 - 2808.

Dufes, C; Gaillard, F; Uchegbu, IF; Schätzlein, AG; Olivier, JC; Muller, JM; (2004) Glucose-targeted niosomes deliver vasoactive intestinal peptide (VIP) to the brain. Int J Pharm , 285 (1-2) 77 - 85. 10.1016/j.ijpharm.2004.07.020.

Dufes, C; Muller, JM; Couet, W; Olivier, JC; Uchegbu, IF; Schätzlein, AG; (2004) Anticancer drug delivery with transferrin targeted polymeric chitosan vesicles. Pharm Res , 21 (1) 101 - 107.

E

Edwards, SE; McMillen, H; (2004) Data Collection and Management in Ethnopharmacology (workshop). Presented at: 9th International Congress of Ethnobiology, Canterbury, University of Kent.

G

Garcia-Saez, I; Blot, D; Kahn, R; Kozielski, F; (2004) Crystallization and preliminary crystallographic analysis of the motor domain of human kinetochore-associated protein CENP-E using an automated crystallization procedure. Acta Crystallogr D Biol Crystallogr , 60 (Pt 6) 1158 - 1160. 10.1107/S0907444904009564.

Garcia-Saez, I; Yen, T; Wade, RH; Kozielski, F; (2004) Crystal structure of the motor domain of the human kinetochore protein CENP-E. J Mol Biol , 340 (5) 1107 - 1116. 10.1016/j.jmb.2004.05.053.

Gibbons, S; (2004) Anti-staphylococcal plant natural products. NATURAL PRODUCT REPORTS , 21 (2) 263 - 277. 10.1039/b212695h.

Gibbons, S; Moser, E; Kaatz, GW; (2004) Catechin gallates inhibit multidrug resistance (MDR) in Staphylococcus aureus. Planta Med , 70 (12) 1240 - 1242. 10.1055/s-2004-835860.

Groc, L; Heine, M; Cognet, L; Brickley, K; Stephenson, FA; Lounis, B; Choquet, D; (2004) Differential activity-dependent regulation of the lateral mobilities of AMPA and NMDA receptors. NATURE NEUROSCIENCE , 7 (7) 695 - 696. 10.1038/nn1270.

Guyen, B; Schultes, CM; Hazel, P; Mann, J; Neidle, S; (2004) Synthesis and evaluation of analogues of 10H-indolo[3,2-b]quinoline as G-quadruplex stabilising ligands and potential inhibitors of the enzyme telomerase. Org Biomol Chem , 2 (7) 981 - 988. 10.1039/b316055f.

H

Harrison, RJ; Reszka, AP; Haider, SM; Romagnoli, B; Morrell, J; Read, MA; ... Neidle, S; + view all (2004) Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding. Bioorg Med Chem Lett , 14 (23) 5845 - 5849. 10.1016/j.bmcl.2004.09.037.

Hawkins, LM; Prybylowski, K; Chang, K; Moussan, C; Stephenson, FA; Wenthold, RJ; (2004) Export from the endoplasmic reticulum of assembled N-methyl-D-aspartic acid receptors is controlled by a motif in the C terminus of the NR2 subunit. JOURNAL OF BIOLOGICAL CHEMISTRY , 279 (28) 28903 - 28910. 10.1074/jbc.M402599200. Gold open access

Hazel, P; Huppert, J; Balasubramanian, S; Neidle, S; (2004) Loop-length-dependent folding of G-quadruplexes. J Am Chem Soc , 126 (50) 16405 - 16415. 10.1021/ja045154j.

Heinrich, M; (2004) Snowdrops: The heralds of spring and a modern drug for Alzheimer's disease. Pharmaceutical Journal , 273 (7330) 905 - 906.

Heinrich, M; (2004) The extra year is for integrating science and practice [4]. Pharmaceutical Journal , 273 (7307) 51 - 51.

Heinrich, M; Barnes, J; Gibbons, S; Williamson, EM; (2004) Fundamentals of Pharmacognosy and Phytotherapy. Churchill Livingstone: Edinburgh, UK.

Heinrich, M; Lee Teoh, H; (2004) Galanthamine from snowdrop--the development of a modern drug against Alzheimer's disease from local Caucasian knowledge. J Ethnopharmacol , 92 (2-3) 147 - 162. 10.1016/j.jep.2004.02.012.

Heinrich, M; Orth, A; (2004) Medical knowledge of the Maya (Heilwissen der Maya). ZDF: Mainz, Germany.

