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Number of items at this level: 41.

A

Aguilar, S and Nye, E and Chan, J and Loebinger, M and Spencer-Dene, B and Fisk, N and Stamp, G and Bonnet, D and Janes, SM (2007) Murine but not human mesenchymal stem cells generate osteosarcoma-like lesions in the lung. Stem Cells , 25 (6) 1586 - 1594. 10.1634/stemcells.2006-0762.

B

Bellingan, GJ and Xu, P and Cooksley, H and Cauldwell, H and Shock, A and Bottoms, S and Haslett, C and Mutsaers, SE and Laurent, GJ (2002) Adhesion molecule-dependent mechanisms regulate the rate of macrophage clearance during the resolution of peritoneal inflammation. J EXP MED , 196 (11) 1515 - 1521. 10.1084/jem.20011794.
An open access version is available from UCL Discovery
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Brown, JS and Hussell, T and Gilliland, SM and Holden, DW and Paton, JC and Ehrenstein, MR and Walport, MJ and Botto, M (2002) The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice. P NATL ACAD SCI USA , 99 (26) 16969 - 16974. 10.1073/pnas.012669199.

C

Chambers, RC and Leoni, P and Kaminski, N and Laurent, GJ and Heller, RA (2003) Global expression profiling of fibroblast responses to transforming growth factor-beta(1) reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching. AM J PATHOL , 162 (2) 533 - 546.

Chua, F and Dunsmore, SE and Clingen, PH and Mutsaers, SE and Shapiro, SD and Segal, AW and Roes, J and Laurent, GJ (2007) Mice lacking neutrophil elastase are resistant to bleomycin-induced pulmonary fibrosis. AM J PATHOL , 170 (1) 65 - 74. 10.2353/ajpath.2007.060352.

Coker, RK and Laurent, GJ and Jeffery, PK and du Bois, RM and Black, CM and McAnulty, RJ (2001) Localisation of transforming growth factor beta(1) and beta(3) mRNA transcripts in normal and fibrotic human lung. THORAX , 56 (7) 549 - 556.
An open access version is available from UCL Discovery
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D

Deng, X. (2008) Identification of PAR1-G protein signalling pathways involved in thrombin-induced CCL2/MCP-1 production. Doctoral thesis, UCL (University College London).

F

Foley-Comer, AJ and Herrick, SE and Al-Mishlab, T and Prele, CM and Laurent, GJ and Mutsaers, SE (2002) Evidence for incorporation of free-floating mesothelial cells as a mechanism of serosal healing. J CELL SCI , 115 (7) 1383 - 1389.

H

Hill, MR and Briggs, L and Montaño, MM and Estrada, A and Laurent, GJ and Selman, M and Pardo, A (2004) Promoter variants in tissue inhibitor of metalloproteinase-3 (TIMP-3) protect against susceptibility in pigeon breeders' disease. Thorax , 59 (7) 586 - 590.
An open access version is available from UCL Discovery
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Hill, MR and Papafili, A and Booth, H and Lawson, P and Hubner, M and Beynon, H and Read, C and Linclahl, G and Marshall, RP and McAnulty, RJ and Laurent, GJ (2006) Functional prostaglandin-endoperoxide synthase 2 polymorphism predicts poor outcome in sarcoidosis. AM J RESP CRIT CARE , 174 (8) 915 - 922. 10.1164/rccm.200512-1839OC.

Hodges, RJ and Jenkins, RG and Wheeler-Jones, CPD and Copeman, DM and Bottoms, SE and Bellingan, GJ and Nanthakumar, CB and Laurent, GJ and Hart, SL and Foster, ML and McAnulty, RJ (2004) Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E-2 production. AM J PATHOL , 165 (5) 1663 - 1676.
An open access version is available from UCL Discovery
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Howell, DCJ and Goldsack, NR and Marshall, RP and McAnulty, RJ and Starke, R and Purdy, G and Laurent, GJ and Chambers, RC (2001) Direct thrombin inhibition reduces lung collagen, accumulation, and connective tissue growth factor mRNA levels in bleomycin-induced pulmonary fibrosis. AM J PATHOL , 159 (4) 1383 - 1395.

Howell, DCJ and Johns, RH and Lasky, JA and Shan, B and Scotton, CJ and Laurent, GJ and Chambers, RC (2005) Absence of proteinase-activated receptor-1 signaling affords protection from bleomycin-induced lung inflammation and fibrosis. AM J PATHOL , 166 (5) 1353 - 1365.
An open access publication

Hurst, J and Donaldson, GC and Wilkinson, TM and Perera, WR and Wedzicha, JA (2005) Epidemiological relationships between the common cold and exacerbation frequency in COPD. European Respiratory Journal , 26 (5) 846 - 852. 10.1183/09031936.05.00043405.

