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Number of items: 77.

A

Appleton, K; Mackay, HJ; Judson, I; Plumb, JA; McCormick, C; Strathdee, G; ... Brown, R; + view all (2007) Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors. J Clin Oncol , 25 (29) 4603 - 4609. 10.1200/JCO.2007.10.8688.

Arola, A; Neidle, S; Reed, JE; Vilar, R; (2007) INOR 151-Stabilization of quadruplex DNA and inhibition of telomerase by square planar metal complexes. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY , 234

B

Bell, HS; Dufes, C; O'Prey, J; Crighton, D; Bergamaschi, D; Lu, X; ... Ryan, KM; + view all (2007) A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo. J CLIN INVEST , 117 (4) 1008 - 1018. 10.1172/JCI28920.

Bolam, DN; Roberts, S; Proctor, MR; Turkenburg, JP; Dodson, EJ; Martinez-Fleites, C; ... Gilbert, HJ; + view all (2007) The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , 104 (13) 5336 - 5341. 10.1073/pnas.0607897104.

CANCER RESEARCH TECHNOLOGY LIMITED, R. Brown, J. Plumb, G. W. Aherne, E. Mcdonald, K. Jones, S. Hilton (2007) Preparation of 2-[3H]-thiazol-2-ylidine-methylpyridine and related compounds and their use as antitumor agents. Green open access
file

C

Campbell, NH; Parkinson, GN; (2007) Crystallographic studies of quadruplex nucleic acids. Methods , 43 (4) 252 - 263. 10.1016/j.ymeth.2007.08.005.

D

Davies, RJH; Malone, JF; Gan, Y; Cardin, CJ; Lee, MPH; Neidle, S; (2007) High-resolution crystal structure of the intramolecular d(TpA) thymine-adenine photoadduct and its mechanistic implications. NUCLEIC ACIDS RESEARCH , 35 (4) 1048 - 1053. 10.1093/nar/gkl1101. Green and gold open access
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Dawson, S; Malkinson, JP; Paumier, D; Searcey, M; (2007) Bisintercalator natural products with potential therapeutic applications: isolation, structure determination, synthetic and biological studies. NAT PROD REP , 24 (1) 109 - 126. 10.1039/b516347c.

F

Fish, PV; Allan, GA; Bailey, S; Blagg, J; Butt, R; Collis, MG; ... Whitlock, GA; + view all (2007) Potent and selective nonpeptidic inhibitors of procollagen C-proteinase. J Med Chem , 50 (15) 3442 - 3456. 10.1021/jm061010z.

Fish, PV; Barber, CG; Brown, DG; Butt, R; Collis, MG; Dickinson, RP; ... Webster, R; + view all (2007) Selective urokinase-type plasminogen activator inhibitors. 4. 1-(7-sulfonamidoisoquinolinyl)guanidines. J Med Chem , 50 (10) 2341 - 2351. 10.1021/jm061066t.

Fish, PV; Fray, MJ; Stobie, A; Wakenhut, F; Whitlock, GA; (2007) N-Benzyl-N-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amines as selective dual serotonin/noradrenaline reuptake inhibitors. Bioorg Med Chem Lett , 17 (7) 2022 - 2025. 10.1016/j.bmcl.2007.01.020.

Franklin, BD; Seedat, H; Heinrich, M; (2007) Use of herbal remedies by patients admitted to hospital. In: PHARMACY WORLD & SCIENCE. (pp. A243 - A244).

G

Gibbons, S; (2007) Phytochemicals for bacterial resistance - strengths, weaknesses and opportunities. In: PLANTA MEDICA. (pp. 798 - 798).

Groc, L; Choquet, D; Stephenson, FA; Verrier, D; Manzoni, OJ; Chavis, P; (2007) NMDA receptor surface trafficking and synaptic subunit composition are developmentally regulated by the extracellular matrix protein reelin. JOURNAL OF NEUROSCIENCE , 27 (38) 10165 - 10175. 10.1523/JNEUROSCI.1772-07.2007.

Gunaratnam, M; Cuenca, F; Beltran, M; Swank, S; Fletcher, J; Neidle, S; (2007) Targeting imatinib-resistant gastrointestinal stromal tumors by down-regulation of KIT gene expression with quadruplex-stabilizing small molecules. MOLECULAR CANCER THERAPEUTICS , 6 (12) 3519S - 3519S.