Hilton, ST; Motherwell, WB; Selwood, DL; (2004) An expedient entry into the alpha-mercaptodiketopiperazine nucleus. SYNLETT (14) 2609 - 2611. 10.1055/s-2004-834823.

Hollins, AJ; Benboubetra, M; Omidi, Y; Zinselmeyer, BH; Schatzlein, AG; Uchegbu, IF; Akhtar, S; (2004) Evaluation of generation 2 and 3 poly(propylenimine) dendrimers for the potential cellular delivery of antisense oligonucleotides targeting the epidermal growth factor receptor. Pharm Res , 21 (3) 458 - 466. 10.1023/B:PHAM.0000019300.04836.51.

I

Incles, CM; Schultes, CM; Kempski, H; Koehler, H; Kelland, LR; Neidle, S; (2004) A G-quadruplex telomere targeting agent produces p16-associated senescence and chromosomal fusions in human prostate cancer cells. Mol Cancer Ther , 3 (10) 1201 - 1206.

J

Jacobo-Herrera, N; Bremner, P; Leonti, M; Gupta, MP; Gibbons, S; Heinrich, M; (2004) Searching for anti-inflammatory properties in Witheringia solanaceae L'Her (Solancaeae). JOURNAL OF PHARMACY AND PHARMACOLOGY , 56 S5 - S5.

Jacquamet, L; Ohana, J; Joly, J; Borel, F; Pirocchi, M; Charrault, P; ... Ferrer, JL; + view all (2004) Automated analysis of vapor diffusion crystallization drops with an X-ray beam. Structure , 12 (7) 1219 - 1225. 10.1016/j.str.2004.04.019.

K

Kan, PL; Wong, D; Waigh, RD; Watson, DG; Gray, AI; Uchegbu, IF; ... McAllister, M; + view all (2004) Highly hydrophilic fused aggregates (microsponges) from a C12 spermine bolaamphiphile. Journal of Physical Chemistry B , 108 (24) 8129 - 8135. 10.1021/jp0372237.

L

Ladame, S; Schouten, JA; Stuart, J; Roldan, J; Neidle, S; Balasubramanian, S; (2004) Tetrapeptides induce selective recognition for G-quadruplexes when conjugated to a DNA-binding platform. ORGANIC & BIOMOLECULAR CHEMISTRY , 2 (20) 2925 - 2931. 10.1039/b409698c.

Lechner, D; Stavri, M; Oluwatuyi, M; Pereda-Miranda, R; Gibbons, S; (2004) The anti-staphylococcal activity of Angelica dahurica (Bai Zhi). Phytochemistry , 65 (3) 331 - 335.

Lirussi, D; Li, J; Prieto-Garcia, JM; Gennari, M; Buschiazzo, H; Rios, JL; Zaidenberg, A; (2004) Inhibition of Trypanosoma cruzi by plant extracts used in Chinese medicine. Fitoterapia , 75 (7-8) 718 - 723. 10.1016/j.fitote.2004.09.017.

M

Macho, A; Blanco-Molina, M; Spagliardi, P; Appendino, G; Bremner, P; Heinrich, M; ... Munoz, E; + view all (2004) Calcium ionophoretic and apoptotic effects of ferutinin in the human Jurkat T-cell line. BIOCHEMICAL PHARMACOLOGY , 68 (5) 875 - 883. 10.1016/j.bep.2004.05.016.

Malkinson, JP; (2004) Pharmacists are scientists and clinicians [5]. Pharmaceutical Journal , 273 (7309) 113 - 113.

Malkinson, JP; Falconer, RA; (2004) Solid-phase synthesis of C-terminal thio-linked glycopeptides. In: Peptide Revolution: Genomics, Proteomics & Therapeutics. (pp. 73 - 74).

Malkinson, JP; Searcey, M; (2004) Solid-phase synthesis of des-N-tetramethyl triostin A (TANDEM). In: Peptide Revolution: Genomics, Proteomics & Therapeutics. (pp. 53 - 54).

Mallena, S; Lee, MP; Bailly, C; Neidle, S; Kumar, A; Boykin, DW; Wilson, WD; (2004) Thiophene-based diamidine forms a "super" at binding minor groove agent. J Am Chem Soc , 126 (42) 13659 - 13669. 10.1021/ja048175m.

Marquez, N; Sancho, R; Ballero, M; Bremner, P; Appendino, G; Fiebich, BL; ... Munoz, E; + view all (2004) Imperatorin inhibits T-cell proliferation by targeting the transcription factor NFAT. PLANTA MEDICA , 70 (11) 1016 - 1021. 10.1055/s-2004-832640.

