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Number of items: 80.

A

Appleton, K and Mackay, HJ and Judson, I and Plumb, JA and McCormick, C and Strathdee, G and Lee, C and Barrett, S and Reade, S and Jadayel, D and Tang, A and Bellenger, K and Mackay, L and Setanoians, A and Schätzlein, A and Twelves, C and Kaye, SB and Brown, R (2007) Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors. J Clin Oncol , 25 (29) 4603 - 4609. 10.1200/JCO.2007.10.8688.

Arola, A and Neidle, S and Reed, JE and Vilar, R (2007) INOR 151-Stabilization of quadruplex DNA and inhibition of telomerase by square planar metal complexes. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY , 234

B

Balan, S and Choi, JW and Godwin, A and Teo, I and Laborde, CM and Heidelberger, S and Zloh, M and Shaunak, S and Brocchini, S (2007) Site-specific PEGylation of protein disulfide bonds using a three-carbon bridge. Bioconjug Chem , 18 (1) 61 - 76. 10.1021/bc0601471.

Bell, HS and Dufes, C and O'Prey, J and Crighton, D and Bergamaschi, D and Lu, X and Schatzlein, AG and Vousden, KH and Ryan, KM (2007) A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo. J CLIN INVEST , 117 (4) 1008 - 1018. 10.1172/JCI28920.

Bolam, DN and Roberts, S and Proctor, MR and Turkenburg, JP and Dodson, EJ and Martinez-Fleites, C and Yang, M and Davis, BG and Davies, GJ and Gilbert, HJ (2007) The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , 104 (13) 5336 - 5341. 10.1073/pnas.0607897104.

CANCER RESEARCH TECHNOLOGY LIMITED, R. Brown, J. Plumb, G. W. Aherne, E. Mcdonald, K. Jones, S. Hilton (2007) Preparation of 2-[3H]-thiazol-2-ylidine-methylpyridine and related compounds and their use as antitumor agents.
An open access version is available from UCL Discovery
 file

C

Campbell, NH and Parkinson, GN (2007) Crystallographic studies of quadruplex nucleic acids. Methods , 43 (4) 252 - 263. 10.1016/j.ymeth.2007.08.005.

D

Davies, RJH and Malone, JF and Gan, Y and Cardin, CJ and Lee, MPH and Neidle, S (2007) High-resolution crystal structure of the intramolecular d(TpA) thymine-adenine photoadduct and its mechanistic implications. NUCLEIC ACIDS RESEARCH , 35 (4) 1048 - 1053. 10.1093/nar/gkl1101.
An open access publication. A version is also available from UCL Discovery.
 file

Dawson, S and Malkinson, JP and Paumier, D and Searcey, M (2007) Bisintercalator natural products with potential therapeutic applications: isolation, structure determination, synthetic and biological studies. NAT PROD REP , 24 (1) 109 - 126. 10.1039/b516347c.

F

Fish, PV and Allan, GA and Bailey, S and Blagg, J and Butt, R and Collis, MG and Greiling, D and James, K and Kendall, J and McElroy, A and McCleverty, D and Reed, C and Webster, R and Whitlock, GA (2007) Potent and selective nonpeptidic inhibitors of procollagen C-proteinase. J Med Chem , 50 (15) 3442 - 3456. 10.1021/jm061010z.

Fish, PV and Barber, CG and Brown, DG and Butt, R and Collis, MG and Dickinson, RP and Henry, BT and Horne, VA and Huggins, JP and King, E and O'Gara, M and McCleverty, D and McIntosh, F and Phillips, C and Webster, R (2007) Selective urokinase-type plasminogen activator inhibitors. 4. 1-(7-sulfonamidoisoquinolinyl)guanidines. J Med Chem , 50 (10) 2341 - 2351. 10.1021/jm061066t.

Fish, PV and Fray, MJ and Stobie, A and Wakenhut, F and Whitlock, GA (2007) N-Benzyl-N-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amines as selective dual serotonin/noradrenaline reuptake inhibitors. Bioorg Med Chem Lett , 17 (7) 2022 - 2025. 10.1016/j.bmcl.2007.01.020.

Franklin, BD and Seedat, H and Heinrich, M (2007) Use of herbal remedies by patients admitted to hospital. In: PHARMACY WORLD & SCIENCE. (pp. A243 - A244).

G

Gibbons, S (2007) Phytochemicals for bacterial resistance - strengths, weaknesses and opportunities. In: PLANTA MEDICA. (pp. 798 - 798).