Gunaratnam, M; Greciano, O; Martins, C; Reszka, AP; Schultes, CM; Morjani, H; ... Neidle, S; + view all (2007) Mechanism of acridine-based telomerase inhibition and telomere shortening. Biochem Pharmacol , 74 (5) 679 - 689. 10.1016/j.bcp.2007.06.011.

Guo, X; Evans, TR; Somanath, S; Armesilla, AL; Darling, JL; Schatzlein, A; ... Wang, W; + view all (2007) In vitro evaluation of cancer-specific NF-kappaB-CEA enhancer-promoter system for 5-fluorouracil prodrug gene therapy in colon cancer cell lines. Br J Cancer , 97 (6) 745 - 754. 10.1038/sj.bjc.6603930.

H

Hadjivassileva, T; Stapleton, PD; Thurston, DE; Taylor, PW; (2007) Interactions of pyrrolobenzodiazepine dimers and duplex DNA from methicillin-resistant Staphylococcus aureus. Int J Antimicrob Agents , 29 (6) 672 - 678. 10.1016/j.ijantimicag.2007.01.005.

Harrison, CA; Bastan, R; Peirce, MJ; Munday, MR; Peachell, PT; (2007) Role of calcineurin in the regulation of human lung mast cell and basophil function by cyclosporine and FK506. BRITISH JOURNAL OF PHARMACOLOGY , 150 (4) 509 - 518. 10.1038/sj.bjp.0707002.

Heinrich, M; (2007) Herbal medicines in health care - Benefits and risks. In: TOXICOLOGY. (pp. 148 - 149).

Heinrich, M; Modarai, M; Kortenkamp, A; (2007) CYP inhibitory action of Echinacea preparations differs widely, but is it clinically relevant? In: PLANTA MEDICA. (pp. 823 - 823).

Heinrich, M; Modarai, M; Kortenkamp, A; (2007) Drug interactions with Echinacea: does it matter how the product is made? JOURNAL OF PHARMACY AND PHARMACOLOGY , 59 A80 - A80.

Heinrich, M; Nebel, S; Leonti, M; (2007) Local European medicinal and food plants - how can they contribute to improved health? In: Hamazaki, T and Nagasawa, T and Okuyama, H, (eds.) In what areas are traditional/alternative medicines useful? (121 - 131). Nakatani Printing: Toyama, Japan.

Hilton, ST; Jones, K; (2007) The tandem radical route to indole alkaloids: an unusual rearrangement reaction. ARKIVOC 120 - 128.

Hilton, ST; Jones, K; (2007) The tandem radical route to indole alkaloids: an unusual rearrangement reaction. Arkivoc , 2007 (XI) 120 - 128. Green and gold open access
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K

Ka Po Shiu, W; Gibbons, S; (2007) Isolation and characterization of a new dibenzofuran from Hypericum revolutum ssp revolutum Vahl. In: PLANTA MEDICA. (pp. 943 - 943).

Kokubun, T; Shiu, WKP; Gibbons, S; (2007) Inhibitory activities of lichen-derived compounds against methicillin- and multidrug-resistant Staphylococcus aureus. PLANTA MEDICA , 73 (2) 176 - 179. 10.1055/s-2006-957070.

L

Lechner, D; Gibbons, S; Bucar, F; (2007) Modulation of isoniazid susceptibility of mycobacterial strains by different flavonoids. In: PLANTA MEDICA. (pp. 848 - 848).

Lee, MP; Parkinson, GN; Hazel, P; Neidle, S; (2007) Observation of the coexistence of sodium and calcium ions in a DNA G-quadruplex ion channel. J Am Chem Soc , 129 (33) 10106 - 10107. 10.1021/ja0740869.

M

Martins, C; Gunaratnam, M; Stuart, J; Makwana, V; Greciano, O; Reszka, AP; ... Neidle, S; + view all (2007) Structure-based design of benzylamino-acridine compounds as G-quadruplex DNA telomere targeting agents. Bioorg Med Chem Lett , 17 (8) 2293 - 2298. 10.1016/j.bmcl.2007.01.056.