N

Neidle, S; (2004) Stephen Neidle on cancer therapy and G-quadruplex inhibitors. Interview by Joanna De Souza. Drug Discov Today , 9 (18) 778 - 781. 10.1016/S1359-6446(04)03214-3.

Neidle, S; (2004) There's more to chemistry [4]. Chemistry World , 1 (4) 22 - 23.

Nguyen, B; Hamelberg, D; Bailly, C; Colson, P; Stanek, J; Brun, R; ... Wilson, WD; + view all (2004) Characterization of a novel DNA minor-groove complex. Biophys J , 86 (2) 1028 - 1041.

Nisar, S; Lane, CS; Wilderspin, AF; Welham, KJ; Griffiths, WJ; Patterson, LH; (2004) A proteomic approach to the identification of cytochrome P450 isoforms in male and female rat liver by nanoscale liquid chromatography-electrospray ionization-tandem mass spectrometry. Drug Metab Dispos , 32 (4) 382 - 386. 10.1124/dmd.32.4.382.

O

Ohnmacht, SA; Brenstrum, T; Bleicher, KH; McNulty, J; Capretta, A; (2004) Solid-phase Suzuki cross-coupling reactions using a phosphine ligand based on a phospha-adamantane framework. Tetrahedron Letters , 45 (29) 5661 - 5663. 10.1016/j.tetlet.2004.05.110.

Oluwatuyi, M; Kaatz, GW; Gibbons, S; (2004) Antibacterial and resistance modifying activity of Rosmarinus officinalis. Phytochemistry , 65 (24) 3249 - 3254. 10.1016/j.phytochem.2004.10.009.

P

Papadakis, M; Hawkins, LM; Stephenson, FA; (2004) Appropriate NR1-NR1 disulfide-linked homodimer formation is requisite for efficient expression of functional, cell surface N-methyl-D-aspartate NR1/NR2 receptors. J Biol Chem , 279 (15) 14703 - 14712. 10.1074/jbc.M313446200. Gold open access

Peran, M; Hooper, H; Rayner, SL; Stephenson, FA; Salas, R; (2004) GABA(A) receptor alpha 1 and alpha 6 subunits mediate cell surface anchoring in cultured cells. NEUROSCIENCE LETTERS , 364 (2) 67 - 70. 10.1016/j.neulet.2004.03.081.

Prieto-Garcia, JM; Giner, RM; Recio, MC; Manez, S; Rios, JL; (2004) Dual inhibition of cyclooxygenase-1 and 5-lipoxygenase by aerial part of Bupleurum fruticescens methanol extract. Fitoterapia , 75 (2) 179 - 186. 10.1016/j.fitote.2003.12.004.

Prieto-Garcia, JM; Recio, MC; Giner, RM; Manez, S; Giner-Larza, EM; Rios, JL; (2004) Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions. Journal of Pharmacy and Pharmacology , 55 (9) 1275 - 1282. 10.1211/0022357021620.

S

Schätzlein, AG; (2004) Introduction to therapeutic nucleic acids. In: Mahato, R, (ed.) Biomaterials-Based Delivery and Biocompatibility of Proteins and Nucleic Acids. (531 - 568). CRC Press: Boca Raton.

Schneider, I; Gibbons, S; Bucar, F; (2004) Inhibitory activity of Juniperus communis on 12(S)-HETE production in human platelets. PLANTA MEDICA , 70 (5) 471 - 474. 10.1055/s-2004-818980.

Schneider, I; Gibbons, S; Bucar, F; (2004) Medicinal plants with inhibitory activity on 12(S)-HETE production in human platelets. Planta Medica , 70 (5) 471 - 474.

Schultes, CM; Guyen, B; Cuesta, J; Neidle, S; (2004) Synthesis, biophysical and biological evaluation of 3,6-bis-amidoacridines with extended 9-anilino substituents as potent G-quadruplex-binding telomerase inhibitors. Bioorg Med Chem Lett , 14 (16) 4347 - 4351. 10.1016/j.bmcl.2004.05.090.

Simonsen, HT; Adsersen, A; Bremner, P; Heinrich, M; Smitt, UW; Jaroszewski, JW; (2004) Antifungal constituents of Melicope borbonica. PHYTOTHERAPY RESEARCH , 18 (7) 542 - 545. 10.1002/ptr.1482.