Godwin, A and Choi, J-W and Pedone, E and Balan, S and Jumnah, R and Shaunak, S and Brocchini, S and Zloh, M (2007) Molecular dynamics simulations of proteins with chemically modified disulfide bonds. THEORETICAL CHEMISTRY ACCOUNTS , 117 (2) 259 - 265. 10.1007/s00214-006-0134-0.

Groc, L and Choquet, D and Stephenson, FA and Verrier, D and Manzoni, OJ and Chavis, P (2007) NMDA receptor surface trafficking and synaptic subunit composition are developmentally regulated by the extracellular matrix protein reelin. JOURNAL OF NEUROSCIENCE , 27 (38) 10165 - 10175. 10.1523/JNEUROSCI.1772-07.2007.

Gunaratnam, M and Cuenca, F and Beltran, M and Swank, S and Fletcher, J and Neidle, S (2007) Targeting imatinib-resistant gastrointestinal stromal tumors by down-regulation of KIT gene expression with quadruplex-stabilizing small molecules. MOLECULAR CANCER THERAPEUTICS , 6 (12) 3519S - 3519S.

Gunaratnam, M and Greciano, O and Martins, C and Reszka, AP and Schultes, CM and Morjani, H and Riou, JF and Neidle, S (2007) Mechanism of acridine-based telomerase inhibition and telomere shortening. Biochem Pharmacol , 74 (5) 679 - 689. 10.1016/j.bcp.2007.06.011.

Guo, X and Evans, TR and Somanath, S and Armesilla, AL and Darling, JL and Schatzlein, A and Cassidy, J and Wang, W (2007) In vitro evaluation of cancer-specific NF-kappaB-CEA enhancer-promoter system for 5-fluorouracil prodrug gene therapy in colon cancer cell lines. Br J Cancer , 97 (6) 745 - 754. 10.1038/sj.bjc.6603930.

H

Hadjivassileva, T and Stapleton, PD and Thurston, DE and Taylor, PW (2007) Interactions of pyrrolobenzodiazepine dimers and duplex DNA from methicillin-resistant Staphylococcus aureus. Int J Antimicrob Agents , 29 (6) 672 - 678. 10.1016/j.ijantimicag.2007.01.005.

Heinrich, M (2007) Herbal medicines in health care - Benefits and risks. In: TOXICOLOGY. (pp. 148 - 149).

Heinrich, M and Modarai, M and Kortenkamp, A (2007) CYP inhibitory action of Echinacea preparations differs widely, but is it clinically relevant? In: PLANTA MEDICA. (pp. 823 - 823).

Heinrich, M and Modarai, M and Kortenkamp, A (2007) Drug interactions with Echinacea: does it matter how the product is made? JOURNAL OF PHARMACY AND PHARMACOLOGY , 59 A80 - A80.

Heinrich, M and Nebel, S and Leonti, M (2007) Local European medicinal and food plants - how can they contribute to improved health? In: Hamazaki, T and Nagasawa, T and Okuyama, H, (eds.) In what areas are traditional/alternative medicines useful? (121 - 131). Nakatani Printing: Toyama, Japan.

Hilton, ST and Jones, K (2007) The tandem radical route to indole alkaloids: an unusual rearrangement reaction. ARKIVOC 120 - 128.

Hilton, ST and Jones, K (2007) The tandem radical route to indole alkaloids: an unusual rearrangement reaction. Arkivoc , 2007 (XI) 120 - 128.
An open access publication. A version is also available from UCL Discovery.
 file

K

Ka Po Shiu, W and Gibbons, S (2007) Isolation and characterization of a new dibenzofuran from Hypericum revolutum ssp revolutum Vahl. In: PLANTA MEDICA. (pp. 943 - 943).

Kokubun, T and Shiu, WKP and Gibbons, S (2007) Inhibitory activities of lichen-derived compounds against methicillin- and multidrug-resistant Staphylococcus aureus. PLANTA MEDICA , 73 (2) 176 - 179. 10.1055/s-2006-957070.

L

Lechner, D and Gibbons, S and Bucar, F (2007) Modulation of isoniazid susceptibility of mycobacterial strains by different flavonoids. In: PLANTA MEDICA. (pp. 848 - 848).

Lee, MP and Parkinson, GN and Hazel, P and Neidle, S (2007) Observation of the coexistence of sodium and calcium ions in a DNA G-quadruplex ion channel. J Am Chem Soc , 129 (33) 10106 - 10107. 10.1021/ja0740869.