Michalet, S; Cartier, G; David, B; Mariotte, A-M; Dijoux-franca, M-G; Kaatz, GW; ... Gibbons, S; + view all (2007) N-Caffeoylphenalkylamide derivatives as bacterial efflux pump inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , 17 (6) 1755 - 1758. 10.1016/j.bmcl.2006.12.059.

Milroy, LG; Zinzalla, G; Prencipe, G; Michel, P; Ley, SV; Gunaratnam, M; ... Neidle, S; + view all (2007) Chemical variation of natural-product-like scaffolds: design, synthesis, and biological activity of fused bicyclic acetal derivatives. Angew Chem Int Ed Engl , 46 (14) 2493 - 2496. 10.1002/anie.200604688.

Modarai, M; Gertsch, J; Suter, A; Heinrich, M; Kortenkamp, A; (2007) Cytochrome P450 inhibitory action of Echinacea preparations differs widely and co-varies with alkylamide content. J Pharm Pharmacol , 59 (4) 567 - 573. 10.1211/jpp.59.4.0012.

Modarai, M; Wilson, N; Politi, M; Suter, A; Kortenkamp, A; Heinrich, M; (2007) Echinacea liquid formulations - NMR spectroscopy and multivariate data analysis of fractions with CYP3A4 inhibitory activity. JOURNAL OF PHARMACY AND PHARMACOLOGY , 59 A63 - A63.

Modarai, M; Wilson, N; Politi, M; Suter, A; Kortenkamp, A; Heinrich, M; (2007) Evaluating CYP3A4 inhibitory activity of Echinacea extracts using NMR and multivariate data analysis. In: PLANTA MEDICA. (pp. 990 - 991).

Munde, M; Lee, M; Neidle, S; Arafa, R; Boykin, DW; Liu, Y; ... Wilson, WD; + view all (2007) Induced fit conformational changes of a "reversed amidine" heterocycle: optimized interactions in a DNA minor groove complex. J Am Chem Soc , 129 (17) 5688 - 5698. 10.1021/ja069003n.

N

Neidle, S; (2007) Methods for studying quadruplex nucleic acids. Methods , 43 (4) 10.1016/j.ymeth.2007.10.001.

Neidle, S; (2007) Methods for studying quadruplex nucleic acids. METHODS , 43 (4) 245 - 245. 10.1016/j.ymeth.2007.10.001.

O

O'Donnell, G; Gibbons, S; (2007) Antibacterial activity of two canthin-6-one alkaloids from Allium neapolitanum. Phytother Res , 21 (7) 653 - 657. 10.1002/ptr.2136.

P

Palmer, AM; Stephenson, FA; Williams, RJ; (2007) Society for Medicines Research: 40th Anniversary Symposium. Drug News and Perspectives , 20 (3) 191 - 196.

Parkinson, GN; (2007) Nucleic acids research. In: Firm, OJ and Central, NIOHUSP and Press, H, (eds.) Nucleic acids research.

Parkinson, GN; Ghosh, R; Neidle, S; (2007) Structural basis for binding of porphyrin to human telomeres. Biochemistry , 46 (9) 2390 - 2397. 10.1021/bi062244n.

Peschel, W; Politi, M; Wilson, N; Constanti, A; Prieto, GJM; Heinrich, M; (2007) Cannabis tinctures and extracts - in vitro profiling for cytotoxic and anti-inflammatory effects. In: PLANTA MEDICA. (pp. 841 - 842).

Phan, AT; Kuryavyi, V; Burge, S; Neidle, S; Patel, DJ; (2007) Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter. J Am Chem Soc , 129 (14) 4386 - 4392. 10.1021/ja068739h.

Phan, AT; Kuryavyi, V; Burge, S; Neidle, S; Patel, DJ; (2007) The unprecedented structure of a G-quadruplex formed in the human c-kit promoter. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , 24 (6) 712 - 713.

Politi, M; Prieto, JM; Heinrich, M; (2007) Direct metabolic fingerprinting by NMR spectroscopy as a new method for the analysis of herbal tinctures. In: PLANTA MEDICA. (pp. 903 - 903).

Prieto, JM; Iacopini, P; Cioni, P; Chericoni, S; (2007) In vitro activity of the essential oils of Origanum vulgare, Satureja montana and their main constituents in peroxynitrite-induced oxidative processes. FOOD CHEMISTRY , 104 (3) 889 - 895. 10.1016/j.foodchem.2006.01.064.

