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Number of items at this level: 35.

Article

Fletcher, H.A. and Donoghue, H.D. and Taylor, G.M. and van der Zanden, A.G.M. and Spigelman, M. (2003) Molecular analysis of Mycobacterium tuberculosis DNA from a family of 18th century Hungarians. Microbiology , 149 (1) pp. 143-151. 10.1099/mic.0.25961-0.
An open access version is available from UCL Discovery
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Chang, J.-S. and Huggett, J.F. and Dheda, K. and Zumla, A. and Rook, G.A.W. and Kim, L.U. (2006) Myobacterium tuberculosis induces selective up-regulation of TLRs in the mononuclear leukocytes of patients with active pulmonary tuberculosis. The Journal of Immunology , 176 (5) pp. 3010-3018.

Chintu, C. and Mudenda, V. and Lucas, S. and Nunn, A. and Lishimpi, K. and Maswahu, D. and Kasolo, F. and Mwaba, P. and Bhat, G. and Terunuma, H. and Zumla, A. (2002) Lung diseases at necropsy in African children dying from respiratory illnesses: a descriptive necropsy study. The Lancet , 360 (9338) pp. 985-990. 10.1016/S0140-6736(02)11082-8.

Dheda, K and Chang, JS and Breen, RAM and Haddock, JA and Lipman, MC and Kim, LU and Huggett, JF and Johnson, MA and Rook, GAW and Zumla, A (2005) Expression of a novel cytokine, IL-4deltaf in HIV and HIV-tuberculosis co-infection. AIDS , 19 (15) 1601 - 1606.

Dheda, K. and Chang, J.-S. and Breen, R.A.M. and Kim, L.U. and Haddock, J.A. and Huggett, J.F. and Johnson, M.A. and Rook, G.A.W. and Zumla, A. (2005) In vivo and In vitro studies of a novel cytokine, interleukin 4 2, in pulmonary tuberculosis. American Journal of Respiratory and Critical Care Medicine , 172 (4) pp. 501-508. 10.1164/rccm.200502-278OC.

Dheda, K. and Lalvani, A. and Miller, R. and Scott, G. and Booth, H. and Johnson, M.A. and Zumla, A. and Rook, G.A.W. (2005) Performance of a T-cell-based diagnostic test for tuberculosis infection in HIV-infected individuals is independent of CD4 cell count. AIDS , 19 (17) pp. 2038-2041.

Donoghue, HD (2009) Human tuberculosis - an ancient disease, as elucidated by ancient microbial biomolecules. MICROBES INFECT , 11 (14-15) 1156 - 1162. 10.1016/j.micinf.2009.08.008.
An open access version is available from UCL Discovery
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Donoghue, HD and Hershkovitz, I and Minnikin, DE and Besra, GS and Lee, OYC and Galili, E and Greenblatt, CL and Lemma, E and Spigelman, M and Bar-Gal, GK (2009) Biomolecular archaeology of ancient tuberculosis: response to "Deficiencies and challenges in the study of ancient tuberculosis DNA" by Wilbur et al. (2009). J ARCHAEOL SCI , 36 (12) 2797 - 2804. 10.1016/j.jas.2009.09.007.
An open access version is available from UCL Discovery
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Donoghue, HD and Holton, J and Spigelman, M (2001) PCR primers that can detect low levels of Mycobacterium leprae DNA. JOURNAL OF MEDICAL MICROBIOLOGY , 50 (2) 177 - 182.

Donoghue, HD and Lee, OYC and Minnikin, DE and Besra, GS and Taylor, JH and Spigelman, M (2010) Tuberculosis in Dr Granville's mummy: a molecular re-examination of the earliest known Egyptian mummy to be scientifically examined and given a medical diagnosis. Proceedings of the Royal Society B , 277 (1678) 51 - 56. 10.1098/rspb.2009.1484.
An open access version is available from UCL Discovery
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Donoghue, HD and Marcsik, A and Matheson, C and Vernon, K and Nuorala, E and Molto, JE and Greenblatt, CL and Spigelman, M (2005) Co-infection of Mycobacterium tuberculosis and Mycobacterium leprae in human archaeological samples: a possible explanation for the historical decline of leprosy. P R SOC B , 272 (1561) 389 - 394. 10.1098/rspb.2004.2966.