M

Martins, C and Gunaratnam, M and Stuart, J and Makwana, V and Greciano, O and Reszka, AP and Kelland, LR and Neidle, S (2007) Structure-based design of benzylamino-acridine compounds as G-quadruplex DNA telomere targeting agents. Bioorg Med Chem Lett , 17 (8) 2293 - 2298. 10.1016/j.bmcl.2007.01.056.

Michalet, S and Cartier, G and David, B and Mariotte, A-M and Dijoux-franca, M-G and Kaatz, GW and Stavri, M and Gibbons, S (2007) N-Caffeoylphenalkylamide derivatives as bacterial efflux pump inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , 17 (6) 1755 - 1758. 10.1016/j.bmcl.2006.12.059.

Milroy, LG and Zinzalla, G and Prencipe, G and Michel, P and Ley, SV and Gunaratnam, M and Beltran, M and Neidle, S (2007) Chemical variation of natural-product-like scaffolds: design, synthesis, and biological activity of fused bicyclic acetal derivatives. Angew Chem Int Ed Engl , 46 (14) 2493 - 2496. 10.1002/anie.200604688.

Modarai, M and Gertsch, J and Suter, A and Heinrich, M and Kortenkamp, A (2007) Cytochrome P450 inhibitory action of Echinacea preparations differs widely and co-varies with alkylamide content. J Pharm Pharmacol , 59 (4) 567 - 573. 10.1211/jpp.59.4.0012.

Modarai, M and Wilson, N and Politi, M and Suter, A and Kortenkamp, A and Heinrich, M (2007) Echinacea liquid formulations - NMR spectroscopy and multivariate data analysis of fractions with CYP3A4 inhibitory activity. JOURNAL OF PHARMACY AND PHARMACOLOGY , 59 A63 - A63.

Modarai, M and Wilson, N and Politi, M and Suter, A and Kortenkamp, A and Heinrich, M (2007) Evaluating CYP3A4 inhibitory activity of Echinacea extracts using NMR and multivariate data analysis. In: PLANTA MEDICA. (pp. 990 - 991).

Munde, M and Lee, M and Neidle, S and Arafa, R and Boykin, DW and Liu, Y and Bailly, C and Wilson, WD (2007) Induced fit conformational changes of a "reversed amidine" heterocycle: optimized interactions in a DNA minor groove complex. J Am Chem Soc , 129 (17) 5688 - 5698. 10.1021/ja069003n.

N

Neidle, S (2007) Cancer Drug Design and Discovery. Academic Press

Neidle, S (2007) Methods for studying quadruplex nucleic acids. Methods , 43 (4) 10.1016/j.ymeth.2007.10.001.

Neidle, S (2007) Methods for studying quadruplex nucleic acids. METHODS , 43 (4) 245 - 245. 10.1016/j.ymeth.2007.10.001.

Neidle, S (2007) Principles of Nucleic Acid Structure. Academic Press

O

O'Donnell, G and Gibbons, S (2007) Antibacterial activity of two canthin-6-one alkaloids from Allium neapolitanum. Phytother Res , 21 (7) 653 - 657. 10.1002/ptr.2136.

P

Palmer, AM and Stephenson, FA and Williams, RJ (2007) Society for Medicines Research: 40th Anniversary Symposium. Drug News and Perspectives , 20 (3) 191 - 196.

Parkinson, GN (2007) Nucleic acids research. In: Firm, OJ and Central, NIOHUSP and Press, H, (eds.) Nucleic acids research.

Parkinson, GN and Ghosh, R and Neidle, S (2007) Structural basis for binding of porphyrin to human telomeres. Biochemistry , 46 (9) 2390 - 2397. 10.1021/bi062244n.

Peschel, W and Politi, M and Wilson, N and Constanti, A and Prieto, GJM and Heinrich, M (2007) Cannabis tinctures and extracts - in vitro profiling for cytotoxic and anti-inflammatory effects. In: PLANTA MEDICA. (pp. 841 - 842).

Phan, AT and Kuryavyi, V and Burge, S and Neidle, S and Patel, DJ (2007) Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter. J Am Chem Soc , 129 (14) 4386 - 4392. 10.1021/ja068739h.

Phan, AT and Kuryavyi, V and Burge, S and Neidle, S and Patel, DJ (2007) The unprecedented structure of a G-quadruplex formed in the human c-kit promoter. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , 24 (6) 712 - 713.