Prieto-Garcia, JM; (2007) La regulacion global de los medicamentos herbarios. Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas , 6 (4) 92 - 101. Green and gold open access
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Prieto-Garcia, JM; Schaffner, U; Barker, A; Braca, A; Siciliano, T; Boeve, JL; (2007) Sequestration of furostanol saponins by Monophadnus sawfly larvae. Journal of Chemical Ecology , 33 (3) 513 - 524. 10.1007/s10886-006-9232-7.

R

Rahman, MM; Gibbons, S; (2007) The anti-staphylococcal activity of terpenes from Commiphora molmol Engl. In: PLANTA MEDICA. (pp. 872 - 872).

Rahman, MM; Gibbons, S; Gray, AI; (2007) Isoflavanones from Uraria picta and their antimicrobial activity. PHYTOCHEMISTRY , 68 (12) 1692 - 1697. 10.1016/j.phytochem.2007.04.015.

Reed, JE; Neidle, S; Vilar, R; (2007) Stabilisation of human telomeric quadruplex DNA and inhibition of telomerase by a platinum-phenanthroline complex. Chem Commun (Camb) (42) 4366 - 4368. 10.1039/b709898g.

Reed, JE; Neidle, S; Vilar, R; (2007) Stabilisation of human telomeric quadruplex DNA and inhibition of telomerase by a platinum?phenanthroline complex. Chemical Communications (42) 4366 - 4368. 10.1039/b709898g.

Rivera, D; Obon, C; Inocencio, C; Heinrich, M; Verde, A; Fajardo, J; Palazon, JA; (2007) Gathered food plants in the mountains of Castilla-La mancha (Spain): Ethnobotany and Multivariate analysis. ECONOMIC BOTANY , 61 (3) 269 - 289. 10.1663/0013-0001(2007)61[269:GFPITM]2.0.CO;2.

Robins, RJ; Gibbons, S; Marston, A; (2007) The fiftieth anniversary meeting of the Phytochemical Society of Europe: Churchill College, Cambridge, 11-14 April 2007 Highlights in the Evolution of Phytochemistry. PHYTOCHEMISTRY , 68 (22-24) 2699 - 2704. 10.1016/j.phytochem.2007.10.003.

S

Schrettl, M; Bignell, E; Kragl, C; Sabiha, Y; Loss, O; Eisendle, M; ... Haas, H; + view all (2007) Distinct Roles for Intra- and Extracellular Siderophores during Aspergillus fumigatus Infection. PLoS Pathogens , 3 (9) e128 - e128. 10.1371/journal.ppat.0030128. Gold open access

Shiu, KP; Gibbons, S; (2007) The anti-staphylococcal activity of Hypericum species. In: PLANTA MEDICA. (pp. 872 - 873).

Smith, E; Gibbons, S; (2007) 2 beta-acetoxyferruginol - a new antibacterial abietane diterpene from Prumnopitys andina. In: PLANTA MEDICA. (pp. 807 - 807).

Smith, E; Gibbons, S; (2007) Myrceocommunic acid - a labdane diterpene with activity against Staphylococcus aureus and Propionibacterium acnes. In: PLANTA MEDICA. (pp. 944 - 944).

Smith, EC; Kaatz, GW; Seo, SM; Wareham, N; Williamson, EM; Gibbons, S; (2007) The phenolic diterpene totarol inhibits multidrug efflux pump activity in Staphylococcus aureus. Antimicrob Agents Chemother , 51 (12) 4480 - 4483. 10.1128/AAC.00216-07.

Smith, EC; Williamson, EM; Wareham, N; Kaatz, GW; Gibbons, S; (2007) Antibacterials and modulators of bacterial resistance from the immature cones of Chamaecyparis lawsoniana. Phytochemistry , 68 (2) 210 - 217. 10.1016/j.phytochem.2006.10.001.

Smyth, R; Munday, MR; York, MJ; Clarke, CJ; Dare, T; Turton, JA; (2007) Comprehensive characterization of serum clinical chemistry parameters and the identification of urinary superoxide dismutase in a carbon tetrachloride-induced model of hepatic fibrosis in the female Hanover Wistar rat. Int J Exp Pathol , 88 (5) 361 - 376. 10.1111/j.1365-2613.2007.00543.x.