Hurst, J and Wilkinson, TM and Perera, WR and Donaldson, GC and Wedzicha, JA (2005) Relationships among bacteria, upper airway, lower airway, and systemic inflammation in COPD. Chest , 127 (4) 1219 - 1226. 10.1378/chest.127.4.1219.

Hurst, J.R. and Perera, W.R. and Wilkinson, T.M.A. and Donaldson, G.C. and Wedzicha, J.A. (2006) Systemic and upper and lower airway inflammation at exacerbation of chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine , 173 (1) pp. 71-78. 10.1164/rccm.200505-704OC.

Hurst, JR and Donaldson, GC and Perera, WR and Wilkinson, TMA and Bilello, JA and Hagan, GW and Vessey, RS and Wedzicha, JA (2006) Use of plasma biomarkers at exacerbation of chronic obstructive pulmonary disease. AM J RESP CRIT CARE , 174 (8) 867 - 874. 10.1164/rccm.200604-506OC.

Hyams, C.J. (2010) The role of the Streptococcus pneumoniae capsule in interactions with complement and phagocytes. Doctoral thesis, UCL (University College London).
An open access version is available from UCL Discovery
 file

J

Janes, S.M. and Ofstad, T.A. and Campbell, D.H. and Watt, F.M. and Prowse, D.M. (2004) Transient activation of FOXN1 in keratinocytes induces a transcriptional programme that promotes terminal differentiation: contrasting roles of FOXN1 and Akt. Journal of Cell Science , 117 (18) pp. 4157-4168. 10.1242/jcs.01302.
An open access version is available from UCL Discovery
 file

Janes, S.M. and Rahman, N.M. and Davies, R.J.O. and Lee, Y.C.G. (2007) Catheter-tract metastases associated with chronic indwelling pleural catheters. Chest , 131 (4) pp. 1232-1234. 10.1378/chest.06-2353.

Janes, SM and Watt, FM (2004) Switch from alpha v beta 5 to alpha v beta 6 integrin expression protects squamous cell carcinomas from anoikis. J CELL BIOL , 166 (3) 419 - 431. 10.1083/jcb.200312074.
An open access version is available from UCL Discovery
 file

Jenkins, R.G. and Meng, Q.-H. and Hodges, R.J. and Lee, L.K. and Bottoms, S.E.W. and Laurent, G.J. and Willis, D. and Shamlou, P.A. and McAnulty, R.J. and Hart, S.L. (2003) Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo. Gene Therapy , 10 (12) pp. 1026-1034. 10.1038/sj.gt.3301963.

Jenkins, R.G. and Meng, Q.-H. and Hodges, R.J. and Lee, L.K. and Bottoms, S.E.W. and Laurent, G.J. and Willis, D. and Shamlou, P.A. and McAnulty, R.J. and Hart, S.L. (2003) Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo. Gene Therapy , 10 (12) pp. 1026-1034. 10.1038/sj.gt.3301963.

Jenkins, RG and Su, X and Su, G and Scotton, CJ and Camerer, E and Laurent, GJ and Davis, GE and Chambers, RC and Matthay, MA and Sheppard, D (2006) Ligation of protease-activated receptor 1 enhances alpha(v)beta(6) integrin-dependent TGF-beta activation and promotes acute lung injury. J CLIN INVEST , 116 (6) 1606 - 1614. 10.1172/JCI27183.
An open access version is available from UCL Discovery
 file

K

Keerthisingam, CB and Jenkins, RG and Harrison, NK and Hernandez-Rodriguez, NA and Booth, H and Laurent, GJ and Hart, SL and Foster, ML and McAnulty, RJ (2001) Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-beta in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice. AM J PATHOL , 158 (4) 1411 - 1422.

L

Lee, Y.C. and Knight, D.A. and Lane, K.B. and Cheng, D.S. and Koay, M.A. and Teixeira, L.R. and Nesbitt, J.C. and Chambers, R.C. and Thompson, P.J. and Light, R.W. (2004) Activation of proteinase-activated receptor-2 in mesothelial cells induces pleural inflammation. AJP Lung Cellular and Molecular Physiology , 288 (4) L734-L740. 10.1152/ajplung.00173.2004.

Lee, YC and Baumann, MH and Maskell, NA and Waterer, GW and Eaton, TE and Davies, RJ and Heffner, JE and Light, RW (2003) Pleurodesis practice for malignant pleural effusions in five English-speaking countries: survey of pulmonologists. Chest , 124 (6) 2229 - 2238. 10.1378/chest.124.6.2229.