Politi, M and Prieto, JM and Heinrich, M (2007) Direct metabolic fingerprinting by NMR spectroscopy as a new method for the analysis of herbal tinctures. In: PLANTA MEDICA. (pp. 903 - 903).

Prieto, JM and Iacopini, P and Cioni, P and Chericoni, S (2007) In vitro activity of the essential oils of Origanum vulgare, Satureja montana and their main constituents in peroxynitrite-induced oxidative processes. FOOD CHEMISTRY , 104 (3) 889 - 895. 10.1016/j.foodchem.2006.01.064.

Prieto-Garcia, JM (2007) La regulacion global de los medicamentos herbarios. Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas , 6 (4) 92 - 101.
An open access publication. A version is also available from UCL Discovery.
 file

Prieto-Garcia, JM and Schaffner, U and Barker, A and Braca, A and Siciliano, T and Boeve, JL (2007) Sequestration of furostanol saponins by Monophadnus sawfly larvae. Journal of Chemical Ecology , 33 (3) 513 - 524. 10.1007/s10886-006-9232-7.

R

Rahman, MM and Gibbons, S (2007) The anti-staphylococcal activity of terpenes from Commiphora molmol Engl. In: PLANTA MEDICA. (pp. 872 - 872).

Rahman, MM and Gibbons, S and Gray, AI (2007) Isoflavanones from Uraria picta and their antimicrobial activity. PHYTOCHEMISTRY , 68 (12) 1692 - 1697. 10.1016/j.phytochem.2007.04.015.

Reed, JE and Neidle, S and Vilar, R (2007) Stabilisation of human telomeric quadruplex DNA and inhibition of telomerase by a platinum-phenanthroline complex. Chem Commun (Camb) (42) 4366 - 4368. 10.1039/b709898g.

Reed, JE and Neidle, S and Vilar, R (2007) Stabilisation of human telomeric quadruplex DNA and inhibition of telomerase by a platinum?phenanthroline complex. Chemical Communications (42) 4366 - 4368. 10.1039/b709898g.

Rivera, D and Obon, C and Inocencio, C and Heinrich, M and Verde, A and Fajardo, J and Palazon, JA (2007) Gathered food plants in the mountains of Castilla-La mancha (Spain): Ethnobotany and Multivariate analysis. ECONOMIC BOTANY , 61 (3) 269 - 289. 10.1663/0013-0001(2007)61[269:GFPITM]2.0.CO;2.

Robins, RJ and Gibbons, S and Marston, A (2007) The fiftieth anniversary meeting of the Phytochemical Society of Europe: Churchill College, Cambridge, 11-14 April 2007 Highlights in the Evolution of Phytochemistry. PHYTOCHEMISTRY , 68 (22-24) 2699 - 2704. 10.1016/j.phytochem.2007.10.003.

S

Shiu, KP and Gibbons, S (2007) The anti-staphylococcal activity of Hypericum species. In: PLANTA MEDICA. (pp. 872 - 873).

Smith, E and Gibbons, S (2007) 2 beta-acetoxyferruginol - a new antibacterial abietane diterpene from Prumnopitys andina. In: PLANTA MEDICA. (pp. 807 - 807).

Smith, E and Gibbons, S (2007) Myrceocommunic acid - a labdane diterpene with activity against Staphylococcus aureus and Propionibacterium acnes. In: PLANTA MEDICA. (pp. 944 - 944).

Smith, EC and Kaatz, GW and Seo, SM and Wareham, N and Williamson, EM and Gibbons, S (2007) The phenolic diterpene totarol inhibits multidrug efflux pump activity in Staphylococcus aureus. Antimicrob Agents Chemother , 51 (12) 4480 - 4483. 10.1128/AAC.00216-07.

Smith, EC and Williamson, EM and Wareham, N and Kaatz, GW and Gibbons, S (2007) Antibacterials and modulators of bacterial resistance from the immature cones of Chamaecyparis lawsoniana. Phytochemistry , 68 (2) 210 - 217. 10.1016/j.phytochem.2006.10.001.

Stapleton, PD and Shah, S and Ehlert, K and Hara, Y and Taylor, PW (2007) The beta-lactam-resistance modifier (-)-epicatechin gallate alters the architecture of the cell wall of Staphylococcus aureus. Microbiology , 153 (Pt 7) 2093 - 2103. 10.1099/mic.0.2007/007807-0.

Stavri, M and Gibbons, S (2007) Antibacterial constituents from Plectranthus ciliatus. In: PLANTA MEDICA. (pp. 873 - 873).