Donoghue, HD and Spigelman, M and Greenblatt, CL and Lev-Maor, G and Bar-Gal, GK and Matheson, C and Vernon, K and Nerlich, AG and Zink, AR (2004) Tuberculosis: from prehistory to Robert Koch, as revealed by ancient DNA. LANCET INFECT DIS , 4 (9) 584 - 592.

Drewe, JA and Mwangi, D and Donoghue, HD and Cromie, RL (2009) PCR analysis of the presence and location of Mycobacterium avium in a constructed reed bed, with implications for avian tuberculosis control. FEMS MICROBIOL ECOL , 67 (2) 320 - 328. 10.1111/j.1574-6941.2008.00618.x.
An open access version is available from UCL Discovery
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Fletcher, HA and Donoghue, HD and Holton, J and Pap, I and Spigelman, M (2003) Widespread occurrence of Mycobacterium tuberculosis DNA from 18th-19th century Hungarians. AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY , 120 (2) 144 - 152. 10.1002/ajpa.10114.
An open access version is available from UCL Discovery
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Hernandez-Pando, R and Aguilar, D and Hernandez, MLG and Orozco, H and Rook, G (2004) Pulmonary tuberculosis in BALB/c mice with nonfunctional IL-4 genes: changes in the inflammatory effects of TNF-alpha and in the regulation of fibrosis. EUR J IMMUNOL , 34 (1) 174 - 183. 10.1002/eji.200324253.

Hernandez-Pando, R. and Aguilar-Leon, D. and Orozco, H. and Serrano, A. and Ahlem, C. and Trauger, R. and Schramm, B. and Reading, C. and Frincke, J. and Rook, G.A.W. (2005) 16-Bromoepiandrosterone restores T helper cell type 1 activity and accelerates chemotherapy-induced bacterial clearance in a model of progressive pulmonary tuberculosis. Journal of Infectious Diseases , 191 (2) pp. 299-306. 10.1086/426453.

Hershkovitz, I and Donoghue, HD and Minnikin, DE and Besra, GS and Lee, OYC and Gernaey, AM and Galili, E and Eshed, V and Greenblatt, CL and Lemma, E and Bar-Gal, GK and Spigelman, M (2008) Detection and Molecular Characterization of 9000-Year-Old Mycobacterium tuberculosis from a Neolithic Settlement in the Eastern Mediterranean. PLOS ONE , 3 (10) , Article e3426. 10.1371/journal.pone.0003426.
An open access publication. A version is also available from UCL Discovery.
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Matheson, CD and Vernon, KK and Lahti, A and Fratpietro, R and Spigelman, M and Gibson, S and Greenblatt, CL and Donoghue, HD (2009) Molecular Exploration of the First-Century Tomb of the Shroud in Akeldama, Jerusalem. PLOS ONE , 4 (12) , Article e8319. 10.1371/journal.pone.0008319.
An open access publication. A version is also available from UCL Discovery.
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Monot, M and Honore, N and Garnier, T and Zidane, N and Sherafi, D and Paniz-Mondolfi, A and Matsuoka, M and Taylor, GM and Donoghue, HD and Bouwman, A and Mays, S and Watson, C and Lockwood, D and Khamispour, A and Dowlati, Y and Shen, JP and Rea, TH and Vera-Cabrera, L and Stefani, MM and Banu, S and Macdonald, M and Sapkota, BR and Spencer, JS and Thomas, J and Harshman, K and Singh, P and Busso, P and Gattiker, A and Rougemont, J and Brennan, PJ and Cole, ST (2009) Comparative genomic and phylogeographic analysis of Mycobacterium leprae. NAT GENET , 41 (12) 1282 - U39. 10.1038/ng.477.
An open access version is available from UCL Discovery
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Mwinga, A. and Nunn, A. and Ngwira, B. and Chintu, C. and Warndorff, D. and Fine, P. and Darbyshire, J. and Zumla, A. (2002) Mycobacterium vaccae (SRL172) immunotherapy as an adjunct to standard antituberculosis treatment in HIV-infected adults with pulmonary tuberculosis: a randomised placebo-controlled trial. The Lancet , 360 (9339) pp. 1050-1055. 10.1016/S0140-6736(02)11141-X.