Smith, ECJ; Williamson, EM; Gibbons, S; (2004) The anti-staphylococcal activity of Chamaecyparis terpenoids. JOURNAL OF PHARMACY AND PHARMACOLOGY , 56 S81 - S81.

Smyth, R; Turton, JA; Clarke, CJ; York, MJ; Dare, TO; Lane, CS; ... Munday, MR; + view all (2004) The identification of superoxide dismutase in rat urine following carbon tetrachloride-induced hepatotoxicity. In: TOXICOLOGY. (pp. 271 - 272).

Stapleton, P; Adams, V; Pike, R; Lucas, V; Roberts, G; Mullany, P; ... Richards, H; + view all (2004) Characterisation of viridans group streptococci with different levels of Tet(M)-mediated tetracycline resistance. INT J ANTIMICROB AG , 24 (5) 439 - 443. 10.1016/j.ijantimicag.2004.06.003.

Stapleton, P; Pike, R; Mullany, P; Lucas, V; Roberts, G; Rowbury, R; ... Richards, H; + view all (2004) Mercuric resistance genes in gram-positive oral bacteria. FEMS MICROBIOL LETT , 236 (2) 213 - 220. 10.1016/j.femsle.2004.05.041.

Stapleton, PD; Shah, S; Anderson, JC; Hara, Y; Hamilton-Miller, JMT; Taylor, PW; (2004) Modulation of beta-lactam resistance in Staphylococcus aureus by catechins and gallates. INT J ANTIMICROB AG , 23 (5) 462 - 467. 10.1016/j.ijantimicag.2003.09.027.

Stapleton, PD; Shah, S; Anderson, JC; Hara, Y; Hamilton-Miller, JMT; Taylor, PW; (2004) Modulation of beta-lactam resistance in Staphylococcus aureus by catechins and gallates. International Journal of Antimicrobial Agents , 23 (5) 462 - 467. 10.1016/j.ijantimicag.2003.09.027.

Stapleton, PD; Shah, S; Hamilton-Miller, JMT; Hara, Y; Nagaoka, Y; Kumagai, A; ... Taylor, PW; + view all (2004) Anti-Staphylococcus aureus activity and oxacillin resistance modulating capacity of 3-O-acyl-catechins. INT J ANTIMICROB AG , 24 (4) 374 - 380. 10.1016/j.ijantimicag.2004.03.024.

Stavri, M; Mathew, KT; Gibson, T; Williamson, RT; Gibbons, S; (2004) New constituents of Artemisia monosperma. J Nat Prod , 67 (5) 892 - 894. 10.1021/np030558v.

Stavri, M; Schneider, R; O'Donnell, G; Lechner, D; Bucar, F; Gibbons, S; (2004) The antimycobacterial components of hops (Humulus lupulus) and their dereplication. Phytother Res , 18 (9) 774 - 776. 10.1002/ptr.1527.

T

Taylor, PW; Stapleton, PD; Shah, S; Anderson, JC; (2004) Modification of staphylococci by catechin gallates. ICOS Proceedings , 2 414 - 417.

U

Uchegbu, IF; (2004) Polymers in drug delivery. In: UNSPECIFIED (475 - 475).

Uchegbu, IF; Sadiq, L; Pardakhty, A; El-Hammadi, M; Gray, AI; Tetley, L; ... Schätzlein, AG; + view all (2004) Gene transfer with three amphiphilic glycol chitosans--the degree of polymerisation is the main controller of transfection efficiency. J Drug Target , 12 (8) 527 - 539. 10.1080/10611860400011943.

W

Werstuck, GH; Kim, AJ; Brenstrum, T; Ohnmacht, SA; Panna, E; Capretta, A; (2004) Examining the correlations between GSK-3 inhibitory properties and anti-convulsant efficacy of valproate and valproate-related compounds. Bioorganic & Medicinal Chemistry Letters , 14 (22) 5465 - 5467. 10.1016/j.bmcl.2004.09.013.

Z

Zloh, M; Gibbons, S; (2004) Molecular similarity of MDR inhibitors. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 5 (2) 37 - 47. 10.3390/i5020037. Green and gold open access
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Zloh, M; Kaatz, GW; Gibbons, S; (2004) Inhibitors of multidrug resistance (MDR) have affinity for MDR substrates. Bioorg Med Chem Lett , 14 (4) 881 - 885. 10.1016/j.bmcl.2003.12.015.

This list was generated on Sun Aug 24 09:38:10 2014 BST.