Stavri, M and Gibbons, S (2007) New diterpenes from Plectranthus emstii. In: PLANTA MEDICA. (pp. 873 - 873).

Stavri, M and Piddock, LJ and Gibbons, S (2007) Bacterial efflux pump inhibitors from natural sources. J Antimicrob Chemother , 59 (6) 1247 - 1260. 10.1093/jac/dkl460.

T

Todd, AK and Haider, SM and Parkinson, GN and Neidle, S (2007) Sequence occurrence and structural uniqueness of a G-quadruplex in the human c-kit promoter. Nucleic Acids Res , 35 (17) 5799 - 5808. 10.1093/nar/gkm609.
An open access publication. A version is also available from UCL Discovery.
 file

U

Uddin, SJ and Nahar, L and Shilpi, JA and Shoeb, M and Borkowski, T and Gibbons, S and Middleton, M and Byres, M and Sarker, SD (2007) Gedunin, a limonoid from Xylocarpus granatum, inhibits the growth of CaCo-2 colon cancer cell line in vitro. PHYTOTHERAPY RESEARCH , 21 (8) 757 - 761. 10.1002/ptr.2159.

V

Verbic, TZ and Drakulic, BJ and Zloh, MF and Pecelj, JR and Popovic, GV and Juranic, IO (2007) An LFER study of the protolytic equililbria of 4-aryl-2,4-dioxolbutanoic acids in aqueous solutions. JOURNAL OF THE SERBIAN CHEMICAL SOCIETY , 72 (12) 1201 - 1216. 10.2298/JSC0712201V.
An open access publication

W

White, EW and Tanious, F and Ismail, MA and Reszka, AP and Neidle, S and Boykin, DW and Wilson, WD (2007) Structure-specific recognition of quadruplex DNA by organic cations: Influence of shape, substituents and charge. BIOPHYSICAL CHEMISTRY , 126 (1-3) 140 - 153. 10.1016/j.bpc.2006.06.006.

White, EW and Tanious, F and Ismail, MA and Reszka, AP and Neidle, S and Boykin, DW and Wilson, WD (2007) Structure-specific recognition of quadruplex DNA by organic cations: influence of shape, substituents and charge. Biophys Chem , 126 (1-3) 140 - 153. 10.1016/j.bpc.2006.06.006.

Whitlock, GA and Wakenhut, F and Stobie, A and Fish, PV and Fray, MJ (2007) Discovery of PF-184298, a dual serotonin/noradrenaline reuptake inhibitor. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY , 233 590 - 590.

Woon, EC and Arcieri, M and Wilderspin, AF and Malkinson, JP and Searcey, M (2007) Solid-phase synthesis of chlorofusin analogues. J Org Chem , 72 (14) 5146 - 5151. 10.1021/jo070450a.

X

Xiao, ZY and Mu, Q and Shiu, WK and Zeng, YH and Gibbons, S (2007) Polyisoprenylated benzoylphloroglucinol derivatives from Hypericum sampsonii. J Nat Prod , 70 (11) 1779 - 1782. 10.1021/np0704147.

Y

Yang, M and Davies, GJ and Davis, BG (2007) A glycosynthase catalyst for the synthesis of flavonoid glycosides. Angew Chem Int Ed Engl , 46 (21) 3885 - 3888. 10.1002/anie.200604177.

Z

Zhao, YH and Abraham, MH and Ibrahim, A and Fish, PV and Cole, S and Lewis, ML and de Groot, MJ and Reynolds, DP (2007) Predicting penetration across the blood-brain barrier from simple descriptors and fragmentation schemes. J Chem Inf Model , 47 (1) 170 - 175. 10.1021/ci600312d.

Zloh, M and Bucar, F and Gibbons, S (2007) Quantum chemical studies on structure activity relationship of natural product polyacetylenes. THEORETICAL CHEMISTRY ACCOUNTS , 117 (2) 247 - 252. 10.1007/s00214-006-0148-7.

Zloh, M and Gibbons, S (2007) The role of small molecule-small molecule interactions in overcoming biological barriers for antibacterial drug action. THEORETICAL CHEMISTRY ACCOUNTS , 117 (2) 231 - 238. 10.1007/s00214-006-0149-6.

Zloh, M and Shaunak, S and Balan, S and Brocchini, S (2007) Identification and insertion of 3-carbon bridges in protein disulfide bonds: a computational approach. Nat Protoc , 2 (5) 1070 - 1083. 10.1038/nprot.2007.119.

This list was generated on Wed May 22 03:22:05 2013 BST.