O'Mahony, R and Basset, C and Holton, J and Vaira, D and Roitt, I (2005) Comparison of image analysis software packages in the assessment of adhesion of microorganisms to mucosal epithelium using confocal laser scanning microscopy. Journal of Microbiological Methods , 61 (1) 105 - 126.
An open access version is available from UCL Discovery
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O'Mahony, R and Vaira, D and Holton, J and Basset, C (2004) Helicobacter pylori: current status and future prospects. Science Progress , 87 (4) 269 - 296.
An open access version is available from UCL Discovery
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Pinhasi, R and Foley, R and Donoghue, HD (2006) Reconsidering the antiquity of leprosy. SCIENCE , 312 (5775) 846 - 846.

Pulimood, AB and Peter, S and Rook, GWA and Donoghue, HD (2008) In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease. AM J CLIN PATHOL , 129 (6) 846 - 851. 10.1309/DKKECWQWMG4J23E3.
An open access version is available from UCL Discovery
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Rook, GA and Martinelli, R and Brunet, LR (2005) Modelling gene-environment interactions in Th1- and Th2-dominated diseases of laboratory animals. Ernst Schering Res Found Workshop (50) 45 - 68.
An open access version is available from UCL Discovery
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Rook, GAW and Dheda, K and Zumla, A (2005) Do successful tuberculosis vaccines need to be immunoregulatory rather than merely Th1-boosting? VACCINE , 23 (17-18) 2115 - 2120.
An open access version is available from UCL Discovery
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Rothschild, BM and Martin, LD and Lev, G and Bercovier, H and Bar-Gal, GK and Greenblatt, C and Donoghue, H and Spigelman, M and Brittain, D (2001) Mycobacterium tuberculosis complex DNA from an extinct bison dated 17,000 years before the present. Clinical Infectious Diseases , 33 (3) 305 - 311. 10.1086/321886.
An open access version is available from UCL Discovery
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Seah, GT and Rook, GAW (2001) IL-4 influences apoptosis of mycobacterium-reactive lymphocytes in the presence of TNF-alpha. J IMMUNOL , 167 (3) 1230 - 1237.

Spigelman, M and Berger, L and Pinhasi, R and Donoghue, HD and Chaplin, S (2008) John Hunter's post-mortem examination of George Grenville (1712-1770). Bulletin of the Royal College of Surgeons of England , 90 (10) 338 - 339. 10.1308/147363508X337163.
An open access version is available from UCL Discovery
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Spigelman, M and Donoghue, HD (2001) Brief communication: Unusual pathological condition in the lower extremities of a skeleton from ancient Israel. AM J PHYS ANTHROPOL , 114 (1) 92 - 93.
An open access version is available from UCL Discovery
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Spigelman, M and Matheson, C and Lev, G and Greenbaltt, C and Donoghue, HD (2002) Confirmation of the presence of Mycobacterium-tuberculosis complex-specific DNA in three archaeological specimens. INT J OSTEOARCHAEOL , 12 (6) 393 - 401.
An open access version is available from UCL Discovery
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Spigelman, M. and Pap, I. and Donoghue, H.D. (2006) A death from Langerhans cell histiocytosis and tuberculosis in 18th Century Hungary – what palaeopathology can tell us today. Leukemia , 20 (4) pp. 740-742. 10.1038/sj.leu.2404103.

Zink, AR and Spigelman, M and Schraut, B and Greenblatt, CL and Nerlich, AG and Donoghue, HD (2006) Leishmaniasis in ancient Egypt and upper Nubia. EMERG INFECT DIS , 12 (10) 1616 - 1617.
An open access publication. A version is also available from UCL Discovery.
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Book chapter

Donoghue, HD (2008) Molecular palaeopathology of human infectious disease. In: Pinhasi, R and Mays, S, (eds.) Advances in human palaeopathology. (147 - 176). John Wiley & Sons Ltd: Chichester, UK.

Donoghue, HD (2008) Palaeomicrobiology of tuberculosis. In: Raoult, D and Drancourt, M, (eds.) Paleomicrobiology - Past Human Infections. (75 - 97). Springer-Verlag GmbH: Berlin Heidelberg.
An open access version is available from UCL Discovery
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This list was generated on Tue Feb 14 14:05:19 2012 GMT.