Stapleton, PD; Shah, S; Ehlert, K; Hara, Y; Taylor, PW; (2007) The beta-lactam-resistance modifier (-)-epicatechin gallate alters the architecture of the cell wall of Staphylococcus aureus. Microbiology , 153 (Pt 7) 2093 - 2103. 10.1099/mic.0.2007/007807-0.

Stavri, M; Gibbons, S; (2007) Antibacterial constituents from Plectranthus ciliatus. In: PLANTA MEDICA. (pp. 873 - 873).

Stavri, M; Gibbons, S; (2007) New diterpenes from Plectranthus emstii. In: PLANTA MEDICA. (pp. 873 - 873).

Stavri, M; Piddock, LJ; Gibbons, S; (2007) Bacterial efflux pump inhibitors from natural sources. J Antimicrob Chemother , 59 (6) 1247 - 1260. 10.1093/jac/dkl460.

T

Todd, AK; Haider, SM; Parkinson, GN; Neidle, S; (2007) Sequence occurrence and structural uniqueness of a G-quadruplex in the human c-kit promoter. Nucleic Acids Res , 35 (17) 5799 - 5808. 10.1093/nar/gkm609. Green and gold open access
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U

Uddin, SJ; Nahar, L; Shilpi, JA; Shoeb, M; Borkowski, T; Gibbons, S; ... Sarker, SD; + view all (2007) Gedunin, a limonoid from Xylocarpus granatum, inhibits the growth of CaCo-2 colon cancer cell line in vitro. PHYTOTHERAPY RESEARCH , 21 (8) 757 - 761. 10.1002/ptr.2159.

W

White, EW; Tanious, F; Ismail, MA; Reszka, AP; Neidle, S; Boykin, DW; Wilson, WD; (2007) Structure-specific recognition of quadruplex DNA by organic cations: Influence of shape, substituents and charge. BIOPHYSICAL CHEMISTRY , 126 (1-3) 140 - 153. 10.1016/j.bpc.2006.06.006.

White, EW; Tanious, F; Ismail, MA; Reszka, AP; Neidle, S; Boykin, DW; Wilson, WD; (2007) Structure-specific recognition of quadruplex DNA by organic cations: influence of shape, substituents and charge. Biophys Chem , 126 (1-3) 140 - 153. 10.1016/j.bpc.2006.06.006.

Whitlock, GA; Wakenhut, F; Stobie, A; Fish, PV; Fray, MJ; (2007) Discovery of PF-184298, a dual serotonin/noradrenaline reuptake inhibitor. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY , 233 590 - 590.

Woon, EC; Arcieri, M; Wilderspin, AF; Malkinson, JP; Searcey, M; (2007) Solid-phase synthesis of chlorofusin analogues. J Org Chem , 72 (14) 5146 - 5151. 10.1021/jo070450a.

X

Xiao, ZY; Mu, Q; Shiu, WK; Zeng, YH; Gibbons, S; (2007) Polyisoprenylated benzoylphloroglucinol derivatives from Hypericum sampsonii. J Nat Prod , 70 (11) 1779 - 1782. 10.1021/np0704147.

Y

Yang, M; Davies, GJ; Davis, BG; (2007) A glycosynthase catalyst for the synthesis of flavonoid glycosides. Angew Chem Int Ed Engl , 46 (21) 3885 - 3888. 10.1002/anie.200604177.

Z

Zhao, YH; Abraham, MH; Ibrahim, A; Fish, PV; Cole, S; Lewis, ML; ... Reynolds, DP; + view all (2007) Predicting penetration across the blood-brain barrier from simple descriptors and fragmentation schemes. J Chem Inf Model , 47 (1) 170 - 175. 10.1021/ci600312d.

Zloh, M; Bucar, F; Gibbons, S; (2007) Quantum chemical studies on structure activity relationship of natural product polyacetylenes. THEORETICAL CHEMISTRY ACCOUNTS , 117 (2) 247 - 252. 10.1007/s00214-006-0148-7.

Zloh, M; Gibbons, S; (2007) The role of small molecule-small molecule interactions in overcoming biological barriers for antibacterial drug action. THEORETICAL CHEMISTRY ACCOUNTS , 117 (2) 231 - 238. 10.1007/s00214-006-0149-6.

This list was generated on Sun Apr 13 08:58:28 2014 BST.