Lee, YC and Malkerneker, D and Thompson, PJ and Lane, KB and Light, RW (2002) Transforming factor beta induces vascular endothelial growth factor elaboration by pleural mesothelial cells in vivo and in vitro. American Journal of Respiratory and Critical Care Medicine , 165 (1) 88 - 94. 10.1164/rccm2104006.

Lee, YC and Teixeira, LR and Devin, CJ and Vaz, MAC and Vargas, FS and Thompson, PJ and Lane, KB and Light, RW (2001) Transforming growth factor Beta 2 induces pleurodesis significantly faster than talc. American Journal of Respiratory and Critical Care Medicine , 163 640 - 644.

Lindahl, GE and Chambers, RC and Papakrivopoulou, J and Dawson, SJ and Jacobsen, MC and Bishop, JE and Laurent, GJ (2002) Activation of fibroblast procollagen alpha 1(I) transcription by mechanical strain is transforming growth factor-beta-dependent and involves increased binding of CCAAT-binding factor (CBF/NF-Y) at the proximal promoter. J BIOL CHEM , 277 (8) 6153 - 6161. 10.1074/jbc.M108966200.
An open access publication

Loebinger, M.R. (2009) Mesenchymal stem cells as vectors for anti-tumour therapy. Doctoral thesis, UCL (University College London).
An open access version is available from UCL Discovery
 file

M

Marshall, R.P. and Webb, S. and Bellingan, G.J. and Montgomery, H.E. and Chaudhari, B. and McAnulty, R.J. and Humphries, S.E. and Hill, M.R. and Laurent, G.J. (2002) Angiotensin converting enzyme insertion/deletion polymorphism is associated with susceptibility and outcome in acute respiratory distress syndrome. American Journal of Respiratory and Critical Care Medicine , 166 (5) pp. 646-650. 10.1164/rccm.2108086.

McCaughan, F. (2009) 3q amplification in preinvasive lesions of the bronchial epithelium. Doctoral thesis, UCL (University College London).

Murray-Rust, J. and Leiper, J. and McAlister, M. and Phelan, J. and Tilley, S. and Maria, J.S. and Vallance, P. and McDonald, N. (2001) Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase. Nature Structural Biology , 8 (8) pp. 679-683. 10.1038/90387.

P

Papafili, A. and Hill, M.R. and Brull, D.J. and McAnulty, R.J. and Marshall, R.P. and Humphries, S.E. and Laurent, G.J. (2002) Common promoter variant in cyclooxygenase-2 represses gene expression: evidence of role in acute-phase inflammatory response. Arteriosclerosis Thrombosis and Vascular Biology , 22 (10) pp. 1631-1636. 10.1161/01.ATV.0000030340.80207.C5.
An open access version is available from UCL Discovery
 file

R

Reinhardt, AK and Bottoms, SE and Laurent, GJ and McAnulty, RJ (2005) Quantification of collagen and proteoglycan deposition in a murine model of airway remodelling. RESP RES , 6 , Article 30. 10.1186/1465-9921-6-30.
An open access publication. A version is also available from UCL Discovery.
 file

S

Scotton, C.J. and Chambers, R.C. (2010) Editorial: Bleomycin revisited: towards a more representative model of IPF? The American Journal of Physiology - Lung Cellular and Molecular Physiology (In press).

T

Traherne, JA and Hill, MR and Hysi, P and D'Amato, M and Broxholme, J and Mott, R and Moffatt, MF and Cookson, WO (2003) LD mapping of maternally and non-maternally derived alleles and atopy in FcepsilonRI-beta. Human Molecular Genetics , 12 (20) 2577 - 2585. 10.1093/hmg/ddg290.

Y

Yuste, J and Ali, S and Sriskandan, S and Hyams, C and Botto, M and Brown, JS (2006) Roles of the alternative complement pathway and C1q during innate immunity to Streptococcus pyogenes. J IMMUNOL , 176 (10) 6112 - 6120.

Yuste, J and Botto, M and Paton, JC and Holden, DW and Brown, JS (2005) Additive inhibition of complement deposition by pneumolysin and PspA facilitates Streptococcus pneumoniae septicemia. J IMMUNOL , 175 (3) 1813 - 1819.

Yuste, J. and Botto, M. and Bottoms, S.E. and Brown, J.S. (2007) Serum amyloid P aids complement-mediated immunity to Streptococcus pneumoniae. PLoS Pathogens , 3 (9) e120. 10.1371/journal.ppat.0030120.
An open access publication. A version is also available from UCL Discovery.
 file

This list was generated on Tue Feb 14 14:35:38 2012 GMT.